Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities von Coppé, Jean-Philippe, Mori, Miki, Pan, Bo, Yau, Christina, Wolf, Denise M., Ruiz-Saenz, Ana, Brunen, Diede, Prahallad, Anirudh, Cornelissen-Steijger, Paulien, Kemper, Kristel, Posch, Christian, Wang, Changjun, Dreyer, Courtney A., Krijgsman, Oscar, Lee, Pei Rong Evelyn, Chen, Zhongzhong, Peeper, Daniel S., Moasser, Mark M., Bernards, René, van ‘t Veer, Laura J.

Volltext

Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors von Bartelink, Imke H, Prideaux, Brendan, Krings, Gregor, Wilmes, Lisa, Lee, Pei Rong Evelyn, Bo, Pan, Hann, Byron, Coppé, Jean-Philippe, Heditsian, Diane, Swigart-Brown, Lamorna, Jones, Ella F, Magnitsky, Sergey, Keizer, Ron J, de Vries, Niels, Rosing, Hilde, Pawlowska, Nela, Thomas, Scott, Dhawan, Mallika, Aggarwal, Rahul, Munster, Pamela N, Esserman, Laura J, Ruan, Weiming, Wu, Alan H B, Yee, Douglas, Dartois, Véronique, Savic, Radojka M, Wolf, Denise M, van 't Veer, Laura

Volltext

Does the combination of optimal substitutions at the C²-, N⁵- and N⁸-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A₃ adenosine... von Cheong, Siew Lee, Dolzhenko, Anton V, Paoletta, Silvia, Lee, Evelyn Pei Rong, Kachler, Sonja, Federico, Stephanie, Klotz, Karl-Norbert, Dolzhenko, Anna V, Spalluto, Giampiero, Moro, Stefano, Pastorin, Giorgia

Volltext

Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies von Wolf, Denise M., Yau, Christina, Wulfkuhle, Julia, Brown-Swigart, Lamorna, Gallagher, Rosa I., Lee, Pei Rong Evelyn, Zhu, Zelos, Magbanua, Mark J., Sayaman, Rosalyn, O’Grady, Nicholas, Basu, Amrita, Delson, Amy, Coppé, Jean Philippe, Lu, Ruixiao, Braun, Jerome, Asare, Smita M., Sit, Laura, Matthews, Jeffrey B., Perlmutter, Jane, Hylton, Nola, Liu, Minetta C., Pohlmann, Paula, Symmans, W. Fraser, Rugo, Hope S., Isaacs, Claudine, DeMichele, Angela M., Yee, Douglas, Berry, Donald A., Pusztai, Lajos, Petricoin, Emanuel F., Hirst, Gillian L., Esserman, Laura J., van 't Veer, Laura J.

Volltext

Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle von Bartelink, Imke H., Jones, Ella F., Shahidi‐Latham, Sheerin K., Lee, Pei Rong Evelyn, Zheng, Yanan, Vicini, Paolo, ‘t Veer, Laura, Wolf, Denise, Iagaru, Andrei, Kroetz, Deanna L., Prideaux, Brendan, Cilliers, Cornelius, Thurber, Greg M., Wimana, Zena, Gebhart, Geraldine

Volltext

Abstract 2612: BluePrint Luminal subtype predicts non-response to HER2-targeted therapies in HR+/HER2+ I-SPY 2 breast cancer patients von Lee, Pei Rong Evelyn, Zhu, Zelos, Wolf, Denise, Yau, Christina, Audeh, William, Glas, Annuska, Brown-Swigart, Lamorna, Hirst, Gillian, DeMichele, Angela, Investigators, I-SPY 2 TRIAL, Esserman, Laura, Veer, Laura van 't

Volltext

Abstract 956: Systematic identification of the actionable kinase dependencies of chemotherapy-resistant triple-negative breast cancer von Coppe, Jean-Philippe F., Bo, Pan, Borden, Carolien van der, Koemans, Nina, Wang, Changjun, Wolf, Denise, Yau, Christina, Bakker, Sietske, Hartog, Marij, Mori, Miki, Ruiz-Saenz, Ana, Chen, Zhongzhong, Olow, Aleksandra, Lee, Pei Rong Evelyn, Veer, Laura van 't

Volltext

An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer von Olow, Aleksandra, Chen, Zhongzhong, Niedner, R Hannes, Wolf, Denise M, Yau, Christina, Pankov, Aleksandr, Lee, Evelyn Pei Rong, Brown-Swigart, Lamorna, van 't Veer, Laura J, Coppé, Jean-Philippe

Volltext

Abstract P2-05-09: Functional mapping of the oncogenic kinome activity of triple-negative breast cancer cells von Pan, Bo, Mori, Miki, Lee, Pei Rong Evelyn, Hartog, Marij, Sun, Qiang, van 't Veer, Laura, Coppe, Jean-Philippe

Volltext

Spatial distribution of veliparib measured by matrix-assisted laser desorption ionization mass spectrometry in triple-negative breast cancer tumors von Bartelink, Imke Heleen, Prideaux, Brendan, Hann, Byron, Krings, Gregor, Coppe, Jean-Philippe, Brown Swigart, Lamorna, Lee, Evelyn Pei Rong, Esserman, Laura, Yee, Douglas, Wolf, Denise, Savic, Rada M.

Volltext

Abstract P6-11-02: Spatial distribution of veliparib measured by matrix assisted laser desorption ionization mass spectrometry in triple negative breast cancer tumors von Bartelink, Imke H, Prideaux, Brendan, Hann, Byron, Krings, Gregor, Coppe, Jean-Phillippe, Swigart-Brown, Lamorna, Lee, Pei Rong Evelyn, Esserman, Laura, Yee, Douglas, Wolf, Denise, Savic, Rada M, van t Veer, Laura

Volltext

Does the combination of optimal substitutions at the C super(2-, N) super(5)- and N super(8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of... von Cheong, Siew Lee, Dolzhenko, Anton V, Paoletta, Silvia, Lee, Evelyn Pei Rong, Kachler, Sonja, Federico, Stephanie, Klotz, Karl-Norbert, Dolzhenko, Anna V, Spalluto, Giampiero, Moro, Stefano, Pastorin, Giorgia

Volltext

Does the combination of optimal substitutions at the C 2-, N 5- and N 8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A 3 adeno... von Cheong, Siew Lee, Dolzhenko, Anton V., Paoletta, Silvia, Lee, Evelyn Pei Rong, Kachler, Sonja, Federico, Stephanie, Klotz, Karl-Norbert, Dolzhenko, Anna V., Spalluto, Giampiero, Moro, Stefano, Pastorin, Giorgia

Volltext