Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: A mini review von Lenz, David E, Yeung, David, Smith, J. Richard, Sweeney, Richard E, Lumley, Lucille A, Cerasoli, Douglas M

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Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning von Huang, Yue-Jin, Huang, Yue, Baldassarre, Hernan, Wang, Bin, Lazaris, Anthoula, Leduc, Martin, Bilodeau, Annie S, Bellemare, Annie, Côté, Mélanie, Herskovits, Peter, Touati, Madjid, Turcotte, Carl, Valeanu, Loredana, Lemée, Nicolas, Wilgus, Harvey, Bégin, Isabelle, Bhatia, Bhim, Rao, Khalid, Neveu, Nathalie, Brochu, Eric, Pierson, Janice, Hockley, Duncan K, Cerasoli, Douglas M, Lenz, David E, Karatzas, Costas N, Langermann, Solomon

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Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents von Geyer, Brian C., Kannan, Latha, Garnaud, Pierre-Emmanuel, Broomfield, Clarence A., Cadieux, C. Linn, Cherni, Irene, Hodgins, Sean M., Kasten, Shane A., Kelley, Karli, Kilbourne, Jacquelyn, Oliver, Zeke P., Otto, Tamara C., Puffenberger, Ian, Reeves, Tony E., Robbins, Neil, Woods, Ryan R., Soreq, Hermona, Lenz, David E., Cerasoli, Douglas M., Mor, Tsafrir S., Arntzen, Charles J.

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Substantially improved pharmacokinetics of recombinant human butyrylcholinesterase by fusion to human serum albumin von Huang, Yue-Jin, Lundy, Paul M, Lazaris, Anthoula, Huang, Yue, Baldassarre, Hernan, Wang, Bin, Turcotte, Carl, Côté, Mélanie, Bellemare, Annie, Bilodeau, Annie S, Brouillard, Sandra, Touati, Madjid, Herskovits, Peter, Bégin, Isabelle, Neveu, Nathalie, Brochu, Eric, Pierson, Janice, Hockley, Duncan K, Cerasoli, Douglas M, Lenz, David E, Wilgus, Harvey, Karatzas, Costas N, Langermann, Solomon

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Bioscavenger for protection from toxicity of organophosphorus compounds von Saxena, Ashima, Sun, Wei, Luo, Chunyuan, Myers, Todd M, Koplovitz, Irwin, Lenz, David E, Doctor, Bhupendra P

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Radiolabelled soman binding to sera from Rats, Guinea Pigs and Monkeys von Lenz, David E., Cerasoli, Douglas, Maxwell, Donald M.

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Analysis of active‐site amino‐acid residues of human serum paraoxonase using competitive substrates von Yeung, David T., Lenz, David E., Cerasoli, Douglas M.

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Butyrylcholinesterase, a stereospecific in vivo bioscavenger against nerve agent intoxication von Cerasoli, Douglas M., Armstrong, Stuart J., Reeves, Tony E., Hodgins, Sean M., Kasten, Shane A., Lee-Stubbs, Robyn B., Cadieux, C. Linn, Otto, Tamara C., Capacio, Benedict R., Lenz, David E.

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Human butyrylcholinesterase efficacy against nerve agent exposure von Reed, Beth A., Sabourin, Carol L., Lenz, David E.

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Comparison of human and guinea pig acetylcholinesterase sequences and rates of oxime-assisted reactivation von Cadieux, C. Linn, Broomfield, Clarence A., Kirkpatrick, Melanie G., Kazanski, Meghan E., Lenz, David E., Cerasoli, Douglas M.

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In silico analyses of substrate interactions with human serum paraoxonase 1 von Hu, Xin, Jiang, Xiaohui, Lenz, David E., Cerasoli, Douglas M., Wallqvist, Anders

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A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters von Masson, Patrick, Nachon, Florian, Broomfield, Clarence A., Lenz, David E., Verdier, Laurent, Schopfer, Lawrence M., Lockridge, Oksana

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Dramatic Differences in Organophosphorus Hydrolase Activity between Human and Chimeric Recombinant Mammalian Paraoxonase-1 Enzymes von Otto, Tamara C, Harsch, Christina K, Yeung, David T, Magliery, Thomas J, Cerasoli, Douglas M, Lenz, David E

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Butyrylcholinesterase as a therapeutic drug for protection against percutaneous VX von Lenz, David E., Clarkson, Edward D., Schulz, Susan M., Cerasoli, Douglas M.

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Effect of octanol:water partition coefficients of organophosphorus compounds on biodistribution and percutaneous toxicity von Czerwinski, Steven E., Skvorak, John P., Maxwell, Donald M., Lenz, David E., Baskin, Steven I.

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Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys von Lenz, David E., Maxwell, Donald M., Koplovitz, Irwin, Clark, Connie R., Capacio, Benjamin R., Cerasoli, Douglas M., Federko, James M., Luo, Chunyuan, Saxena, Ashima, Doctor, Bhupendra P., Olson, Carl

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Solubilization and Humanization of Paraoxonase-1 von Sarkar, Mohosin, Harsch, Christina Keventzidis, Matic, George T., Hoffman, Kathryn, Norris, Joseph R., Otto, Tamara C., Lenz, David E., Cerasoli, Douglas M., Magliery, Thomas J.

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Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae von Otto, Tamara C., Kasten, Shane A., Kovaleva, Elena, Liu, Zhi, Buchman, George, Tolosa, Marita, Davis, David, Smith, J. Richard, Balcerzak, Robert, Lenz, David E., Cerasoli, Douglas M.

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Direct detection of stereospecific soman hydrolysis by wild‐type human serum paraoxonase von Yeung, David T., Smith, J. Richard, Sweeney, Richard E., Lenz, David E., Cerasoli, Douglas M.

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Efficacy and physiological effects of human butyrylcholinesterase as a post-exposure therapy against percutaneous poisoning by VX in the guinea-pig von Mumford, Helen, Price, Matthew E., Cerasoli, Douglas M., Teschner, Wolfgang, Ehrlich, Hartmut, Schwarz, Hans Peter, Lenz, David E.

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