Phosphodiesterase type IV (PDE IV) inhibition. Synthesis and evaluation of a series of 1,3,4-trisubstituted pyrrolidines von Stafford, Jeffrey A, Valvano, Nicole L, Feldman, Paul L, Sloan Brawley, E, Cowan, David J, Domanico, Paul L, Leesnitzer, Michael A, Rose, Dudley A, Stimpson, Stephen A, Strickland, Alan B, Unwalla, Rayomand J, Verghese, Margrith W

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Phosphodiesterase Type IV Inhibition. Structure-Activity Relationships of 1,3-Disubstituted Pyrrolidines von Feldman, Paul L, Brackeen, Marcus F, Cowan, David J, Marron, Brian E, Schoenen, Frank J, Stafford, Jeffrey A, Suh, Edward M, Domanico, Paul L, Rose, Dudley

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Two-dimensional diffusion of F1F0-ATP synthase and ADP/ATP translocator. Testing a hypothesis for ATP synthesis in the mitochondrial inner membrane von GUPTE, S. S, CHAZOTTE, B, LEESNITZER, M. A, HACKENBROCK, C. R

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Structure-activity relationships involving the catechol subunit of rolipram von Stafford, Jeffrey A., Feldman, Paul L., Marron, Brian E., Schoenen, Frank J., Valvano, Nicole L., Unwalla, Rayomand J., Domanico, Paul L., Brawley, E.Sloan, Leesnitzer, Michael A., Rose, Dudley A., Dougherty, Robert W.

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Two-dimensional diffusion of F 1F 0-ATP synthase and ADP/ATP translocator. Testing a hypothesis for ATP synthesis in the mitochondrial inner membrane von Gupte, Sharmila Shaila, Chazotte, Brad, Leesnitzer, Michael A., Hackenbrock, Charles R.

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The Novel Synthetic Triterpenoid, CDDO-Imidazolide, Inhibits Inflammatory Response and Tumor Growth in Vivo von PLACE, Andrew E, NANJOO SUH, ROSEN, Evan, SPORN, Michael B, WILLIAMS, Charlotte R, RISINGSONG, Renee, HONDA, Tadashi, HONDA, Yukiko, GRIBBLE, Gordon W, LEESNITZER, Lisa M, STIMMEL, Julie B, WILLSON, Timothy M

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A Synthetic Triterpenoid, 2-Cyano-3,12-dioxooleana-1,9-dien-28-oic Acid (CDDO), Is a Ligand for the Peroxisome Proliferator-Activated Receptor γ von Wang, Yongping, Porter, Weston W, Suh, Nanjoo, Honda, Tadashi, Gribble, Gordon W, Leesnitzer, Lisa M, Plunket, Kelli D, Mangelsdorf, David J, Blanchard, Steven G, Willson, Timothy M, Sporn, Michael B

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Identification and Characterization of 4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a Selective and Irreversible Peroxisome Proliferator-Activat... von Shearer, Barry G, Wiethe, Robert W, Ashe, Adam, Billin, Andrew N, Way, James M, Stanley, Thomas B, Wagner, Craig D, Xu, Robert X, Leesnitzer, Lisa M, Merrihew, Raymond V, Shearer, Todd W, Jeune, Michael R, Ulrich, John C, Willson, Timothy M

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Design of Selective and Soluble Inhibitors of Tumor Necrosis Factor-α Converting Enzyme (TACE) von Rabinowitz, Michael H, Andrews, Robert C, Becherer, J. David, Bickett, D. Mark, Bubacz, Dulce G, Conway, James G, Cowan, David J, Gaul, Micheal, Glennon, Kimberly, Lambert, Millard H, Leesnitzer, M. Anthony, McDougald, Darryl L, Moss, Marcia L, Musso, David L, Rizzolio, Michele C

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Identification and Characterization of 4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethylbenzamide (GSK3787), a Selective and Irreversible Peroxisome Proliferator-Activate... von SHEARER, Barry G, WIETHE, Robert W, SHEARER, Todd W, JEUNE, Michael R, ULRICH, John C, WILLSON, Timothy M, ASHE, Adam, BILLIN, Andrew N, WAY, James M, STANLEY, Thomas B, WAGNER, Craig D, XU, Robert X, LEESNITZER, Lisa M, MERRIHEW, Raymond V

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N-Hydroxyformamide peptidomimetics as TACE/Matrix metalloprotease inhibitors: oral activity via P1′ isobutyl substitution von Musso, David L., Andersen, Marc W., Andrews, Robert C., Austin, Richard, Beaudet, Elizabeth J., Becherer, J.David, Bubacz, Dulce G., Bickett, D.Mark, Chan, Joseph H., Conway, James G., Cowan, David J., Gaul, Michael D., Glennon, Kimberly C., Hedeen, Kevin M., Lambert, Millard H., Leesnitzer, M.Anthony, McDougald, Darryl L., Mitchell, Justin L., Moss, Marcia L., Rabinowitz, Michael H., Rizzolio, Michele C., Schaller, Lee T., Stanford, Jennifer B., Tippin, Timothy K., Warner, Janet R., Whitesell, L.Graham, Wiethe, Robert W.

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