Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding von Gevaert, Thomas, Vriens, Joris, Segal, Andrei, Everaerts, Wouter, Roskams, Tania, Talavera, Karel, Owsianik, Grzegorz, Liedtke, Wolfgang, Daelemans, Dirk, Dewachter, Ilse, Van Leuven, Fred, Voets, Thomas, De Ridder, Dirk, Nilius, Bernd

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Quantitative Assessment of Age-Associated Alterations in Brain Vasculature in Wild-Type Mice and in Bigenic Mice that Model Alzheimer’s Disease von Govaerts, Kristof, Dresselaers, Tom, Van Leuven, Fred, Himmelreich, Uwe

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Positive and negative early life experiences differentially modulate long term survival and amyloid protein levels in a mouse model of Alzheimer's disease von Lesuis, Sylvie L, Maurin, Herve, Borghgraef, Peter, Lucassen, Paul J, Van Leuven, Fred, Krugers, Harm J

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A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease von Van der Auwera, Ingrid, Wera, Stefaan, Van Leuven, Fred, Henderson, Samuel T

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Synaptic dysfunction in hippocampus of transgenic mouse models of Alzheimer's disease: A multi-electrode array study von Chong, Seon-Ah, Benilova, Iryna, Shaban, Hamdy, De Strooper, Bart, Devijver, Herman, Moechars, Dieder, Eberle, Wolfgang, Bartic, Carmen, Van Leuven, Fred, Callewaert, Geert

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Phosphorylation of protein Tau by GSK3β prolongs survival of bigenic Tau.P301L × GSK3β mice by delaying brainstem tauopathy von Crespo-Biel, Natalia, Theunis, Clara, Borghgraef, Peter, Lechat, Benoit, Devijver, Herman, Maurin, Hervé, Van Leuven, Fred

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Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes von Pajares, Marta, Jiménez-Moreno, Natalia, García-Yagüe, Ángel J., Escoll, Maribel, de Ceballos, María L., Van Leuven, Fred, Rábano, Alberto, Yamamoto, Masayuki, Rojo, Ana I., Cuadrado, Antonio

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Neuropeptide pituitary adenylate cyclase‐activating polypeptide (PACAP) slows down Alzheimer's disease‐like pathology in amyloid precursor protein‐transgenic mice von Rat, Dorothea, Schmitt, Ulrich, Tippmann, Frank, Dewachter, Ilse, Theunis, Clara, Wieczerzak, Ewa, Postina, Rolf, Leuven, Fred, Fahrenholz, Falk, Kojro, Elzbieta

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NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology von Rojo, Ana I., Pajares, Marta, Rada, Patricia, Nuñez, Angel, Nevado-Holgado, Alejo J., Killik, Richard, Van Leuven, Fred, Ribe, Elena, Lovestone, Simon, Yamamoto, Masayuki, Cuadrado, Antonio

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Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis von LASTRES-BECKER, Isabel, INNAMORATO, Nadia G, JAWORSKI, Tomasz, RABANO, Alberto, KÜGLER, Sebastian, VAN LEUVEN, Fred, CUADRADO, Antonio

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Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein von Parr, Callum, Carzaniga, Raffaela, Gentleman, Steve M., Van Leuven, Fred, Walter, Jochen, Sastre, Magdalena

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Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis von Rada, Patricia, Rojo, Ana I., Evrard-Todeschi, Nathalie, Innamorato, Nadia G., Cotte, Axelle, Jaworski, Tomasz, Tobón-Velasco, Julio C., Devijver, Herman, García-Mayoral, María Flor, Van Leuven, Fred, Hayes, John D., Bertho, Gildas, Cuadrado, Antonio

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Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy von Theunis, Clara, Crespo-Biel, Natalia, Gafner, Valérie, Pihlgren, Maria, López-Deber, María Pilar, Reis, Pedro, Hickman, David T, Adolfsson, Oskar, Chuard, Nathalie, Ndao, Dorin Mlaki, Borghgraef, Peter, Devijver, Herman, Van Leuven, Fred, Pfeifer, Andrea, Muhs, Andreas

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Dendritic Degeneration, Neurovascular Defects, and Inflammation Precede Neuronal Loss in a Mouse Model for Tau-Mediated Neurodegeneration von Jaworski, Tomasz, Lechat, Benoit, Demedts, David, Gielis, Lies, Devijver, Herman, Borghgraef, Peter, Duimel, Hans, Verheyen, Fons, Kügler, Sebastian, Van Leuven, Fred

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Longitudinal assessment of cerebral perfusion and vascular response to hypoventilation in a bigenic mouse model of Alzheimer's disease with amyloid and tau pathology von Govaerts, Kristof, Lechat, Benoit, Struys, Tom, Kremer, Anna, Borghgraef, Peter, Van Leuven, Fred, Himmelreich, Uwe, Dresselaers, Tom

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Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy von Rojo, Ana I., Pajares, Marta, García-Yagüe, Angel J., Buendia, Izaskun, Van Leuven, Fred, Yamamoto, Masayuki, López, Manuela G., Cuadrado, Antonio

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The Capsaicin Receptor TRPV1 Is a Crucial Mediator of the Noxious Effects of Mustard Oil von Everaerts, Wouter, Gees, Maarten, Alpizar, Yeranddy A., Farre, Ricard, Leten, Cindy, Apetrei, Aurelia, Dewachter, Ilse, van Leuven, Fred, Vennekens, Rudi, De Ridder, Dirk, Nilius, Bernd, Voets, Thomas, Talavera, Karel

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Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease von Jaworski, Tomasz, Kügler, Sebastian, Van Leuven, Fred

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GSK3β Controls mTOR and Prosurvival Signaling in Neurons von Urbanska, Malgorzata, Gozdz, Agata, Macias, Matylda, Cymerman, Iwona A., Liszewska, Ewa, Kondratiuk, Ilona, Devijver, Herman, Lechat, Benoit, Van Leuven, Fred, Jaworski, Jacek

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Regional vulnerability and spreading of hyperphosphorylated tau in seeded mouse brain von Detrez, Jan R., Maurin, Hervé, Van Kolen, Kristof, Willems, Roland, Colombelli, Julien, Lechat, Benoit, Roucourt, Bart, Van Leuven, Fred, Baatout, Sarah, Larsen, Peter, Nuydens, Rony, Timmermans, Jean-Pierre, De Vos, Winnok H.

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