Application of boosting to classification problems in chemometrics von Zhang, M.H., Xu, Q.S., Daeyaert, F., Lewi, P.J., Massart, D.L.

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Improving QSAR models for the biological activity of HIV Reverse Transcriptase inhibitors: Aspects of outlier detection and uninformative variable elimination von Daszykowski, M., Stanimirova, I., Walczak, B., Daeyaert, F., de Jonge, M.R., Heeres, J., Koymans, L.M.H., Lewi, P.J., Vinkers, H.M., Janssen, P.A., Massart, D.L.

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Classification and Regression TreesStudies of HIV Reverse Transcriptase Inhibitors von Daszykowski, M, Walczak, B, Xu, Q.-S, Daeyaert, F, de Jonge, M. R, Heeres, J, Koymans, L. M. H, Lewi, P. J, Vinkers, H. M, Janssen, P. A, Massart, D. L

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Synthesis of Novel Diarylpyrimidine Analogues and Their Antiviral Activity against Human Immunodeficiency Virus Type 1 von Guillemont, Jerome, Pasquier, Elisabeth, Palandjian, Patrice, Vernier, Daniel, Gaurrand, Sandrine, Lewi, Paul J, Heeres, Jan, de Jonge, Marc R, Koymans, Lucien M. H, Daeyaert, Frits F. D, Vinkers, Maarten H, Arnold, Eddy, Das, Kalyan, Pauwels, Rudi, Andries, Koen, de Béthune, Marie-Pierre, Bettens, Eva, Hertogs, Kurt, Wigerinck, Piet, Timmerman, Philip, Janssen, Paul A. J

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Evolution of anti-HIV drug candidates. Part 3: diarylpyrimidine (DAPY) analogues von Ludovici, Donald W., De Corte, Bart L., Kukla, Michael J., Ye, Hong, Ho, Chih Y., Lichtenstein, Mark A., Kavash, Robert W., Andries, Koen, de Béthune, Marie-Pierre, Azijn, Hilde, Pauwels, Rudi, Lewi, Paul J., Heeres, Jan, Koymans, Lucien M.H., de Jonge, Marc R., Van Aken, Koen J.A., Daeyaert, Frederik F.D., Das, Kalyan, Arnold, Edward, Janssen, Paul A.J.

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Two groups of rhinoviruses revealed by a panel of antiviral compounds present sequence divergence and differential pathogenicity von ANDRIES, K, DEWINDT, B, SNOEKS, J, WOUTERS, L, MOEREELS, H, LEWI, P. J, JANSSEN, P. A

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Evolution of anti-HIV drug candidates. Part 2 : Diaryltriazine (DATA) analogues von LUDOVICI, Donald W, KAVASH, Robert W, MOEREELS, Henry E. L, HEERES, Jan, KOYMANS, Lucien M. H, DE JONGE, Marc R, VAN AKEN, Koen J. A, DAEYAERT, Frederik F. D, LEWI, Paul J, DAS, Kalyan, ARNOLD, Edward, JANSSEN, Paul A. J, KUKLA, Michael J, HO, Chih Y, HONG YE, DE CORTE, Bart L, ANDRIES, Koen, DE BETHUNE, Marie-Pierre, AZIJN, Hilde, PAUWELS, Rudi

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Inhibition and substrate recognition--a computational approach applied to HIV protease von Vinkers, H M, de Jonge, M R, Daeyaert, E D, Heeres, J, Koymans, L M H, van Lenthe, J H, Lewi, P J, Timmerman, H, Janssen, P A J

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In Search of a Novel Anti-HIV Drug:  Multidisciplinary Coordination in the Discovery of 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile... von Janssen, Paul A. J, Lewi, Paul J, Arnold, Eddy, Daeyaert, Frits, de Jonge, Marc, Heeres, Jan, Koymans, Luc, Vinkers, Maarten, Guillemont, Jérôme, Pasquier, Elisabeth, Kukla, Mike, Ludovici, Don, Andries, Koen, de Béthune, Marie-Pierre, Pauwels, Rudi, Das, Kalyan, Clark, Art D, Frenkel, Yulia Volovik, Hughes, Stephen H, Medaer, Bart, De Knaep, Fons, Bohets, Hilde, De Clerck, Fred, Lampo, Ann, Williams, Peter, Stoffels, Paul

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Studies of relationship between biological activities and HIV Reverse Transcriptase Inhibitors by Multivariate Adaptive Regression Splines with Curds and Whey von Xu, Q.S., Daeyaert, F., Lewi, P.J., Massart, D.L.

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Multivariate adaptive regression splines—studies of HIV reverse transcriptase inhibitors von Xu, Q.-S., Daszykowski, M., Walczak, B., Daeyaert, F., de Jonge, M.R., Heeres, J., Koymans, L.M.H., Lewi, P.J., Vinkers, H.M., Janssen, P.A., Massart, D.L.

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Using genetic algorithms for the construction of phylogenetic trees: application to G-protein coupled receptor sequences von Reijmers, T.H, Wehrens, R, Daeyaert, F.D, Lewi, P.J, Buydens, L.M.C

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Classification and identification of proteins by means of common and specific amino acid n-tuples in unaligned sequences von Daeyaert, Frits, Moereels, Henri, Lewi, Paul J

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Structure Based Activity Prediction of HIV-1 Reverse Transcriptase Inhibitors von de Jonge, Marc R, Koymans, Lucien M. H, Vinkers, H. Maarten, Daeyaert, Frits F. D, Heeres, Jan, Lewi, Paul J, Janssen, Paul A. J

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Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase... von Das, Kalyan, Lewi, Paul J., Hughes, Stephen H., Arnold, Eddy

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A comparative test of fifteen compounds against all known human rhinovirus serotypes as a basis for a more rational screening program von Andries, K., Dewindt, B., Snoeks, J., Willebrords, R., Stokbroekx, R., Lewi, P.J.

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Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Hi... von Das, Kalyan, Clark, Arthur D, Lewi, Paul J, Heeres, Jan, de Jonge, Marc R, Koymans, Lucien M. H, Vinkers, H. Maarten, Daeyaert, Frederik, Ludovici, Donald W, Kukla, Michael J, De Corte, Bart, Kavash, Robert W, Ho, Chih Y, Ye, Hong, Lichtenstein, Mark. A, Andries, Koen, Pauwels, Rudi, de Béthune, Marie-Pierre, Boyer, Paul L, Clark, Patrick, Hughes, Stephen H, Janssen, Paul A. J, Arnold, Eddy

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Concentration and pH Dependent Aggregation of Hydrophobic Drug Molecules and Relevance to Oral Bioavailability von Frenkel, Yulia Volovik, Clark, Arthur D, Das, Kalyan, Wang, Yuh-Hwa, Lewi, Paul J, Janssen, Paul A. J, Arnold, Eddy

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Combination of dendrograms with plots of latent variables. Application to G-protein coupled receptor sequences von LEWI, P. J, MOEREELS, H, ADRAENSEN, D

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SYNOPSIS:  SYNthesize and OPtimize System in Silico von Vinkers, H. Maarten, de Jonge, Marc R, Daeyaert, Frederik F. D, Heeres, Jan, Koymans, Lucien M. H, van Lenthe, Joop H, Lewi, Paul J, Timmerman, Henk, Van Aken, Koen, Janssen, Paul A. J

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