Oral antibiotic use and early-onset colorectal cancer: findings from a case-control study using a national clinical database von McDowell, Ronald, Perrott, Sarah, Murchie, Peter, Cardwell, Christopher, Hughes, Carmel, Samuel, Leslie

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Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning von Sirinukunwattana, Korsuk, Domingo, Enric, Richman, Susan D, Redmond, Keara L, Blake, Andrew, Verrill, Clare, Leedham, Simon J, Chatzipli, Aikaterini, Hardy, Claire, Whalley, Celina M, Wu, Chieh-hsi, Beggs, Andrew D, McDermott, Ultan, Dunne, Philip D, Meade, Angela, Walker, Steven M, Murray, Graeme I, Samuel, Leslie, Seymour, Matthew, Tomlinson, Ian, Quirke, Phil, Maughan, Timothy, Rittscher, Jens, Koelzer, Viktor H

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Young-onset colorectal cancer in the North East of Scotland: survival, clinico-pathological features and genetics von Perrott, Sarah, Laurie, Kirsten, Laws, Kirsten, Johnes, Annie, Miedzybrodzka, Zosia, Samuel, Leslie

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Pathological response post neoadjuvant therapy for locally advanced rectal cancer is an independent predictor of survival von On, Jason, Shim, Joanna, Mackay, Craig, Murray, Graeme, Samuel, Leslie, Parnaby, Craig, Ramsay, George

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Stochastic Pharmacokinetic-Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA) von Convertino, Matteo, Church, Timothy R, Olsen, Geary W, Liu, Yang, Doyle, Eddie, Elcombe, Clifford R, Barnett, Anna L, Samuel, Leslie M, MacPherson, Iain R, Evans, Thomas R J

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Markers of low field NMR relaxation features of tissues von Kołodziejski, Karol, Masiewicz, Elzbieta, Alamri, Amnah, Zampetoulas, Vasileios, Samuel, Leslie, Murray, Graeme, Lurie, David J., Broche, Lionel M., Kruk, Danuta

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Phase II Study of the Dual EGFR/HER3 Inhibitor Duligotuzumab (MEHD7945A) versus Cetuximab in Combination with FOLFIRI in Second-Line RAS Wild-Type Metastatic Colorectal Cancer von Hill, Andrew G, Findlay, Michael P, Burge, Matthew E, Jackson, Christopher, Alfonso, Pilar Garcia, Samuel, Leslie, Ganju, Vinod, Karthaus, Meinolf, Amatu, Alessio, Jeffery, Mark, Bartolomeo, Maria Di, Bridgewater, John, Coveler, Andrew L, Hidalgo, Manuel, Kapp, Amy V, Sufan, Roxana I, McCall, Bruce B, Hanley, William D, Penuel, Elicia M, Pirzkall, Andrea, Tabernero, Josep

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Randomized Controlled Clinical Effectiveness Trial of Cognitive Behavior Therapy Compared With Treatment As Usual for Persistent Insomnia in Patients With Cancer von ESPIE, Colin A, FLEMING, Leanne, CASSIDY, James, SAMUEL, Leslie, TAYLOR, Lynne M, WHITE, Craig A, DOUGLAS, Neil J, ENGLEMAN, Heather M, KELLY, Heidi-Louise, PAUL, James

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Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis von Schoenpflug, Lydia A, Chatzipli, Aikaterini, Sirinukunwattana, Korsuk, Richman, Susan, Blake, Andrew, Robineau, James, Mertz, Kirsten D, Verrill, Clare, Leedham, Simon J, Hardy, Claire, Whalley, Celina, Redmond, Keara, Dunne, Philip, Walker, Steven, Beggs, Andrew D, McDermott, Ultan, Murray, Graeme I, Samuel, Leslie M, Seymour, Matthew, Tomlinson, Ian, Quirke, Philip, Adams, Richard, Youdell, Michael, Koelzer, Viktor, Bach, Simon, Beggs, Andrew, Whalley, Celina, Brown, Louise, Buffa, Francesca, Campbell, Peter, Cazier, Jean‐Baptiste, Domingo, Enric, Blake, Andrew, Wu, Chieh‐His, Chatzipli, Aikaterini, Hardy, Claire, Richman, Susan, Dunne, Philip, Redmond, Keara, Harkin, Paul, Walker, Steven, Higgins, Geoff, Hill, Jim, Holmes, Chris, Horgan, Denis, Kaplan, Rick, Kennedy, Richard, Lawler, Mark, Leedham, Simon, Maughan, Tim, McDermott, Ultan, McKenna, Gillies, Middleton, Gary, Morton, Dion, Murray, Graeme, Quirke, Phil, Rathee, Sanjay, Robineau, James, Salto‐Tellez, Manuel, Samuel, Les, Schuh, Anna, Sebag‐Montefiore, David, Seymour, Matt, Sharma, Ricky, Sullivan, Richard, Tomlinson, Ian, West, Nicholas, Wilson, Richard, Rittscher, Jens, Maughan, Tim, Domingo, Enric, Koelzer, Viktor H

