Structure of the core human NADPH oxidase NOX2 von Noreng, Sigrid, Ota, Naruhisa, Sun, Yonglian, Ho, Hoangdung, Johnson, Matthew, Arthur, Christopher P., Schneider, Kellen, Lehoux, Isabelle, Davies, Christopher W., Mortara, Kyle, Wong, Kit, Seshasayee, Dhaya, Masureel, Matthieu, Payandeh, Jian, Yi, Tangsheng, Koerber, James T.

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A Platform for Extracellular Interactome Discovery Identifies Novel Functional Binding Partners for the Immune Receptors B7-H3/CD276 and PVR/CD155 von Husain, Bushra, Ramani, Sree R., Chiang, Eugene, Lehoux, Isabelle, Paduchuri, Sairupa, Arena, Tia A., Patel, Ashka, Wilson, Blair, Chan, Pamela, Franke, Yvonne, Wong, Athena W., Lill, Jennie R., Turley, Shannon J., Gonzalez, Lino C., Grogan, Jane L., Martinez-Martin, Nadia

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HPK1 citron homology domain regulates phosphorylation of SLP76 and modulates kinase domain interaction dynamics von Chitre, Avantika S., Wu, Ping, Walters, Benjamin T., Wang, Xiangdan, Bouyssou, Alexandre, Du, Xiangnan, Lehoux, Isabelle, Fong, Rina, Arata, Alisa, Chan, Joyce, Wang, Die, Franke, Yvonne, Grogan, Jane L., Mellman, Ira, Comps-Agrar, Laetitia, Wang, Weiru

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Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection von Luchetti, Giovanni, Roncaioli, Justin L., Chavez, Roberto A., Schubert, Alexander F., Kofoed, Eric M., Reja, Rohit, Cheung, Tommy K., Liang, Yuxin, Webster, Joshua D., Lehoux, Isabelle, Skippington, Elizabeth, Reeder, Janina, Haley, Benjamin, Tan, Man Wah, Rose, Christopher M., Newton, Kim, Kayagaki, Nobuhiko, Vance, Russell E., Dixit, Vishva M.

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Antibody targeting of E3 ubiquitin ligases for receptor degradation von Marei, Hadir, Tsai, Wen-Ting K., Kee, Yee-Seir, Ruiz, Karen, He, Jieyan, Cox, Chris, Sun, Tao, Penikalapati, Sai, Dwivedi, Pankaj, Choi, Meena, Kan, David, Saenz-Lopez, Pablo, Dorighi, Kristel, Zhang, Pamela, Kschonsak, Yvonne T., Kljavin, Noelyn, Amin, Dhara, Kim, Ingrid, Mancini, Andrew G., Nguyen, Thao, Wang, Chunling, Janezic, Eric, Doan, Alexander, Mai, Elaine, Xi, Hongkang, Gu, Chen, Heinlein, Melanie, Biehs, Brian, Wu, Jia, Lehoux, Isabelle, Harris, Seth, Comps-Agrar, Laetitia, Seshasayee, Dhaya, de Sauvage, Frederic J., Grimmer, Matthew, Li, Jing, Agard, Nicholas J., de Sousa e Melo, Felipe

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The Immunoglobulin Superfamily Receptome Defines Cancer-Relevant Networks Associated with Clinical Outcome von Verschueren, Erik, Husain, Bushra, Yuen, Kobe, Sun, Yi, Paduchuri, Sairupa, Senbabaoglu, Yasin, Lehoux, Isabelle, Arena, Tia A., Wilson, Blair, Lianoglou, Steve, Bakalarski, Corey, Franke, Yvonne, Chan, Pamela, Wong, Athena W., Gonzalez, Lino C., Mariathasan, Sanjeev, Turley, Shannon J., Lill, Jennie R., Martinez-Martin, Nadia

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Activation of the Interleukin-18 Signaling Pathway via Direct Receptor Dimerization in the Absence of Interleukin-18 von Mortazavi, Yasaman, Herrera, Robert, Masureel, Matthieu, Maculins, Timurs, Lehoux, Isabelle, Sockolosky, Jonathan, West, Nathan, Bulutoglu, Beyza, Zhao, Yue

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Role of Arginine 277 in (S)-Mandelate Dehydrogenase from Pseudomonas putida in Substrate Binding and Transition State Stabilization von Lehoux, Isabelle E, Mitra, Bharati

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Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer von Wu, Ping, Sneeringer, Christopher J., Pitts, Keith E., Day, Eric S., Chan, Bryan K., Wei, Binqing, Lehoux, Isabelle, Mortara, Kyle, Li, Hong, Wu, Jiansheng, Franke, Yvonne, Moffat, John G., Grogan, Jane L., Heffron, Timothy P., Wang, Weiru

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(S)-Mandelate Dehydrogenase from Pseudomonas putida: Mechanistic Studies with Alternate Substrates and pH and Kinetic Isotope Effects von Lehoux, Isabelle E, Mitra, Bharati

