Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells von Takeishi, Kazuki, Collin de l’Hortet, Alexandra, Wang, Yang, Handa, Kan, Guzman-Lepe, Jorge, Matsubara, Kentaro, Morita, Kazutoyo, Jang, Sae, Haep, Nils, Florentino, Rodrigo M., Yuan, Fangchao, Fukumitsu, Ken, Tobita, Kimimasa, Sun, Wendell, Franks, Jonathan, Delgado, Evan R., Shapiro, Erik M., Fraunhoffer, Nicolas A., Duncan, Andrew W., Yagi, Hiroshi, Mashimo, Tomoji, Fox, Ira J., Soto-Gutierrez, Alejandro

Volltext

Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver‐Enriched Transcription Factors and Functional Proteins in End‐Stage Cirrhotic Human Hepatocytes von Tafaleng, Edgar N., Mukherjee, Amitava, Bell, Aaron, Morita, Kazutoyo, Guzman‐Lepe, Jorge, Haep, Nils, Florentino, Rodrigo M., Diaz‐Aragon, Ricardo, Frau, Carla, Ostrowska, Alina, Schultz, Joshua R., Martini, Paolo G. V., Soto‐Gutierrez, Alejandro, Fox, Ira J.

Volltext

Liver‐enriched transcription factor expression relates to chronic hepatic failure in humans von Guzman‐Lepe, Jorge, Cervantes‐Alvarez, Eduardo, Collin de l'Hortet, Alexandra, Wang, Yang, Mars, Wendy M., Oda, Yoshinao, Bekki, Yuki, Shimokawa, Masahiro, Wang, Huanlin, Yoshizumi, Tomoharu, Maehara, Yoshihiko, Bell, Aaron, Fox, Ira J., Takeishi, Kazuki, Soto‐Gutierrez, Alejandro

Volltext

SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids von Tobita, Takamasa, Guzman-Lepe, Jorge, Takeishi, Kazuki, Nakao, Toshimasa, Wang, Yang, Meng, Fanying, Deng, Chu-Xia, Collin de l'Hortet, Alexandra, Soto-Gutierrez, Alejandro

Volltext

Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans von Florentino, Rodrigo M., Fraunhoffer, Nicolas A., Morita, Kazutoyo, Takeishi, Kazuki, Ostrowska, Alina, Achreja, Abhinav, Animasahun, Olamide, Haep, Nils, Arazov, Shohrat, Agarwal, Nandini, Collin de l'Hortet, Alexandra, Guzman‐Lepe, Jorge, Tafaleng, Edgar N., Mukherjee, Amitava, Troy, Kris, Banerjee, Swati, Paranjpe, Shirish, Michalopoulos, George K., Bell, Aaron, Nagrath, Deepak, Hainer, Sarah J., Fox, Ira J., Soto‐Gutierrez, Alejandro

Volltext

Assembly of Human Organs from Stem Cells to Study Liver Disease von Handa, Kan, Matsubara, Kentaro, Fukumitsu, Ken, Guzman-Lepe, Jorge, Watson, Alicia, Soto-Gutierrez, Alejandro

Volltext

1066 Localized airway delivery of Interleukins-12 and -2 via inhalation of a replication-defective HSV-1-based therapy for the treatment of primary and secondary lung tumors von Previte, Dana, Duermeyer, Mary Jane, Lepe, Jorge Guzman, Parry, Trevor, Krishnan, Suma

Volltext

1065 A replication-defective, HSV-1-based gene therapy for localized delivery of combinatorial Interleukins-12 and -2 for the treatment of cutaneous malignancies von Previte, Dana, Duermeyer, Mary Jane, Lepe, Jorge Guzman, Parry, Trevor, Krishnan, Suma

Volltext

Current strategies to generate mature human induced pluripotent stem cells derived cholangiocytes and future applications von Cervantes-Alvarez, Eduardo, Wang, Yang, Collin de l'Hortet, Alexandra, Guzman-Lepe, Jorge, Zhu, Jiye, Takeishi, Kazuki

Volltext

A Nonhuman Primate Model of Human Radiation-Induced Venocclusive Liver Disease and Hepatocyte Injury von Yannam, Govardhana Rao, MD, Han, Bing, MD, Setoyama, Kentaro, DVM, PhD, Yamamoto, Toshiyuki, MD, Ito, Ryotaro, MD, Brooks, Jenna M., BS, Guzman-Lepe, Jorge, MD, Galambos, Csaba, MD, PhD, Fong, Jason V., MD, Deutsch, Melvin, MD, Quader, Mubina A., PhD, Yamanouchi, Kosho, MD, PhD, Kabarriti, Rafi, MD, Mehta, Keyur, MD, Soto-Gutierrez, Alejandro, MD, PhD, Roy-Chowdhury, Jayanta, MD, Locker, Joseph, MD, PhD, Abe, Michio, MD, Enke, Charles A., MD, Baranowska-Kortylewicz, Janina, PhD, Solberg, Timothy D., PhD, Guha, Chandan, MBBS, PhD, Fox, Ira J., MD

