Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma von Carter, Julia H, Deddens, James A, Spaulding IV, Nelson Reed, Lucas, Denise, Colligan, Bruce M, Lewis, Thomas Grant, Hawkins, Elyse, Jones, Jordan, Pemberton, Jackson O, Douglass, Larry E, Graff, Jeremy R

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Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase von El Sahly, Hana M, Baden, Lindsey R, Essink, Brandon, Doblecki-Lewis, Susanne, Martin, Judith M, Anderson, Evan J, Campbell, Thomas B, Clark, Jesse, Jackson, Lisa A, Fichtenbaum, Carl J, Zervos, Marcus, Rankin, Bruce, Eder, Frank, Feldman, Gregory, Kennelly, Christina, Han-Conrad, Laurie, Levin, Michael, Neuzil, Kathleen M, Corey, Lawrence, Gilbert, Peter, Janes, Holly, Follmann, Dean, Marovich, Mary, Polakowski, Laura, Mascola, John R, Ledgerwood, Julie E, Graham, Barney S, August, Allison, Clouting, Heather, Deng, Weiping, Han, Shu, Leav, Brett, Manzo, Deb, Pajon, Rolando, Schödel, Florian, Tomassini, Joanne E, Zhou, Honghong, Miller, Jacqueline

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Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal von Mitchell, Thomas J., Turajlic, Samra, Rowan, Andrew, Nicol, David, Farmery, James H.R., O’Brien, Tim, Martincorena, Inigo, Tarpey, Patrick, Angelopoulos, Nicos, Yates, Lucy R., Butler, Adam P., Raine, Keiran, Stewart, Grant D., Challacombe, Ben, Fernando, Archana, Lopez, Jose I., Hazell, Steve, Chandra, Ashish, Chowdhury, Simon, Rudman, Sarah, Soultati, Aspasia, Stamp, Gordon, Fotiadis, Nicos, Pickering, Lisa, Au, Lewis, Spain, Lavinia, Lynch, Joanna, Stares, Mark, Teague, Jon, Maura, Francesco, Wedge, David C., Horswell, Stuart, Chambers, Tim, Litchfield, Kevin, Xu, Hang, Stewart, Aengus, Elaidi, Reza, Oudard, Stéphane, McGranahan, Nicholas, Csabai, Istvan, Gore, Martin, Futreal, P. Andrew, Larkin, James, Lynch, Andy G., Szallasi, Zoltan, Swanton, Charles, Campbell, Peter J.

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Sea spray aerosol as a unique source of ice nucleating particles von DeMott, Paul J., Hill, Thomas C. J., McCluskey, Christina S., Prather, Kimberly A., Collins, Douglas B., Sullivan, Ryan C., Ruppel, Matthew J., Mason, Ryan H., Irish, Victoria E., Lee, Taehyoung, Hwang, Chung Yeon, Rhee, Tae Siek, Snider, Jefferson R., McMeeking, Gavin R., Dhaniyala, Suresh, Lewis, Ernie R., Wentzell, Jeremy J. B., Abbatt, Jonathan, Lee, Christopher, Sultana, Camille M., Ault, Andrew P., Axson, Jessica L., Martinez, Myrelis Diaz, Venero, Ingrid, Santos-Figueroa, Gilmarie, Stokes, M. Dale, Deane, Grant B., Mayol-Bracero, Olga L., Grassian, Vicki H., Bertram, Timothy H., Bertram, Allan K., Moffett, Bruce F., Franc, Gary D.

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Impact of Perioperative Allogeneic and Autologous Blood Transfusion on Acute Wound Infection Following Total Knee and Total Hip Arthroplasty von Newman, Erik T, Watters, Tyler Steven, Lewis, John S, Jennings, Jason M, Wellman, Samuel S, Attarian, David E, Grant, Stuart A, Green, Cynthia L, Vail, Thomas P, Bolognesi, Michael P

