A New Contact Killing Toxin Permeabilizes Cells and Belongs to a Broadly Distributed Protein Family von Crisan, Cristian V, Chandrashekar, Harshini, Everly, Catherine, Steinbach, Gabi, Hill, Shannon E, Yunker, Peter J, Lieberman, Raquel R, Hammer, Brian K

Volltext

Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step von Bruce, Emily A, Huang, Meei-Li, Perchetti, Garrett A, Tighe, Scott, Laaguiby, Pheobe, Hoffman, Jessica J, Gerrard, Diana L, Nalla, Arun K, Wei, Yulun, Greninger, Alexander L, Diehl, Sean A, Shirley, David J, Leonard, Debra G B, Huston, Christopher D, Kirkpatrick, Beth D, Dragon, Julie A, Crothers, Jessica W, Jerome, Keith R, Botten, Jason W

Volltext

Amyloid accelerator polyphosphate fits as the mystery density in α-synuclein fibrils von Huettemann, Philipp, Mahadevan, Pavithra, Lempart, Justine, Tse, Eric, Dehury, Budheswar, Edwards, Brian F P, Southworth, Daniel R, Sahoo, Bikash R, Jakob, Ursula

Volltext

A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation von Smith, Christopher E, Tsai, Yien Che, Liang, Yu-He, Khago, Domarin, Mariano, Jennifer, Li, Jess, Tarasov, Sergey G, Gergel, Emma, Tsai, Borong, Villaneuva, Matthew, Clapp, Michelle E, Magidson, Valentin, Chari, Raj, Byrd, R Andrew, Ji, Xinhua, Weissman, Allan M

Volltext

Correlation between chemical denaturation and the unfolding energetics of Acanthamoeba actophorin von Thota, Nikhil, Quirk, Stephen, Zhuang, Yi, Stover, Erica R., Lieberman, Raquel L., Hernandez, Rigoberto

Volltext

Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane von Lieberman, Raquel L, Rosenzweig, Amy C

Volltext

Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability von Scelsi, Hailee F, Hill, Kamisha R, Barlow, Brett M, Martin, Mackenzie D, Lieberman, Raquel L

Volltext

Comparative Efficacy and Safety of Atypical and Conventional Antipsychotic Drugs in First-Episode Psychosis: A Randomized, Double-Blind Trial of Olanzapine Versus Haloperidol von Lieberman, Jeffrey A., Tollefson, Gary, Tohen, Mauricio, Green, Alan I., Gur, Raquel E., Kahn, Rene, McEvoy, Joseph, Perkins, Diana, Sharma, Tonmoy, Zipursky, Robert, Wei, Hank, Hamer, Robert M.

Volltext

Calcium dysregulation potentiates wild-type myocilin misfolding: implications for glaucoma pathogenesis von Saccuzzo, Emily G., Martin, Mackenzie D., Hill, Kamisha R., Ma, Minh Thu, Ku, Yemo, Lieberman, Raquel L.

Volltext

A blueprint for academic laboratories to produce SARS-CoV-2 quantitative RT-PCR test kits von Mascuch, Samantha J., Fakhretaha-Aval, Sara, Bowman, Jessica C., Ma, Minh Thu H., Thomas, Gwendell, Bommarius, Bettina, Ito, Chieri, Zhao, Liangjun, Newnam, Gary P., Matange, Kavita R., Thapa, Hem R., Barlow, Brett, Donegan, Rebecca K., Nguyen, Nguyet A., Saccuzzo, Emily G., Obianyor, Chiamaka T., Karunakaran, Suneesh C., Pollet, Pamela, Rothschild-Mancinelli, Brooke, Mestre-Fos, Santi, Guth-Metzler, Rebecca, Bryksin, Anton V., Petrov, Anton S., Hazell, Mallory, Ibberson, Carolyn B., Penev, Petar I., Mannino, Robert G., Lam, Wilbur A., Garcia, Andrés J., Kubanek, Julia, Agarwal, Vinayak, Hud, Nicholas V., Glass, Jennifer B., Williams, Loren Dean, Lieberman, Raquel L.

Volltext

Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma von Stothert, Andrew R., Suntharalingam, Amirthaa, Tang, Xiaolan, Crowley, Vincent M., Mishra, Sanket J., Webster, Jack M., Nordhues, Bryce A., Huard, Dustin J. E., Passaglia, Christopher L., Lieberman, Raquel L., Blagg, Brian S. J., Blair, Laura J., Koren, John, Dickey, Chad A.

