A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors von Conroy, Jeffrey M, Pabla, Sarabjot, Glenn, Sean T, Seager, R J, Van Roey, Erik, Gao, Shuang, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Mallon, Melissa, Lee, Yong Hee, DePietro, Paul, Nesline, Mary, Wang, Yirong, Lenzo, Felicia L, Klein, Roger, Zhang, Shengle

Volltext

Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity von Kato, Shumei, Okamura, Ryosuke, Kumaki, Yuichi, Ikeda, Sadakatsu, Nikanjam, Mina, Eskander, Ramez, Goodman, Aaron, Lee, Suzanna, Glenn, Sean T., Dressman, Devin, Papanicolau-Sengos, Antonios, Lenzo, Felicia L., Morrison, Carl, Kurzrock, Razelle

Volltext

Analytical Validation of a Next-Generation Sequencing Assay to Monitor Immune Responses in Solid Tumors von Conroy, Jeffrey M., Pabla, Sarabjot, Glenn, Sean T., Burgher, Blake, Nesline, Mary, Papanicolau-Sengos, Antonios, Andreas, Jonathan, Giamo, Vincent, Lenzo, Felicia L., Hyland, Fiona C.L., Omilian, Angela, Bshara, Wiam, Qin, Moachun, He, Ji, Puzanov, Igor, Ernstoff, Marc S., Gardner, Mark, Galluzzi, Lorenzo, Morrison, Carl

Volltext

Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors von Marlowe, Timothy A, Lenzo, Felicia L, Figel, Sheila A, Grapes, Abigail T, Cance, William G

Volltext

Development and analytical validation of a next-generation sequencing based microsatellite instability (MSI) assay von Pabla, Sarabjot, Andreas, Jonathan, Lenzo, Felicia L, Burgher, Blake, Hagen, Jacob, Giamo, Vincent, Nesline, Mary K, Wang, Yirong, Gardner, Mark, Conroy, Jeffrey M, Papanicolau-Sengos, Antonios, Morrison, Carl, Glenn, Sean T

Volltext

PD-L2 amplification and durable disease stabilization in patient with urothelial carcinoma receiving pembrolizumab von George, Saby, Papanicolau-Sengos, Antonios, Lenzo, Felicia L, Conroy, Jeffrey M, Nesline, Mary, Pabla, Sarabjot, Glenn, Sean T, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Qin, Moachun, Wang, Yirong, Galluzzi, Lorenzo, Morrison, Carl

Volltext

Integration of tumor inflammation, cell proliferation, and traditional biomarkers improves prediction of immunotherapy resistance and response von Pabla, Sarabjot, Seager, R J, Van Roey, Erik, Gao, Shuang, Hoefer, Carrie, Nesline, Mary K, DePietro, Paul, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Wang, Yirong, Lenzo, Felicia L, Schoenborn, Margot, Zhang, Shengle, Klein, Roger, Glenn, Sean T, Conroy, Jeffrey M

Volltext

Proliferative potential and response to nivolumab in clear cell renal cell carcinoma patients von Zhang, Tian, Pabla, Sarabjot, Lenzo, Felicia L., Conroy, Jeffrey M., Nesline, Mary K., Glenn, Sean T., Papanicolau-Sengos, Antonios, Burgher, Blake, Giamo, Vincent, Andreas, Jonathan, Wang, Yirong, Bshara, Wiam, Madden, Katherine G., Shirai, Keisuke, Dragnev, Konstantin, Tafe, Laura J., Gupta, Rajan, Zhu, Jason, Labriola, Matthew, McCall, Shannon, George, Daniel J., Ghatalia, Pooja, Dayyani, Farshid, Edwards, Robert, Park, Michelle S, Singh, Rajbir, Jacob, Robin, George, Saby, Xu, Bo, Zibelman, Matthew, Kurzrock, Razelle, Morrison, Carl

Volltext

Identification of targets for prostate cancer immunotherapy von Papanicolau‐Sengos, Antonios, Yang, Yuanquan, Pabla, Sarabjot, Lenzo, Felicia L., Kato, Shumei, Kurzrock, Razelle, DePietro, Paul, Nesline, Mary, Conroy, Jeffrey, Glenn, Sean, Chatta, Gurkamal, Morrison, Carl

Volltext

Predicting response to checkpoint inhibitors in melanoma beyond PD-L1 and mutational burden von Morrison, Carl, Pabla, Sarabjot, Conroy, Jeffrey M, Nesline, Mary K, Glenn, Sean T, Dressman, Devin, Papanicolau-Sengos, Antonios, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Qin, Moachun, Wang, Yirong, Lenzo, Felicia L, Omilian, Angela, Bshara, Wiam, Zibelman, Matthew, Ghatalia, Pooja, Dragnev, Konstantin, Shirai, Keisuke, Madden, Katherine G, Tafe, Laura J, Shah, Neel, Kasuganti, Deepa, de la Cruz-Merino, Luis, Araujo, Isabel, Saenger, Yvonne, Bogardus, Margaret, Villalona-Calero, Miguel, Diaz, Zuanel, Day, Roger, Eisenberg, Marcia, Anderson, Steven M, Puzanov, Igor, Galluzzi, Lorenzo, Gardner, Mark, Ernstoff, Marc S