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Case Report: Management of an Elderly Patient With Metastatic Radioiodine-Resistant Differentiated Thyroid Cancer in a Rural Community, Remote From Specialist Oncology Services von Wybrew, Rachael, Loynd, Michael, Wybrew, Maria, Samuel, Leslie

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Increased lymph node yield in colorectal cancer is not necessarily associated with a greater number of lymph node positive cancers von O'Shea, Aisling, Aly, Omar, Parnaby, Craig N, Loudon, Malcolm A, Samuel, Leslie M, Murray, Graeme I

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Durvalumab (MEDI 4736) in combination with extended neoadjuvant regimens in rectal cancer: a study protocol of a randomised phase II trial (PRIME-RT) von Hanna, Catherine R, O'Cathail, Sean M, Graham, Janet S, Saunders, Mark, Samuel, Leslie, Harrison, Mark, Devlin, Lynsey, Edwards, Joanne, Gaya, Daniel R, Kelly, Caroline A, Lewsley, Liz-Anne, Maka, Noori, Morrison, Paula, Dinnett, Louise, Dillon, Susan, Gourlay, Jacqueline, Platt, Jonathan J, Thomson, Fiona, Adams, Richard A, Roxburgh, Campbell S D

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Toward shared care for people with cancer: developing the model with patients and GPs von Hall, Susan J, Samuel, Leslie M, Murchie, Peter

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The expression and prognostic significance of bcl-2-associated transcription factor 1 in rectal cancer following neoadjuvant therapy von Brown, Gordon T, Cash, Beatriz, Alnabulsi, Ayham, Samuel, Leslie M, Murray, Graeme I

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Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer von Brown, Louise C, Graham, Janet, Fisher, David, Adams, Richard, Seligmann, Jenny, Seymour, Matthew, Kaplan, Richard, Yates, Emma, Parmar, Mahesh, Richman, Susan D, Quirke, Philip, Butler, Rachel, Shiu, Kaikeen, Middleton, Gary, Samuel, Leslie, Wilson, Richard H, Maughan, Timothy S

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Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival von Alderdice, Matthew, Dunne, Philip D, Cole, Aidan J, O’Reilly, Paul G, McArt, Darragh G, Bingham, Vicky, Fuchs, Marc-Aurel, McQuaid, Stephen, Loughrey, Maurice B, Murray, Graeme I, Samuel, Leslie M, Lawler, Mark, Wilson, Richard H, Salto-Tellez, Manuel, Coyle, Vicky M

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Correction to: Durvalumab (MEDI 4736) in combination with extended neoadjuvant regimens in rectal cancer: a study protocol of a randomised phase II trial (PRIME-RT) von Hanna, Catherine R, O'Cathail, Sean M, Graham, Janet S, Saunders, Mark, Samuel, Leslie, Harrison, Mark, Devlin, Lynsey, Edwards, Joanne, Gaya, Daniel R, Kelly, Caroline A, Lewsley, Liz-Anne, Maka, Noori, Morrison, Paula, Dinnett, Louise, Dillon, Susan, Gourlay, Jacqueline, Platt, Jonathan J, Thomson, Fiona, Adams, Richard A, Roxburgh, Campbell S D

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Randomized study of etirinotecan pegol versus irinotecan as second-line treatment for metastatic colorectal cancer von Lenz, Heinz-Josef, Philip, Philip, Saunders, Mark, Kolevska, Tatjana, Mukherjee, Kalyan, Samuel, Leslie, Bondarde, Shailesh, Dobbs, Tracy, Tagliaferri, Mary, Hoch, Ute, Hannah, Alison L., Berkowitz, Maurice

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APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling von Petty, Russell D, Samuel, Leslie M, Murray, Graeme I, MacDonald, Graham, O'Kelly, Terrence, Loudon, Malcolm, Binnie, Norman, Aly, Emad, McKinlay, Aileen, Wang, Weiguang, Gilbert, Fiona, Semple, Scot, Collie-Duguid, Elaina S R

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Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy von Lafarge, Maxime W., Domingo, Enric, Sirinukunwattana, Korsuk, Wood, Ruby, Samuel, Leslie, Murray, Graeme, Richman, Susan D., Blake, Andrew, Sebag-Montefiore, David, Gollins, Simon, Klieser, Eckhard, Neureiter, Daniel, Huemer, Florian, Greil, Richard, Dunne, Philip, Quirke, Philip, Weiss, Lukas, Rittscher, Jens, Maughan, Tim, Koelzer, Viktor H.

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