Biochemical Alterations During Storage of Human Blood from Male and Female Donors von DeVenuto, F., Wilson, H. L., Wilson, S. S., Ligon, D. F.

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Human erythrocyte membrane uptake of progesterone and chemical alterations von Devenuto, Frank, Ligon, Dorothy F., Friedrichsen, Don H., Wilson, Harold L.

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Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02 von Wen, Patrick Y, Chang, Susan M, Lamborn, Kathleen R, Kuhn, John G, Norden, Andrew D, Cloughesy, Timothy F, Robins, H Ian, Lieberman, Frank S, Gilbert, Mark R, Mehta, Minesh P, Drappatz, Jan, Groves, Morris D, Santagata, Sandro, Ligon, Azra H, Yung, W K Alfred, Wright, John J, Dancey, Janet, Aldape, Kenneth D, Prados, Michael D, Ligon, Keith L

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Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations von Poduri, Annapurna, Evrony, Gilad D., Cai, Xuyu, Elhosary, Princess Christina, Beroukhim, Rameen, Lehtinen, Maria K., Hills, L. Benjamin, Heinzen, Erin L., Hill, Anthony, Hill, R. Sean, Barry, Brenda J., Bourgeois, Blaise F.D., Riviello, James J., Barkovich, A. James, Black, Peter M., Ligon, Keith L., Walsh, Christopher A.

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Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma von Abedalthagafi, Malak, Bi, Wenya Linda, Aizer, Ayal A, Merrill, Parker H, Brewster, Ryan, Agarwalla, Pankaj K, Listewnik, Marc L, Dias-Santagata, Dora, Thorner, Aaron R, Van Hummelen, Paul, Brastianos, Priscilla K, Reardon, David A, Wen, Patrick Y, Al-Mefty, Ossama, Ramkissoon, Shakti H, Folkerth, Rebecca D, Ligon, Keith L, Ligon, Azra H, Alexander, Brian M, Dunn, Ian F, Beroukhim, Rameen, Santagata, Sandro

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The Central Nervous System-Restricted Transcription Factor Olig2 Opposes p53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma von Mehta, Shwetal, Huillard, Emmanuelle, Kesari, Santosh, Maire, Cecile L., Golebiowski, Diane, Harrington, Emily P., Alberta, John A., Kane, Michael F., Theisen, Matthew, Ligon, Keith L., Rowitch, David H., Stiles, Charles D.

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Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations von Brastianos, Priscilla K, Horowitz, Peleg M, Santagata, Sandro, Jones, Robert T, McKenna, Aaron, Getz, Gad, Ligon, Keith L, Palescandolo, Emanuele, Van Hummelen, Paul, Ducar, Matthew D, Raza, Alina, Sunkavalli, Ashwini, MacConaill, Laura E, Stemmer-Rachamimov, Anat O, Louis, David N, Hahn, William C, Dunn, Ian F, Beroukhim, Rameen

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Toward precision medicine in glioblastoma: the promise and the challenges von Prados, Michael D, Byron, Sara A, Tran, Nhan L, Phillips, Joanna J, Molinaro, Annette M, Ligon, Keith L, Wen, Patrick Y, Kuhn, John G, Mellinghoff, Ingo K, de Groot, John F, Colman, Howard, Cloughesy, Timothy F, Chang, Susan M, Ryken, Timothy C, Tembe, Waibhav D, Kiefer, Jeffrey A, Berens, Michael E, Craig, David W, Carpten, John D, Trent, Jeffrey M

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Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods von Stevens, Michael, Cheng, Jeffrey B, Li, Daofeng, Xie, Mingchao, Hong, Chibo, Maire, Cécile L, Ligon, Keith L, Hirst, Martin, Marra, Marco A, Costello, Joseph F, Wang, Ting

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Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors von Ramkissoon, Shakti H, Bandopadhayay, Pratiti, Hwang, Jaeho, Ramkissoon, Lori A, Greenwald, Noah F, Schumacher, Steven E, O'Rourke, Ryan, Pinches, Nathan, Ho, Patricia, Malkin, Hayley, Sinai, Claire, Filbin, Mariella, Plant, Ashley, Bi, Wenya Linda, Chang, Michael S, Yang, Edward, Wright, Karen D, Manley, Peter E, Ducar, Matthew, Alexandrescu, Sanda, Lidov, Hart, Delalle, Ivana, Goumnerova, Liliana C, Church, Alanna J, Janeway, Katherine A, Harris, Marian H, MacConaill, Laura E, Folkerth, Rebecca D, Lindeman, Neal I, Stiles, Charles D, Kieran, Mark W, Ligon, Azra H, Santagata, Sandro, Dubuc, Adrian M, Chi, Susan N, Beroukhim, Rameen, Ligon, Keith L

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Nivolumab in Patients With Relapsed or Refractory Hematologic Malignancy: Preliminary Results of a Phase Ib Study von Lesokhin, Alexander M, Ansell, Stephen M, Armand, Philippe, Scott, Emma C, Halwani, Ahmad, Gutierrez, Martin, Millenson, Michael M, Cohen, Adam D, Schuster, Stephen J, Lebovic, Daniel, Dhodapkar, Madhav, Avigan, David, Chapuy, Bjoern, Ligon, Azra H, Freeman, Gordon J, Rodig, Scott J, Cattry, Deepika, Zhu, Lili, Grosso, Joseph F, Bradley Garelik, M Brigid, Shipp, Margaret A, Borrello, Ivan, Timmerman, John

