Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4 von Lin, Jimmy C, Wunderlich, John R, Prickett, Todd D, Yates, Kristin E, Cruz, Pedro, Agrawal, Neena S, Cronin, Julia C, Samuels, Yardena, Wei, Xiaomu, Rosenberg, Steven A

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Clinical applications of next generation sequencing in cancer: from panels, to exomes, to genomes von Shen, Tony, Pajaro-Van de Stadt, Stefan Hans, Yeat, Nai Chien, Lin, Jimmy C-H

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Recurrent inactivating RASA2 mutations in melanoma von Arafeh, Rand, Qutob, Nouar, Emmanuel, Rafi, Keren-Paz, Alona, Madore, Jason, Elkahloun, Abdel, Wilmott, James S, Gartner, Jared J, Di Pizio, Antonella, Winograd-Katz, Sabina, Sindiri, Sivasish, Rotkopf, Ron, Dutton-Regester, Ken, Johansson, Peter, Pritchard, Antonia L, Waddell, Nicola, Hill, Victoria K, Lin, Jimmy C, Hevroni, Yael, Rosenberg, Steven A, Khan, Javed, Ben-Dor, Shifra, Niv, Masha Y, Ulitsky, Igor, Mann, Graham J, Scolyer, Richard A, Hayward, Nicholas K, Samuels, Yardena

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Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers von Leary, Rebecca J, Lin, Jimmy C, Cummins, Jordan, Boca, Simina, Wood, Laura D, Parsons, D. Williams, Jones, Siân, Sjöblom, Tobias, Park, Ben-Ho, Parsons, Ramon, Willis, Joseph, Dawson, Dawn, Willson, James K.V, Nikolskaya, Tatiana, Nikolsky, Yuri, Kopelovich, Levy, Papadopoulos, Nick, Pennacchio, Len A, Wang, Tian-Li, Markowitz, Sanford D, Parmigiani, Giovanni, Kinzler, Kenneth W, Vogelstein, Bert, Velculescu, Victor E

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Frequent mutations in the MITF pathway in melanoma von Cronin, Julia C., Wunderlich, John, Loftus, Stacie K., Prickett, Todd D., Wei, Xiaomu, Ridd, Katie, Vemula, Swapna, Burrell, Allison S., Agrawal, Neena S., Lin, Jimmy C., Banister, Carolyn E., Buckhaults, Phillip, Rosenberg, Steven A., Bastian, Boris C., Pavan, William J., Samuels, Yardena

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Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells von Robbins, Paul F, Lu, Yong-Chen, El-Gamil, Mona, Li, Yong F, Gross, Colin, Gartner, Jared, Lin, Jimmy C, Teer, Jamie K, Cliften, Paul, Tycksen, Eric, Samuels, Yardena, Rosenberg, Steven A

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Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma von Gartner, Jared J, Davis, Sean, Wei, Xiaomu, Lin, Jimmy C, Trivedi, Niraj S, Teer, Jamie K, Meltzer, Paul S, Rosenberg, Steven A, Samuels, Yardena

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Somatic Mutations in MAP3K5 Attenuate Its Proapoptotic Function in Melanoma through Increased Binding to Thioredoxin von Prickett, Todd D., Zerlanko, Brad, Gartner, Jared J., Parker, Stephen C.J., Dutton-Regester, Ken, Lin, Jimmy C., Teer, Jamie K., Wei, Xiaomu, Jiang, Jiji, NISC Comparative Sequencing Program, Chen, Guo, Davies, Michael A., Gershenwald, Jeffrey E., Robinson, William, Robinson, Steven, Hayward, Nicholas K., Rosenberg, Steven A., Margulies, Elliott H., Samuels, Yardena

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Exome sequencing identifies GRIN2A as frequently mutated in melanoma von Wei, Xiaomu, Walia, Vijay, Lin, Jimmy C, Teer, Jamie K, Prickett, Todd D, Gartner, Jared, Davis, Sean, Stemke-Hale, Katherine, Davies, Michael A, Gershenwald, Jeffrey E, Robinson, William, Robinson, Steven, Rosenberg, Steven A, Samuels, Yardena

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Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma von Wei, Xiaomu, Prickett, Todd D, Viloria, Cristina G, Molinolo, Alfredo, Lin, Jimmy C, Cardenas-Navia, Isabel, Cruz, Pedro, Rosenberg, Steven A, Davies, Michael A, Gershenwald, Jeffrey E, López-Otín, Carlos, Samuels, Yardena

