Diffusion tensor imaging and Tract-Based Spatial Statistics in Alzheimer's disease and mild cognitive impairment von Liu, Yawu, Spulber, Gabriela, Lehtimäki, Kimmo K, Könönen, Mervi, Hallikainen, Ilona, Gröhn, Heidi, Kivipelto, Miia, Hallikainen, Merja, Vanninen, Ritva, Soininen, Hilkka

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Cognitive disturbances in the cuprizone model of multiple sclerosis von Kopanitsa, M, Lehtimaki, KK, Forsman, M, Suhonen, A, Koponen, J, Piiponniemi, TO, Karkkainen, A-M, Pavlidi, P, Shatillo, A, Sweeney, PJ, Merenlender-Wagner, A, Kaye, J, Orbach, A, Nurmi, A

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Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: Correlation with cell density von Valonen, Piia K., Lehtimäki, Kimmo K., Väisänen, Tuula H., Kettunen, Mikko I., Gröhn, Olli H.J., Ylä-Herttuala, Seppo, Kauppinen, Risto A.

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Novel magnetic resonance imaging contrasts for monitoring response to gene therapy in rat glioma von GRÖHN, Olli H. J, VALONEN, Piia K, LEHTIMÄKI, Kimmo K, VÄISÄNEN, Tuula H, KETTUNEN, Mikko I, YLLÄ-HERTTUALA, Seppo, KAUPPINEN, Risto A, GARWOOD, Michael

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Age-dependent association of apolipoprotein e genotype with coronary and aortic atherosclerosis in middle-aged men: An autopsy study von ILVESKOSKI, E, PEROLA, M, KOIVULA, T, KARHUNEN, P. J, LEHTIMÄKI, T, LAIPPALA, P, SAVOLAINEN, V, PAJARINEN, J, PENTTILÄ, A, LALU, K. H, MÄNNIKKÖ, A, LIESTO, K. K

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Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels von Jiang, X, O'Reilly, PF, Aschard, H, Hsu, Y-H, Richards, JB, Dupuis, J, Ingelsson, E, Karasik, D, Pilz, S, Berry, D, Kestenbaum, B, Zheng, J, Sofianopoulou, E, Streeten, EA, Albanes, D, Lutsey, PL, Yao, L, Tang, W, Econs, MJ, Wallaschofski, H, Voelzke, H, Zhou, A, Power, C, McCarthy, MI, Michos, ED, Boerwinkle, E, Weinstein, SJ, Freedman, ND, Huang, W-Y, Van Schoor, NM, Van der Velde, N, De Groot, LCPGM, Enneman, A, Cupples, LA, Booth, SL, Vasan, RS, Liu, C-T, Zhou, Y, Ripatti, S, Ohlsson, C, Vandenput, L, Eriksson, JG, Shea, MK, Houston, DK, Kritchevsky, SB, Liu, Y, Lohman, KK, Ferrucci, L, Peacock, M, Gieger, C, Beekman, M, Slagboom, E, Deelen, J, Van Heemst, D, Kleber, ME, Maerz, W, De Boer, IH, Wood, AC, Rotter, JI, Rich, SS, Robinson-Cohen, C, Den Heijer, M, Jarvelin, M-R, Cavadino, A, Joshi, PK, Wilson, JF, Hayward, C, Lind, L, Michaelsson, K, Trompet, S, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Zgaga, L, Campbell, H, Theodoratou, E, Farrington, SM, Timofeeva, M, Dunlop, MG, Valdes, AM, Tikkanen, E, Lehtimaki, T, Lyytikainen, L-P, Kahonen, M, Raitakari, OT, Mikkila, V, Ikram, MA, Sattar, N, Jukema, JW, Wareham, NJ, Langenberg, C, Forouhi, NG, Gundersen, TE, Khaw, K-T, Butterworth, AS, Danesh, J, Spector, T, Wang, TJ, Hypponen, E, Kiel, DP

