TEM8/ANTXR1 Blockade Inhibits Pathological Angiogenesis and Potentiates Tumoricidal Responses against Multiple Cancer Types von Chaudhary, Amit, Hilton, Mary Beth, Seaman, Steven, Haines, Diana C., Stevenson, Susan, Lemotte, Peter K., Tschantz, William R., Zhang, Xiaoyan M., Saha, Saurabh, Fleming, Tony, St. Croix, Brad

Volltext

Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung von Danahay, Henry, Pessotti, Angelica D., Coote, Julie, Montgomery, Brooke E., Xia, Donghui, Wilson, Aaron, Yang, Haidi, Wang, Zhao, Bevan, Luke, Thomas, Chris, Petit, Stephanie, London, Anne, LeMotte, Peter, Doelemeyer, Arno, Vélez-Reyes, Germán L., Bernasconi, Paula, Fryer, Christy J., Edwards, Matt, Capodieci, Paola, Chen, Amy, Hild, Marc, Jaffe, Aron B.

Volltext

Kinetic Analysis of Estrogen Receptor/Ligand Interactions von Rich, Rebecca L., Hoth, Lise R., Geoghegan, Kieran F., Brown, Thomas A., LeMotte, Peter K., Simons, Samuel P., Hensley, Preston, Myszka, David G.

Volltext

Structural basis for the catalytic mechanism of human phosphodiesterase 9 von Liu, Shenping, Mansour, Mahmoud N, Dillman, Keith S, Perez, Jose R, Danley, Dennis E, Aeed, Paul A, Simons, Samuel P, LeMotte, Peter K, Menniti, Frank S

Volltext

Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies von Bernasconi-Elias, P, Hu, T, Jenkins, D, Firestone, B, Gans, S, Kurth, E, Capodieci, P, Deplazes-Lauber, J, Petropoulos, K, Thiel, P, Ponsel, D, Hee Choi, S, LeMotte, P, London, A, Goetcshkes, M, Nolin, E, Jones, M D, Slocum, K, Kluk, M J, Weinstock, D M, Christodoulou, A, Weinberg, O, Jaehrling, J, Ettenberg, S A, Buckler, A, Blacklow, S C, Aster, J C, Fryer, C J

Volltext

Purification of the large ribosomal subunit via its association with the small subunit von Simons, Samuel P., McLellan, Thomas J., Aeed, Paul A., Zaniewski, Richard P., Desbonnet, Charlene R., Wondrack, Lillian M., Marr, Eric S., Subashi, Timothy A., Dougherty, Thomas J., Xu, Zuoyu, Wang, Ing-Kae, LeMotte, Peter K., Maguire, Bruce A.

Volltext

Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TRβ subtype-selective thyromimetics von Dow, Robert L., Schneider, Steven R., Paight, Ernest S., Hank, Richard F., Chiang, Phoebe, Cornelius, Peter, Lee, Eunsun, Newsome, William P., Swick, Andrew G., Spitzer, Josephine, Hargrove, Diane M., Patterson, Terrell A., Pandit, Jayvardhan, Chrunyk, Boris A., LeMotte, Peter K., Danley, Dennis E., Rosner, Michele H., Ammirati, Mark J., Simons, Samuel P., Schulte, Gayle K., Tate, Bonnie F., DaSilva-Jardine, Paul

Volltext

Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin von Xie, Yang, Zamponi, Raffaella, Charlat, Olga, Ramones, Melissa, Swalley, Susanne, Jiang, Xiaomo, Rivera, Daniel, Tschantz, William, Lu, Bo, Quinn, Lisa, Dimitri, Chris, Parker, Jefferson, Jeffery, Doug, Wilcox, Sheri K, Watrobka, Mike, LeMotte, Peter, Granda, Brian, Porter, Jeffrey A, Myer, Vic E, Loew, Andreas, Cong, Feng

Volltext

Phosphorylation of serine residues in histidine-tag sequences attached to recombinant protein kinases: A cause of heterogeneity in mass and complications in function von Du, Ping, Loulakis, Pat, Luo, Chun, Mistry, Anil, Simons, Samuel P., LeMotte, Peter K., Rajamohan, Francis, Rafidi, Kristina, Coleman, Kevin G., Geoghegan, Kieran F., Xie, Zhi

Volltext

Enhancement of HL-60 Differentiation by a New Class of Retinoids with Selective Activity on Retinoid X Receptor (∗) von Apfel, Christian M., Kamber, Markus, Klaus, Michael, Mohr, Peter, Keidel, Siegfried, LeMotte, Peter K.

