On the Hospital Volume and Outcome Relationship: Does Specialization Matter More Than Volume? von Lee, Kris C. L., Sethuraman, Kannan, Yong, Jongsay

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Antiemetics: ASCO Guideline Update von Hesketh, Paul J, Kris, Mark G, Basch, Ethan, Bohlke, Kari, Barbour, Sally Y, Clark-Snow, Rebecca Anne, Danso, Michael A, Dennis, Kristopher, Dupuis, L Lee, Dusetzina, Stacie B, Eng, Cathy, Feyer, Petra C, Jordan, Karin, Noonan, Kimberly, Sparacio, Dee, Lyman, Gary H

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Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update von Hesketh, Paul J, Kris, Mark G, Basch, Ethan, Bohlke, Kari, Barbour, Sally Y, Clark-Snow, Rebecca Anne, Danso, Michael A, Dennis, Kristopher, Dupuis, L Lee, Dusetzina, Stacie B, Eng, Cathy, Feyer, Petra C, Jordan, Karin, Noonan, Kimberly, Sparacio, Dee, Somerfield, Mark R, Lyman, Gary H

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Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis von Sanyal, Arun J, Chalasani, Naga, Kowdley, Kris V, McCullough, Arthur, Diehl, Anna Mae, Bass, Nathan M, Neuschwander-Tetri, Brent A, Lavine, Joel E, Tonascia, James, Unalp, Aynur, Van Natta, Mark, Clark, Jeanne, Brunt, Elizabeth M, Kleiner, David E, Hoofnagle, Jay H, Robuck, Patricia R

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Cluster-Randomized, Crossover Trial of Head Positioning in Acute Stroke von Anderson, Craig S, Arima, Hisatomi, Lavados, Pablo, Billot, Laurent, Hackett, Maree L, Olavarría, Verónica V, Muñoz Venturelli, Paula, Brunser, Alejandro, Peng, Bin, Cui, Liying, Song, Lily, Rogers, Kris, Middleton, Sandy, Lim, Joyce Y, Forshaw, Denise, Lightbody, C. Elizabeth, Woodward, Mark, Pontes-Neto, Octavio, De Silva, H. Asita, Lin, Ruey-Tay, Lee, Tsong-Hai, Pandian, Jeyaraj D, Mead, Gillian E, Robinson, Thompson, Watkins, Caroline

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Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial von Neuschwander-Tetri, Brent A, Prof, Loomba, Rohit, MD, Sanyal, Arun J, Prof, Lavine, Joel E, Prof, Van Natta, Mark L, MHS, Abdelmalek, Manal F, MD, Chalasani, Naga, Prof, Dasarathy, Srinivasan, MD, Diehl, Anna Mae, Prof, Hameed, Bilal, MD, Kowdley, Kris V, Prof, McCullough, Arthur, Prof, Terrault, Norah, Prof, Clark, Jeanne M, Prof, Tonascia, James, Prof, Brunt, Elizabeth M, Prof, Kleiner, David E, MD, Doo, Edward, MD

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Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis von Vujkovic, Marijana, Keaton, Jacob M., Lynch, Julie A., Miller, Donald R., Zhou, Jin, Tcheandjieu, Catherine, Huffman, Jennifer E., Assimes, Themistocles L., Lorenz, Kimberly, Zhu, Xiang, Hilliard, Austin T., Judy, Renae L., Huang, Jie, Lee, Kyung M., Klarin, Derek, Pyarajan, Saiju, Danesh, John, Melander, Olle, Rasheed, Asif, Mallick, Nadeem H., Hameed, Shahid, Qureshi, Irshad H., Afzal, Muhammad Naeem, Malik, Uzma, Jalal, Anjum, Abbas, Shahid, Sheng, Xin, Gao, Long, Kaestner, Klaus H., Susztak, Katalin, Sun, Yan V., DuVall, Scott L., Cho, Kelly, Lee, Jennifer S., Gaziano, J. Michael, Phillips, Lawrence S., Meigs, James B., Reaven, Peter D., Wilson, Peter W., Edwards, Todd L., Rader, Daniel J., Damrauer, Scott M., O’Donnell, Christopher J., Tsao, Philip S., Chang, Kyong-Mi, Voight, Benjamin F., Saleheen, Danish

