BACE inhibitor treatment of mice induces hyperactivity in a Seizure-related gene 6 family dependent manner without altering learning and memory von Nash, A., Gijsen, H. J. M., Hrupka, B. J., Teng, K. S.-L., Lichtenthaler, S. F., Takeshima, H., Gunnersen, J. M., Munro, K. M.

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Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage von Yang, C.Y., Chanalaris, A., Bonelli, S., McClurg, O., Hiles, G. Lorenzatti, Cates, A.L., Zarebska, J. Miotla, Vincent, T.L., Day, M.L., Müller, S.A., Lichtenthaler, S.F., Nagase, H., Scilabra, S.D., Troeberg, L.

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F-spondin regulates neuronal survival through activation of disabled-1 in the chicken ciliary ganglion von Peterziel, H., Sackmann, T., Strelau, J., Kuhn, P.H., Lichtenthaler, S.F., Marom, K., Klar, A., Unsicker, K.

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Mechanism of the Cleavage Specificity of Alzheimer's Disease γ -secretase Identified by Phenylalanine-Scanning Mutagenesis of the Transmembrane Domain of the Amyloid Precursor Prot... von Lichtenthaler, Stefan F., Wang, Rong, Grimm, Heike, Uljon, Sacha N., Masters, Colin L., Beyreuther, Konrad

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Alzheimer's disease : Correlation of the suppression of β-amyloid Peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome von CHRISTIE, G, MARKWELL, R. E, WARD, R. V, HOWLETT, D. R, HARTMANN, T, LICHTENTHALER, S. F, BEYREUTHER, K, UNDERWOOD, J, GRIBBLE, S. K, CAPPAI, R, MASTERS, C. L, TAMAOKA, A, GRAY, C. W, GARDNER, R. L, RIVETT, A. J, KARRAN, E. H, ALLSOP, D, SMITH, L, GODFREY, F, MANSFIELD, F, WADSWORTH, H, KING, R, MCLAUGHLIN, M, COOPER, D. G

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Bepridil and Amiodarone Simultaneously Target the Alzheimer's Disease  - and  -Secretase via Distinct Mechanisms von Mitterreiter, S., Page, R. M., Kamp, F., Hopson, J., Winkler, E., Ha, H.-R., Hamid, R., Herms, J., Mayer, T. U., Nelson, D. J., Steiner, H., Stahl, T., Zeitschel, U., Rossner, S., Haass, C., Lichtenthaler, S. F.

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A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease patients from controls von Pesämaa, Ida, Müller, Stephan A, Robinson, Sophie, Darcher, Alana, Paquet, Dominik, Zetterberg, Henrik, Lichtenthaler, Stefan F, Haass, Christian

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The Intramembrane Cleavage Site of the Amyloid Precursor Protein Depends on the Length of Its Transmembrane Domain von Lichtenthaler, Stefan F., Beher, Dirk, Grimm, Heike S., Wang, Rong, Shearman, Mark S., Masters, Colin L., Beyreuther, Konrad

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The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation von De la Vega, María Pagnon, Giedraitis, Vilmantas, Michno, Wojciech, Kilander, Lena, Güner, Gökhan, Zielinski, Mara, Löwenmark, Malin, Brundin, Rose Marie, Danfors, Torsten, Söderberg, Linda, Alafuzoff, Irina, Nilsson, Lars, Erlandsson, Anna, Willbold, Dieter, Müller, Stephan A, Schröder, Gunnar F, Hanrieder, Jörg, Lichtenthaler, Stefan F, Lannfelt, Lars, Sehlin, Dag, Ingelsson, Martin

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The Transmembrane Domain of the Amyloid Precursor Protein in Microsomal Membranes Is on Both Sides Shorter than Predicted von Grziwa, Beate, Grimm, Marcus O W, Masters, Colin L, Beyreuther, Konrad, Hartmann, Tobias, Lichtenthaler, Stefan F

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gamma-Secretase cleavage site specificity differs for intracellular and secretory amyloid beta von Grimm, Heike S, Beher, Dirk, Lichtenthaler, Stefan F, Shearman, Mark S, Beyreuther, Konrad, Hartmann, Tobias

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γ-secretase directly sheds the survival receptor BCMA from plasma cells von Laurent, Sarah A., Hoffmann, Franziska S., Kuhn, Peer-Hendrik, Cheng, Qingyu, Chu, Yuanyuan, Schmidt-Supprian, Marc, Hauck, Stefanie M., Schuh, Elisabeth, Krumbholz, Markus, Rübsamen, Heike, Wanngren, Johanna, Khademi, Mohsen, Olsson, Tomas, Alexander, Tobias, Hiepe, Falk, Pfister, Hans-Walter, Weber, Frank, Jenne, Dieter, Wekerle, Hartmut, Hohlfeld, Reinhard, Lichtenthaler, Stefan F., Meinl, Edgar

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Mutations in the Transmembrane Domain of APP Altering γ-Secretase Specificity von Lichtenthaler, Stefan F., Ida, Nobuo, Multhaup, Gerd, Masters, Colin L., Beyreuther, Konrad

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A novel substrate for analyzing Alzheimer’s disease γ-secretase von Lichtenthaler, Stefan F., Multhaup, Gerd, Masters, Colin L., Beyreuther, Konrad

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The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity von Hoffmann, Franziska S, Kuhn, Peer-Hendrik, Laurent, Sarah A, Hauck, Stefanie M, Berer, Kerstin, Wendlinger, Simone A, Krumbholz, Markus, Khademi, Mohsen, Olsson, Tomas, Dreyling, Martin, Pfister, Hans-Walter, Alexander, Tobias, Hiepe, Falk, Kümpfel, Tania, Crawford, Howard C, Wekerle, Hartmut, Hohlfeld, Reinhard, Lichtenthaler, Stefan F, Meinl, Edgar

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Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1 von Rudan Njavro, Jasenka, Klotz, Jakob, Dislich, Bastian, Wanngren, Johanna, Shmueli, Merav D., Herber, Julia, Kuhn, Peer‐Hendrik, Kumar, Rohit, Koeglsperger, Thomas, Conrad, Marcus, Wurst, Wolfgang, Feederle, Regina, Vlachos, Andreas, Michalakis, Stylianos, Jedlicka, Peter, Müller, Stephan A., Lichtenthaler, Stefan F.

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The Cell Adhesion Protein P-selectin Glycoprotein Ligand-1 Is a Substrate for the Aspartyl Protease BACE1 von Lichtenthaler, Stefan F., Dominguez, Diana-ines, Westmeyer, Gil G., Reiss, Karina, Haass, Christian, Saftig, Paul, De Strooper, Bart, Seed, Brian

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Amyloid at the cutting edge: activation of α-secretase prevents amyloidogenesis in an Alzheimer disease mouse model von Lichtenthaler, Stefan F., Haass, Christian

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Dimerization of β-Site β-Amyloid Precursor Protein-cleaving Enzyme von Westmeyer, Gil G., Willem, Michael, Lichtenthaler, Stefan F., Lurman, Glenn, Multhaup, Gerd, Assfalg-Machleidt, Irmgard, Reiss, Karina, Saftig, Paul, Haass, Christian

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Expression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region von Lammich, Sven, Schöbel, Susanne, Zimmer, Ann-Katrin, Lichtenthaler, Stefan F, Haass, Christian

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