Volltext

Biological Methane Oxidation: Regulation, Biochemistry, and Active Site Structure of Particulate Methane Monooxygenase von Lieberman, Raquel L., Rosenzweig, Amy C.

Volltext

E. coli Ribonucleotide Reductase β2 Subunit Inactivation by Triapine Occurs through Binding of a Triapine–Fe(II) Adduct von Safiarian, Mohammad S, Watson, R. Atlee, Lieberman, Raquel L, Barry, Bridgette A, Offenbacher, Adam R

Volltext

Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold von Crowley, Vincent M, Khandelwal, Anuj, Mishra, Sanket, Stothert, Andrew R, Huard, Dustin J. E, Zhao, Jinbo, Muth, Aaron, Duerfeldt, Adam S, Kizziah, James L, Lieberman, Raquel L, Dickey, Chad A, Blagg, Brian S. J

Volltext

Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication von Balistreri, Giuseppe, Viiliäinen, Johanna, Turunen, Mikko, Diaz, Raquel, Lyly, Lauri, Pekkonen, Pirita, Rantala, Juha, Ojala, Krista, Sarek, Grzegorz, Teesalu, Mari, Denisova, Oxana, Peltonen, Karita, Julkunen, Ilkka, Varjosalo, Markku, Kainov, Denis, Kallioniemi, Olli, Laiho, Marikki, Taipale, Jussi, Hautaniemi, Sampsa, Ojala, Päivi M

Volltext

Recombinant antibodies recognize conformation-dependent epitopes of the leucine zipper of misfolding-prone myocilin von Patterson-Orazem, Athéna C., Qerqez, Ahlam N., Azouz, Laura R., Ma, Minh Thu, Hill, Shannon E., Ku, Yemo, Schildmeyer, Lisa A., Maynard, Jennifer A., Lieberman, Raquel L.

Volltext

Consensus recommendations for trabecular meshwork cell isolation, characterization and culture von Keller, Kate E., Bhattacharya, Sanjoy K., Borrás, Theresa, Brunner, Thomas M., Chansangpetch, Sunee, Clark, Abbott F., Dismuke, W. Michael, Du, Yiqin, Elliott, Michael H., Ethier, C. Ross, Faralli, Jennifer A., Freddo, Thomas F., Fuchshofer, Rudolf, Giovingo, Michael, Gong, Haiyan, Gonzalez, Pedro, Huang, Alex, Johnstone, Murray A., Kaufman, Paul L., Kelley, Mary J., Knepper, Paul A., Kopczynski, Casey C., Kuchtey, John G., Kuchtey, Rachel W., Kuehn, Markus H., Lieberman, Raquel L., Lin, Shan C., Liton, Paloma, Liu, Yutao, Lütjen-Drecoll, Elke, Mao, Weiming, Masis-Solano, Marisse, McDonnell, Fiona, McDowell, Colleen M., Overby, Darryl R., Pattabiraman, Padmanabhan P., Raghunathan, Vijay K., Rao, P. Vasanth, Rhee, Douglas J., Chowdhury, Uttio Roy, Russell, Paul, Samples, John R., Schwartz, Donald, Stubbs, Evan B., Tamm, Ernst R., Tan, James C., Toris, Carol B., Torrejon, Karen Y., Vranka, Janice A., Wirtz, Mary K., Yorio, Thomas, Zhang, Jie, Zode, Gulab S., Fautsch, Michael P., Peters, Donna M., Acott, Ted S., Stamer, W. Daniel

Volltext

Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma von Stothert, Andrew R, Suntharalingam, Amirthaa, Huard, Dustin J E, Fontaine, Sarah N, Crowley, Vincent M, Mishra, Sanket, Blagg, Brian S J, Lieberman, Raquel L, Dickey, Chad A

Volltext

Purified Particulate Methane Monooxygenase from Methylococcus capsulatus (Bath) Is a Dimer with Both Mononuclear Copper and a Copper-Containing Cluster von Lieberman, Raquel L., Shrestha, Deepak B., Doan, Peter E., Hoffman, Brian M., Stemmler, Timothy L., Rosenzweig, Amy C.

Volltext

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase von Landon, Melissa R., Lieberman, Raquel L., Hoang, Quyen Q., Ju, Shulin, Caaveiro, Jose M. M., Orwig, Susan D., Kozakov, Dima, Brenke, Ryan, Chuang, Gwo-Yu, Beglov, Dmitry, Vajda, Sandor, Petsko, Gregory A., Ringe, Dagmar

Volltext