Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence von Lewis, Natasha S, Lewis, Emily EL, Mullin, Margaret, Wheadon, Helen, Dalby, Matthew J, Berry, Catherine C

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Mass Spectrometry Imaging of 3D Tissue Models von Russo, Cristina, Lewis, Emily E. L., Flint, Lucy, Clench, Malcolm R.

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The influence of particle size and static magnetic fields on the uptake of magnetic nanoparticles into three dimensional cell-seeded collagen gel cultures von Lewis, Emily E. L., Child, Hannah W., Hursthouse, Andrew, Stirling, David, McCully, Mark, Paterson, David, Mullin, Margaret, Berry, Catherine C.

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Front Cover: Mass Spectrometry Imaging of 3D Tissue Models von Russo, Cristina, Lewis, Emily E. L., Flint, Lucy, Clench, Malcolm R.

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Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association von Tsao, Connie W., Aday, Aaron W., Almarzooq, Zaid I., Alonso, Alvaro, Beaton, Andrea Z., Bittencourt, Marcio S., Boehme, Amelia K., Buxton, Alfred E., Carson, April P., Commodore-Mensah, Yvonne, Elkind, Mitchell S.V., Evenson, Kelly R., Eze-Nliam, Chete, Ferguson, Jane F., Generoso, Giuliano, Ho, Jennifer E., Kalani, Rizwan, Khan, Sadiya S., Kissela, Brett M., Knutson, Kristen L., Levine, Deborah A., Lewis, Tené T., Liu, Junxiu, Loop, Matthew Shane, Ma, Jun, Mussolino, Michael E., Navaneethan, Sankar D., Perak, Amanda Marma, Poudel, Remy, Rezk-Hanna, Mary, Roth, Gregory A., Schroeder, Emily B., Shah, Svati H., Thacker, Evan L., VanWagner, Lisa B., Virani, Salim S., Voecks, Jenifer H., Wang, Nae-Yuh, Yaffe, Kristine, Martin, Seth S.

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Isolated Metal Atom Geometries as a Strategy for Selective Heterogeneous Hydrogenations von Kyriakou, Georgios, Boucher, Matthew B., Jewell, April D., Lewis, Emily A., Lawton, Timothy J., Baber, Ashleigh E., Tierney, Heather L., Flytzani-Stephanopoulos, Maria, Sykes, E. Charles H.

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High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging von He, Shanshan, Bhatt, Ruchir, Brown, Carl, Brown, Emily A., Buhr, Derek L., Chantranuvatana, Kan, Danaher, Patrick, Dunaway, Dwayne, Garrison, Ryan G., Geiss, Gary, Gregory, Mark T., Hoang, Margaret L., Khafizov, Rustem, Killingbeck, Emily E., Kim, Dae, Kim, Tae Kyung, Kim, Youngmi, Klock, Andrew, Korukonda, Mithra, Kutchma, Alecksandr, Lewis, Zachary R., Liang, Yan, Nelson, Jeffrey S., Ong, Giang T., Perillo, Evan P., Phan, Joseph C., Phan-Everson, Tien, Piazza, Erin, Rane, Tushar, Reitz, Zachary, Rhodes, Michael, Rosenbloom, Alyssa, Ross, David, Sato, Hiromi, Wardhani, Aster W., Williams-Wietzikoski, Corey A., Wu, Lidan, Beechem, Joseph M.

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Population‐Based Incidence and Prevalence of Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program von Somers, Emily C., Marder, Wendy, Cagnoli, Patricia, Lewis, Emily E., DeGuire, Peter, Gordon, Caroline, Helmick, Charles G., Wang, Lu, Wing, Jeffrey J., Dhar, J. Patricia, Leisen, James, Shaltis, Diane, McCune, W. Joseph

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Exercise Pulmonary Hypertension Predicts Clinical Outcomes in Patients With Dyspnea on Effort von Ho, Jennifer E., Zern, Emily K., Lau, Emily S., Wooster, Luke, Bailey, Cole S., Cunningham, Thomas, Eisman, Aaron S., Hardin, Kathryn M., Farrell, Robyn, Sbarbaro, John A., Schoenike, Mark W., Houstis, Nicholas E., Baggish, Aaron L., Shah, Ravi V., Nayor, Matthew, Malhotra, Rajeev, Lewis, Gregory D.

