Heat Shock Protein 90: Inhibitors in Clinical Trials von Biamonte, Marco A, Van de Water, Ryan, Arndt, Joseph W, Scannevin, Robert H, Perret, Daniel, Lee, Wen-Cherng

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Small Molecular Inhibitor of Transforming Growth Factor-β Protects Against Development of Radiation-Induced Lung Injury von Anscher, Mitchell S., M.D, Thrasher, Bradley, Zgonjanin, Larisa, Rabbani, Zahid N., M.D, Corbley, Michael J., Ph.D, Fu, Kai, Ph.D, Sun, Lihong, Ph.D, Lee, Wen-Cherng, Ph.D, Ling, Leona E., Ph.D, Vujaskovic, Zeljko, M.D., Ph.D

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A modified Curtius reaction: an efficient and simple method for direct isolation of free amine von Ma, Bin, Lee, Wen-Cherng

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The small molecule TGF-β signaling inhibitor SM16 synergizes with agonistic OX40 antibody to suppress established mammary tumors and reduce spontaneous metastasis von Garrison, Kendra, Hahn, Tobias, Lee, Wen-Cherng, Ling, Leona E., Weinberg, Andrew D., Akporiaye, Emmanuel T.

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Strategies for TGF-β modulation: a review of recent patents von Bonafoux, Dominique, Lee, Wen-Cherng

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Stereochemistry–activity relationship of orally active tetralin S1P agonist prodrugs von Ma, Bin, Guckian, Kevin M., Lin, Edward Yin-Shiang, Lee, Wen-Cherng, Scott, Daniel, Kumaravel, Gnanasambandam, Macdonald, Timothy L., Lynch, Kevin R., Black, Cheryl, Chollate, Sowmya, Hahm, Kyungmin, Hetu, Gregg, Jin, Ping, Luo, Yi, Rohde, Ellen, Rossomando, Anthony, Scannevin, Robert, Wang, Joy, Yang, Chunhua

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Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery von Erlanson, Daniel A., Arndt, Joseph W., Cancilla, Mark T., Cao, Kathy, Elling, Robert A., English, Nicki, Friedman, Jessica, Hansen, Stig K., Hession, Cathy, Joseph, Ingrid, Kumaravel, Gnanasambandam, Lee, Wen-Cherng, Lind, Ken E., McDowell, Robert S., Miatkowski, Konrad, Nguyen, Christine, Nguyen, Thinh B., Park, Sophia, Pathan, Nuzhat, Penny, David M., Romanowski, Michael J., Scott, Daniel, Silvian, Laura, Simmons, Robert L., Tangonan, Bradley T., Yang, Wenjin, Sun, Lihong

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A novel small-molecule inhibitor of transforming growth factor β type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after... von SUZUKI, Eiji, KIM, Samuel, LING, Leona E, CHEUNG, H.-Kam, CORBLEY, Michael J, XIAMEI ZHANG, LIHONG SUN, FENG SHAN, SINGH, Juswinder, LEE, Wen-Cherng, ALBELDA, Steven M

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Intracellular TGF-β Receptor Blockade Abrogates Smad-Dependent Fibroblast Activation In Vitro and In Vivo von Ishida, Wataru, Mori, Yasuji, Lakos, Gabriella, Sun, Lihong, Shan, Feng, Bowes, Scott, Josiah, Serene, Lee, Wen-Cherng, Singh, Juswinder, Ling, Leona E., Varga, John

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A Kinase-focused Compound Collection: Compilation and Screening Strategy von Sun, Dongyu, Chuaqui, Claudio, Deng, Zhan, Bowes, Scott, Chin, Donovan, Singh, Juswinder, Cullen, Patrick, Hankins, Gretchen, Lee, Wen-Cherng, Donnelly, Jason, Friedman, Jessica, Josiah, Serene

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An Abiotic Strategy for the Enantioselective Synthesis of Erythromycin B von Hergenrother, Paul J., Hodgson, Anne, Judd, Andrew S., Lee, Wen-Cherng, Martin, Stephen F.

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Duplexed, bead‐based competitive assay for inhibitors of protein kinases von Simons, Peter C., Young, Susan M., Gibaja, Veronica, Lee, Wen‐Cherng, Josiah, Serene, Edwards, Bruce S., Sklar, Larry A.

