Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198 von Molenaar, Remco J, Botman, Dennis, Smits, Myrthe A, Hira, Vashendriya V, van Lith, Sanne A, Stap, Jan, Henneman, Peter, Khurshed, Mohammed, Lenting, Krissie, Mul, Adri N, Dimitrakopoulou, Dionysia, van Drunen, Cornelis M, Hoebe, Ron A, Radivoyevitch, Tomas, Wilmink, Johanna W, Maciejewski, Jaroslaw P, Vandertop, W Peter, Leenders, William P, Bleeker, Fonnet E, van Noorden, Cornelis J

Volltext

In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma von Khurshed, Mohammed, Molenaar, Remco J, Lenting, Krissie, Leenders, William P, van Noorden, Cornelis J F

Volltext

Isocitrate dehydrogenase 1–mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress von Lenting, Krissie, Khurshed, Mohammed, Peeters, Tom H., Heuvel, Corina N. A. M., Lith, Sanne A. M., Bitter, Tessa, Hendriks, Wiljan, Span, Paul N., Molenaar, Remco J., Botman, Dennis, Verrijp, Kiek, Heerschap, Arend, Laan, Mark, Kusters, Benno, Ewijk, Anne, Huynen, Martijn A., Noorden, Cornelis J. F., Leenders, William P. J.

Volltext

Glioma: experimental models and reality von Lenting, Krissie, Verhaak, Roel, ter Laan, Mark, Wesseling, Pieter, Leenders, William

Volltext

Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma von van Lith, Sanne A. M., Navis, Anna C., Lenting, Krissie, Verrijp, Kiek, Schepens, Jan T. G., Hendriks, Wiljan J. A. J., Schubert, Nil A., Venselaar, Hanka, Wevers, Ron A., van Rooij, Arno, Wesseling, Pieter, Molenaar, Remco J., van Noorden, Cornelis J. F., Pusch, Stefan, Tops, Bastiaan, Leenders, William P. J.

Volltext

Mapping actionable pathways and mutations in brain tumours using targeted RNA next generation sequencing von Lenting, Krissie, van den Heuvel, Corina N A M, van Ewijk, Anne, ElMelik, Duaa, de Boer, Remco, Tindall, Elizabeth, Wei, Ge, Kusters, Benno, Te Dorsthorst, Maarten, Ter Laan, Mark, Huynen, Martijn A, Leenders, William P

Volltext

Isocitrate dehydrogenase 1 -mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallate von Peeters, Tom H, Lenting, Krissie, Breukels, Vincent, van Lith, Sanne A M, van den Heuvel, Corina N A M, Molenaar, Remco, van Rooij, Arno, Wevers, Ron, Span, Paul N, Heerschap, Arend, Leenders, William P J

Volltext

IDH1‐mutated gliomas rely on anaplerosis of glutamate and lactate whereas IDH1 wild‐type gliomas rely on glycolysis and acetate anaplerosis von Khurshed, Mohammed, Lenting, Krissie, Peeters, Tom, Molenaar, Remco J., Leenders, William, Noorden, Cornelis

Volltext

Abstract 431: IDH1-mutated gliomas rely on anaplerosis of glutamate and lactate whereas IDH1 wild-type gliomas rely on glycolysis and acetate anaplerosis von Khurshed, Mohammed, Lenting, Krissie, Molenaar, Remco J., Leenders, William P., Noorden, Cornelis J. van

Volltext

Glioma: experimental models and reality von Lenting, Krissie, Verhaak, Roel, ter Laan, Mark, Wesseling, Pieter, Leenders, William

Volltext

Imaging Hyperpolarized Pyruvate and Lactate after Blood–Brain Barrier Disruption with Focused Ultrasound von Peeters, Tom H, Kobus, Thiele, Breukels, Vincent, Lenting, Krissie, Veltien, Andor, Heerschap, Arend, Scheenen, Tom W. J

Volltext

Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma von Van Lith, Sanne A M, Navis, Anna C, Lenting, Krissie, Verrijp, Kiek, Schepens, Jan T G, Hendriks, Wiljan J A J, Schubert, Nil A, Venselaar, Hanka, Wevers, Ron A, Van Rooij, Arno, Wesseling, Pieter, Molenaar, Remco J, Van Noorden, Cornelis J F, Pusch, Stefan, Tops, Bastiaan, Leenders, William P J

Volltext

Additional file 1: of Isocitrate dehydrogenase 1-mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallate von Peeters, Tom, Krissie Lenting, Breukels, Vincent, Lith, Sanne, Heuvel, Corina, Molenaar, Remco, Rooij, Arno, Wevers, Ron, Span, Paul, Heerschap, Arend, Leenders, William

Volltext bestellen