Prediction of CYP2D6 phenotype from genotype across world populations von Gaedigk, Andrea, Sangkuhl, Katrin, Whirl-Carrillo, Michelle, Klein, Teri, Leeder, J. Steven

Volltext

Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy von Brown, Jacob T., Bishop, Jeffrey R., Sangkuhl, Katrin, Nurmi, Erika L., Mueller, Daniel J., Dinh, Jean C., Gaedigk, Andrea, Klein, Teri E., Caudle, Kelly E., McCracken, James T., Leon, Jose, Leeder, J. Steven

Volltext

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database von Gaedigk, Andrea, Ingelman‐Sundberg, Magnus, Miller, Neil A., Leeder, J. Steven, Whirl‐Carrillo, Michelle, Klein, Teri E.

Volltext

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors von Hicks, JK, Bishop, JR, Sangkuhl, K, Müller, DJ, Ji, Y, Leckband, SG, Leeder, JS, Graham, RL, Chiulli, DL, LLerena, A, Skaar, TC, Scott, SA, Stingl, JC, Klein, TE, Caudle, KE, Gaedigk, A

Volltext

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing von Birdwell, KA, Decker, B, Barbarino, JM, Peterson, JF, Stein, CM, Sadee, W, Wang, D, Vinks, AA, He, Y, Swen, JJ, Leeder, JS, van Schaik, RHN, Thummel, KE, Klein, TE, Caudle, KE, MacPhee, IAM

Volltext

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin Reuptake Inhibitor Antidepressants von Bousman, Chad A., Stevenson, James M., Ramsey, Laura B., Sangkuhl, Katrin, Hicks, J. Kevin, Strawn, Jeffrey R., Singh, Ajeet B., Ruaño, Gualberto, Mueller, Daniel J., Tsermpini, Evangelia Eirini, Brown, Jacob T., Bell, Gillian C., Leeder, J. Steven, Gaedigk, Andrea, Scott, Stuart A., Klein, Teri E., Caudle, Kelly E., Bishop, Jeffrey R.

Volltext

Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics von Prasad, B, Gaedigk, A, Vrana, M, Gaedigk, R, Leeder, JS, Salphati, L, Chu, X, Xiao, G, Hop, CECA, Evers, R, Gan, L, Unadkat, JD

Volltext

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update von Crews, K R, Gaedigk, A, Dunnenberger, H M, Leeder, J S, Klein, T E, Caudle, K E, Haidar, C E, Shen, D D, Callaghan, J T, Sadhasivam, S, Prows, C A, Kharasch, E D, Skaar, T C

Volltext

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy von Crews, Kristine R., Monte, Andrew A., Huddart, Rachel, Caudle, Kelly E., Kharasch, Evan D., Gaedigk, Andrea, Dunnenberger, Henry M., Leeder, J. Steven, Callaghan, John T., Samer, Caroline Flora, Klein, Teri E., Haidar, Cyrine E., Van Driest, Sara L., Ruano, Gualberto, Sangkuhl, Katrin, Cavallari, Larisa H., Müller, Daniel J., Prows, Cynthia A., Nagy, Mohamed, Somogyi, Andrew A., Skaar, Todd C.

Volltext

Who Believes They Are “Just Average”: Informing the Treatment of Individual Patients Using Population Data von Leeder, J. Steven

Volltext

The CYP2D6 Activity Score: Translating Genotype Information into a Qualitative Measure of Phenotype von Gaedigk, A, Simon, SD, Pearce, RE, Bradford, LD, Kennedy, MJ, Leeder, JS

Volltext

Recent advances in the ontogeny of drug disposition von Chapron, Brian D., Chapron, Alenka, Leeder, J. Steven

Volltext

Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver von Bhatt, Deepak Kumar, Mehrotra, Aanchal, Gaedigk, Andrea, Chapa, Revathi, Basit, Abdul, Zhang, Haeyoung, Choudhari, Prachi, Boberg, Mikael, Pearce, Robin E., Gaedigk, Roger, Broeckel, Ulrich, Leeder, J. Steven, Prasad, Bhagwat

Volltext

Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother von Koren, Gideon, Cairns, James, Chitayat, David, Gaedigk, Andrea, Leeder, Steven J

Volltext

Identifying Effective Treatments for Dystonia in Patients with Cerebral Palsy: A Precision Therapeutics Approach von Gelineau-Morel, Rose, Smyser, Christopher, Leeder, J Steven

Volltext

Aprepitant and fosaprepitant drug interactions: a systematic review von Patel, Priya, Leeder, J. Steven, Piquette‐Miller, Micheline, Dupuis, L. Lee

Volltext

Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics von Gaedigk, Andrea, Dinh, Jean C, Jeong, Hyunyoung, Prasad, Bhagwat, Leeder, J Steven

Volltext

Response to “What is the Current Clinical Impact of the CYP2C:TG Haplotype?” von Zubiaur, Pablo, Leeder, J. Steven, Abad‐Santos, Francisco, Gaedigk, Andrea

Volltext

Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver von Leeder, J Steven, Dinh, Jean C, Gaedigk, Andrea, Staggs, Vincent S, Prasad, Bhagwat, Pearce, Robin E

Volltext

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infant... von Boberg, Mikael, Vrana, Marc, Mehrotra, Aanchal, Pearce, Robin E., Gaedigk, Andrea, Bhatt, Deepak Kumar, Leeder, J. Steven, Prasad, Bhagwat

Volltext