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Cerebral small vessel disease genomics and its implications across the lifespan von Sargurupremraj, Muralidharan, Suzuki, Hideaki, Jian, Xueqiu, Sarnowski, Chloé, Evans, Tavia E., Eiriksdottir, Gudny, Sakaue, Saori, Terzikhan, Natalie, Zhao, Wei, Armstrong, Nicola J., Yanek, Lisa R., Kumar, Rajan B., van den Akker, Erik B., McWhirter, Rebekah E., Trompet, Stella, Mishra, Aniket, Saba, Yasaman, Satizabal, Claudia L., Beaudet, Gregory, Petit, Laurent, Tsuchida, Ami, Schilling, Sabrina, Sigurdsson, Sigurdur, Lewis, Cora E., Lopez, Oscar L., Smith, Jennifer A., Valdés Hernández, Maria C., van der Grond, Jeroen, Wright, Margaret J., Knol, Maria J., Thomson, Russell J., Le Grand, Quentin, Duperron, Marie-Gabrielle, Smith, Albert V., Schreiner, Pamela J., Evans, Denis A., Rotter, Jerome I., Beiser, Alexa S., Maniega, Susana Muñoz, Beekman, Marian, Trollor, Julian, Stott, David J., Vernooij, Meike W., Wittfeld, Katharina, Niessen, Wiro J., Soumaré, Aicha, Sidney, Stephen, Turner, Stephen T., Davies, Gail, Thalamuthu, Anbupalam, Völker, Uwe, van Buchem, Mark A., Dupuis, Josée, Bastin, Mark E., Teumer, Alexander, Amouyel, Philippe, Kwok, John B., Bülow, Robin, Deary, Ian J., Schofield, Peter R., Brodaty, Henry, Jiang, Jiyang, Tabara, Yasuharu, Setoh, Kazuya, Miyamoto, Susumu, Yoshida, Kazumichi, Nagata, Manabu, Matsuda, Fumihiko, Psaty, Bruce M., Bennett, David A., De Jager, Philip L., Mosley, Thomas H., Sachdev, Perminder S., Schmidt, Reinhold, Evangelou, Evangelos, Trégouët, David-Alexandre, Ikram, Mohammad A., DeCarli, Charles, Srikanth, Velandai K., Jukema, J. Wouter, Slagboom, Eline P., Kardia, Sharon L. R., Okada, Yukinori, Mazoyer, Bernard, Wardlaw, Joanna M., Nyquist, Paul A., Mather, Karen A., Grabe, Hans J., Schmidt, Helena, Van Duijn, Cornelia M., Gudnason, Vilmundur, Longstreth, William T., Launer, Lenore J., Lathrop, Mark, Seshadri, Sudha, Tzourio, Christophe, Adams, Hieab H., Matthews, Paul M., Fornage, Myriam, Debette, Stéphanie

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Identification of a chemical probe for NAADP by virtual screening von Naylor, Edmund, Rosen, Daniel, Vasudevan, Sridhar R, Thomas, Justyn M, Ganesan, A, Churchill, Grant C, Galione, Antony, Parkesh, Raman, Arredouani, Abdelilah, Lewis, Alexander M, Izumi, Minoru, Mizote, Akiko

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Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib von Sosman, Jeffrey A, Kim, Kevin B, Schuchter, Lynn, Gonzalez, Rene, Pavlick, Anna C, Weber, Jeffrey S, McArthur, Grant A, Hutson, Thomas E, Moschos, Stergios J, Flaherty, Keith T, Hersey, Peter, Kefford, Richard, Lawrence, H. Jeffrey, Lawrence, Donald, Puzanov, Igor, Lewis, Karl D, Amaravadi, Ravi K, Chmielowski, Bartosz, Shyr, Yu, Ye, Fei, Li, Jiang, Nolop, Keith B, Lee, Richard J, Joe, Andrew K, Ribas, Antoni

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Identification of common genetic risk variants for autism spectrum disorder von Grove, Jakob, Ripke, Stephan, Als, Thomas D., Mattheisen, Manuel, Walters, Raymond K., Won, Hyejung, Pallesen, Jonatan, Agerbo, Esben, Andreassen, Ole A., Anney, Richard, Awashti, Swapnil, Belliveau, Rich, Bettella, Francesco, Buxbaum, Joseph D., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Cerrato, Felecia, Chambert, Kimberly, Christensen, Jane H., Churchhouse, Claire, Dellenvall, Karin, Demontis, Ditte, De Rubeis, Silvia, Devlin, Bernie, Djurovic, Srdjan, Dumont, Ashley L., Goldstein, Jacqueline I., Hansen, Christine S., Hauberg, Mads Engel, Hollegaard, Mads V., Hope, Sigrun, Howrigan, Daniel P., Huang, Hailiang, Hultman, Christina M., Klei, Lambertus, Maller, Julian, Martin, Joanna, Martin, Alicia R., Moran, Jennifer L., Nyegaard, Mette, Nærland, Terje, Palmer, Duncan S., Palotie, Aarno, Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, dPoterba, Timothy, Poulsen, Jesper Buchhave, Pourcain, Beate St, Qvist, Per, Rehnström, Karola, Reichenberg, Abraham, Reichert, Jennifer, Robinson, Elise B., Roeder, Kathryn, Roussos, Panos, Saemundsen, Evald, Sandin, Sven, Satterstrom, F. Kyle, Davey Smith, George, Stefansson, Hreinn, Steinberg, Stacy, Stevens, Christine R., Sullivan, Patrick F., Turley, Patrick, Walters, G. Bragi, Xu, Xinyi, Stefansson, Kari, Geschwind, Daniel H., Nordentoft, Merete, Hougaard, David M., Werge, Thomas, Mors, Ole, Mortensen, Preben Bo, Neale, Benjamin M., Daly, Mark J., Børglum, Anders D.