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IL-27 elicits a cytotoxic CD8 + T cell program to enforce tumour control von Bréart, Béatrice, Williams, Katherine, Krimm, Stellanie, Wong, Tiffany, Kayser, Brandon D, Wang, Lifen, Cheng, Eric, Cruz Tleugabulova, Mayra, Bouziat, Romain, Lu, Tianshi, Yuen, Kobe, Firmino, Natalie S, Bravo, Daniel D, Roels, Juliette, Bhakta, Atish, Bevers, 3rd, Jack, Lehoux, Isabelle, Gutierrez, Alan, Chestnut, Yajun, Klementowicz, Joanna E, Arenzana, Teresita L, Akhmetzyanova, Ilseyar, Dixon, Elizabeth, Chen, Min, Tasneem, Kazi, Yadav, Rajbharan, Koeppen, Hartmut, Oh, Soyoung A, Delamarre, Lélia, Huang, Haochu, Lim, Shion A, Nakamura, Gerald, Wang, Jianyong, Gao, Chan, Corpuz, Racquel, Müller, Sören, West, Nathaniel R

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Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer von Wu, Ping, Sneeringer, Christopher J., Pitts, Keith E., Day, Eric S., Chan, Bryan K., Wei, Binqing, Lehoux, Isabelle, Mortara, Kyle, Li, Hong, Wu, Jiansheng, Franke, Yvonne, Moffat, John G., Grogan, Jane L., Heffron, Timothy P., Wang, Weiru

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Purification and characterization of YihA, an essential GTP-binding protein from Escherichia coli von Lehoux, Isabelle E, Mazzulla, Marie J, Baker, Audrey, Petit, Chantal M

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Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR) von Takeuchi, Craig S, Kim, Byung Gyu, Blazey, Charles M, Ma, Sunghoon, Johnson, Henry W. B, Anand, Neel K, Arcalas, Arlyn, Baik, Tae Gon, Buhr, Chris A, Cannoy, Jonah, Epshteyn, Sergey, Joshi, Anagha, Lara, Katherine, Lee, Matthew S, Wang, Longcheng, Leahy, James W, Nuss, John M, Aay, Naing, Aoyama, Ron, Foster, Paul, Lee, Jae, Lehoux, Isabelle, Munagala, Narsimha, Plonowski, Arthur, Rajan, Sharmila, Woolfrey, John, Yamaguchi, Kyoko, Lamb, Peter, Miller, Nicole

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Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy von Chang, Joshua C., Durinck, Steffen, Chen, Mark Z., Martinez-Martin, Nadia, Zhang, Jingli A., Lehoux, Isabelle, Li, Hong, Lin, May, Wu, Jiansheng, Bainbridge, Travis W., Ernst, James A., Ramani, Sree R., Paduchuri, Sairupa, Kates, Lance, Solon, Margaret, Buechler, Matthew B., Castiglioni, Alessandra, Thai, Minh, Breart, Beatrice, Modrusan, Zora, Peterson, Andrew S., Turley, Shannon J., Sonoda, Junichiro

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(S)-Mandelate Dehydrogenase from Pseudomonas putida:  Mutations of the Catalytic Base Histidine-274 and Chemical Rescue of Activity von Lehoux, Isabelle E, Mitra, Bharati

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Semiautomated Small-Scale Purification Method for High-Throughput Expression Analysis of Recombinant Proteins von Kraft, Edward, Franke, Yvonne, Heeringa, Katharine, Shriver, Stephanie, Zilberleyb, Inna, Kugel, Christine, Dela Vega, Trisha, Wong, Athena, Brillantes, Bobby, Ciferri, Claudio, Dutina, George, Lee, Grace, Lehoux, Isabelle, Li, Zhong Rong, Lior-Hoffmann, Lee, Hwang, Jiyoung, Lonergan, Chris, Martin, Lynn, Mortara, Kyle, Nguyen, Lananh, Payandeh, Jian, Perez, Andrew, Sampang, Jun, Singh, Lovejit, Schroeder, Kurt, Tam, Christine, Ti, Shu, Win, Ye Naing, Bowman, Krista

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Quinolones as HCV NS5B polymerase inhibitors von Kumar, Dange V., Rai, Roopa, Brameld, Ken A., Somoza, John R., Rajagopalan, Ravi, Janc, James W., Xia, Yu M., Ton, Tony L., Shaghafi, Michael B., Hu, Huiyong, Lehoux, Isabelle, To, Nhat, Young, Wendy B., Green, Michael J.

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A Platform for Extracellular Interactome Discovery Identifies Novel Functional Binding Partners for the Immune Receptors B7-H3/CD276 and PVR/CD155 von Husain, Bushra, Ramani, Sree R, Chiang, Eugene, Lehoux, Isabelle, Paduchuri, Sairupa, Arena, Tia A, Patel, Ashka, Wilson, Blair, Chan, Pamela, Franke, Yvonne, Wong, Athena W, Lill, Jennie R, Turley, Shannon J, Gonzalez, Lino C, Grogan, Jane L, Martinez-Martin, Nadia

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3-Heterocyclyl quinolone inhibitors of the HCV NS5B polymerase von Kumar, Dange V., Rai, Roopa, Brameld, Ken A., Riggs, Jennifer, Somoza, John R., Rajagopalan, Ravi, Janc, James W., Xia, Yu M., Ton, Tony L., Hu, Huiyong, Lehoux, Isabelle, Ho, Joseph D., Young, Wendy B., Hart, Barry, Green, Michael J.

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