P2.01-65 Temporal Changes of Radiation-Induced Lung Injury Following Proton Therapy for Non-Small Cell Lung Cancer (NSCLC) von Roshkovan, L., Lozano, A., Hanlon, A., Jain, V., Cengel, K., Li, C. Simone, Berman, A., Feigenberg, S., Katz, S.

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MA05.10 Pembrolizumab in the Treatment of Patients with Malignant Pleural Mesothelioma Following Progression After Initial Chemotherapy von Cengel, K., Katz, S., Roshkovan, L., Mcnulty, S., Lian, J., Aleynick, D., Culligan, M., Friedberg, J., Singhal, S., Li, C. Simone, Ciunci, C., Marmarelis, M., Alley, E., Langer, C.

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BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination von van Meijgaarden, Krista E., Li, Wenchao, Moorlag, Simone J. C. F. M., Koeken, Valerie A. C. M., Koenen, Hans J. P. M., Joosten, Leo A. B., Vyakarnam, Annapurna, Ahmed, Asma, Rakshit, Srabanti, Adiga, Vasista, Ottenhoff, Tom H. M., Li, Yang, Netea, Mihai G., Joosten, Simone A.

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BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity von Arts, Rob J.W., Moorlag, Simone J.C.F.M., Novakovic, Boris, Li, Yang, Wang, Shuang-Yin, Oosting, Marije, Kumar, Vinod, Xavier, Ramnik J., Wijmenga, Cisca, Joosten, Leo A.B., Reusken, Chantal B.E.M., Benn, Christine S., Aaby, Peter, Koopmans, Marion P., Stunnenberg, Hendrik G., van Crevel, Reinout, Netea, Mihai G.

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Global airborne sampling reveals a previously unobserved dimethyl sulfide oxidation mechanism in the marine atmosphere von Veres, Patrick R., Neuman, J. Andrew, Bertram, Timothy H., Assaf, Emmanuel, Wolfe, Glenn M., Williamson, Christina J., Weinzierl, Bernadett, Tilmes, Simone, Thompson, Chelsea R., Thames, Alexander B., Schroder, Jason C., Saiz-Lopez, Alfonso, Rollins, Andrew W., Roberts, James M., Price, Derek, Peischl, Jeff, Nault, Benjamin A., Møller, Kristian H., Miller, David O., Meinardi, Simone, Li, Qinyi, Lamarque, Jean-Francois, Kupc, Agnieszka, Kjaergaard, Henrik G., Kinnison, Douglas, Jimenez, Jose L., Jernigan, Christopher M., Hornbrook, Rebecca S., Hills, Alan, Dollner, Maximilian, Day, Douglas A., Cuevas, Carlos A., Campuzano-Jost, Pedro, Burkholder, James, Bui, T. Paul, Brune, William H., Brown, Steven S., Brock, Charles A., Bourgeois, Ilann, Blake, Donald R., Apel, Eric C., Ryerson, Thomas B.

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Recurrent activating mutations of CD28 in peripheral T-cell lymphomas von Rohr, J, Guo, S, Huo, J, Bouska, A, Lachel, C, Li, Y, Simone, P D, Zhang, W, Gong, Q, Wang, C, Cannon, A, Heavican, T, Mottok, A, Hung, S, Rosenwald, A, Gascoyne, R, Fu, K, Greiner, T C, Weisenburger, D D, Vose, J M, Staudt, L M, Xiao, W, Borgstahl, G E O, Davis, S, Steidl, C, McKeithan, T, Iqbal, J, Chan, W C

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Extensive transmission of microbes along the gastrointestinal tract von Schmidt, Thomas Sb, Hayward, Matthew R, Coelho, Luis P, Li, Simone S, Costea, Paul I, Voigt, Anita Y, Wirbel, Jakob, Maistrenko, Oleksandr M, Alves, Renato Jc, Bergsten, Emma, de Beaufort, Carine, Sobhani, Iradj, Heintz-Buschart, Anna, Sunagawa, Shinichi, Zeller, Georg, Wilmes, Paul, Bork, Peer

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Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes von Zhang, Bowen, Moorlag, Simone Jcfm, Dominguez-Andres, Jorge, Bulut, Özlem, Kilic, Gizem, Liu, Zhaoli, van Crevel, Reinout, Xu, Cheng-Jian, Joosten, Leo Ab, Netea, Mihai G, Li, Yang

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Effect of Pregabalin on Radiotherapy-Related Neuropathic Pain in Patients With Head and Neck Cancer: A Randomized Controlled Trial von Jiang, Jingru, Li, Yi, Shen, Qingyu, Rong, Xiaoming, Huang, Xiaolong, Li, Honghong, Zhou, Lizhi, Mai, Hai-Qiang, Zheng, Dong, Chen, Ming-Yuan, Xu, Yongteng, Li, Jibin, Hui, Xuan, Simone, 2nd, Charles B, Gaertner, Jan, Argyriou, Andreas A, Chow, Edward, Chen, Pingyan, Tang, Yamei