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Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study von Ribas, Antoni, Gonzalez, Rene, Pavlick, Anna, Hamid, Omid, Gajewski, Thomas F, Daud, Adil, Flaherty, Lawrence, Logan, Theodore, Chmielowski, Bartosz, Lewis, Karl, Kee, Damien, Boasberg, Peter, Yin, Ming, Chan, Iris, Musib, Luna, Choong, Nicholas, Puzanov, Igor, McArthur, Grant A

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Catheter ablation of atrial fibrillation in patients with heart failure and preserved ejection fraction von Black-Maier, Eric, Ren, Xinru, Steinberg, Benjamin A., Green, Cynthia L., Barnett, Adam S., Rosa, Normita Sta, Al-Khatib, Sana M., Atwater, Brett D., Daubert, James P., Frazier-Mills, Camille, Grant, Augustus O., Hegland, Donald D., Jackson, Kevin P., Jackson, Larry R., Koontz, Jason I., Lewis, Robert K., Sun, Albert Y., Thomas, Kevin L., Bahnson, Tristam D., Piccini, Jonathan P.

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Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAF(V600) mutation-positive melanoma (IMspire150): primary analysis of the randomised,... von Gutzmer, Ralf, Stroyakovskiy, Daniil, Gogas, Helen, Robert, Caroline, Lewis, Karl, Protsenko, Svetlana, Pereira, Rodrigo P., Eigentler, Thomas, Rutkowski, Piotr, Demidov, Lev, Manikhas, Georgy Moiseevich, Yan, Yibing, Huang, Kuan-Chieh, Uyei, Anne, McNally, Virginia, McArthur, Grant A., Ascierto, Paolo A.

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Pharmacodynamic Effects and Mechanisms of Resistance to Vemurafenib in Patients With Metastatic Melanoma von TRUNZER, Kerstin, PAVLICK, Anna C, HERSEY, Peter, LONG, Georgina V, LAWRENCE, Donald, OTT, Patrick A, AMARAVADI, Ravi K, LEWIS, Karl D, PUZANOV, Igor, LO, Roger S, KOEHLER, Astrid, KOCKX, Mark, SCHUCHTER, Lynn, SPLEISS, Olivia, SCHELL-STEVEN, Annette, GILBERT, Houston N, COCKEY, Louise, BOLLAG, Gideon, LEE, Richard J, JOE, Andrew K, SOSMAN, Jeffrey A, RIBAS, Antoni, GONZALEZ, Rene, MCARTHUR, Grant A, HUTSON, Thomas E, MOSCHOS, Stergios J, FLAHERTY, Keith T, KIM, Kevin B, WEBER, Jeffrey S

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Biallelic mutations in SORD cause a common and potentially treatable hereditary neuropathy with implications for diabetes von Cortese, Andrea, Zhu, Yi, Rebelo, Adriana P., Negri, Sara, Courel, Steve, Abreu, Lisa, Bacon, Chelsea J., Bai, Yunhong, Bis-Brewer, Dana M., Bugiardini, Enrico, Buglo, Elena, Danzi, Matt C., Feely, Shawna M. E., Athanasiou-Fragkouli, Alkyoni, Haridy, Nourelhoda A., Isasi, Rosario, Khan, Alaa, Laurà, Matilde, Magri, Stefania, Pipis, Menelaos, Pisciotta, Chiara, Powell, Eric, Rossor, Alexander M., Saveri, Paola, Sowden, Janet E., Tozza, Stefano, Vandrovcova, Jana, Dallman, Julia, Grignani, Elena, Marchioni, Enrico, Scherer, Steven S., Tang, Beisha, Lin, Zhiqiang, Al-Ajmi, Abdullah, Schüle, Rebecca, Synofzik, Matthis, Maisonobe, Thierry, Stojkovic, Tanya, Auer-Grumbach, Michaela, Abdelhamed, Mohamed A., Hamed, Sherifa A., Zhang, Ruxu, Manganelli, Fiore, Santoro, Lucio, Taroni, Franco, Pareyson, Davide, Houlden, Henry, Herrmann, David N., Reilly, Mary M., Shy, Michael E., Zhai, R. Grace, Zuchner, Stephan

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A molecular dynamics simulation study of crystalline 1,3,5-triamino-2,4,6-trinitrobenzene as a function of pressure and temperature von Bedrov, Dmitry, Borodin, Oleg, Smith, Grant D, Sewell, Thomas D, Dattelbaum, Dana M, Stevens, Lewis L

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Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome c oxidase von Ishigami, Izumi, Lewis-Ballester, Ariel, Echelmeier, Austin, Brehm, Gerrit, Zatsepin, Nadia A., Grant, Thomas D., Coe, Jesse D., Lisova, Stella, Nelson, Garrett, Zhang, Shangji, Dobson, Zachary F., Boutet, Sébastien, Sierra, Raymond G., Batyuk, Alexander, Fromme, Petra, Fromme, Raimund, Spence, John C. H., Ros, Alexandra, Yeh, Syun-Ru, Rousseau, Denis L.