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Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model von Reardon, David A, Gokhale, Prafulla C, Klein, Sarah R, Ligon, Keith L, Rodig, Scott J, Ramkissoon, Shakti H, Jones, Kristen L, Conway, Amy Saur, Liao, Xiaoyun, Zhou, Jun, Wen, Patrick Y, Van Den Abbeele, Annick D, Hodi, F Stephen, Qin, Lei, Kohl, Nancy E, Sharpe, Arlene H, Dranoff, Glenn, Freeman, Gordon J

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Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial von Keskin, Derin B., Anandappa, Annabelle J., Sun, Jing, Tirosh, Itay, Mathewson, Nathan D., Li, Shuqiang, Oliveira, Giacomo, Giobbie-Hurder, Anita, Felt, Kristen, Gjini, Evisa, Shukla, Sachet A., Hu, Zhuting, Li, Letitia, Le, Phuong M., Allesøe, Rosa L., Richman, Alyssa R., Kowalczyk, Monika S., Abdelrahman, Sara, Geduldig, Jack E., Charbonneau, Sarah, Pelton, Kristine, Iorgulescu, J. Bryan, Elagina, Liudmila, Zhang, Wandi, Olive, Oriol, McCluskey, Christine, Olsen, Lars R., Stevens, Jonathan, Lane, William J., Salazar, Andres M., Daley, Heather, Wen, Patrick Y., Chiocca, E. Antonio, Harden, Maegan, Lennon, Niall J., Gabriel, Stacey, Getz, Gad, Lander, Eric S., Regev, Aviv, Ritz, Jerome, Neuberg, Donna, Rodig, Scott J., Ligon, Keith L., Suvà, Mario L., Wucherpfennig, Kai W., Hacohen, Nir, Fritsch, Edward F., Livak, Kenneth J., Ott, Patrick A., Wu, Catherine J., Reardon, David A.

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The Immunosuppressive Niche of Soft-Tissue Sarcomas is Sustained by Tumor-Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid Structures von Chen, Lingling, Oke, Teniola, Siegel, Nicholas, Cojocaru, Gady, Tam, Ada J, Blosser, Richard L, Swailes, Jessica, Ligon, John A, Lebid, Andriana, Morris, Carol, Levin, Adam, Rhee, Daniel S, Johnston, Fabian M, Greer, Jonathan B, Meyer, Christian F, Ladle, Brian H, Thompson, Elizabeth D, Montgomery, Elizabeth A, Choi, Woonyoung, McConkey, David J, Anders, Robert A, Pardoll, Drew M, Llosa, Nicolas J

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Atypical Spindle Cell Lipomatous Tumor: Clinicopathologic Characterization of 232 Cases Demonstrating a Morphologic Spectrum von Mariño-Enriquez, Adrian, Nascimento, Alessandra F, Ligon, Azra H, Liang, Cherwei, Fletcher, Christopher D.M

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Contemporary prognostic signatures and refined risk stratification of gliomas: An analysis of 4400 tumors von Ghosh, Hia S, Patel, Ruchit V, Woodward, Eleanor, Greenwald, Noah F, Bhave, Varun M, Maury, Eduardo A, Cello, Gregory, Hoffman, Samantha E, Li, Yvonne, Gupta, Hersh, Youssef, Gilbert, Spurr, Liam F, Vogelzang, Jayne, Touat, Mehdi, Dubois, Frank, Cherniack, Andrew D, Guo, Xiaopeng, Tavakol, Sherwin, Cioffi, Gino, Lindeman, Neal I, Ligon, Azra H, Chiocca, E Antonio, Reardon, David A, Wen, Patrick Y, Meredith, David M, Santagata, Sandro, Barnholtz-Sloan, Jill S, Ligon, Keith L, Beroukhim, Rameen, Bi, Wenya Linda

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A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma von Aizer, Ayal A, Abedalthagafi, Malak, Bi, Wenya Linda, Horvath, Margaret C, Arvold, Nils D, Al-Mefty, Ossama, Lee, Eudocia Q, Nayak, Lakshmi, Rinne, Mikael L, Norden, Andrew D, Reardon, David A, Wen, Patrick Y, Ligon, Keith L, Ligon, Azra H, Beroukhim, Rameen, Dunn, Ian F, Santagata, Sandro, Alexander, Brian M

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Quantification of aneuploidy in targeted sequencing data using ASCETS von Spurr, Liam F, Touat, Mehdi, Taylor, Alison M, Dubuc, Adrian M, Shih, Juliann, Meredith, David M, Pisano, William V, Meyerson, Matthew L, Ligon, Keith L, Cherniack, Andrew D, Li, Yvonne Y, Beroukhim, Rameen

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Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes von Ligon, John A, Choi, Woonyoung, Cojocaru, Gady, Fu, Wei, Hsiue, Emily Han-Chung, Oke, Teniola F, Siegel, Nicholas, Fong, Megan H, Ladle, Brian, Pratilas, Christine A, Morris, Carol D, Levin, Adam, Rhee, Daniel S, Meyer, Christian F, Tam, Ada J, Blosser, Richard, Thompson, Elizabeth D, Suru, Aditya, McConkey, David, Housseau, Franck, Anders, Robert, Pardoll, Drew M, Llosa, Nicolas

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Intermediate DNA methylation is a conserved signature of genome regulation von Elliott, GiNell, Hong, Chibo, Xing, Xiaoyun, Zhou, Xin, Li, Daofeng, Coarfa, Cristian, Bell, Robert J.A., Maire, Cecile L., Ligon, Keith L., Sigaroudinia, Mahvash, Gascard, Philippe, Tlsty, Thea D., Harris, R. Alan, Schalkwyk, Leonard C., Bilenky, Misha, Mill, Jonathan, Farnham, Peggy J., Kellis, Manolis, Marra, Marco A., Milosavljevic, Aleksandar, Hirst, Martin, Stormo, Gary D., Wang, Ting, Costello, Joseph F.

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