Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model von Rogers, Thomas F., Zhao, Fangzhu, Huang, Deli, Beutler, Nathan, Burns, Alison, He, Wan-Ting, Limbo, Oliver, Smith, Chloe, Song, Ge, Woehl, Jordan, Yang, Linlin, Abbott, Robert K., Callaghan, Sean, Garcia, Elijah, Hurtado, Jonathan, Parren, Mara, Peng, Linghang, Ramirez, Sydney, Ricketts, James, Ricciardi, Michael J., Rawlings, Stephen A., Wu, Nicholas C., Yuan, Meng, Smith, Davey M., Nemazee, David, Teijaro, John R., Voss, James E., Wilson, Ian A., Andrabi, Raiees, Briney, Bryan, Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R.

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Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks von Langerak, Petra, Mejia-Ramirez, Eva, Limbo, Oliver, Russell, Paul

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Mre11 complex links sister chromatids to promote repair of a collapsed replication fork von Zhu, Min, Zhao, Hongchang, Limbo, Oliver, Russell, Paul

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Mre11-Rad50-dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1 von Limbo, Oliver, Yamada, Yoshiki, Russell, Paul

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Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair von Williams, R. Scott, Dodson, Gerald E., Limbo, Oliver, Yamada, Yoshiki, Williams, Jessica S., Guenther, Grant, Classen, Scott, Glover, J.N. Mark, Iwasaki, Hiroshi, Russell, Paul, Tainer, John A.

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HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway von Krause, Robert, Snyman, Jumari, Shi-Hsia, Hwa, Muema, Daniel, Karim, Farina, Ganga, Yashica, Ngoepe, Abigail, Zungu, Yenzekile, Gazy, Inbal, Bernstein, Mallory, Khan, Khadija, Mazibuko, Matilda, Mthabela, Ntombifuthi, Ramjit, Dirhona, Limbo, Oliver, Jardine, Joseph, Sok, Devin, Wilson, Ian A, Hanekom, Willem, Sigal, Alex, Kløverpris, Henrik, Ndung'u, Thumbi, Leslie, Alasdair

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Critical Function of γH2A in S-Phase von Mejia-Ramirez, Eva, Limbo, Oliver, Langerak, Petra, Russell, Paul

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ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair von Williams, R Scott, Russell, Paul, Tainer, John A, Williams, Gareth J, Williams, Jessica S, Moncalian, Gabriel, Arvai, Andrew S, Limbo, Oliver, Guenther, Grant, SilDas, Soumita, Hammel, Michal

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Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast von Sanchez, Arancha, Gadaleta, Mariana C, Limbo, Oliver, Russell, Paul

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Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus von Zhao, Fangzhu, Berndsen, Zachary T., Pedreño-Lopez, Nuria, Burns, Alison, Allen, Joel D., Barman, Shawn, Lee, Wen-Hsin, Chakraborty, Srirupa, Gnanakaran, Sandrasegaram, Sewall, Leigh M., Ozorowski, Gabriel, Limbo, Oliver, Song, Ge, Yong, Peter, Callaghan, Sean, Coppola, Jessica, Weisgrau, Kim L., Lifson, Jeffrey D., Nedellec, Rebecca, Voigt, Thomas B., Laurino, Fernanda, Louw, Johan, Rosen, Brandon C., Ricciardi, Michael, Crispin, Max, Desrosiers, Ronald C., Rakasz, Eva G., Watkins, David I., Andrabi, Raiees, Ward, Andrew B., Burton, Dennis R., Sok, Devin

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Tonoplast-localized Abc2 Transporter Mediates Phytochelatin Accumulation in Vacuoles and Confers Cadmium Tolerance von Mendoza-Cózatl, David G., Zhai, Zhiyang, Jobe, Timothy O., Akmakjian, Garo Z., Song, Won-Yong, Limbo, Oliver, Russell, Matthew R., Kozlovskyy, Volodymyr I., Martinoia, Enrico, Vatamaniuk, Olena K., Russell, Paul, Schroeder, Julian I.

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Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast von Cavero, Santiago, Limbo, Oliver, Russell, Paul

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Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways von Zhao, Fangzhu, Keating, Celina, Ozorowski, Gabriel, Shaabani, Namir, Francino-Urdaniz, Irene M., Barman, Shawn, Limbo, Oliver, Burns, Alison, Zhou, Panpan, Ricciardi, Michael J., Woehl, Jordan, Tran, Quoc, Turner, Hannah L., Peng, Linghang, Huang, Deli, Nemazee, David, Andrabi, Raiees, Sok, Devin, Teijaro, John R., Whitehead, Timothy A., Ward, Andrew B., Burton, Dennis R., Jardine, Joseph G.

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Phosphorylation-regulated binding of Ctp1 to Nbs1 is critical for repair of DNA double-strand breaks von Dodson, Gerald E., Limbo, Oliver, Nieto, Devon, Russell, Paul

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RNase H eliminates R‐loops that disrupt DNA replication but is nonessential for efficient DSB repair von Zhao, Hongchang, Zhu, Min, Limbo, Oliver, Russell, Paul

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Tolerance of Deregulated G1/S Transcription Depends on Critical G1/S Regulon Genes to Prevent Catastrophic Genome Instability von Caetano, Catia, Limbo, Oliver, Farmer, Sarah, Klier, Steffi, Dovey, Claire, Russell, Paul, de Bruin, Robertus Antonius Maria

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BRCT Domain Interactions with Phospho-Histone H2A Target Crb2 to Chromatin at Double-Strand Breaks and Maintain the DNA Damage Checkpoint von Sofueva, Sevil, Du, Li-Lin, Limbo, Oliver, Williams, Jessica S., Russell, Paul

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Regulation of the Rhp26ᴱᴿCC⁶/CSᴮ chromatin remodeler by a novel conserved leucine latch motif von Wang, Lanfeng, Limbo, Oliver, Fei, Jia, Chen, Lu, Kim, Bong, Luo, Jie, Chong, Jenny, Conaway, Ronald C, Conaway, Joan W, Ranish, Jeff A, Kadonaga, James T, Russell, Paul, Wang, Dong

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Mre11 Nuclease Activity and Ctp1 Regulate Chk1 Activation by Rad3ATR and Tel1ATM Checkpoint Kinases at Double-Strand Breaks von Limbo, Oliver, Porter-Goff, Mary E., Rhind, Nicholas, Russell, Paul

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Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease von Zhou, Panpan, Song, Ge, Liu, Hejun, Yuan, Meng, He, Wan-ting, Beutler, Nathan, Zhu, Xueyong, Tse, Longping V., Martinez, David R., Schäfer, Alexandra, Anzanello, Fabio, Yong, Peter, Peng, Linghang, Dueker, Katharina, Musharrafieh, Rami, Callaghan, Sean, Capozzola, Tazio, Limbo, Oliver, Parren, Mara, Garcia, Elijah, Rawlings, Stephen A., Smith, Davey M., Nemazee, David, Jardine, Joseph G., Safonova, Yana, Briney, Bryan, Rogers, Thomas F., Wilson, Ian A., Baric, Ralph S., Gralinski, Lisa E., Burton, Dennis R., Andrabi, Raiees

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