Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy von Hofmann, Lars, Forschner, Andrea, Loquai, Carmen, Goldinger, Simone M, Zimmer, Lisa, Ugurel, Selma, Schmidgen, Maria I, Gutzmer, Ralf, Utikal, Jochen S, Göppner, Daniela, Hassel, Jessica C, Meier, Friedegund, Tietze, Julia K, Thomas, Ioannis, Weishaupt, Carsten, Leverkus, Martin, Wahl, Renate, Dietrich, Ursula, Garbe, Claus, Kirchberger, Michael C, Eigentler, Thomas, Berking, Carola, Gesierich, Anja, Krackhardt, Angela M, Schadendorf, Dirk, Schuler, Gerold, Dummer, Reinhard, Heinzerling, Lucie M

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cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms von Feoktistova, Maria, Geserick, Peter, Kellert, Beate, Dimitrova, Diana Panayotova, Langlais, Claudia, Hupe, Mike, Cain, Kelvin, MacFarlane, Marion, Häcker, Georg, Leverkus, Martin

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Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate von Hughes, Michelle A., Powley, Ian R., Jukes-Jones, Rebekah, Horn, Sebastian, Feoktistova, Maria, Fairall, Louise, Schwabe, John W.R., Leverkus, Martin, Cain, Kelvin, MacFarlane, Marion

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LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L von Taraborrelli, Lucia, Peltzer, Nieves, Montinaro, Antonella, Kupka, Sebastian, Rieser, Eva, Hartwig, Torsten, Sarr, Aida, Darding, Maurice, Draber, Peter, Haas, Tobias L., Akarca, Ayse, Marafioti, Teresa, Pasparakis, Manolis, Bertin, John, Gough, Peter J., Bouillet, Philippe, Strasser, Andreas, Leverkus, Martin, Silke, John, Walczak, Henning

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Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival von Horn, Sebastian, Hughes, Michelle A., Schilling, Ramon, Sticht, Carsten, Tenev, Tencho, Ploesser, Michaela, Meier, Pascal, Sprick, Martin R., MacFarlane, Marion, Leverkus, Martin

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Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells von Cullen, Sean P., Henry, Conor M., Kearney, Conor J., Logue, Susan E., Feoktistova, Maria, Tynan, Graham A., Lavelle, Ed C., Leverkus, Martin, Martin, Seamus J.

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TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma von Podder, Biswajit, Guttà, Cristiano, Rožanc, Jan, Gerlach, Elke, Feoktistova, Maria, Panayotova-Dimitrova, Diana, Alexopoulos, Leonidas G., Leverkus, Martin, Rehm, Markus

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Programmed necrosis and necroptosis signalling von Feoktistova, Maria, Leverkus, Martin

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Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment von Geserick, Peter, Hupe, Mike, Moulin, Maryline, Wong, W. Wei-Lynn, Feoktistova, Maria, Kellert, Beate, Gollnick, Harald, Silke, John, Leverkus, Martin

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RIPping the Skin Apart: Necroptosis Signaling in Toxic Epidermal Necrolysis von Panayotova-Dimitrova, Diana, Feoktistova, Maria, Leverkus, Martin

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Pick your poison: The Ripoptosome, a cell death platform regulating apoptosis and necroptosis von Feoktistova, Maria, Geserick, Peter, Panayotova-Dimitrova, Diana, Leverkus, Martin

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TNF Is Partially Required for Cell-Death-Triggered Skin Inflammation upon Acute Loss of cFLIP von Feoktistova, Maria, Makarov, Roman, Leverkus, Martin, Yazdi, Amir S., Panayotova-Dimitrova, Diana

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Basal Cell Carcinoma: From the Molecular Understanding of the Pathogenesis to Targeted Therapy of Progressive Disease von Göppner, Daniela, Leverkus, Martin

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Cellular FLICE-inhibitory Protein (cFLIP) Isoforms Block CD95- and TRAIL Death Receptor-induced Gene Induction Irrespective of Processing of Caspase-8 or cFLIP in the Death-inducin... von Kavuri, Shyam M., Geserick, Peter, Berg, Daniela, Dimitrova, Diana Panayotova, Feoktistova, Maria, Siegmund, Daniela, Gollnick, Harald, Neumann, Manfred, Wajant, Harald, Leverkus, Martin

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cFLIP Regulates Skin Homeostasis and Protects against TNF-Induced Keratinocyte Apoptosis von Panayotova-Dimitrova, Diana, Feoktistova, Maria, Ploesser, Michaela, Kellert, Beate, Hupe, Mike, Horn, Sebastian, Makarov, Roman, Jensen, Federico, Porubsky, Stefan, Schmieder, Astrid, Zenclussen, Ana Claudia, Marx, Alexander, Kerstan, Andreas, Geserick, Peter, He, You-Wen, Leverkus, Martin

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On the TRAIL to Overcome BRAF-Inhibitor Resistance von Geserick, Peter, Herlyn, Meenhard, Leverkus, Martin

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Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled von Gnad, Thorsten, Feoktistova, Maria, Leverkus, Martin, Lendeckel, Uwe, Naumann, Michael

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Galli-Galli disease is an acantholytic variant of Dowling-Degos disease: Additional genetic evidence in a German family von Schmieder, Astrid, MD, Pasternack, Sandra M., PhD, Krahl, Dieter, MD, Betz, Regina C., MD, Leverkus, Martin, MD

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Cell Death in the Skin: How to Study Its Quality and Quantity? von Makarov, Roman, Geserick, Peter, Feoktistova, Maria, Leverkus, Martin

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A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes von Feoktistova, Maria, Makarov, Roman, Brenji, Sihem, Schneider, Anne T., Hooiveld, Guido J., Luedde, Tom, Leverkus, Martin, Yazdi, Amir S., Panayotova-Dimitrova, Diana

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