Versatile Synthetic Approach for Selective Diversification of Bicyclic Aza-Diketopiperazines von Péron, Florent, Riché, Stéphanie, Lesur, Brigitte, Hibert, Marcel, Breton, Philippe, Fourquez, Jean-Marie, Girard, Nicolas, Bonnet, Dominique

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Productive Syntheses of Privileged Scaffolds Inspired by the Recognition of a Diels–Alder Pattern Common to Three Classes of Natural Products von Badarau, Eduard, Reddy, K. Harsha Vardhan, Loudet, Aurore, Simon, Charles, Trembleau, Laurent, Claerhout, Stijn, Pair, Etienne, Massip, Stéphane, Breton, Philippe, Lesur, Brigitte, Goldstein, Solo, Fourquez, Jean‐Marie, Henlin, Jean Michel, Ghosez, Léon

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IMI European Lead Factory — democratizing access to high-throughput screening von Jones, Philip S., Boucharens, Sylviane, McElroy, Stuart P., Morrison, Angus, Honarnejad, Saman, van Boeckel, Stan, van den Hurk, Helma, Basting, Daniel, Hüser, Jörg, Jaroch, Stefan, Ottow, Eckhard, Benningshof, Jorg, Folmer, Rutger H. A., Leemhuis, Frank, Kramer-Verhulst, Patricia M., Nies, Vera J. M., Orrling, Kristina M., Rijnders, Ton, Pfander, Claudia, Engkvist, Ola, Pairaudeau, Garry, Simpson, Peter B., Ortholand, Jean-Yves, Roche, Didier, Dömling, Alexander, Kühnert, Sven M., Roevens, Peter W. M., van Vlijmen, Herman, van Wanrooij, Eva J. A., Verbruggen, Christophe, Nussbaumer, Peter, Ovaa, Huib, van der Stelt, Mario, Simonsen, Klaus Baek, Tagmose, Lena, Waldmann, Herbert, Duffy, James, Finsinger, Dirk, Jurzak, Mirek, Burgess-Brown, Nicola A., Lee, Wen H., Rutjes, Floris P. J. T., Haag, Hubert, Kallus, Christopher, Mors, Hartmut, Dorval, Thierry, Lesur, Brigitte, Ramon Olayo, Fernando, Hamza, Daniel, Jones, Geraint, Pearce, Christopher, Piechot, Alexander, Tzalis, Dimitrios, Clausen, Mads H., Davis, Jeremy, Derouane, Daphné, Vermeiren, Céline, Kaiser, Markus, Stockman, Robert A., Barrault, Denise V., Pannifer, Andrew D., Swedlow, Jason R., Nelson, Adam S., Orru, Romano V. A., Ruijter, Eelco, van Helden, Steven P., Li, Volkhart M., Vries, Ton, de Vlieger, Jon S. B.

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Convenient Synthetic Routesto 5-Substituted 3-(4-Methoxyphenyl)-4(1 H )-quinolones von Joseph, Benoît, Béhard, Aurélie, Lesur, Brigitte, Guillaumet, Gérald

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Hit finding: towards ‘smarter’ approaches von Langer, Thierry, Hoffmann, Rémy, Bryant, Sharon, Lesur, Brigitte

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Synthesis and Antitumor Characterization of Pyrazolic Analogues of the Marine Pyrroloquinoline Alkaloids: Wakayin and Tsitsikammamines von Legentil, Laurent, Benel, Laurent, Bertrand, Viviane, Lesur, Brigitte, Delfourne, Evelyne

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3-Aryl-2-Quinolone Derivatives:  Synthesis and Characterization of In Vitro and In Vivo Antitumor Effects with Emphasis on a New Therapeutical Target Connected with Cell Migration... von Joseph, Benoît, Darro, Francis, Béhard, Aurélie, Lesur, Brigitte, Collignon, Françoise, Decaestecker, Christine, Frydman, Armand, Guillaumet, Gérald, Kiss, Robert