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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk von Lu, Yingchang, Gustafsson, Stefan, Cousminer, Diana L., Evans, David M., Ferreira, Teresa, Hedman, Åsa K., Haring, Robin, Iles, Mark M., Kanoni, Stavroula, Li, Rui, Sanna, Marianna, Scott, William R., Teumer, Alexander, Vinkhuyzen, Anna A. E., Westra, Harm-Jan, Zhang, Weihua, Zhu, Zhihong, Bakker, Stephan J. L., Borodulin, Katja, Buchman, Aron S., Choi, Hyung Jin, Curran, Joanne E., Dhonukshe-Rutten, Rosalie A. M., Enneman, Anke W., Eury, Elodie, Fumeron, Frédéric, Garcia, Melissa E., Havulinna, Aki S., Hayward, Caroline, Hernandez, Dena, Ittermann, Till, Lahti, Jari, Leach, Irene Mateo, Lobbens, Stéphane, Lyytikäinen, Leo-Pekka, Nalls, Mike A., Oozageer, Laticia, Sarzynski, Mark A., Narančić, Nina Smolej, Spira, Dominik, Srikanth, Priya, Sung, Yun Ju, Tanaka, Toshiko, Wright, Alan F., Lichtner, Peter, Luan, Jian'an, Mahajan, Anubha, Palmer, Cameron D., Ried, Janina S., Mcknight, Barbara, Menni, Cristina, Oostra, Ben A., Song, Kijoung, Forouhi, Nita G., Grallert, Harald, Hingorani, Aroon, Jousilahti, Pekka, Laakso, Markku, Linneberg, Allan, Luke, Amy, Palotie, Aarno, Tayo, Bamidele O., Bennett, David A., Blüher, Matthias, Bouchard, Claude, Demuth, Ilja, Ferrucci, Luigi, Franco, Oscar H., Harris, Tamara B., Heliövaara, Markku, Jordan, Joanne M., Knekt, Paul B., Koskinen, Seppo, Kovacs, Peter, Liu, Yongmei, Orwoll, Eric S., Osmond, Clive, Rudan, Igor, Stumvoll, Michael, Tönjes, Anke, Towne, Bradford, Tranah, Gregory J., Uitterlinden, André G., Vohl, Marie-Claude, Walker, Mark, Wild, Sarah, Bishop, D. Timothy, Borecki, Ingrid B., Chambers, John C., Cupples, L. Adrienne, Han, Jiali, Morris, Andrew P., Bishop, Julia A. N., Ohlsson, Claes, Ong, Ken K., Spector, Tim D., Willer, Cristen J., Yang, Jian, Hirschhorn, Joel N., Zillikens, M. Carola

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Serum TRACP 5b Is a Useful Marker for Monitoring Alendronate Treatment: Comparison With Other Markers of Bone Turnover von Nenonen, Arja, Cheng, Sulin, Ivaska, Kaisa K, Alatalo, Sari L, Lehtimäki, Terho, Schmidt‐Gayk, Heinrich, Uusi‐Rasi, Kirsti, Heinonen, Ari, Kannus, Pekka, Sievänen, Harri, Vuori, Ilkka, Väänänen, H Kalervo, Halleen, Jussi M

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Inflammatory diseases, inflammatory biomarkers, and Alzheimer disease: an observational analysis and mendelian randomization von Huang, J, Su, B, Karhunen, V, Gill, D, Zuber, V, Ahola-Olli, A, Palaniswamy, S, Auvinen, J, Herzig, K-H, Keinänen-Kiukaanniemi, S, Salmi, M, Jalkanen, S, Lehtimäki, T, Salomaa, V, Raitakari, OT, Matthews, PM, Elliott, P, Tsilidis, KK, Jarvelin, M-R, Tzoulaki, I, Dehghan, A