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SARS-CoV-2 infection of the oral cavity and saliva von Huang, Ni, Pérez, Paola, Kato, Takafumi, Mikami, Yu, Okuda, Kenichi, Gilmore, Rodney C., Conde, Cecilia Domínguez, Gasmi, Billel, Stein, Sydney, Beach, Margaret, Pelayo, Eileen, Maldonado, Jose O., Lafont, Bernard A., Jang, Shyh-Ing, Nasir, Nadia, Padilla, Ricardo J., Murrah, Valerie A., Maile, Robert, Lovell, William, Wallet, Shannon M., Bowman, Natalie M., Meinig, Suzanne L., Wolfgang, Matthew C., Choudhury, Saibyasachi N., Novotny, Mark, Aevermann, Brian D., Scheuermann, Richard H., Cannon, Gabrielle, Anderson, Carlton W., Lee, Rhianna E., Marchesan, Julie T., Bush, Mandy, Freire, Marcelo, Kimple, Adam J., Herr, Daniel L., Rabin, Joseph, Grazioli, Alison, Das, Sanchita, French, Benjamin N., Pranzatelli, Thomas, Chiorini, John A., Kleiner, David E., Pittaluga, Stefania, Hewitt, Stephen M., Burbelo, Peter D., Chertow, Daniel, Frank, Karen, Lee, Janice, Boucher, Richard C., Teichmann, Sarah A., Warner, Blake M., Byrd, Kevin M.

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Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes von Naidoo, Jarushka, Santos-Zabala, Maria L, Iyriboz, Tunc, Woo, Kaitlin M, Sima, Camelia S, Fiore, John J, Kris, Mark G, Riely, Gregory J, Lito, Piro, Iqbal, Afsheen, Veach, Stephen, Smith-Marrone, Stephanie, Sarkaria, Inderpal S, Krug, Lee M, Rudin, Charles M, Travis, William D, Rekhtman, Natasha, Pietanza, Maria C

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International scientists formulate a roadmap for insect conservation and recovery von Harvey, Jeffrey A., Heinen, Robin, Armbrecht, Inge, Basset, Yves, Baxter-Gilbert, James H., Bezemer, T. Martijn, Böhm, Monika, Bommarco, Riccardo, Borges, Paulo A. V., Cardoso, Pedro, Clausnitzer, Viola, Cornelisse, Tara, Crone, Elizabeth E., Dicke, Marcel, Dijkstra, Klaas-Douwe B., Dyer, Lee, Ellers, Jacintha, Fartmann, Thomas, Forister, Mathew L., Furlong, Michael J., Garcia-Aguayo, Andres, Gerlach, Justin, Gols, Rieta, Goulson, Dave, Habel, Jan-Christian, Haddad, Nick M., Hallmann, Caspar A., Henriques, Sérgio, Herberstein, Marie E., Hochkirch, Axel, Hughes, Alice C., Jepsen, Sarina, Jones, T. Hefin, Kaydan, Bora M., Kleijn, David, Klein, Alexandra-Maria, Latty, Tanya, Leather, Simon R., Lewis, Sara M., Lister, Bradford C., Losey, John E., Lowe, Elizabeth C., Macadam, Craig R., Montoya-Lerma, James, Nagano, Christopher D., Ogan, Sophie, Orr, Michael C., Painting, Christina J., Pham, Thai-Hong, Potts, Simon G., Rauf, Aunu, Roslin, Tomas L., Samways, Michael J., Sanchez-Bayo, Francisco, Sar, Sim A., Schultz, Cheryl B., Soares, António O., Thancharoen, Anchana, Tscharntke, Teja, Tylianakis, Jason M., Umbers, Kate D. L., Vet, Louise E. M., Visser, Marcel E., Vujic, Ante, Wagner, David L., WallisDeVries, Michiel F., Westphal, Catrin, White, Thomas E., Wilkins, Vicky L., Williams, Paul H., Wyckhuys, Kris A. G., Zhu, Zeng-Rong, de Kroon, Hans

