Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody–Drug Conjugate SYD985 von Elgersma, Ronald C, Coumans, Ruud G. E, Huijbregts, Tijl, Menge, Wiro M. P. B, Joosten, John A. F, Spijker, Henri J, de Groot, Franciscus M. H, van der Lee, Miranda M. C, Ubink, Ruud, van den Dobbelsteen, Diels J, Egging, David F, Dokter, Wim H. A, Verheijden, Gijs F. M, Lemmens, Jacques M, Timmers, C. Marco, Beusker, Patrick H

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Abstract 5360: The preclinical profile of the duocarmycin-based HER2-targeting ADC SYD985 predicts for clinical benefit in low HER2-expressing breast cancers von Dokter, Willem, van der Lee, Miranda, Groothuis, Patrick, Ubink, Ruud, van der Vleuten, Monique, van Achterberg, Tanja, Loosveld, Eline, Damming, Desirée, Rouwette, Myrthe, Egging, David, van den Dobbelsteen, Diels, Beusker, Patrick, goedings, peter, Verheijden, Gijs, Lemmens, Jacques, Timmers, Marco

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Abstract 4329: Novel HER2 targeting antibody-drug conjugates based on DNA-interacting duocarmycin and an unique linker technology with great potential in breast cancer and NSCLC von Dokter, Wim, Beusker, Patrick, Verheijden, Gijs, Ubink, Ruud, van der Lee, Miranda, van den Dobbelsteen, Diels, Goedings, Peter, Lemmens, Jacques, de Groot, Vincent, Timmers, Marco

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Synthesis of .alpha.,.beta.-epoxyacyl azides and their rearrangement to epoxy isocyanates and 3- and 4-oxazolin-2-ones von Lemmens, Jacques M, Blommerde, Willem W. J. M, Thijs, Lambertus, Zwanenburg, Binne

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Global, regional and national burden of primary liver cancer by subtype von Rumgay, Harriet, Ferlay, Jacques, de Martel, Catherine, Georges, Damien, Ibrahim, Amal Samy, Zheng, Rongshou, Wei, Wenqiang, Lemmens, Valery E.P.P., Soerjomataram, Isabelle

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Device for insertion of implant comprising polymer rod applied subcutaneously, abdominally or intra muscularly, allowing active material over period to be infused into body von JACQUES MARIA LEMMENS, DENNIE JOHAN MARIJN VAN DEN HEUVEL, FRANS VAN DALEN

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Modified release formulations containing a hypnotic agent von JACQUES MARIA LEMMENS, JOHANNES JAN PLATTEEUW, DENNIE JOHAN MARIJN VAN DEN HEUVEL, FRANS VAN DALEN

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Determining and benchmarking risk neutral distributions implied from option prices von Salazar Celis, Oliver, Liang, Lingzhi, Lemmens, Damiaan, Tempère, Jacques, Cuyt, Annie

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ART in Europe, 2015: results generated from European registries by ESHRE von De Geyter, C, Calhaz-Jorge, C, Kupka, M S, Wyns, C, Mocanu, E, Motrenko, T, Scaravelli, G, Smeenk, J, Vidakovic, S, Goossens, V

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Policies and practices impacting the implementation of nature-based solutions: a comparative study of ponds and pondscapes in eight countries von Ryfisch, Simon, Başoğlu Acet, Deniz, Benejam, Lluís, Biggs, Jeremy, Boissezon, Aurélie, Boix, Dani, Brucet, Sandra, Decrey, Marine, Dolcerocca, Antoine, Hansen, Kristoffer, Lago, Manuel, Lemmens, Pieter, Lindoso, Diego, Llausàs, Albert, McDonald, Hugh, Meerhoff, Mariana, Mehner, Thomas, Pereira, Gissel, Perrin, Jacques-Aristide, Quintana, Xavier D., Rasmussen, Marzenna, Ribas, Anna, Sander Johansson, Liselotte, Wijns, Robby, Blicharska, Malgorzata

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ART in Europe, 2017: results generated from European registries by ESHRE von Wyns, C, De Geyter, Ch, Calhaz-Jorge, C, Kupka, M S, Motrenko, T, Smeenk, J, Bergh, C, Tandler-Schneider, A, Rugescu, I A, Vidakovic, S, Goossens, V

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Air flow control structure for use with cooling towers - with horizontal cells of specified shape and dimensions von JACQUES BOSNE ET PIERRE LUCIEN LEMMENS

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High Incidence of a Second Primary Esophageal Squamous Cell Carcinoma in Patients With Previous Head-and-Neck Cancer: A Nationwide Population-Based Study von Schotborgh, Charlotte, Liu, Lifang, Lemmens, Valery, Soerjomataram, Isabelle, Bergman, Jacques J, Schoon, Erik J

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La protection de la vie et la liberté d'expression von Lemmens, Koen

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The impact of submarine canyons and channels on primary productivity dynamics in the Lower St. Lawrence Estuary, eastern Canada von Limoges, Audrey, Jean-Montero-Serrano, Carlos, Normandeau, Alexandre, Didier, David, Bourgault, Daniel, Deslauriers, Camille, Gosselin, Michel, Lajeunesse, Patrick, Lalande, Catherine, Lemmens, Kateri, Neumeier, Urs, Rochon, Andre, Sherwood, Owen, St-Onge, Guillaume, Bernatchez, Pascal, Rondeau, Danny, Baccara, Khouloud, Bernier, Camille, Jacques, Florian, Laphengphratheng, Tina, Sharpe, Hannah

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Directed Module Detection in a Large-Scale Expression Compendium von Fu, Qiang, Lemmens, Karen, Sanchez-Rodriguez, Aminael, Thijs, Inge M., Meysman, Pieter, Sun, Hong, Fierro, Ana Carolina, Engelen, Kristof, Marchal, Kathleen

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Disparate effects of mental stress on plasma noradrenaline in young normotensive and hypertensive subjects von Lenders, Jacques W.M, Willemsen, Jacques J, de Boo, Theo, Lemmens, Wim A.J, Thien, Theo

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Rien appris, rien oublié ? von Ardila, Daniel Gutiérrez, Bensimon, Fabrice, Boudon, Jacques-Olivier, Brelot, Claude-Isabelle, Bruyère-Ostells, Walter, Caron, Jean-Claude, Chappey, Jean-Luc, Clemens, Gabriele B, Delpu, Pierre-Marie, Démier, Francis, Diaz, Delphine, Goujon, Bertrand, Herrmann, Irène, Isabella, Maurizio, Jourdan, Annie, Karila-Cohen, Pierre, Klesmann, Bernd, Lacotte, Rémy Hême de, Larroche, Emmanuel, Legoy, Corinne, Lemmens, Wim, Lignereux, Aurélien, Lok, Matthijs, Luis, Jean-Philippe, Malandain, Gilles, Nagy, Laurent, Parra, Emilio La, Petiteau, Natalie, Prida, Gonzalo Butrón, Renedo, Andoni Artola, Rey, Marie-Pierre, Rota, Arianna Arisi, Rújula, Pedro, Schönpflug, Daniel, Sellin, Volker, Tort, Olivier, Waresquiel, Emmanuel de, Yon, Jean-Claude

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Path integral approach to the pricing of timer options with the Duru-Kleinert time transformation von Liang, Ling Zhi, Lemmens, Damiaan, Tempere, Jacques

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Cardiovascular responsiveness to norepinephrine in mild essential hypertension von Lenders, Jacques W.M., De Boo, Theo, Lemmens, Wim A.J., Willemsen, Jacques J., Thien, Theo

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