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Myalgic Encephalomyelitis—Chronic Fatigue Syndrome Common Data Element item content analysis von Slavin, Mary D, Bailey, Hannah M, Hickey, Emily J, Vasudevan, Ananya, Ledingham, Aileen, Tannenbaum, Linda, Bateman, Lucinda, Kaufman, David L, Peterson, Daniel L, Ruhoy, Ilene S, Systrom, David M, Felsenstein, Donna, Kazis, Lewis E

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Cell-programmed nutrient partitioning in the tumour microenvironment von Reinfeld, Bradley I., Madden, Matthew Z., Wolf, Melissa M., Chytil, Anna, Bader, Jackie E., Patterson, Andrew R., Sugiura, Ayaka, Cohen, Allison S., Ali, Ahmed, Do, Brian T., Muir, Alexander, Lewis, Caroline A., Hongo, Rachel A., Young, Kirsten L., Brown, Rachel E., Todd, Vera M., Huffstater, Tessa, Abraham, Abin, O’Neil, Richard T., Wilson, Matthew H., Xin, Fuxue, Tantawy, M. Noor, Merryman, W. David, Johnson, Rachelle W., Williams, Christopher S., Mason, Emily F., Mason, Frank M., Beckermann, Katherine E., Vander Heiden, Matthew G., Manning, H. Charles, Rathmell, Jeffrey C., Rathmell, W. Kimryn

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Hospitalizations and Deaths Associated with EVALI von Werner, Angela K, Koumans, Emilia H, Chatham-Stephens, Kevin, Salvatore, Phillip P, Armatas, Christina, Byers, Paul, Clark, Charles R, Ghinai, Isaac, Holzbauer, Stacy M, Navarette, Kristen A, Danielson, Melissa L, Ellington, Sascha, Moritz, Erin D, Petersen, Emily E, Kiernan, Emily A, Baldwin, Grant T, Briss, Peter, Jones, Christopher M, King, Brian A, Krishnasamy, Vikram, Rose, Dale A, Reagan-Steiner, Sarah

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Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association von Virani, Salim S., Alonso, Alvaro, Benjamin, Emelia J., Bittencourt, Marcio S., Callaway, Clifton W., Carson, April P., Chamberlain, Alanna M., Chang, Alexander R., Cheng, Susan, Delling, Francesca N., Djousse, Luc, Elkind, Mitchell S.V., Ferguson, Jane F., Fornage, Myriam, Khan, Sadiya S., Kissela, Brett M., Knutson, Kristen L., Kwan, Tak W., Lackland, Daniel T., Lewis, Tené T., Lichtman, Judith H., Longenecker, Chris T., Loop, Matthew Shane, Lutsey, Pamela L., Martin, Seth S., Matsushita, Kunihiro, Moran, Andrew E., Mussolino, Michael E., Perak, Amanda Marma, Rosamond, Wayne D., Roth, Gregory A., Sampson, Uchechukwu K.A., Satou, Gary M., Schroeder, Emily B., Shah, Svati H., Shay, Christina M., Spartano, Nicole L., Stokes, Andrew, Tirschwell, David L., VanWagner, Lisa B., Tsao, Connie W.

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Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association von Virani, Salim S., Alonso, Alvaro, Aparicio, Hugo J., Benjamin, Emelia J., Bittencourt, Marcio S., Callaway, Clifton W., Carson, April P., Chamberlain, Alanna M., Cheng, Susan, Delling, Francesca N., Elkind, Mitchell S.V., Evenson, Kelly R., Ferguson, Jane F., Gupta, Deepak K., Khan, Sadiya S., Kissela, Brett M., Knutson, Kristen L., Lee, Chong D., Lewis, Tené T., Liu, Junxiu, Loop, Matthew Shane, Lutsey, Pamela L., Ma, Jun, Mackey, Jason, Martin, Seth S., Matchar, David B., Mussolino, Michael E., Navaneethan, Sankar D., Perak, Amanda Marma, Roth, Gregory A., Samad, Zainab, Satou, Gary M., Schroeder, Emily B., Shah, Svati H., Shay, Christina M., Stokes, Andrew, VanWagner, Lisa B., Wang, Nae-Yuh, Tsao, Connie W.