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A randomized phase 2b study of peginterferon lambda-1a for the treatment of chronic HCV infection von Muir, Andrew J, Arora, Sanjeev, Everson, Gregory, Flisiak, Robert, George, Jacob, Ghalib, Reem, Gordon, Stuart C, Gray, Todd, Greenbloom, Susan, Hassanein, Tarek, Hillson, Jan, Horga, Maria Arantxa, Jacobson, Ira M, Jeffers, Lennox, Kowdley, Kris V, Lawitz, Eric, Lueth, Stefan, Rodriguez-Torres, Maribel, Rustgi, Vinod, Shemanski, Lynn, Shiffman, Mitchell L, Srinivasan, Subasree, Vargas, Hugo E, Vierling, John M, Xu, Dong, Lopez-Talavera, Juan C, Zeuzem, Stefan

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Four distinct trajectories of tau deposition identified in Alzheimer’s disease von Vogel, Jacob W., Young, Alexandra L., Oxtoby, Neil P., Smith, Ruben, Ossenkoppele, Rik, Strandberg, Olof T., La Joie, Renaud, Aksman, Leon M., Grothe, Michel J., Iturria-Medina, Yasser, Pontecorvo, Michael J., Devous, Michael D., Rabinovici, Gil D., Alexander, Daniel C., Lyoo, Chul Hyoung, Evans, Alan C., Hansson, Oskar

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Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I von Verstovsek, Srdan, Mesa, Ruben A, Gotlib, Jason, Levy, Richard S, Gupta, Vikas, DiPersio, John F, Catalano, John V, Deininger, Michael W N, Miller, Carole B, Silver, Richard T, Talpaz, Moshe, Winton, Elliott F, Harvey, Jr, Jimmie H, Arcasoy, Murat O, Hexner, Elizabeth O, Lyons, Roger M, Raza, Azra, Vaddi, Kris, Sun, William, Peng, Wei, Sandor, Victor, Kantarjian, Hagop

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The 2021 report of the Lancet Countdown on health and climate change: code red for a healthy future von Romanello, Marina, McGushin, Alice, Di Napoli, Claudia, Drummond, Paul, Hughes, Nick, Jamart, Louis, Kennard, Harry, Lampard, Pete, Solano Rodriguez, Baltazar, Arnell, Nigel, Ayeb-Karlsson, Sonja, Belesova, Kristine, Cai, Wenjia, Campbell-Lendrum, Diarmid, Capstick, Stuart, Chambers, Jonathan, Chu, Lingzhi, Ciampi, Luisa, Dalin, Carole, Dasandi, Niheer, Dasgupta, Shouro, Davies, Michael, Dominguez-Salas, Paula, Dubrow, Robert, Ebi, Kristie L, Eckelman, Matthew, Ekins, Paul, Escobar, Luis E, Georgeson, Lucien, Grace, Delia, Graham, Hilary, Gunther, Samuel H, Hartinger, Stella, He, Kehan, Heaviside, Clare, Hess, Jeremy, Hsu, Shih-Che, Jankin, Slava, Jimenez, Marcia P, Kelman, Ilan, Kiesewetter, Gregor, Kinney, Patrick L, Kjellstrom, Tord, Kniveton, Dominic, Lee, Jason K W, Lemke, Bruno, Liu, Yang, Liu, Zhao, Lott, Melissa, Lowe, Rachel, Martinez-Urtaza, Jaime, Maslin, Mark, McAllister, Lucy, McMichael, Celia, Mi, Zhifu, Milner, James, Minor, Kelton, Mohajeri, Nahid, Moradi-Lakeh, Maziar, Morrissey, Karyn, Munzert, Simon, Murray, Kris A, Neville, Tara, Nilsson, Maria, Obradovich, Nick, Sewe, Maquins Odhiambo, Oreszczyn, Tadj, Otto, Matthias, Owfi, Fereidoon, Pearman, Olivia, Pencheon, David, Rabbaniha, Mahnaz, Robinson, Elizabeth, Rocklöv, Joacim, Salas, Renee N, Semenza, Jan C, Sherman, Jodi, Shi, Liuhua, Springmann, Marco, Tabatabaei, Meisam, Taylor, Jonathon, Trinanes, Joaquin, Shumake-Guillemot, Joy, Vu, Bryan, Wagner, Fabian, Wilkinson, Paul, Winning, Matthew, Yglesias, Marisol, Zhang, Shihui, Gong, Peng, Montgomery, Hugh, Costello, Anthony, Hamilton, Ian