Volltext

Differential expression of CRABP II, psoriasin and cytokeratin 1 mRNA in human skin diseases von ALGERMISSEN, B, SITZMANN, J, LEMOTTE, P, CZARNETZKI, B

Volltext

Characterization of activating mutations of NOTCH3 in T cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies von Bernasconi-Elias, Paula, Hu, Tiancen, Jenkins, David, Firestone, Brant, Gans, Sara, Kurth, Esther, Capodieci, Paola, Deplazes-Lauber, Joelle, Petropoulos, Konstantin, Thiel, Phillip, Ponsel, Dirk, Choi, Sung Hee, LeMotte, Peter, London, Anne, Goetcshkes, Margaret, Nolin, Erin, Jones, Michael D, Slocum, Kelly, Kluk, Michael J, Weinstock, David M, Christodoulou, Alexandra, Weinberg, Olga, Jaehrling, Jan, Ettenberg, Seth A, Buckler, Alan, Blacklow, Stephen C, Aster, Jon C, Fryer, Christy J

Volltext

The 2.0 Å crystal structure of the ERα ligand‐binding domain complexed with lasofoxifene von Vajdos, Felix F., Hoth, Lise R., Geoghegan, Kieran F., Simons, Samuel P., LeMotte, Peter K., Danley, Dennis E., Ammirati, Mark J., Pandit, Jayvardhan

Volltext

Characterization of synthetic retinoids with selectivity for retinoic acid or retinoid X nuclear receptors von LeMotte, Peter K, Keidel, Siegfried, Apfel, Christian M

Volltext

Theoretical and Experimental Design of Atypical Kinase Inhibitors:  Application to p38 MAP Kinase von McClure, Kim F, Abramov, Yuriy A, Laird, Ellen R, Barberia, John T, Cai, Weiling, Carty, Thomas J, Cortina, Santo R, Danley, Dennis E, Dipesa, Alan J, Donahue, Kathleen M, Dombroski, Mark A, Elliott, Nancy C, Gabel, Christopher A, Han, Seungil, Hynes, Thomas R, LeMotte, Peter K, Mansour, Mahmoud N, Marr, Eric S, Letavic, Michael A, Pandit, Jayvardhan, Ripin, David B, Sweeney, Francis J, Tan, Douglas, Tao, Yong

Volltext

Phytanic Acid is a Retinoid X Receptor Ligand von Lemotte, Peter K., Keidel, Siegfried, Apfel, Christian M.

Volltext

Spontaneous alpha-N-6-phosphogluconoylation of a "His tag" in Escherichia coli: the cause of extra mass of 258 or 178 Da in fusion proteins von Geoghegan, K F, Dixon, H B, Rosner, P J, Hoth, L R, Lanzetti, A J, Borzilleri, K A, Marr, E S, Pezzullo, L H, Martin, L B, LeMotte, P K, McColl, A S, Kamath, A V, Stroh, J G

Volltext

Activation of Human Liver Glycogen Phosphorylase by Alteration of the Secondary Structure and Packing of the Catalytic Core von Rath, Virginia L., Ammirati, Mark, LeMotte, Peter K., Fennell, Kimberly F., Mansour, Mahmoud N., Danley, Dennis E., Hynes, Thomas R., Schulte, Gayle K., Wasilko, David J., Pandit, Jayvardhan

Volltext

Different agonist- and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mapping von KEIDEL, S, LEMOTTE, P, APFEL, C

Volltext

The 2.0 A crystal structure of the ERalpha ligand-binding domain complexed with lasofoxifene von Vajdos, Felix F, Hoth, Lise R, Geoghegan, Kieran F, Simons, Samuel P, LeMotte, Peter K, Danley, Dennis E, Ammirati, Mark J, Pandit, Jayvardhan

Volltext