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MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research von Chang, Wendy, Brohl, Andrew S, Patidar, Rajesh, Sindiri, Sivasish, Shern, Jack F, Wei, Jun S, Song, Young K, Yohe, Marielle E, Gryder, Berkley, Zhang, Shile, Calzone, Kathleen A, Shivaprasad, Nityashree, Wen, Xinyu, Badgett, Thomas C, Miettinen, Markku, Hartman, Kip R, League-Pascual, James C, Trahair, Toby N, Widemann, Brigitte C, Merchant, Melinda S, Kaplan, Rosandra N, Lin, Jimmy C, Khan, Javed

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Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma von Gartner, Jared J., Parker, Stephen C. J., Prickett, Todd D., Dutton-Regester, Ken, Stitzel, Michael L., Lin, Jimmy C., Davis, Sean, Simhadri, Vijaya L., Jha, Sujata, Katagiri, Nobuko, Gotea, Valer, Teer, Jamie K., Wei, Xiaomu, Morken, Mario A., Bhanot, Umesh K., Chen, Guo, Elnitski, Laura L., Davies, Michael A., Gershenwald, Jeffrey E., Carter, Hannah, Karchin, Rachel, Robinson, William, Robinson, Steven, Rosenberg, Steven A., Collins, Francis S., Parmigiani, Giovanni, Komar, Anton A., Kimchi-Sarfaty, Chava, Hayward, Nicholas K., Margulies, Elliott H., Samuels, Yardena

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Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma von Samuels, Yardena, Prickett, Todd D, Wei, Xiaomu, Cardenas-Navia, Isabel, Teer, Jamie K, Lin, Jimmy C, Walia, Vijay, Gartner, Jared, Jiang, Jiji, Cherukuri, Praveen F, Molinolo, Alfredo, Davies, Michael A, Gershenwald, Jeffrey E, Stemke-Hale, Katherine, Rosenberg, Steven A, Margulies, Elliott H

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Novel somatic mutations in heterotrimeric G proteins in melanoma von Cárdenas-Navia, L. Isabel, Cruz, Pedro, Lin, Jimmy C., NISC Comparative Sequencing Program, Rosenberg, Steven A., Samuels, Yardena

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Delving into somatic variation in sporadic melanoma von Walia, Vijay, Mu, Euphemia W., Lin, Jimmy C., Samuels, Yardena

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Translational utility of next-generation sequencing von Ong, Frank S., Lin, Jimmy C., Das, Kingshuk, Grosu, Daniel S., Fan, Jian-Bing

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Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma von Samuels, Yardena, Palavalli, Lavanya H, Prickett, Todd D, Wunderlich, John R, Wei, Xiaomu, Burrell, Allison S, Porter-Gill, Patricia, Davis, Sean, Wang, Chenwei, Cronin, Julia C, Agrawal, Neena S, Lin, Jimmy C, Westbroek, Wendy, Hoogstraten-Miller, Shelley, Molinolo, Alfredo A, Fetsch, Patricia, Filie, Armando C, O'Connell, Michael P, Banister, Carolyn E, Howard, Jason D, Buckhaults, Phillip, Weeraratna, Ashani T, Brody, Lawrence C, Rosenberg, Steven A

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Core Clinical Data Elements for Cancer Genomic Repositories: A Multi-stakeholder Consensus von Conley, Robert B., Dickson, Dane, Zenklusen, Jean Claude, Al Naber, Jennifer, Messner, Donna A., Atasoy, Ajlan, Chaihorsky, Lena, Collyar, Deborah, Compton, Carolyn, Ferguson, Martin, Khozin, Sean, Klein, Roger D., Kotte, Sri, Kurzrock, Razelle, Lin, C. Jimmy, Liu, Frank, Marino, Ingrid, McDonough, Robert, McNeal, Amy, Miller, Vincent, Schilsky, Richard L., Wang, Lisa I.

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Mutational and Functional Analysis of the Tumor-Suppressor PTPRD in Human Melanoma von Walia, Vijay, Prickett, Todd D., Kim, Jung-Sik, Gartner, Jared J., Lin, Jimmy C., Zhou, Ming, Rosenberg, Steven A., Elble, Randolph C., Solomon, David A., Waldman, Todd, Samuels, Yardena

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RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells von Qutob, Nouar, Masuho, Ikuo, Alon, Michal, Emmanuel, Rafi, Cohen, Isadora, Di Pizio, Antonella, Madore, Jason, Elkahloun, Abdel, Ziv, Tamar, Levy, Ronen, Gartner, Jared J., Hill, Victoria K., Lin, Jimmy C., Hevroni, Yael, Greenberg, Polina, Brodezki, Alexandra, Rosenberg, Steven A., Kosloff, Mickey, Hayward, Nicholas K., Admon, Arie, Niv, Masha Y., Scolyer, Richard A., Martemyanov, Kirill A., Samuels, Yardena

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