Chromothripsis in cancer cells: An update von Rode, Agata, Maass, Kendra Korinna, Willmund, Karolin Viktoria, Lichter, Peter, Ernst, Aurélie

Volltext

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas von Bender, Sebastian, Tang, Yujie, Lindroth, Anders M., Hovestadt, Volker, Jones, David T.W., Kool, Marcel, Zapatka, Marc, Northcott, Paul A., Sturm, Dominik, Wang, Wei, Radlwimmer, Bernhard, Højfeldt, Jonas W., Truffaux, Nathalène, Castel, David, Schubert, Simone, Ryzhova, Marina, Şeker-Cin, Huriye, Gronych, Jan, Johann, Pascal David, Stark, Sebastian, Meyer, Jochen, Milde, Till, Schuhmann, Martin, Ebinger, Martin, Monoranu, Camelia-Maria, Ponnuswami, Anitha, Chen, Spenser, Jones, Chris, Witt, Olaf, Collins, V. Peter, von Deimling, Andreas, Jabado, Nada, Puget, Stephanie, Grill, Jacques, Helin, Kristian, Korshunov, Andrey, Lichter, Peter, Monje, Michelle, Plass, Christoph, Cho, Yoon-Jae, Pfister, Stefan M.

Volltext

Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis von Körber, Verena, Yang, Jing, Barah, Pankaj, Wu, Yonghe, Stichel, Damian, Gu, Zuguang, Fletcher, Michael Nai Chung, Jones, David, Hentschel, Bettina, Lamszus, Katrin, Tonn, Jörg Christian, Schackert, Gabriele, Sabel, Michael, Felsberg, Jörg, Zacher, Angela, Kaulich, Kerstin, Hübschmann, Daniel, Herold-Mende, Christel, von Deimling, Andreas, Weller, Michael, Radlwimmer, Bernhard, Schlesner, Matthias, Reifenberger, Guido, Höfer, Thomas, Lichter, Peter

Volltext

Time-resolved, integrated analysis of clonally evolving genomes von Legrand, Carine, Andriantsoa, Ranja, Lichter, Peter, Raddatz, Günter, Lyko, Frank

Volltext

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia von Oakes, Christopher C, Seifert, Marc, Assenov, Yassen, Gu, Lei, Przekopowitz, Martina, Ruppert, Amy S, Wang, Qi, Imbusch, Charles D, Serva, Andrius, Koser, Sandra D, Brocks, David, Lipka, Daniel B, Bogatyrova, Olga, Weichenhan, Dieter, Brors, Benedikt, Rassenti, Laura, Kipps, Thomas J, Mertens, Daniel, Zapatka, Marc, Lichter, Peter, Döhner, Hartmut, Küppers, Ralf, Zenz, Thorsten, Stilgenbauer, Stephan, Byrd, John C, Plass, Christoph

Volltext

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing von Hovestadt, Volker, Jones, David T. W., Picelli, Simone, Wang, Wei, Kool, Marcel, Northcott, Paul A., Sultan, Marc, Stachurski, Katharina, Ryzhova, Marina, Warnatz, Hans-Jörg, Ralser, Meryem, Brun, Sonja, Bunt, Jens, Jäger, Natalie, Kleinheinz, Kortine, Erkek, Serap, Weber, Ursula D., Bartholomae, Cynthia C., von Kalle, Christof, Lawerenz, Chris, Eils, Jürgen, Koster, Jan, Versteeg, Rogier, Milde, Till, Witt, Olaf, Schmidt, Sabine, Wolf, Stephan, Pietsch, Torsten, Rutkowski, Stefan, Scheurlen, Wolfram, Taylor, Michael D., Brors, Benedikt, Felsberg, Jörg, Reifenberger, Guido, Borkhardt, Arndt, Lehrach, Hans, Wechsler-Reya, Robert J., Eils, Roland, Yaspo, Marie-Laure, Landgraf, Pablo, Korshunov, Andrey, Zapatka, Marc, Radlwimmer, Bernhard, Pfister, Stefan M., Lichter, Peter

Volltext

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas von Khuong-Quang, Dong-Anh, Buczkowicz, Pawel, Rakopoulos, Patricia, Liu, Xiao-Yang, Fontebasso, Adam M., Bouffet, Eric, Bartels, Ute, Albrecht, Steffen, Schwartzentruber, Jeremy, Letourneau, Louis, Bourgey, Mathieu, Bourque, Guillaume, Montpetit, Alexandre, Bourret, Genevieve, Lepage, Pierre, Fleming, Adam, Lichter, Peter, Kool, Marcel, von Deimling, Andreas, Sturm, Dominik, Korshunov, Andrey, Faury, Damien, Jones, David T., Majewski, Jacek, Pfister, Stefan M., Jabado, Nada, Hawkins, Cynthia

Volltext

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas von Kool, Marcel, Korshunov, Andrey, Remke, Marc, Jones, David T. W., Schlanstein, Maria, Northcott, Paul A., Cho, Yoon-Jae, Koster, Jan, Schouten-van Meeteren, Antoinette, van Vuurden, Dannis, Clifford, Steven C., Pietsch, Torsten, von Bueren, Andre O., Rutkowski, Stefan, McCabe, Martin, Collins, V. Peter, Bäcklund, Magnus L., Haberler, Christine, Bourdeaut, Franck, Delattre, Olivier, Doz, Francois, Ellison, David W., Gilbertson, Richard J., Pomeroy, Scott L., Taylor, Michael D., Lichter, Peter, Pfister, Stefan M.

