Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor von Wu, Tingyu, Chen, Wei, Zhong, Yongwang, Hou, Xiaodan, Fang, Shengyun, Liu, Chen-Ying, Wang, Guanghui, Yu, Tong, Huang, Yu-Yang, Ouyang, Xuesong, Li, Henry Q X, Cui, Long, Yang, Yili

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Abstract 1051: Mutation detection in patient-derived xenografts by WES and RNAseq von Qian, Wubin, Li, Henry Q.X., Guo, Sheng

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Enforced expression of Runx3 improved CAR-T cell potency in solid tumor via enhancing resistance to activation-induced cell death von Wang, Yi, Zhang, Honghong, Du, Guoxiu, Luo, Hong, Su, Jingwen, Sun, Yansha, Zhou, Min, Shi, Bizhi, Li, Henry Q.X., Jiang, Hua, Li, Zonghai

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Abstract 1809: In vitro and in vivo characterization of human CD3EDG triple knock-in mice (CD3EDG HuGEMM™) for CD3 bispecific antibody evaluation von He, Daniel X., Zheng, Lei, Qian, Tianyi, An, Annie X., Li, Henry Q.x., Ouyang, Davy Xuesong

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Abstract 1810: Anti-human TNFR2 antagonist induces T cell proliferation and restores T cell balance to promote tumor killing in TNFR2 HuGEMM™ engrafted with MC38/OVA tumor cells von He, Daniel X., Zheng, Lei, Sun, Ruilin, An, Annie X., Li, Henry Q.x., Ouyang, Davy Xuesong

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Abstract 2947: Establishment and characterization of a series of murine cancer homograft models derived from induced cancer stem cells (iCSCs) von Wang, Jessie J., Zhang, Likun, An, Annie X., Li, Henry Q.X., Ouyang, Davy Xuesong

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Abstract 529: Characterization of a humanized TLR8 mouse model and its application in immuno-oncology drug development von Zhang, Hongjuan, Sun, Ruilin, An, Annie X., Li, Henry Q.x, Ouyang, Davy Xuesong

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Abstract 2948: The impact of drinking water pH on anti-PD-1 efficacy in syngeneic mouse models von Jin, Ying, Mu, Guangmao, Li, Fengge, Zhou, Huajun, An, Annie X., Chen, Bonnie X., Li, Henry Q.x, Ouyang, Davy Xuesong

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Abstract 1808: Tracing T cell activation cytokines in reporter models by bioluminescent imaging von Jin, Ying, Lian, Kaixia, Li, Fengge, Sun, Ruilin, An, Annie X., Li, Henry Q.x., Ouyang, Davy Xuesong

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Abstract 3005: Establishment and characterization of a series of lymphoma PDX models representing varied clinical behaviors and treatment responses von Wang, Jessie J., Song, Yanrui, Zheng, Jitai, Wu, Guiqing, Zhang, Likun, Li, Henry Q.X., Ouyang, Davy Xuesong

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Abstract 3115: Establishment and characterization of patient-derived breast cancer models for cancer studies von Chen, Leilei, Yang, Xueying, Zhang, Likun, Chen, Xiaobo, Li, Henry Q.X., Wang, Jingjing

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Abstract 4221: Characterization of OVA-expressing immunogenic syngeneic tumor models for immune checkpoint inhibitor evaluation von Nie, Chenpan, Zhang, Yi, Zheng, Jia, An, Annie X., Zhou, Jun, Li, Henry Q.X., Wang, Jingjing

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Abstract 617: MEK inhibitor rescued the efficacy of PD-1 blocker in STK11/LKB1 mutated colorectal cancer model von Liu, Demi X., Zhou, Jun, Nie, Chenpan, An, Annie X., Li, Henry Q.X., Wang, Jingjing

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Abstract 1322: Autocrine c-met/HGF HCC patient derived xenograft (PDX) models for evaluating c-met inhibitors von Chen, Dawei, Song, Xiaoming, Cai, Jie, Chen, Taiping, Chen, Yiyou, Li, Henry Q.X.

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Abstract 2344: PDX from the naïve NSCLC patients containing activating EGFR mutations are resistant to erlotinib but sensitive to c-met inhibitor von Yang, Mengmeng, Deng, Jiangyun, Song, Xiaoming, Cai, Jie, Chen, Taiping, Chen, Yiyou, Li, Henry Q.X.

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