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Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts von Vimaleswaran, KS, Berry, DJ, Lu, C, Tikkanen, E, Pilz, S, Hiraki, LT, Cooper, JD, Dastani, Z, Li, R, Houston, DK, Wood, AR, Michaelsson, K, Vandenput, L, Zgaga, L, Yerges-Armstrong, LM, McCarthy, MI, Dupuis, J, Kaakinen, M, Kleber, ME, Jameson, K, Arden, N, Raitakari, O, Viikari, J, Lohman, KK, Ferrucci, L, Melhus, H, Ingelsson, E, Byberg, L, Lind, L, Lorentzon, M, Salomaa, V, Campbell, H, Dunlop, M, Mitchell, BD, Herzig, K-H, Pouta, A, Hartikainen, A-L, Streeten, EA, Theodoratou, E, Jula, A, Wareham, NJ, Ohlsson, C, Frayling, TM, Kritchevsky, SB, Spector, TD, Richards, JB, Lehtimaki, T, Ouwehand, WH, Kraft, P, Cooper, C, Maerz, W, Power, C, Loos, RJF, Wang, TJ, Jaervelin, M-R, Whittaker, JC, Hingorani, AD, Hyppoenen, E

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DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases von Wielscher, M, Mandaviya, PR, Kuehnel, B, Joehanes, R, Mustafa, R, Robinson, O, Zhang, Y, Bodinier, B, Walton, E, Mishra, PP, Schlosser, P, Wilson, R, Tsai, P-C, Palaniswamy, S, Marioni, RE, Fiorito, G, Cugliari, G, Karhunen, V, Ghanbari, M, Psaty, BM, Loh, M, Bis, JC, Lehne, B, Sotoodehnia, N, Deary, IJ, Chadeau-Hyam, M, Brody, JA, Cardona, A, Selvin, E, Smith, AK, Miller, AH, Torres, MA, Marouli, E, Gào, X, Van Meurs, JBJ, Graf-Schindler, J, Rathmann, W, Koenig, W, Peters, A, Weninger, W, Farlik, M, Zhang, T, Chen, W, Xia, Y, Teumer, A, Nauck, M, Grabe, HJ, Doerr, M, Lehtimäki, T, Guan, W, Milani, L, Tanaka, T, Fisher, K, Waite, LL, Kasela, S, Vineis, P, Verweij, N, Van der Harst, P, Iacoviello, L, Sacerdote, C, Panico, S, Krogh, V, Tumino, R, Tzala, E, Matullo, G, Hurme, MA, Raitakari, OT, Colicino, E, Baccarelli, AA, Kähönen, M, Herzig, K-H, Li, S, BIOS consortium, Conneely, KN, Kooner, JS, Köttgen, A, Heijmans, BT, Deloukas, P, Relton, C, Ong, KK, Bell, JT, Boerwinkle, E, Elliott, P, Brenner, H, Beekman, M, Levy, D, Waldenberger, M, Chambers, JC, Dehghan, A, Järvelin, M-R

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Association of inflammatory cytokines with lung function, chronic lung diseases, and COVID-19 von Rontogianni, MO, Gill, D, Bouras, E, Asimakopoulos, A-G, Tzoulaki, I, Karhunen, V, Lehtimäki, T, Raitakari, O, Wielscher, M, Salomaa, V, Jalkanen, S, Salmi, M, Timonen, M, Yarmolinsky, J, Chen, J, Tobin, MD, Izquierdo, AG, Herzig, K-H, Ioannides, AE, Jarvelin, M-R, Dehghan, A, Tsilidis, KK