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Deconvolution of cancer cell states by the XDec-SM method von Murillo, Oscar D, Petrosyan, Varduhi, LaPlante, Emily L, Dobrolecki, Lacey E, Lewis, Michael T, Milosavljevic, Aleksandar

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Targeted long-read sequencing identifies missing disease-causing variation von Miller, Danny E., Sulovari, Arvis, Wang, Tianyun, Loucks, Hailey, Hoekzema, Kendra, Munson, Katherine M., Lewis, Alexandra P., Fuerte, Edith P. Almanza, Paschal, Catherine R., Walsh, Tom, Thies, Jenny, Bennett, James T., Glass, Ian, Dipple, Katrina M., Patterson, Karynne, Bonkowski, Emily S., Nelson, Zoe, Squire, Audrey, Sikes, Megan, Beckman, Erika, Bennett, Robin L., Earl, Dawn, Lee, Winston, Allikmets, Rando, Perlman, Seth J., Chow, Penny, Hing, Anne V., Wenger, Tara L., Adam, Margaret P., Sun, Angela, Lam, Christina, Chang, Irene, Zou, Xue, Austin, Stephanie L., Huggins, Erin, Safi, Alexias, Iyengar, Apoorva K., Reddy, Timothy E., Majoros, William H., Allen, Andrew S., Crawford, Gregory E., Kishnani, Priya S., King, Mary-Claire, Cherry, Tim, Chong, Jessica X., Bamshad, Michael J., Nickerson, Deborah A., Mefford, Heather C., Doherty, Dan, Eichler, Evan E.

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Practice Pattern Variability in the Management of Regional Lymph Node Metastasis in Extremity and Trunk Soft Tissue Sarcoma: A Survey of the Society of Surgical Oncology and Muscul... von Witt, Russell G., Voss, Rachel K., Chiang, Yi-Ju, Nguyen, Sa, Scally, Christopher P., Lin, Patrick P., Torres, Keila E., Moon, Bryan S., Satcher, Robert L., Hunt, Kelly K., Bird, Justin E., Feig, Barry W., Lewis, Valerae O., Roland, Christina L., Keung, Emily Z.

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Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus von Bowman, Louise, Mafham, Marion, Wallendszus, Karl, Stevens, Will, Buck, Georgina, Barton, Jill, Murphy, Kevin, Aung, Theingi, Haynes, Richard, Cox, Jolyon, Murawska, Aleksandra, Young, Allen, Lay, Michael, Chen, Fang, Sammons, Emily, Waters, Emma, Adler, Amanda, Bodansky, Jonathan, Farmer, Andrew, McPherson, Roger, Neil, Andrew, Simpson, David, Peto, Richard, Baigent, Colin, Collins, Rory, Parish, Sarah, Armitage, Jane

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An atlas of substrate specificities for the human serine/threonine kinome von Johnson, Jared L., Yaron, Tomer M., Huntsman, Emily M., Kerelsky, Alexander, Song, Junho, Regev, Amit, Lin, Ting-Yu, Liberatore, Katarina, Cizin, Daniel M., Cohen, Benjamin M., Vasan, Neil, Ma, Yilun, Krismer, Konstantin, Robles, Jaylissa Torres, van de Kooij, Bert, van Vlimmeren, Anne E., Andrée-Busch, Nicole, Käufer, Norbert F., Dorovkov, Maxim V., Ryazanov, Alexey G., Takagi, Yuichiro, Kastenhuber, Edward R., Goncalves, Marcus D., Hopkins, Benjamin D., Elemento, Olivier, Taatjes, Dylan J., Maucuer, Alexandre, Yamashita, Akio, Degterev, Alexei, Uduman, Mohamed, Lu, Jingyi, Landry, Sean D., Zhang, Bin, Cossentino, Ian, Linding, Rune, Blenis, John, Hornbeck, Peter V., Turk, Benjamin E., Yaffe, Michael B., Cantley, Lewis C.

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Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus von Bowman, Louise, Mafham, Marion, Wallendszus, Karl, Stevens, Will, Buck, Georgina, Barton, Jill, Murphy, Kevin, Aung, Theingi, Haynes, Richard, Cox, Jolyon, Murawska, Aleksandra, Young, Allen, Lay, Michael, Chen, Fang, Sammons, Emily, Waters, Emma, Adler, Amanda, Bodansky, Jonathan, Farmer, Andrew, McPherson, Roger, Neil, Andrew, Simpson, David, Peto, Richard, Baigent, Colin, Collins, Rory, Parish, Sarah, Armitage, Jane

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