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SM16, an Orally Active TGF-β Type I Receptor Inhibitor Prevents Myofibroblast Induction and Vascular Fibrosis in the Rat Carotid Injury Model von Fu, Kai, Corbley, Michael J, Sun, Lihong, Friedman, Jessica E, Shan, Feng, Papadatos, James L, Costa, Donald, Lutterodt, Frank, Sweigard, Harry, Bowes, Scott, Choi, Michael, Boriack-Sjodin, P Ann, Arduini, Robert M, Sun, Dongyu, Newman, Miki N, Zhang, Xiamei, Mead, Jonathan N, Chuaqui, Claudio E, Cheung, H-Kam, Zhang, Xin, Cornebise, Mark, Carter, Mary Beth, Josiah, Serene, Singh, Juswinder, Lee, Wen-Cherng, Gill, Alan, Ling, Leona E

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Pyrazolone based TGFβR1 kinase inhibitors von Guckian, Kevin, Carter, Mary Beth, Lin, Edward Yin-Shiang, Choi, Michael, Sun, Lihong, Boriack-Sjodin, P. Ann, Chuaqui, Claudio, Lane, Benjamin, Cheung, Kam, Ling, Leona, Lee, Wen-Cherng

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Successful shape-based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI) von JUSWINDER SINGH, CHUAQUI, Claudio E, PAPADATOS, James L, BOWES, Scott, JOSIAH, Serene, LING, Leona E, BORIACK-SJODIN, P. Ann, LEE, Wen-Cherng, PONTZ, Timothy, CORBLEY, Michael J, CHEUNG, H.-Kam, ARDUINI, Robert M, MEAD, Jonathan N, NEWMAN, Miki N

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Total synthesis of erythromycin B von Breton, Philippe, Hergenrother, Paul J., Hida, Tsuneaki, Hodgson, Anne, Judd, Andrew S., Kraynack, Erica, Kym, Philip R., Lee, Wen-Cherng, Loft, Michael S., Yamashita, Masayuki, Martin, Stephen F.

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An Orally Active Small Molecule TGF-β Receptor I Antagonist Inhibits the Growth of Metastatic Murine Breast Cancer von RAUNCH, Matthew P, HAHN, Tobias, LEE, Wen-Cherng, LING, Leona E, AKPORIAYE, Emmanuel T, RAMANATHAPURAM, Lalitha, BRADLEY-DUNLOP, Deborah, MAHADEVAN, Daruka, MERCADO-PIMENTEL, Melania E, RUNYAN, Raymond B, BESSELSEN, David G, XIAMEI ZHANG, CHEUNG, H.-Kam

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2-Aminoimidazoles inhibitors of TGF-β receptor 1 von Bonafoux, Dominique, Chuaqui, Claudio, Boriack-Sjodin, P. Ann, Fitch, Chris, Hankins, Gretchen, Josiah, Serene, Black, Cheryl, Hetu, Gregg, Ling, Leona, Lee, Wen-Cherng

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Selective, Tight-Binding Inhibitors of Integrin α4β1 That Inhibit Allergic Airway Responses von Lin, Ko-chung, Ateeq, Humayun S, Hsiung, Sherry H, Chong, Lillian T, Zimmerman, Craig N, Castro, Alfredo, Lee, Wen-cherng, Hammond, Charles E, Kalkunte, Sandhya, Chen, Ling-Ling, Pepinsky, R. Blake, Leone, Diane R, Sprague, Andrew G, Abraham, William M, Gill, Alan, Lobb, Roy R, Adams, Steven P

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Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I) von Zhang, Lin, Fan, Junhua, Chong, Jer-Hong, Cesena, Angela, Tam, Betty Y.Y., Gilson, Charles, Boykin, Christina, Wang, Deping, Aivazian, Dikran, Marcotte, Doug, Xiao, Guangqing, Le Brazidec, Jean-Yves, Piao, Jinhua, Lundgren, Karen, Hong, Kevin, Vu, Khang, Nguyen, Khanh, Gan, Liang-Shang, Silvian, Laura, Ling, Leona, Teng, Min, Reff, Mitchell, Takeda, Nicole, Timple, Noel, Wang, Qin, Morena, Ron, Khan, Samina, Zhao, Shuo, Li, Tony, Lee, Wen-Cherng, Taveras, Arthur G., Chao, Jianhua

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