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Hepatitis B Virus–Specific and Global T-Cell Dysfunction in Chronic Hepatitis B von Park, Jang-June, Wong, David K, Wahed, Abdus S, Lee, William M, Feld, Jordan J, Terrault, Norah, Khalili, Mandana, Sterling, Richard K, Kowdley, Kris V, Bzowej, Natalie, Lau, Daryl T, Kim, W. Ray, Smith, Coleman, Carithers, Robert L, Torrey, Keith W, Keith, James W, Levine, Danielle L, Traum, Daniel, Ho, Suzanne, Valiga, Mary E, Johnson, Geoffrey S, Doo, Edward, Lok, Anna S.F, Chang, Kyong-Mi

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Bronchioloalveolar Pathologic Subtype and Smoking History Predict Sensitivity to Gefitinib in Advanced Non–Small-Cell Lung Cancer von MILLER, Vincent A, KRIS, Mark G, TYSON, Leslie, VENKATRAMAN, Ennapadam, BEN-PORAT, Leah, MEMOLI, Natalie, ZAKOWSKI, Maureen, RUSCH, Valerie, HEELAN, Robert T, SHAH, Neelam, PATEL, Jyoti, AZZOLI, Christopher, GOMEZ, Jorge, KRUG, Lee M, PAO, William, RIZVI, Naiyer, PIZZO, Barbara

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Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease von Vogel, Jacob W., Iturria-Medina, Yasser, Strandberg, Olof T., Smith, Ruben, Levitis, Elizabeth, Evans, Alan C., Hansson, Oskar

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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers von Ozkan-Dagliyan, Irem, Diehl, J. Nathaniel, George, Samuel D., Schaefer, Antje, Papke, Bjoern, Klotz-Noack, Kathleen, Waters, Andrew M., Goodwin, Craig M., Gautam, Prson, Pierobon, Mariaelena, Peng, Sen, Gilbert, Thomas S.K., Lin, Kevin H., Dagliyan, Onur, Wennerberg, Krister, Petricoin, Emanuel F., Tran, Nhan L., Bhagwat, Shripad V., Tiu, Ramon V., Peng, Sheng-Bin, Herring, Laura E., Graves, Lee M., Sers, Christine, Wood, Kris C., Cox, Adrienne D., Der, Channing J.

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Quantifying intra-tumoral genetic heterogeneity of glioblastoma toward precision medicine using MRI and a data-inclusive machine learning algorithm von Wang, Lujia, Wang, Hairong, D'Angelo, Fulvio, Curtin, Lee, Sereduk, Christopher P, Leon, Gustavo De, Singleton, Kyle W, Urcuyo, Javier, Hawkins-Daarud, Andrea, Jackson, Pamela R, Krishna, Chandan, Zimmerman, Richard S, Patra, Devi P, Bendok, Bernard R, Smith, Kris A, Nakaji, Peter, Donev, Kliment, Baxter, Leslie C, Mrugała, Maciej M, Ceccarelli, Michele, Iavarone, Antonio, Swanson, Kristin R, Tran, Nhan L, Hu, Leland S, Li, Jing

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Structure, function and diversity of the healthy human microbiome von Huttenhower, Curtis, Gevers, Dirk, Knight, Rob, Abubucker, Sahar, Badger, Jonathan H, Chinwalla, Asif T, Creasy, Heather H, Earl, Ashlee M, FitzGerald, Michael G, Fulton, Robert S, Giglio, Michelle G, Hallsworth-Pepin, Kymberlie, Lobos, Elizabeth A, Madupu, Ramana, Magrini, Vincent, Martin, John C, Mitreva, Makedonka, Muzny, Donna M, Sodergren, Erica J, Versalovic, James, Wollam, Aye M, Worley, Kim C, Wortman, Jennifer R, Young, Sarah K, Zeng, Qiandong, Aagaard, Kjersti M, Abolude, Olukemi O, Allen-Vercoe, Emma, Alm, Eric J, Alvarado, Lucia, Andersen, Gary L, Anderson, Scott, Appelbaum, Elizabeth, Arachchi, Harindra M, Armitage, Gary, Arze, Cesar A, Ayvaz, Tulin, Baker, Carl C, Begg, Lisa, Belachew, Tsegahiwot, Bhonagiri, Veena, Bihan, Monika, Blaser, Martin J, Bloom, Toby, Bonazzi, Vivien, Paul Brooks, J, Buck, Gregory A, Buhay, Christian J, Busam, Dana A, Campbell, Joseph L, et. al

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