HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of no... von Serrano-Villar, Sergio, Sainz, Talia, Lee, Sulggi A, Hunt, Peter W, Sinclair, Elizabeth, Shacklett, Barbara L, Ferre, April L, Hayes, Timothy L, Somsouk, Ma, Hsue, Priscilla Y, Van Natta, Mark L, Meinert, Curtis L, Lederman, Michael M, Hatano, Hiroyu, Jain, Vivek, Huang, Yong, Hecht, Frederick M, Martin, Jeffrey N, McCune, Joseph M, Moreno, Santiago, Deeks, Steven G

Volltext

mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status von Neidleman, Jason, Luo, Xiaoyu, McGregor, Matthew, Xie, Guorui, Murray, Victoria, Greene, Warner C, Lee, Sulggi A, Roan, Nadia R

Volltext

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study von Elliott, Julian H, MBBS, McMahon, James H, MBBS, Chang, Christina C, MBBS, Lee, Sulggi A, MD, Hartogensis, Wendy, PhD, Bumpus, Namandje, PhD, Savic, Rada, PhD, Roney, Janine, MPH, Hoh, Rebecca, BA, Solomon, Ajantha, BSc, Piatak, Michael, PhD, Gorelick, Robert J, PhD, Lifson, Jeff, PhD, Bacchetti, Peter, Prof, Deeks, Steven G, Prof, Lewin, Sharon R, Prof

Volltext

Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging von Lee, Sulggi A, Sinclair, Elizabeth, Hatano, Hiroyu, Hsue, Priscilla Y, Epling, Lorrie, Hecht, Frederick M, Bangsberg, David R, Martin, Jeffrey N, McCune, Joseph M, Deeks, Steven G, Hunt, Peter W

Volltext

Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease von Barbehenn, Alton, Shi, Lei, Shao, Junzhe, Hoh, Rebecca, Hartig, Heather M., Pae, Vivian, Sarvadhavabhatla, Sannidhi, Donaire, Sophia, Sheikhzadeh, Caroline, Milush, Jeffrey, Laird, Gregory M., Mathias, Mignot, Ritter, Kristen, Peluso, Michael J., Martin, Jeffrey, Hecht, Frederick, Pilcher, Christopher, Cohen, Stephanie E., Buchbinder, Susan, Havlir, Diane, Gandhi, Monica, Henrich, Timothy J., Hatano, Hiroyu, Wang, Jingshen, Deeks, Steven G., Lee, Sulggi A.

Volltext

Assessing the associations between known genetic variants and substance use in people with HIV in the United States von Haas, Cameron B, Jordahl, Kristina M, Nance, Robin M, Whitney, Bridget M, Wang, Lu, Delaney, Joseph A C, Ruderman, Stephanie, Jia, Tongqiu, Mathews, Wm Christopher, Saag, Michael S, Lee, Sulggi A, Napravnik, Sonia, Jacobson, Jeffrey M, Chander, Geetanjali, McCall, Elizabeth M, Moore, Richard D, Mayer, Kenneth H, Mukherjee, Shubhabrata, Lee, Won Jun, Crane, Paul K, Crane, Heidi, Peter, Inga, Lindström, Sara

Volltext

No detectable alloreactive transcriptional responses under standard sample preparation conditions during donor-multiplexed single-cell RNA sequencing of peripheral blood mononuclea... von McGinnis, Christopher S, Siegel, David A, Xie, Guorui, Hartoularos, George, Stone, Mars, Ye, Chun J, Gartner, Zev J, Roan, Nadia R, Lee, Sulggi A

Volltext

A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size von Dwivedi, Ashok K, Gornalusse, Germán G, Siegel, David A, Barbehenn, Alton, Thanh, Cassandra, Hoh, Rebecca, Hobbs, Kristen S, Pan, Tony, Gibson, Erica A, Martin, Jeffrey, Hecht, Frederick, Pilcher, Christopher, Milush, Jeffrey, Busch, Michael P, Stone, Mars, Huang, Meei-Li, Reppetti, Julieta, Vo, Phuong M, Levy, Claire N, Roychoudhury, Pavitra, Jerome, Keith R, Hladik, Florian, Henrich, Timothy J, Deeks, Steven G, Lee, Sulggi A

Volltext

Immunologic Biomarkers, Morbidity, and Mortality in Treated HIV Infection von Hunt, Peter W., Lee, Sulggi A., Siedner, Mark J.