Volltext

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype von Wu, Yonghe, Fletcher, Michael, Gu, Zuguang, Wang, Qi, Costa, Barbara, Bertoni, Anna, Man, Ka-Hou, Schlotter, Magdalena, Felsberg, Jörg, Mangei, Jasmin, Barbus, Martje, Gaupel, Ann-Christin, Wang, Wei, Weiss, Tobias, Eils, Roland, Weller, Michael, Liu, Haikun, Reifenberger, Guido, Korshunov, Andrey, Angel, Peter, Lichter, Peter, Herrmann, Carl, Radlwimmer, Bernhard

Volltext

miRNA-130a Targets ATG2B and DICER1 to Inhibit Autophagy and Trigger Killing of Chronic Lymphocytic Leukemia Cells von KOVALEVA, Valentina, MORA, Rodrigo, SEIFFERT, Martina, YOON JUNG PARK, PLASS, Christoph, CHIRAMEL, Abhilash I, BARTENSCHLAGER, Ralf, DÖHNER, Hartmut, STILGENBAUER, Stephan, PSCHERER, Armin, LICHTER, Peter

Volltext

Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data von Becker, Natalia, Toedt, Grischa, Lichter, Peter, Benner, Axel

Volltext

MAPK pathway activation in pilocytic astrocytoma von Jones, David T. W., Gronych, Jan, Lichter, Peter, Witt, Olaf, Pfister, Stefan M.

Volltext

Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients von ZEPPERNICK, Felix, AHMADI, Rezvan, CAMPOS, Benito, DICTUS, Christine, HELMKE, Burkhard M, BECKER, Natalia, LICHTER, Peter, UNTERBERG, Andreas, RADLWIMMER, Bernhard, HEROLD-MENDE, Christel C

Volltext

TelomereHunter - in silico estimation of telomere content and composition from cancer genomes von Feuerbach, Lars, Sieverling, Lina, Deeg, Katharina I, Ginsbach, Philip, Hutter, Barbara, Buchhalter, Ivo, Northcott, Paul A, Mughal, Sadaf S, Chudasama, Priya, Glimm, Hanno, Scholl, Claudia, Lichter, Peter, Fröhling, Stefan, Pfister, Stefan M, Jones, David T W, Rippe, Karsten, Brors, Benedikt

Volltext

Macromolecular crowding and its potential impact on nuclear function von Richter, Karsten, Nessling, Michelle, Lichter, Peter

Volltext

Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors von Ratnaparkhe, Manasi, Wong, John K. L., Wei, Pei-Chi, Hlevnjak, Mario, Kolb, Thorsten, Simovic, Milena, Haag, Daniel, Paul, Yashna, Devens, Frauke, Northcott, Paul, Jones, David T. W., Kool, Marcel, Jauch, Anna, Pastorczak, Agata, Mlynarski, Wojciech, Korshunov, Andrey, Kumar, Rajiv, Downing, Susanna M., Pfister, Stefan M., Zapatka, Marc, McKinnon, Peter J., Alt, Frederick W., Lichter, Peter, Ernst, Aurélie

Volltext

The need for a worldwide consensus for cell line authentication: Experience implementing a mandatory requirement at the International Journal of Cancer von Fusenig, Norbert E, Capes-Davis, Amanda, Bianchini, Franca, Sundell, Sherryl, Lichter, Peter

Volltext

Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme von Feng, Weijun, Kawauchi, Daisuke, Körkel-Qu, Huiqin, Deng, Huan, Serger, Elisabeth, Sieber, Laura, Lieberman, Jenna Ariel, Jimeno-González, Silvia, Lambo, Sander, Hanna, Bola S., Harim, Yassin, Jansen, Malin, Neuerburg, Anna, Friesen, Olga, Zuckermann, Marc, Rajendran, Vijayanad, Gronych, Jan, Ayrault, Olivier, Korshunov, Andrey, Jones, David T. W., Kool, Marcel, Northcott, Paul A., Lichter, Peter, Cortés-Ledesma, Felipe, Pfister, Stefan M., Liu, Hai-Kun

Volltext

Targeting Self-Renewal in High-Grade Brain Tumors Leads to Loss of Brain Tumor Stem Cells and Prolonged Survival von Zhu, Zhe, Khan, Muhammad Amir, Weiler, Markus, Blaes, Jonas, Jestaedt, Leonie, Geibert, Madeleine, Zou, Peng, Gronych, Jan, Bernhardt, Olga, Korshunov, Andrey, Bugner, Verena, Lichter, Peter, Radlwimmer, Bernhard, Heiland, Sabine, Bendszus, Martin, Wick, Wolfgang, Liu, Hai-Kun

Volltext

Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma von Witt, Hendrik, Mack, Stephen C., Ryzhova, Marina, Bender, Sebastian, Sill, Martin, Isserlin, Ruth, Benner, Axel, Hielscher, Thomas, Milde, Till, Remke, Marc, Jones, David T.W., Northcott, Paul A., Garzia, Livia, Bertrand, Kelsey C., Wittmann, Andrea, Yao, Yuan, Roberts, Stephen S., Massimi, Luca, Van Meter, Tim, Weiss, William A., Gupta, Nalin, Grajkowska, Wiesia, Lach, Boleslaw, Cho, Yoon-Jae, von Deimling, Andreas, Kulozik, Andreas E., Witt, Olaf, Bader, Gary D., Hawkins, Cynthia E., Tabori, Uri, Guha, Abhijit, Rutka, James T., Lichter, Peter, Korshunov, Andrey, Taylor, Michael D., Pfister, Stefan M.

Volltext