Chemotherapy in localized soft tissue sarcoma: will we soon have to treat grade 1 tumors? Update on CINSARC performances von Valentin, T., Lesluyes, T., Le Guellec, S., Chibon, F.

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Specific immune landscapes and immune checkpoint expressions in histotypes and molecular subtypes of sarcoma von Dufresne, A., Lesluyes, T., Ménétrier-Caux, C., Brahmi, M., Darbo, E., Toulmonde, M., Italiano, A., Mir, O., Le Cesne, A., Le Guellec, S., Valentin, T., Chevreau, C., Bonvalot, S., Robin, Y.M., Coindre, J-M, Caux, C., Blay, J.Y., Chibon, F.

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Validation of the Complexity INdex in SARComas prognostic signature on formalin-fixed, paraffin-embedded, soft-tissue sarcomas von Le Guellec, S., Lesluyes, T., Sarot, E., Valle, C., Filleron, T., Rochaix, P., Valentin, T., Pérot, G., Coindre, J.-M., Chibon, F.

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The emerging role of ATRX and chromatin remodeling in pleomorphic sarcomas oncogenesis von Michaud, M, Pérot, G, Lesluyes, T, Desplat, N, Delespaul, L, Lucchesi, C, Neuville, A, Blay, J.Y, Coindre, J.M, Chibon, F

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Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas von Brahmi, M., Lesluyes, T., Dufresne, A., Toulmonde, M., Italiano, A., Mir, O., Le Cesne, A., Valentin, T., Chevreau, C., Bonvalot, S., Penel, N., Coindre, J.-M., Le Guellec, S., Le Loarer, F., Karanian, M., Blay, J.-Y., Chibon, F.

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Fusion of immortalized myoblasts induces genomic instability that drives tumour development and progression von Merle, C., Baud, J., Thebaud, N., Lesluyes, T., Pérot, G., Delespaul, L., Lartigue, L., Chibon, F.

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1719PFusion of immortalized myoblasts induces genomic instability that drives tumour development and progression von Merle, C, Baud, J, Thebaud, N, Lesluyes, T, Pérot, G, Delespaul, L, Lartigue, L, Chibon, F

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1719P - Fusion of immortalized myoblasts induces genomic instability that drives tumour development and progression von Merle, C., Baud, J., Thebaud, N., Lesluyes, T., Pérot, G., Delespaul, L., Lartigue, L., Chibon, F.

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2236P MHC-II neoantigens and copy number alterations (CNA) drive immune checkpoint inhibitor (ICI) response in metastatic melanoma (MM) von Shum, B., Lobon, I., Lesluyes, T., Pallikonda, H., Khoja, L.T., Kissoonsingh, P., Nahm, S.H., El Badri, S., Peleva, E., Fusi, A., Gault, A.C., Marais, R., Dhomen, N., Arumugam, P., Pickering, L.M., Danson, S., Larkin, J., Litchfield, K.R., Lorigan, P., Turajlic, S.

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The Role of the Anti-Aging Protein Klotho in IGF-1 Signaling and Reticular Calcium Leak: Impact on the Chemosensitivity of Dedifferentiated Liposarcomas von Delcroix, Vanessa, Mauduit, Olivier, Tessier, Nolwenn, Montillaud, Anaïs, Lesluyes, Tom, Ducret, Thomas, Chibon, Frédéric, Van Coppenolle, Fabien, Ducreux, Sylvie, Vacher, Pierre

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169 - The emerging role of ATRX and chromatin remodeling in pleomorphic sarcomas oncogenesis von Michaud, M., Pérot, G., Lesluyes, T., Desplat, N., Delespaul, L., Lucchesi, C., Neuville, A., Blay, J.Y., Coindre, J.M., Chibon, F.

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14P Integrated genomic analysis of whole genomes to derive a biomarker of durable response to immunotherapy in melanoma von Lobon, I., Shum, B., Egan, D., Fidan, R., Lesluyes, T., Jiang, Q., Pallikonda, H., Khoja, L., Nahm, S.H., El Badri, S., Peleva, E., Fusi, A., Gault, A.C., Pickering, L.M., Danson, S., van Loo, P., Litchfield, K.R., Larkin, J., Lorigan, P., Turajlic, S.

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CINSARC in high-risk soft tissue sarcoma patients treated with neoadjuvant chemotherapy : Results from the ISG-STS 1001 study von Frezza, Anna Maria, Stacchiotti, Silvia, Chibon, F, Coindre, J.M, Italiano, A, Romagnosa, Cleofe, Bagué Rosell, Sílvia, Dei Tos, A.P, Braglia, L, Palmerini, E, Quagliuolo, V, Broto, J.M, López Pousa, Antonio, Grignani, Giovanni, Brunello, A, Blay, J.Y, Beveridge, R.D, Lugowska, I, Lesluyes, T, Maestro, R, Merlo, F.D, Casali, P.G, Gronchi, A, Universitat Autònoma de Barcelona

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An integrative analysis of the age-associated multi-omic landscape across cancers von Chatsirisupachai, Kasit, Lesluyes, Tom, Paraoan, Luminita, Van Loo, Peter, de Magalhães, João Pedro

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Signatures of copy number alterations in human cancer von Steele, Christopher D., Abbasi, Ammal, Islam, S. M. Ashiqul, Bowes, Amy L., Khandekar, Azhar, Haase, Kerstin, Hames-Fathi, Shadi, Ajayi, Dolapo, Verfaillie, Annelien, Dhami, Pawan, McLatchie, Alex, Lechner, Matt, Light, Nicholas, Shlien, Adam, Malkin, David, Feber, Andrew, Proszek, Paula, Lesluyes, Tom, Mertens, Fredrik, Flanagan, Adrienne M., Tarabichi, Maxime, Van Loo, Peter, Alexandrov, Ludmil B., Pillay, Nischalan

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A Global and Integrated Analysis of CINSARC-Associated Genetic Defects von Lesluyes, Tom, Chibon, Frédéric

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Cell–cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness von Delespaul, Lucile, Gélabert, Caroline, Lesluyes, Tom, Le Guellec, Sophie, Pérot, Gaëlle, Leroy, Laura, Baud, Jessica, Merle, Candice, Lartigue, Lydia, Chibon, Frédéric

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CINSARC signature as a prognostic marker for clinical outcome in sarcomas and beyond von Chibon, Frederic, Lesluyes, Tom, Valentin, Thibaud, Le Guellec, Sophie

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Recurrent TRIO Fusion in Nontranslocation-Related Sarcomas von Delespaul, Lucile, Lesluyes, Tom, Pérot, Gaëlle, Brulard, Céline, Lartigue, Lydia, Baud, Jessica, Lagarde, Pauline, Le Guellec, Sophie, Neuville, Agnès, Terrier, Philippe, Vince-Ranchère, Dominique, Schmidt, Susanne, Debant, Anne, Coindre, Jean-Michel, Chibon, Frédéric

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A pan-cancer compendium of chromosomal instability von Drews, Ruben M., Hernando, Barbara, Tarabichi, Maxime, Haase, Kerstin, Lesluyes, Tom, Smith, Philip S., Morrill Gavarró, Lena, Couturier, Dominique-Laurent, Liu, Lydia, Schneider, Michael, Brenton, James D., Van Loo, Peter, Macintyre, Geoff, Markowetz, Florian

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