Volltext

Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals von George, Ashley F, Luo, Xiaoyu, Neidleman, Jason, Hoh, Rebecca, Vohra, Poonam, Thomas, Reuben, Shin, Min-Gyoung, Lee, Madeline J, Blish, Catherine A, Deeks, Steven G, Greene, Warner C, Lee, Sulggi A, Roan, Nadia R

Volltext

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy von Lee, Sulggi A, Bacchetti, Peter, Chomont, Nicolas, Fromentin, Remi, Lewin, Sharon R, O'Doherty, Una, Palmer, Sarah, Richman, Douglas D, Siliciano, Janet D, Yukl, Steven A, Deeks, Steven G, Burbelo, Peter D

Volltext

The Benefits of Early Antiretroviral Therapy for HIV Infection: How Early is Early Enough? von Lee, Sulggi A., Deeks, Steven G.

Volltext

Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2 von Yin, Kailin, Peluso, Michael J., Luo, Xiaoyu, Thomas, Reuben, Shin, Min-Gyoung, Neidleman, Jason, Andrew, Alicer, Young, Kyrlia C., Ma, Tongcui, Hoh, Rebecca, Anglin, Khamal, Huang, Beatrice, Argueta, Urania, Lopez, Monica, Valdivieso, Daisy, Asare, Kofi, Deveau, Tyler-Marie, Munter, Sadie E., Ibrahim, Rania, Ständker, Ludger, Lu, Scott, Goldberg, Sarah A., Lee, Sulggi A., Lynch, Kara L., Kelly, J. Daniel, Martin, Jeffrey N., Münch, Jan, Deeks, Steven G., Henrich, Timothy J., Roan, Nadia R.

Volltext

Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19 von Neidleman, Jason, Luo, Xiaoyu, George, Ashley F., McGregor, Matthew, Yang, Junkai, Yun, Cassandra, Murray, Victoria, Gill, Gurjot, Greene, Warner C., Vasquez, Joshua, Lee, Sulggi A., Ghosn, Eliver, Lynch, Kara L., Roan, Nadia R.

Volltext

CD8 T-Cell Expansion and Inflammation Linked to CMV Coinfection in ART-treated HIV Infection von Freeman, Michael L., Mudd, Joseph C., Shive, Carey L., Younes, Souheil-Antoine, Panigrahi, Soumya, Sieg, Scott F., Lee, Sulggi A., Hunt, Peter W., Calabrese, Leonard H., Gianella, Sara, Rodriguez, Benigno, Lederman, Michael M.

Volltext

Autologous neutralizing antibody responses after antiretroviral therapy in acute and early HIV-1 von Whitehill, Gregory D, Joy, Jaimy, Marino, Francesco E, Krause, Ryan, Mallick, Suvadip, Courtney, Hunter, Park, Kyewon, Carey, John, Hoh, Rebecca, Hartig, Heather, Pae, Vivian, Sarvadhavabhatla, Sannidhi, Donaire, Sophia, Deeks, Steven G, Lynch, Rebecca M, Lee, Sulggi A, Bar, Katharine J

Volltext

IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection von Younes, Souheil-Antoine, Freeman, Michael L, Mudd, Joseph C, Shive, Carey L, Reynaldi, Arnold, Panigrahi, Soumya, Estes, Jacob D, Deleage, Claire, Lucero, Carissa, Anderson, Jodi, Schacker, Timothy W, Davenport, Miles P, McCune, Joseph M, Hunt, Peter W, Lee, Sulggi A, Serrano-Villar, Sergio, Debernardo, Robert L, Jacobson, Jeffrey M, Canaday, David H, Sekaly, Rafick-Pierre, Rodriguez, Benigno, Sieg, Scott F, Lederman, Michael M

Volltext

Protracted yet Coordinated Differentiation of Long-Lived SARS-CoV-2-Specific CD8 + T Cells during Convalescence von Ma, Tongcui, Ryu, Heeju, McGregor, Matthew, Babcock, Benjamin, Neidleman, Jason, Xie, Guorui, George, Ashley F, Frouard, Julie, Murray, Victoria, Gill, Gurjot, Ghosn, Eliver, Newell, Evan W, Lee, Sulggi A, Roan, Nadia R

Volltext

Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV‐1 Transcription in a Phase IIb Trial von Lee, Sulggi A., Elliott, Julian H., McMahon, James, Hartogenesis, Wendy, Bumpus, Namandje N., Lifson, Jeffrey D., Gorelick, Robert J., Bacchetti, Peter, Deeks, Steven G., Lewin, Sharon R., Savic, Radojka M.

Volltext

Antiretroviral Therapy Concentrations Differ in Gut vs. Lymph Node Tissues and Are Associated With HIV Viral Transcription by a Novel RT-ddPCR Assay von Lee, Sulggi A., Telwatte, Sushama, Hatano, Hiroyu, Kashuba, Angela D.M., Cottrell, Mackenzie L., Hoh, Rebecca, Liegler, Teri J., Stephenson, Sophie, Somsouk, Ma, Hunt, Peter W., Deeks, Steven G., Yukl, Steven, Savic, Radojka M.

Volltext