Dynamic versus static biomarkers in cancer immune checkpoint blockade: unravelling complexity von Lesterhuis, W. Joost, Bosco, Anthony, Millward, Michael J., Small, Michael, Nowak, Anna K., Lake, Richard A.

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Molecular Pathways: The Immunogenic Effects of Platinum-Based Chemotherapeutics von HATO, Stanleyson V, KHONG, Andrea, DE VRIES, I. Jolanda M, LESTERHUIS, W. Joost

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A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice von Aston, Wayne J, Hope, Danika E, Nowak, Anna K, Robinson, Bruce W, Lake, Richard A, Lesterhuis, W Joost

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Chemotherapy and immunotherapy: mapping the road ahead von Cook, Alistair M, Lesterhuis, W Joost, Nowak, Anna K, Lake, Richard A

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Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity von Lesterhuis, W Joost, Salmons, Joanne, Nowak, Anna K, Rozali, Esdy N, Khong, Andrea, Dick, Ian M, Harken, Julie A, Robinson, Bruce W, Lake, Richard A

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Cancer chemotherapy: insights into cellular and tumor microenvironmental mechanisms of action von Tilsed, Caitlin M., Fisher, Scott A., Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost

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Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice von Zemek, Rachael M., Chin, Wee Loong, Fear, Vanessa S., Wylie, Ben, Casey, Thomas H., Forbes, Cath, Tilsed, Caitlin M., Boon, Louis, Guo, Belinda B., Bosco, Anthony, Forrest, Alistair R. R., Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lassmann, Timo, Lesterhuis, W. Joost

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Bilateral murine tumor models for characterizing the response to immune checkpoint blockade von Zemek, Rachael M., Fear, Vanessa S., Forbes, Cath, de Jong, Emma, Casey, Thomas H., Boon, Louis, Lassmann, Timo, Bosco, Anthony, Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost

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Combination immune checkpoint blockade as an effective therapy for mesothelioma von Fear, Vanessa S., Tilsed, Caitlin, Chee, Jonathan, Forbes, Catherine A., Casey, Thomas, Solin, Jessica N., Lansley, Sally M., Lesterhuis, Willem Joost, Dick, Ian M., Nowak, Anna K, Robinson, Bruce W., Lake, Richard A., Fisher, Scott A.

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Programmed Death Ligand 2 in Cancer-Induced Immune Suppression von Lake, Richard A., Robinson, Bruce W. S., Hato, Stanleyson V., Rozali, Esdy N., Lesterhuis, W. Joost

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Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy von Zemek, Rachael M, Chin, Wee Loong, Nowak, Anna K, Millward, Michael J, Lake, Richard A, Lesterhuis, W Joost

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Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma von Orozco Morales, M Lizeth, Rinaldi, Catherine A, de Jong, Emma, Lansley, Sally M, Lee, Y C Gary, Zemek, Rachael M, Bosco, Anthony, Lake, Richard A, Lesterhuis, W Joost

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Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell―Based Vaccination von AARNTZEN, Erik H. J. G, DE VRIES, I. Jolanda M, SCHADENDORF, Dirk, CROOCKEWIT, Alexandra, BLOKX, Willeke A. M, VAN ROSSUM, Michelle M, KWOK, William W, ADEMA, Gosse J, PUNT, Cornelis J. A, FIGDOR, Carl G, JOOST LESTERHUIS, W, SCHUURHUIS, Danita, JACOBS, JoannesF. M, BOL, Kalijn, SCHREIBELT, Gerty, MUS, Roel, DE WILT, Johannes H. W, HAANEN, John B. A. G

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Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial von Boudewijns, Steve, Bloemendal, Martine, de Haas, Nienke, Westdorp, Harm, Bol, Kalijn F., Schreibelt, Gerty, Aarntzen, Erik H. J. G., Lesterhuis, W. Joost, Gorris, Mark A. J., Croockewit, Alexandra, van der Woude, Lieke L., van Rossum, Michelle M., Welzen, Marieke, de Goede, Anna, Hato, Stanleyson V., van der Graaf, Winette T. A., Punt, Cornelis J. A., Koornstra, Rutger H. T., Gerritsen, Winald R., Figdor, Carl G., de Vries, I. Jolanda M.

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Route of Administration Modulates the Induction of Dendritic Cell Vaccine―Induced Antigen-Specific T Cells in Advanced Melanoma Patients von JOOST LESTERHUIS, W, DE VRIES, I. Jolanda M, VAN ROSSUM, Michelle M, MUS, Roel, OYEN, Wim J. G, BOERMAN, Otto C, LUCAS, Sophie, ADEMA, Gosse J, PUNT, Cornelis J. A, FIGDOR, Carl G, SCHREIBELT, Gerty, LAMBECK, Annechien J. A, AARNTZEN, Erik H. J. G, JACOBS, Joannes F. M, SCHARENBORG, Nicole M, VAN DE RAKT, Mandy W. M. M, DE BOER, Annemiek J, CROOCKEWIT, Sandra

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Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy von Bulte, Jeff W M, Figdor, Carl G, de Vries, I Jolanda M, Lesterhuis, W Joost, Barentsz, Jelle O, Verdijk, Pauline, van Krieken, J Han, Boerman, Otto C, Oyen, Wim J G, Bonenkamp, Johannes J, Boezeman, Jan B, Adema, Gosse J, Scheenen, Tom W J, Punt, Cornelis J A, Heerschap, Arend

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Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner von Tilsed, Caitlin M, Morales, M Lizeth Orozco, Zemek, Rachael M, Gordon, Brianna A, Piggott, Matthew J, Nowak, Anna K, Fisher, Scott A, Lake, Richard A, Lesterhuis, W Joost

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Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell―Based Vaccination in Metastatic Melanoma von AARNTZEN, Erik H. J. G, BOL, Kalijn, SCHREIBELT, Gerty, JACOBS, Joannes F. M, JOOST LESTERHUIS, W, VAN ROSSUM, Michelle M, ADEMA, Gosse J, FIGDOR, Carl G, PUNT, Cornelis J. A, DE VRIES, I. Jolanda M

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Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment von Aston, Wayne J., Hope, Danika E., Cook, Alistair M., Boon, Louis, Dick, Ian, Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost

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Local therapy with combination TLR agonists stimulates systemic anti-tumor immunity and sensitizes tumors to immune checkpoint blockade von Rwandamuriye, Francois Xavier, Wang, Tao, Zhang, Hanfu, Elaskalani, Omar, Kuster, Jorren, Ye, Xueting, Vitali, Breana, Schreurs, Juliët, Orozco Morales, M. Lizeth, Norret, Marck, Evans, Cameron W., Zemek, Rachael M., Iyer, K. Swaminathan, Lesterhuis, W. Joost, Wylie, Ben

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