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A trans-ancestral meta-analysis of Genome-wide Association Studies reveals loci associated with childhood obesity von Bradfield, JP, Vogelezang, S, Felix, JF, Chesi, A, Helgeland, Ø, Horikoshi, M, Karhunen, V, Lowry, E, Cousminer, DL, Ahluwalia, TS, Thiering, E, Boh, ET-H, Zafarmand, MH, Vilor-Tejedor, N, Wang, CA, Joro, R, Chen, Z, Gauderman, WJ, Pitkänen, N, Parra, EJ, Fernandez-Rhodes, L, Alyass, A, Monnereau, C, Curtin, JA, Have, CT, McCormack, SE, Hollensted, M, Frithioff-Bøjsøe, C, Valladares-Salgado, A, Peralta-Romero, J, Teo, Y-Y, Standl, M, Leinonen, JT, Holm, J-C, Peters, T, Vioque, J, Vrijheid, M, Simpson, A, Custovic, A, Vaudel, M, Canouil, M, Lindi, V, Atalay, M, Kähönen, M, Raitakari, OT, Van Schaik, BDC, Berkowitz, RI, Cole, SA, Voruganti, VS, Wang, Y, Highland, HM, Comuzzie, AG, Butte, NF, Justice, AE, Gahagan, S, Blanco, E, Lehtimäki, T, Lakka, TA, Hebebrand, J, Bonnefond, A, Grarup, N, Froguel, P, Lyytikäinen, L-P, Cruz, M, Kobes, S, Hanson, RL, Zemel, BS, Hinney, A, Teo, KK, Meyre, D, North, KE, Gilliland, FD, Bisgaard, H, Bustamante, M, Bonnelykke, K, Pennell, CE, Rivadeneira, F, Uitterlinden, AG, Baier, LJ, Vrijkotte, TGM, Heinrich, J, Sørensen, TIA, Saw, S-M, Pedersen, O, Hansen, T, Eriksson, J, Widén, E, McCarthy, MI, Njølstad, PR, Power, C, Hyppönen, E, Sebert, S, Brown, CD, Järvelin, M-R, Timpson, NJ, Johansson, S, Hakonarson, H, Jaddoe, VWV, Grant, SFA, Early Growth Genetics Consortium

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Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults von Justice, AE, Hadley, D, Xue, L, Workalemahu, T, Qi, Q, Eicher, JD, Luan, J, Zhang, W, Haller, T, Yengo, L, Teumer, A, Smith, AV, Kumari, M, Lohman, K, Whitfield, JB, Zhao, JH, Wu, Y, Kristiansson, K, Demirkan, A, Navarro, P, Pasko, D, Cheng, Y-C, Lim, U, Adair, LS, Balkau, B, Beilby, J, Blangero, J, Bonnycastle, LL, Campbell, H, Collins, FS, Smith, GD, Delgado, GE, Dörr, M, Ebeling, T, Fu, M, Gieger, C, Gläser, S, Gong, J, Grallert, H, Grarup, N, Harald, K, Holmens, OL, Huang, J, Kinnunen, L, Kuusisto, J, Kvaløy, K, Lehne, B, Lorentzon, M, Monda, KL, Montgomery, GW, De Moor, MHM, Mulas, A, Musk, AW, Männistö, S, Nettleton, JA, Nolte, IM, Oldehinkel, AJ, Ong, KK, Peyser, PA, Prokopenko, I, Puolijoki, H, Rasmussen-Torvik, LJ, Scott, WR, Smith, BH, Sternfeld, B, Swift, AJ, Tammelin, T, Thuillier, D, Vestergaard, H, Waeber, G, Walker, M, Wright, AF, Haiman, CA, Ohlsson, C, Hofman, A, Rivadeneira, F, Uitterlinden, AG, Hayward, C, Polasek, O, Kardia, SLR, Tuomilehto, J, Salomaa, V, De Geus, EJC, Laakso, M, Bouchard, C, Gudnason, V, Qi, L, Järvelin, M-R, Kooperberg, C, Hansen, T, Metspalu, A, Weir, DR, Porteous, DJ, Boerwinkle, E, O'Connell, JR, Heid, IM, Mohlke, KL, Fox, CS, Klein, RJ, Johnson, AD

