Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms von Pridgeon, Chris S., Schlott, Constanze, Wong, Min Wei, Heringa, Minne B., Heckel, Tobias, Leedale, Joe, Launay, Laurence, Gryshkova, Vitalina, Przyborski, Stefan, Bearon, Rachel N., Wilkinson, Emma L., Ansari, Tahera, Greenman, John, Hendriks, Delilah F. G., Gibbs, Sue, Sidaway, James, Sison-Young, Rowena L., Walker, Paul, Cross, Mike J., Park, B. Kevin, Goldring, Chris E. P.

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P17-04 An automated tool for selection of chemical analogues to facilitate development of new physiologically-based kinetic models using a read-across approach von Thompson, C.V., Webb, S.D., Leedale, J., Penson, P.E., Paini, A., Ebbrell, D., Madden, J.C.

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Systems Toxicology Approach to Identifying Paracetamol Overdose von Mason, Chantelle L., Leedale, Joseph, Tasoulis, Sotiris, Jarman, Ian, Antoine, Daniel J., Webb, Steven D.

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A mathematical investigation into the uptake kinetics of nanoparticles in vitro von West, H, Roberts, F, Sweeney, P, Walker-Samuel, S, Leedale, J, Colley, H, Murdoch, C, Shipley, R.J, Webb, S

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A mathematical investigation into the uptake kinetics of nanoparticles in vitro von West, H, Roberts, F, Sweeney, P, Walker-Samuel, S, Leedale, J, Colley, H, Murdoch, C, Shipley, RJ, Webb, S

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In silico-guided optimisation of oxygen gradients in hepatic spheroids von Leedale, J, Colley, H.E, Gaskell, H, Williams, D.P, Bearon, R.N, Chadwick, A.E, Murdoch, C, Webb, S.D

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Preparation of primary rat hepatocyte spheroids utilizing the liquid‐overlay technique von Kyffin, J.A, Cox, C.R, Leedale, J, Colley, H.E, Murdoch, C, Mistry, P, Webb, S.D, Sharma, P

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Characterisation of a functional rat hepatocyte spheroid model von Kyffin, J.A, Sharma, P, Leedale, J, Colley, H.E, Murdoch, C, Harding, A.L, Mistry, P, Webb, S.D

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Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment von Kyffin, J.A, Sharma, P, Leedale, J, Colley, H.E, Murdoch, C, Mistry, P, Webb, S.D

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Defining skin xenobiotic metabolism using a combined in vitro/in silico approach von Webb, S, Sharma, P, Colley, H.E, Sneddon, A, Shipley, R, Leedale, J, Smith, S, Murdoch, C

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A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity von Leedale, J, Sharkey, K.J, Colley, H.E, Norton, Á.M, Peeney, D, Mason, C.L, Sathish, J.G, Murdoch, C, Sharma, P, Webb, S.D

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Fine‐scale genetic structure and helping decisions in a cooperatively breeding bird von Leedale, Amy E., Sharp, Stuart P., Simeoni, Michelle, Robinson, Elva J. H., Hatchwell, Ben J.

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Helping decisions and kin recognition in long-tailed tits: is call similarity used to direct help towards kin? von Leedale, Amy E., Lachlan, Robert F., Robinson, Elva J. H., Hatchwell, Ben J.

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Coordination of care by breeders and helpers in the cooperatively breeding long-tailed tit von Halliwell, Chay, Beckerman, Andrew P, Germain, Marion, Patrick, Samantha C, Leedale, Amy E, Hatchwell, Ben J

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Cost, risk, and avoidance of inbreeding in a cooperatively breeding bird von Leedale, Amy E., Simeoni, Michelle, Sharp, Stuart P., Green, Jonathan P., Slate, Jon, Lachlan, Robert F., Robinson, Elva J. H., Hatchwell, Ben J.

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A mathematical investigation into the uptake kinetics of nanoparticles in vitro von West, Hannah, Roberts, Fiona, Sweeney, Paul, Walker-Samuel, Simon, Leedale, Joseph, Colley, Helen, Murdoch, Craig, Shipley, Rebecca J., Webb, Steven

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Kith or Kin? Familiarity as a Cue to Kinship in Social Birds von Leedale, Amy E., Li, Jianqiang, Hatchwell, Ben J.

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Modelling changes in glutathione homeostasis as a function of quinone redox metabolism von Kelly, Ross A., Leedale, Joseph, Calleja, Dominic, Enoch, Steven J., Harrell, Andy, Chadwick, Amy E., Webb, Steven

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Tight Control of Hypoxia-inducible Factor-α Transient Dynamics Is Essential for Cell Survival in Hypoxia von Bagnall, James, Leedale, Joseph, Taylor, Sarah E., Spiller, David G., White, Michael R.H., Sharkey, Kieran J., Bearon, Rachel N., Sée, Violaine

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A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity von Leedale, Joseph, Sharkey, Kieran J., Colley, Helen E., Norton, Áine M., Peeney, David, Mason, Chantelle L., Sathish, Jean G., Murdoch, Craig, Sharma, Parveen, Webb, Steven D.

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