Volltext

Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism von Collin de l’Hortet, Alexandra, Takeishi, Kazuki, Guzman-Lepe, Jorge, Morita, Kazutoyo, Achreja, Abhinav, Popovic, Branimir, Wang, Yang, Handa, Kan, Mittal, Anjali, Meurs, Noah, Zhu, Ziwen, Weinberg, Frank, Salomon, Michael, Fox, Ira J., Deng, Chu-Xia, Nagrath, Deepak, Soto-Gutierrez, Alejandro

Volltext

Increased Reprogramming of Human Fetal Hepatocytes Compared with Adult Hepatocytes in Feeder-Free Conditions von Hansel, Marc C., Gramignoli, Roberto, Blake, William, Davila, Julio, Skvorak, Kristen, Dorko, Kenneth, Tahan, Veysel, Lee, Brian R., Tafaleng, Edgar, Guzman-Lepe, Jorge, Soto-Gutierrez, Alejandro, Fox, Ira J., Strom, Stephen C.

Volltext

Regulation of Cytosolic Sulfotransferases in Models of Human Hepatocyte Development von Dubaisi, Sarah, Barrett, Kathleen G., Fang, Hailin, Guzman-Lepe, Jorge, Soto-Gutierrez, Alejandro, Kocarek, Thomas A., Runge-Morris, Melissa

Volltext

Microenvironment of a tumor-organoid system enhances hepatocellular carcinoma malignancy-related hallmarks von Wang, Yang, Takeishi, Kazuki, Li, Zhao, Cervantes-Alvarez, Eduardo, Collin de l'Hortet, Alexandra, Guzman-Lepe, Jorge, Cui, Xiao, Zhu, Jiye

Volltext

Regeneration and Cell Recruitment in an Improved Heterotopic Auxiliary Partial Liver Transplantation Model in the Rat von Ono, Yoshihiro, Pérez-Gutiérrez, Angelica, Yovchev, Mladen I, Matsubara, Kentaro, Yokota, Shinichiro, Guzman-Lepe, Jorge, Handa, Kan, Collin de l’Hortet, Alexandra, Thomson, Angus W, Geller, David A, Yagi, Hiroshi, Oertel, Michael, Soto-Gutierrez, Alejandro

Volltext

From hacking the human genome to editing organs von Tobita, Takamasa, Guzman-Lepe, Jorge, Collin de l'Hortet, Alexandra

Volltext

Lethal Outcomes in Klippel-Trenaunay Syndrome von Karunamurthy, Arivarasan, Pantanowitz, Liron, Lepe, Jorge Guzman, Reyes-Múgica, Miguel

Volltext

A non-human primate model of human radiation-induced venocclusive liver disease and hepatocyte injury von Yannam, Govardhana Rao, Han, Bing, Setoyama, Kentaro, Yamamoto, Toshiyuki, Ito, Ryotaro, Brooks, Jenna M., Guzman-Lepe, Jorge, Galambos, Csaba, Fong, Jason V., Deutsch, Melvin, Quader, Mubina A., Yamanouchi, Kosho, Kabarriti, Rafi, Mehta, Keyur, Soto-Gutierrez, Alejandro, Roy-Chowdhury, Jayanta, Locker, Joseph, Abe, Michio, Enke, Charles A., Baranowska-Kortylewicz, Janina, Solberg, Timothy D., Guha, Chandan, Fox, Ira J.

Volltext

Human induced pluripotent stem cells for high efficiency genetic engineering von Takeishi, Kazuki, Soto-Gutierrez, Alejandro, Collin de l'Hortet, Alexandra Sylvie, Lepe, Jorge Guzman, Fox, Ira Jacob, Handa, Kan, Wang, Yang

Volltext bestellen

COMPOSITIONS AND METHODS FOR TREATING LIVER DISEASE von TAKEISHI, Kazuki, SOTO GUTIERREZ, Alejandro, OSTROWSKA, Alina, GUZMAN LEPE, Jorge, FOX, Ira, FRAUNHOFFER NAVARRO, Nicolas, TAFALENG, Edgar Naoe, MICHALOPOULOS, George K, BELL, Aaron, HAINER, Sarah

Volltext bestellen