Volltext

Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients von Pabla, Sarabjot, Conroy, Jeffrey M, Nesline, Mary K, Glenn, Sean T, Papanicolau-Sengos, Antonios, Burgher, Blake, Hagen, Jacob, Giamo, Vincent, Andreas, Jonathan, Lenzo, Felicia L, Yirong, Wang, Dy, Grace K, Yau, Edwin, Early, Amy, Chen, Hongbin, Bshara, Wiam, Madden, Katherine G, Shirai, Keisuke, Dragnev, Konstantin, Tafe, Laura J, Marin, Daniele, Zhu, Jason, Clarke, Jeff, Labriola, Matthew, McCall, Shannon, Zhang, Tian, Zibelman, Matthew, Ghatalia, Pooja, Araujo-Fernandez, Isabel, Singavi, Arun, George, Ben, MacKinnon, Andrew Craig, Thompson, Jonathan, Singh, Rajbir, Jacob, Robin, Dressler, Lynn, Steciuk, Mark, Binns, Oliver, Kasuganti, Deepa, Shah, Neel, Ernstoff, Marc, Odunsi, Kunle, Kurzrock, Razelle, Gardner, Mark, Galluzzi, Lorenzo, Morrison, Carl

Volltext

Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors von Conroy, Jeffrey M, Pabla, Sarabjot, Nesline, Mary K, Glenn, Sean T, Papanicolau-Sengos, Antonios, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Wang, Yirong, Lenzo, Felicia L, Bshara, Wiam, Khalil, Maya, Dy, Grace K, Madden, Katherine G, Shirai, Keisuke, Dragnev, Konstantin, Tafe, Laura J, Zhu, Jason, Labriola, Matthew, Marin, Daniele, McCall, Shannon J, Clarke, Jeffrey, George, Daniel J, Zhang, Tian, Zibelman, Matthew, Ghatalia, Pooja, Araujo-Fernandez, Isabel, de la Cruz-Merino, Luis, Singavi, Arun, George, Ben, MacKinnon, Alexander C, Thompson, Jonathan, Singh, Rajbir, Jacob, Robin, Kasuganti, Deepa, Shah, Neel, Day, Roger, Galluzzi, Lorenzo, Gardner, Mark, Morrison, Carl

Volltext

Immune profiling and immunotherapeutic targets in pancreatic cancer von Lenzo, Felicia L, Kato, Shumei, Pabla, Sarabjot, DePietro, Paul, Nesline, Mary K, Conroy, Jeffrey M, Burgher, Blake, Glenn, Sean T, Kuvshinoff, Boris, Kurzrock, Razelle, Morrison, Carl

Volltext

Oncologist uptake of comprehensive genomic profile guided targeted therapy von Nesline, Mary K, DePietro, Paul, Dy, Grace K, Early, Amy, Papanicolau-Sengos, Antonios, Conroy, Jeffrey M, Lenzo, Felicia L, Glenn, Sean T, Chen, Hongbin, Grand'Maison, Anne, Boland, Patrick, Ernstoff, Marc S, Puzanov, Igor, Edge, Stephen, Akers, Stacey, Opyrchal, Mateusz, Chatta, Gurkamal, Odunsi, Kunle, Frederick, Peter, Lele, Shashikant, Gardner, Mark, Morrison, Carl

Volltext

From tumorigenesis to microenvironment and immunoregulation: the many faces of focal adhesion kinase and challenges associated with targeting this elusive protein von Lenzo, Felicia L., Cance, William G.

Volltext

Treatment recommendations to cancer patients in the context of FDA guidance for next generation sequencing von Dy, Grace K, Nesline, Mary K, Papanicolau-Sengos, Antonios, DePietro, Paul, LeVea, Charles M, Early, Amy, Chen, Hongbin, Grand'Maison, Anne, Boland, Patrick, Ernstoff, Marc S, Edge, Stephen, Akers, Stacey, Opyrchal, Mateusz, Chatta, Gurkamal, Odunsi, Kunle, Pabla, Sarabjot, Conroy, Jeffrey M, Glenn, Sean T, DeFedericis, Hanchun T, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Qin, Maochun, Wang, Yirong, Kanehira, Kazunori, Lenzo, Felicia L, Frederick, Peter, Lele, Shashikant, Galluzzi, Lorenzo, Kuvshinoff, Boris, Morrison, Carl

Volltext

Tamoxifen increases nuclear respiratory factor 1 transcription by activating estrogen receptor β and AP‐1 recruitment to adjacent promoter binding sites von Ivanova, Margarita M., Luken, Kristen H., Zimmer, Amber S., Lenzo, Felicia L., Smith, Ryan J., Arteel, Maia W., Kollenberg, Tara J., Mattingly, Kathleen A., Klinge, Carolyn M.

Volltext

Tumor inflammatory signature as a biomarker of response to immunotherapy in lung cancer von Pabla, Sarabjot, Van Roey, Erik, Conroy, Jeffrey M., Glenn, Sean, Wang, Yirong, Nesline, Mary, Burgher, Blake, Giamo, Vincent, Andreas, Jonathan, Lenzo, Felicia L., Morrison, Carl

Volltext

Tumor mutational burden (TMB): Assessment of inter- and intra-tumor heterogeneity von Conroy, Jeffrey M., Pabla, Sarabjot, Glenn, Sean T., Nesline, Mary, Burgher, Blake, Lenzo, Felicia L., Papanicolau-Sengos, Antonios, Gardner, Mark, Morrison, Carl

Volltext

Inflammation and cell proliferation signatures: Implications for response to immune checkpoint inhibition therapies von Glenn, Sean, Pabla, Sarabjot, Kato, Shumei, Van Roey, Erik, Conroy, Jeffrey M., Wang, Yirong, Nesline, Mary, Burgher, Blake, Giamo, Vincent, Andreas, Jonathan, Lenzo, Felicia L., Kurzrock, Razelle, Morrison, Carl

Volltext