Anti-PD-1/PD-L1 therapy of human cancer: past, present, and future von Chen, Lieping, Han, Xue

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A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization von Sanmamed, Miguel F., Chen, Lieping

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Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer von SZNOL, Mario, LIEPING CHEN

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Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer--response von Sznol, Mario, Chen, Lieping

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Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes von Doroshow, Deborah B, Sanmamed, Miguel F, Hastings, Katherine, Politi, Katerina, Rimm, David L, Chen, Lieping, Melero, Ignacio, Schalper, Kurt A, Herbst, Roy S

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Inducible expression of B7-H1 (PD-L1) and its selective role in tumor site immune modulation von Sanmamed, Miguel F, Chen, Lieping

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Durable Cancer Regression Off-Treatment and Effective Reinduction Therapy with an Anti-PD-1 Antibody von LIPSON, Evan J, SHARFMAN, William H, PARDOLL, Drew M, BRAHMER, Julie R, TOPALIAN, Suzanne L, DRAKE, Charles G, WOLLNER, Ira, TAUBE, Janis M, ANDERS, Robert A, HAIYING XU, SHENG YAO, PONS, Alice, LIEPING CHEN

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Kupffer Cell Suppression of CD8+ T Cells in Human Hepatocellular Carcinoma Is Mediated by B7-H1/Programmed Death-1 Interactions von KE WU, KRYCZEK, Ilona, LIEPING CHEN, WEIPING ZOO, WELLING, Theodore H

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Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non-Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis von Datar, Ila, Sanmamed, Miguel F, Wang, Jun, Henick, Brian S, Choi, Jungmin, Badri, Ti, Dong, Weilai, Mani, Nikita, Toki, Maria, Mejías, Luis D, Lozano, Maria D, Perez-Gracia, Jose Luis, Velcheti, Vamsidhar, Hellmann, Matthew D, Gainor, Justin F, McEachern, Kristen, Jenkins, David, Syrigos, Konstantinos, Politi, Katerina, Gettinger, Scott, Rimm, David L, Herbst, Roy S, Melero, Ignacio, Chen, Lieping, Schalper, Kurt A

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Spatially Resolved and Quantitative Analysis of VISTA/PD-1H as a Novel Immunotherapy Target in Human Non-Small Cell Lung Cancer von Villarroel-Espindola, Franz, Yu, Xiaoqing, Datar, Ila, Mani, Nikita, Sanmamed, Miguel, Velcheti, Vamsidhar, Syrigos, Konstantinos, Toki, Maria, Zhao, Hongyu, Chen, Lieping, Herbst, Roy S, Schalper, Kurt A

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Differential Expression and Significance of PD-L1, IDO-1, and B7-H4 in Human Lung Cancer von Schalper, Kurt A, Carvajal-Hausdorf, Daniel, McLaughlin, Joseph, Altan, Mehmet, Velcheti, Vamsidhar, Gaule, Patricia, Sanmamed, Miguel F, Chen, Lieping, Herbst, Roy S, Rimm, David L

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Cutting edge: A monoclonal antibody specific for the programmed death-1 homolog prevents graft-versus-host disease in mouse models von Flies, Dallas B, Wang, Shengdian, Xu, Haiying, Chen, Lieping

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Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4 von Lu, Ning, Li, Ying, Zhang, Zhiqiang, Xing, Junji, Sun, Ying, Yao, Sheng, Chen, Lieping

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Evidence for a Role of the PD-1:PD-L1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell Carcinoma von LYFORD-PIKE, Sofia, SHIWEN PENG, LIEPING CHEN, DRAKE, Charles G, TOPALIAN, Suzanne L, PARDOLL, Drew M, PAI, Sara I, YOUNG, Geoffrey D, TAUBE, Janis M, WESTRA, William H, AKPENG, Belinda, BRUNO, Tullia C, RICHMON, Jeremy D, HAO WANG, BISHOP, Justin A

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Fine tuning the immune response through B7-H3 and B7-H4 von Yi, Kyung H, Chen, Lieping

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Targeting IL-21 to tumor-reactive T cells enhances memory T cell responses and anti-PD-1 antibody therapy von Li, Ying, Cong, Yanni, Jia, Mingming, He, Qianqian, Zhong, Haiqing, Zhao, Yun, Li, Hang, Yan, Meining, You, Jia, Liu, Jia, Chen, Lieping, Hang, Haiying, Wang, Shengdian

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Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer von Topalian, Suzanne L, Hodi, F. Stephen, Brahmer, Julie R, Gettinger, Scott N, Smith, David C, McDermott, David F, Powderly, John D, Carvajal, Richard D, Sosman, Jeffrey A, Atkins, Michael B, Leming, Philip D, Spigel, David R, Antonia, Scott J, Horn, Leora, Drake, Charles G, Pardoll, Drew M, Chen, Lieping, Sharfman, William H, Anders, Robert A, Taube, Janis M, McMiller, Tracee L, Xu, Haiying, Korman, Alan J, Jure-Kunkel, Maria, Agrawal, Shruti, McDonald, Daniel, Kollia, Georgia D, Gupta, Ashok, Wigginton, Jon M, Sznol, Mario

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Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7‐homolog 1‐dependent CD8+ T cell tolerance von Diehl, Linda, Schurich, Anna, Grochtmann, Regina, Hegenbarth, Silke, Chen, Lieping, Knolle, Percy A.

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B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells von Azuma, Takeshi, Yao, Sheng, Zhu, Gefeng, Flies, Andrew S., Flies, Sarah J., Chen, Lieping

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Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates von BRAHMER, Julie R, DRAKE, Charles G, GILSON, Marta M, CHANGYU WANG, SELBY, Mark, TAUBE, Janis M, ANDERS, Robert, LIEPING CHEN, KORMAN, Alan J, PARDOLL, Drew M, LOWY, Israel, TOPALIAN, Suzanne L, WOLLNER, Ira, POWDERLY, John D, PICUS, Joel, SHARFMAN, William H, STANKEVICH, Elizabeth, PONS, Alice, SALAY, Theresa M, MCMILLER, Tracee L

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