A protein interaction network for pluripotency of embryonic stem cells von Levasseur, Dana N, Rao, Sridhar, Shen, Xiaohua, Orkin, Stuart H, Wang, Jianlong, Chu, Jianlin, Theunissen, Thorold W

Volltext

Alternative Splicing Produces Nanog Protein Variants with Different Capacities for Self-renewal and Pluripotency in Embryonic Stem Cells von Das, Satyabrata, Jena, Snehalata, Levasseur, Dana N.

Volltext

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency von Costa, Yael, Ding, Junjun, Theunissen, Thorold W., Faiola, Francesco, Hore, Timothy A., Shliaha, Pavel V., Fidalgo, Miguel, Saunders, Arven, Lawrence, Moyra, Dietmann, Sabine, Das, Satyabrata, Levasseur, Dana N., Li, Zhe, Xu, Mingjiang, Reik, Wolf, Silva, José C. R., Wang, Jianlong

Volltext

Disruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with β-Thalassemia Major von Psatha, Nikoletta, Reik, Andreas, Phelps, Susan, Zhou, Yuanyue, Dalas, Demetri, Yannaki, Evangelia, Levasseur, Dana N., Urnov, Fyodor D., Holmes, Michael C., Papayannopoulou, Thalia

Volltext

Requirement of Nanog Dimerization for Stem Cell Self-Renewal and Pluripotency von Wang, Jianlong, Levasseur, Dana N., Orkin, Stuart H.

Volltext

Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells von Levasseur, Dana N, Wang, Jianlong, Dorschner, Michael O, Stamatoyannopoulos, John A, Orkin, Stuart H

Volltext

Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease von Li, Xiaopeng, Rossen, Nathan, Sinn, Patrick L, Hornick, Andrew L, Steines, Benjamin R, Karp, Philip H, Ernst, Sarah E, Adam, Ryan J, Moninger, Thomas O, Levasseur, Dana N, Zabner, Joseph

Volltext

Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease von Lessard, Samuel, Rimmelé, Pauline, Ling, Hui, Moran, Kevin, Vieira, Benjamin, Lin, Yi-Dong, Rajani, Gaurav Manohar, Hong, Vu, Reik, Andreas, Boismenu, Richard, Hsu, Ben, Chen, Michael, Cockroft, Bettina M., Uchida, Naoya, Tisdale, John, Alavi, Asif, Krishnamurti, Lakshmanan, Abedi, Mehrdad, Galeon, Isobelle, Reiner, David, Wang, Lin, Ramezi, Anne, Rendo, Pablo, Walters, Mark C., Levasseur, Dana, Peters, Robert, Harris, Timothy, Hicks, Alexandra

Volltext

RARα2 expression confers myeloma stem cell features von Yang, Ye, Shi, Jumei, Tolomelli, Giulia, Xu, Hongwei, Xia, Jiliang, Wang, He, Zhou, Wen, Zhou, Yi, Das, Satyabrata, Gu, Zhimin, Levasseur, Dana, Zhan, Fenghuang, Tricot, Guido

Volltext

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration von Songstad, Allison E, Wiley, Luke A, Duong, Khahn, Kaalberg, Emily, Flamme-Wiese, Miles J, Cranston, Cathryn M, Riker, Megan J, Levasseur, Dana, Stone, Edwin M, Mullins, Robert F, Tucker, Budd A

Volltext

SMARCAD1 Contributes to the Regulation of Naive Pluripotency by Interacting with Histone Citrullination von Xiao, Shu, Lu, Jia, Sridhar, Bharat, Cao, Xiaoyi, Yu, Pengfei, Zhao, Tianyi, Chen, Chieh-Chun, McDee, Darina, Sloofman, Laura, Wang, Yang, Rivas-Astroza, Marcelo, Telugu, Bhanu Prakash V.L., Levasseur, Dana, Zhang, Kang, Liang, Han, Zhao, Jing Crystal, Tanaka, Tetsuya S., Stormo, Gary, Zhong, Sheng

Volltext

Correction of a mouse model of sickle cell disease: lentiviral/antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells von Levasseur, Dana N., Ryan, Thomas M., Pawlik, Kevin M., Townes, Tim M.

Volltext

Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells von Duong, Khanh L, Das, Satyabrata, Yu, Shuyang, Barr, Jennifer Y, Jena, Snehalata, Kim, Eunmi, Zavazava, Nicolas, Colgan, John D, Xue, Hai-Hui, Levasseur, Dana N

Volltext

A Recombinant Human Hemoglobin with Anti-sickling Properties Greater than Fetal Hemoglobin von Levasseur, Dana N., Ryan, Thomas M., Reilly, Michael P., McCune, Steven L., Asakura, Toshio, Townes, Tim M.

Volltext

Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the Escherichia coli purine nucleoside phosphorylase gene von HONG, Jeong S, WAUD, William R, PARKER, William B, SORSCHER, Eric J, LEVASSEUR, Dana N, TOWNES, Tim M, HUI WEN, MCPHERSON, Sylvia A, MOORE, Bryan A, BEBOK, Zsuzsa, ALLAN, Paula W, SECRIST, John A

Volltext

Bruton tyrosine kinase is a therapeutic target in stem-like cells from multiple myeloma von Yang, Ye, Shi, Jumei, Gu, Zhimin, Salama, Mohamed E, Das, Satyabrata, Wendlandt, Erik, Xu, Hongwei, Huang, Junwei, Tao, Yi, Hao, Mu, Franqui, Reinaldo, Levasseur, Dana, Janz, Siegfried, Tricot, Guido, Zhan, Fenghuang

Volltext

ALDH1 activity identifies tumor-initiating cells and links to chromosomal instability signatures in multiple myeloma von Zhou, W, Yang, Y, Gu, Z, Wang, H, Xia, J, Wu, X, Zhan, X, Levasseur, D, Zhou, Y, Janz, S, Tricot, G, Shi, J, Zhan, F

Volltext

Ex Vivo Gene-Edited Cell Therapy for Sickle Cell Disease: Disruption of the BCL11A Erythroid Enhancer with Zinc Finger Nucleases Increases Fetal Hemoglobin in Plerixafor Mobilized... von Moran, Kevin, Ling, Hui, Lessard, Samuel, Vieira, Benjamin, Hong, Vu, Holmes, Michael C., Reik, Andreas, Dang, Denny, Gray, David, Levasseur, Dana, Rimmele, Pauline

Volltext

Complementary Base Editing Approaches for the Treatment of Sickle Cell Disease and Beta Thalassemia von Lin, Ling, Rybak, Adrian P., Rinaldi, Conrad, Yen, Jonathan, Fu, Yanfang, Akrawi, Elsie, Smith, Sarah, Haskett, Scott J., Sanchez, Minerva E., Poh, Yeh-Chuin, Packer, Michael S., Gaudelli, Nicole M., Singh, Manmohan, Ciaramella, Giuseppe, Levasseur, Dana N.

Volltext

Transcriptional Regulatory Mechanisms That Govern Embryonic Stem Cell Fate von Das, Satyabrata, Levasseur, Dana

Volltext