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Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease von Roe, James M., Vidal-Piñeiro, Didac, Sørensen, Øystein, Brandmaier, Andreas M., Düzel, Sandra, Gonzalez, Hector A., Kievit, Rogier A., Knights, Ethan, Kühn, Simone, Lindenberger, Ulman, Mowinckel, Athanasia M., Nyberg, Lars, Park, Denise C., Pudas, Sara, Rundle, Melissa M., Walhovd, Kristine B., Fjell, Anders M., Westerhausen, René

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Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination von Koeken, Valerie A. C. M, Qi, Cancan, Mourits, Vera P, de Bree, L. Charlotte J, Moorlag, Simone J. C. F. M, Sonawane, Vidhisha, Lemmers, Heidi, Dijkstra, Helga, Joosten, Leo A. B, van Laarhoven, Arjan, Xu, Cheng-Jian, van Crevel, Reinout, Netea, Mihai G, Li, Yang

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Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein von Keating, Samuel T., Groh, Laszlo, Thiem, Kathrin, Bekkering, Siroon, Li, Yang, Matzaraki, Vasiliki, van der Heijden, Charlotte D. C. C., van Puffelen, Jelmer H., Lachmandas, Ekta, Jansen, Trees, Oosting, Marije, de Bree, L. Charlotte J., Koeken, Valerie A. C. M., Moorlag, Simone J. C. F. M., Mourits, Vera P., van Diepen, Janna, Strienstra, Rinke, Novakovic, Boris, Stunnenberg, Hendrik G., van Crevel, Reinout, Joosten, Leo A. B., Netea, Mihai G., Riksen, Niels P.

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Predictors of functional outcome in patients with major depression and bipolar disorder: A dynamic network approach to identify distinct patterns of interacting symptoms von Platania, Giuseppe Alessio, Savia Guerrera, Claudia, Sarti, Pierfrancesco, Varrasi, Simone, Pirrone, Concetta, Popovic, Dina, Ventimiglia, Andrea, De Vivo, Simona, Cantarella, Rita Anna, Tascedda, Fabio, Drago, Filippo, Di Nuovo, Santo, Colliva, Chiara, Caraci, Filippo, Castellano, Sabrina, Blom, Johanna M C

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A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity von Li, Wenchao, Moorlag, Simone J.C.F.M., Koeken, Valerie A.C.M., Röring, Rutger J., de Bree, L. Charlotte J., Mourits, Vera P., Gupta, Manoj K., Zhang, Bowen, Fu, Jianbo, Zhang, Zhenhua, Grondman, Inge, van Meijgaarden, Krista E., Zhou, Liang, Alaswad, Ahmed, Joosten, Leo A.B., van Crevel, Reinout, Xu, Cheng-Jian, Netea, Mihai G., Li, Yang

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Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining von Tang, Xiaoyu, Li, Jie, Millán-Aguiñaga, Natalie, Zhang, Jia Jia, O’Neill, Ellis C, Ugalde, Juan A, Jensen, Paul R, Mantovani, Simone M, Moore, Bradley S

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The corona of a surface bubble promotes electrochemical reactions von Vogel, Yan B., Evans, Cameron W., Belotti, Mattia, Xu, Longkun, Russell, Isabella C., Yu, Li-Juan, Fung, Alfred K. K., Hill, Nicholas S., Darwish, Nadim, Gonçales, Vinicius R., Coote, Michelle L., Swaminathan Iyer, K., Ciampi, Simone

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selenoproteome exhibits widely varying, tissue-specific dependence on selenoprotein P for selenium supply von Hoffmann, Peter R, Höge, Simone C, Li, Ping-An, Hoffmann, Fukun W, Hashimoto, Ann C, Berry, Marla J

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The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity von Domínguez-Andrés, Jorge, Novakovic, Boris, Li, Yang, Scicluna, Brendon P., Gresnigt, Mark S., Arts, Rob J.W., Oosting, Marije, Moorlag, Simone J.C.F.M., Groh, Laszlo A., Zwaag, Jelle, Koch, Rebecca M., ter Horst, Rob, Joosten, Leo A.B., Wijmenga, Cisca, Michelucci, Alessandro, van der Poll, Tom, Kox, Matthijs, Pickkers, Peter, Kumar, Vinod, Stunnenberg, Henk, Netea, Mihai G.

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Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity von Moorlag, Simone J C F M, Folkman, Lukas, Ter Horst, Rob, Krausgruber, Thomas, Barreca, Daniele, Schuster, Linda C, Fife, Victoria, Matzaraki, Vasiliki, Li, Wenchao, Reichl, Stephan, Mourits, Vera P, Koeken, Valerie A C M, de Bree, L Charlotte J, Dijkstra, Helga, Lemmers, Heidi, van Cranenbroek, Bram, van Rijssen, Esther, Koenen, Hans J P M, Joosten, Irma, Xu, Cheng-Jian, Li, Yang, Joosten, Leo A B, van Crevel, Reinout, Netea, Mihai G, Bock, Christoph

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Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs von Li, Na, Rowley, Simone M, Thompson, Ella R, McInerny, Simone, Devereux, Lisa, Amarasinghe, Kaushalya C, Zethoven, Magnus, Lupat, Richard, Goode, David, Li, Jason, Trainer, Alison H, Gorringe, Kylie L, James, Paul A, Campbell, Ian G

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