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Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study von Vimaleswaran, KS, Cavadino, A, Jorde, R, Dieffenbach, AK, Lu, C, Heerspink, HJL, Tikkanen, E, Eriksson, J, Wong, A, Mangino, M, Jablonski, KA, Nolte, IM, Houston, DK, Ahluwalia, TS, Van der Most, PJ, Pasko, D, Zgaga, L, Vitart, V, Fraser, RM, Huffman, JE, De Boer, RA, Schoettker, B, Saum, K-U, McCarthy, MI, Dupuis, J, Herzig, K-H, Sebert, S, Pouta, A, Laitinen, J, Kleber, ME, Navis, G, Lorentzon, M, Jameson, K, Arden, N, Cooper, JA, Acharya, J, Hardy, R, Raitakari, O, Ripatti, S, Billings, LK, Lahti, J, Osmond, C, Penninx, BW, Rejnmark, L, Lohman, KK, Paternoster, L, Stolk, RP, Hernandez, DG, Byberg, L, Hagstrom, E, Melhus, H, Ingelsson, E, Mellstroem, D, Ljunggren, O, Tzoulaki, I, McLachlan, S, Theodoratou, E, Tiesler, CMT, Jula, A, Navarro, P, Wright, AF, Polasek, O, Hayward, C, Rudan, I, Salomaa, V, Heinrich, J, Campbell, H, Price, JF, Karlsson, M, Lind, L, Michaesson, K, Bandinelli, S, Frayling, TM, Hartman, CA, Sorensen, TIA, Kritchevsky, SB, Langdahl, BL, Eriksson, JG, Florez, JC, Spector, TD, Lehtimaki, T, Kuh, D, Humphries, SE, Cooper, C, Ohlsson, C, Maerz, W, De Borst, MH, Kumari, M, Kivimaki, M, Wang, TJ, Power, C, Brenner, H, Grimnes, G, Van der Harst, P, Snieder, H, Hingorani, AD, Pilz, S, Whittaker, JC, Jarvelin, M-R, Hypponen, E

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Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels von Jiang, X, O'Reilly, PF, Aschard, H, Hsu, Y-H, Richards, JB, Dupuis, J, Ingelsson, E, Karasik, D, Pilz, S, Berry, D, Kestenbaum, B, Zheng, J, Sofianopoulou, E, Streeten, EA, Albanes, D, Lutsey, PL, Yao, L, Tang, W, Econs, MJ, Wallaschofski, H, Voelzke, H, Zhou, A, Power, C, McCarthy, MI, Michos, ED, Boerwinkle, E, Weinstein, SJ, Freedman, ND, Huang, W-Y, Van Schoor, NM, van der Velde, N, de Groot, LCPGM, Enneman, A, Cupples, LA, Booth, SL, Vasan, RS, Liu, C-T, Zhou, Y, Ripatti, S, Ohlsson, C, Vandenput, L, Eriksson, JG, Shea, MK, Houston, DK, Kritchevsky, SB, Liu, Y, Lohman, KK, Ferrucci, L, Peacock, M, Gieger, C, Beekman, M, Slagboom, E, Deelen, J, van Heemst, D, Kleber, ME, Maerz, W, de Boer, IH, Wood, AC, Rotter, JI, Rich, SS, Robinson-Cohen, C, den Heijer, M, Jarvelin, M-R, Cavadino, A, Joshi, PK, Wilson, JF, Hayward, C, Lind, L, Michaelsson, K, Trompet, S, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Zgaga, L, Campbell, H, Theodoratou, E, Farrington, SM, Timofeeva, M, Dunlop, MG, Valdes, AM, Tikkanen, E, Lehtimaki, T, Lyytikainen, L-P, Kahonen, M, Raitakari, OT, Mikkila, V, Ikram, MA, Sattar, N, Jukema, JW, Wareham, NJ, Langenberg, C, Forouhi, NG, Gundersen, TE, Khaw, K-T, Butterworth, AS, Danesh, J, Spector, T, Wang, TJ, Hypponen, E, Kiel, DP

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Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis von Bouras, E, Karhunen, V, Gill, D, Huang, J, Haycock, PC, Gunter, MJ, Johansson, M, Brennan, P, Key, T, Lewis, SJ, Martin, RM, Murphy, N, Platz, EA, Travis, R, Yarmolinsky, J, Zuber, V, Martin, P, Katsoulis, M, Freisling, H, Nøst, TH, Schulze, MB, Dossus, L, Hung, RJ, Amos, CI, Ahola-Olli, A, Palaniswamy, S, Männikkö, M, Auvinen, J, Herzig, K-H, Keinänen-Kiukaanniemi, S, Lehtimäki, T, Salomaa, V, Raitakari, O, Salmi, M, Jalkanen, S, PRACTICAL consortium, Jarvelin, M-R, Dehghan, A, Tsilidis, KK