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Role of NAADP and cADPR in the Induction and Maintenance of Agonist-Evoked Ca2+ Spiking in Mouse Pancreatic Acinar Cells von Yamasaki, Michiko, Thomas, Justyn M., Churchill, Grant C., Garnham, Clive, Lewis, Alexander M., Cancela, Jose-Manuel, Patel, Sandip, Galione, Antony

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Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in BRAF-Mutant Melanoma von Ribas, Antoni, Daud, Adil, Pavlick, Anna C., Gonzalez, Rene, Lewis, Karl D., Hamid, Omid, Gajewski, Thomas F., Puzanov, Igor, Wongchenko, Matthew, Rooney, Isabelle, Hsu, Jessie J., Yan, Yibing, Park, Erica, McArthur, Grant A.

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The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction von Berger, Miles, Oyeyemi, Deborah, Olurinde, Mobolaji O., Whitson, Heather E., Weinhold, Kent J., Woldorff, Marty G., Lipsitz, Lewis A., Moretti, Eugene, Giattino, Charles M., Roberts, Kenneth C., Zhou, Junhong, Bunning, Thomas, Ferrandino, Michael, Scheri, Randall P., Cooter, Mary, Chan, Cliburn, Cabeza, Roberto, Browndyke, Jeffrey N., Murdoch, David M., Devinney, Michael J., Shaw, Leslie M., Cohen, Harvey Jay, Mathew, Joseph P., Akinyemi, Oladayo, Amundsen, Cindy, Avasarala, Pallavi, Barber, Matthew, Beach, Rachel, Berchuck, Andrew, Blazer, Dan G., Bolognesi, Michael, Brassard, Rachele, Bullock, W. Michael, Burke, Ashley, Cai, Victor, Cheong, Vanessa, Christensen, Soren, Cox, Mitchell, Crabtree, Donna, D'Amico, Thomas, Davidson, Brittany, Deorio, James, Easley, Mark E., Ehieli, Eric, Erdmann, Detlev, Funk, Bonita, Gadsden, Jeffrey, Garrigues, Grant, Greenup, Rachel, Habib, Ashraf, Harpole, David, Hartwig, Matthew, Havrilesky, Laura, Henley, Tarrah, Holland, Courtney, Hollenbeck, Scott, Huang, Richard, Iboaya, Ehimenem, Kawasaki, Amie, Klapper, Jacob, Knechtle, Stuart J., Lagoo‐Deenadayalan, Sandhya, Lee, Walter T., Lewis, Brian D., Lipkin, Michael, Litchfield, Heather, Marlor, Ellie, Maxwell, Cory, Migaly, John, Moul, Judd, Olson, Steven, Pappas, Theodore, Pellom, Gary Lee, Peterson, Andrew, Podgoreanu, Andreea, Polascik, Thomas, Preminger, Glenn, Previs, Rebecca, Rampersaud, Edward, Renne, Angela, Roman, Sanziana, Sanders, Edward, Sandler, Aaron, Scales, Charles, Seymour, Keri, Shah, Kevin N., Stang, Michael, Stanley, Samuel, Sweeney, Katherine, Szydlowska, Alicja, Terrando, Niccolo, Thacker, Julie, Thomas, Jake, Tong, Betty, Toulgoat‐DuBois, Yanne, Wellman, Samuel, Williams, David, Zani, Sabino, Enzor, Jennifer H., Staats, Janet

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Natural history of Charcot-Marie-Tooth disease type 2A: a large international multicentre study von Pipis, Menelaos, Feely, Shawna M. E., Polke, James M., Skorupinska, Mariola, Perez, Laura, Shy, Rosemary R., Laura, Matilde, Morrow, Jasper M., Moroni, Isabella, Pisciotta, Chiara, Taroni, Franco, Vujovic, Dragan, Lloyd, Thomas E., Acsadi, Gyula, Yum, Sabrina W., Lewis, Richard A., Finkel, Richard S., Herrmann, David N., Day, John W., Li, Jun, Saporta, Mario, Sadjadi, Reza, Walk, David, Burns, Joshua, Muntoni, Francesco, Ramchandren, Sindhu, Horvath, Rita, Johnson, Nicholas E., Zuchner, Stephan, Pareyson, Davide, Scherer, Steven S., Rossor, Alexander M., Shy, Michael E., Reilly, Mary M.

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