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A convenient synthesis of 5-arylamino-4H-pyran-4-ones using palladium-catalyzed amination von Farard, Julien, Logé, Cédric, Pfeiffer, Bruno, Lesur, Brigitte, Duflos, Muriel

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Aza-analogues of the marine pyrroloquinoline alkaloids wakayin and tsitsikammamines: Synthesis and topoisomerase inhibition von Legentil, Laurent, Lesur, Brigitte, Delfourne, Evelyne

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A convenient synthesis of 5-arylamino-4 H-pyran-4-ones using palladium-catalyzed amination von Farard, Julien, Logé, Cédric, Pfeiffer, Bruno, Lesur, Brigitte, Duflos, Muriel

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A highly stereoselective synthesis of (+)-olivin, the aglycon of olivomycin A von Roush, William R, Michaelides, Michael R, Tai, Dar Fu, Lesur, Brigitte M, Chong, Wesley K. M, Harris, David J

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Wake-promoting agents: Search for next generation modafinil: Part IV von Louvet, Philippe, Schweizer, Dominique, Gourdel, Marie-Edith, Riguet, Eric, Yue, Christoph, Marcy, Val R., Lin, Yin Guo, Gruner, John, Lesur, Brigitte, Bacon, Edward R., Chatterjee, Sankar

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Novel morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activity von Sundar, Babu G., Bailey, Thomas R., Dunn, Derek, Hostetler, Greg A., Chatterjee, Sankar, Bacon, Edward R., Yue, Christoph, Schweizer, Dominique, Aimone, Lisa D., Gruner, John A., Lyons, Jacquelyn, Raddatz, Rita, Lesur, Brigitte

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Aryl-Heteroaryl Derivatives as Novel Wake-Promoting Agents von Lesur, Brigitte, Lin, Yin G., Marcy, Val R., Aimone, Lisa D., Gruner, John, Bacon, Edward R., Chatterjee, Sankar

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Chemoinformatics and virtual screening of molecules for therapeutic use von Vayer, Philippe, Arrault, Alban, Lesur, Brigitte, Bertrand, Marc, Walther, Bernard

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Synthesis and in vitro antitumor activity of ring C and D-substituted phenanthrolin-7-one derivatives, analogues of the marine pyridoacridine alkaloids ascididemin and meridine von Delfourne, Evelyne, Kiss, Robert, Le Corre, Laurent, Dujols, Frederic, Bastide, Jean, Collignon, Françoise, Lesur, Brigitte, Frydman, Armand, Darro, Francis

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Convenient Synthetic Routes to 5-Substituted 3-(4-Methoxyphenyl)-4(1H)-quinolones von Joseph, Benoît, Béhard, Aurélie, Lesur, Brigitte, Guillaumet, Gérald

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Synthesis and in Vitro Antitumor Activity of Phenanthrolin-7-one Derivatives, Analogues of the Marine Pyridoacridine Alkaloids Ascididemin and Meridine: Structure−Activity Relation... von Delfourne, Evelyne, Kiss, Robert, Corre, Laurent Le, Dujols, Frederic, Bastide, Jean, Collignon, Françoise, Lesur, Brigitte, Frydman, Armand, Darro, Francis

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Synthesis and In Vitro Antitumor Activity of Novel Ring D Analogues of the Marine Pyridoacridine Ascididemin: Structure−Activity Relationship von Delfourne, Evelyne, Darro, Francis, Portefaix, Philippe, Galaup, Chantal, Bayssade, Sylvie, Bouteillé, Anne, Le Corre, Laurent, Bastide, Jean, Collignon, Françoise, Lesur, Brigitte, Frydman, Armand, Kiss, Robert

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Apports de la chémo-informatique dans la recherche et l’optimisation des molécules d’intérêt thérapeutique von Vayer, Philippe, Arrault, Alban, Lesur, Brigitte, Bertrand, Marc, Walther, Bernard

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