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Meta-analysis of epigenome-wide association studies of carotid intima-media thickness von Portilla-Fernández, E, Hwang, S-J, Wilson, R, Maddock, J, Hill, WD, Teumer, A, Mishra, PP, Brody, JA, Joehanes, R, Ligthart, S, Ghanbari, M, Kavousi, M, Roks, AJM, Danser, AHJ, Levy, D, Peters, A, Ghasemi, S, Schminke, U, Dörr, M, Grabe, HJ, Lehtimäki, T, Kähönen, M, Hurme, MA, Bartz, TM, Sotoodehnia, N, Bis, JC, Thiery, J, Koenig, W, Ong, KK, Bell, JT, Meisinger, C, Wardlaw, JM, Starr, JM, Seissler, J, Then, C, Rathmann, W, Ikram, MA, Psaty, BM, Raitakari, OT, Völzke, H, Deary, IJ, Wong, A, Waldenberger, M, O'Donnell, CJ, Dehghan, A

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Additional file 2 of Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis von Bouras, E, Karhunen, V, Gill, D, Huang, J, Haycock, PC, Gunter, MJ, Johansson, M, Brennan, P, Key, T, Lewis, SJ, Martin, RM, Murphy, N, Platz, EA, Travis, R, Yarmolinsky, J, Zuber, V, Martin, P, Katsoulis, M, Freisling, H, Haugdahl Nøst, T, Schulze, MB, Dossus, L, Hung, RJ, Amos, CI, Ahola-Olli, A, Palaniswamy, S, Männikkö, M, Auvinen, J, Herzig, K-H, Keinänen-Kiukaanniemi, S, Lehtimäki, T, Salomaa, V, Raitakari, O, Salmi, M, Jalkanen, S, Jarvelin, M-R, Dehghan, A, Tsilidis, KK

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Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults von Justice, AE, Hadley, D, Xue, L, Workalemahu, T, den Hoed, M, Qi, Q, Eicher, JD, Luan, J, Zhang, W, Haller, T, Yengo, L, Teumer, A, Smith, AV, Kumari, M, Lohman, K, Whitfield, JB, Zhao, JH, Wu, Y, Kristiansson, K, Demirkan, A, Navarro, P, Pasko, D, Cheng, Y-C, Lim, U, Adair, LS, Balkau, B, Beilby, J, Blangero, J, Bonnycastle, LL, Campbell, H, Collins, FS, Smith, GD, Delgado, GE, Dörr, M, Ebeling, T, Fu, M, Gieger, C, Gläser, S, Gong, J, Grallert, H, Grarup, N, Harald, K, Holmens, OL, Huang, J, Kinnunen, L, Kuusisto, J, Kvaløy, K, Lorentzon, M, Monda, KL, Montgomery, GW, De Moor, MHM, Mulas, A, Musk, AW, Männistö, S, Nettleton, JA, Nolte, IM, Oldehinkel, AJ, Ong, KK, Peyser, PA, Prokopenko, I, Puolijoki, H, Rasmussen-Torvik, LJ, Smith, BH, Sternfeld, B, Swift, AJ, Tammelin, T, Thuillier, D, Vestergaard, H, Waeber, G, Walker, M, Wright, AF, Haiman, CA, Ohlsson, C, Hofman, A, Rivadeneira, F, Uitterlinden, AG, Hayward, C, Polasek, O, Kardia, SLR, Tuomilehto, J, Salomaa, V, de Geus, EJC, Laakso, M, Bouchard, C, Gudnason, V, Qi, L, Järvelin, M-R, Kooperberg, C, Hansen, T, Metspalu, A, Weir, DR, Porteous, DJ, Boerwinkle, E, O'Connell, JR, van Duijn, CM, Heid, IM, Mohlke, KL, Fox, CS, Klein, RJ, Johnson, AD

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