Selective BTK inhibition improves bendamustine therapy response and normalizes immune effector functions in chronic lymphocytic leukemia von Lee‐Vergés, Eriong, Hanna, Bola S., Yazdanparast, Haniyeh, Rodríguez, Vanina, Rodríguez, Marta Leonor, Giró, Ariadna, Vidal‐Crespo, Anna, Rosich, Laia, Amador, Virginia, Aymerich, Marta, Villamor, Neus, Delgado, Julio, Lichter, Peter, Pérez‐Galán, Patricia, López‐Guerra, Mònica, Campo, Elías, Seiffert, Martina, Colomer, Dolors

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Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells von López-Guerra, Mónica, Xargay-Torrent, Sílvia, Fuentes, Patricia, Roldán, Jocabed, González-Farré, Blanca, Rosich, Laia, Silkenstedt, Elisabeth, García-León, María J., Lee-Vergés, Eriong, Giménez, Neus, Giró, Ariadna, Aymerich, Marta, Villamor, Neus, Delgado, Julio, López-Guillermo, Armando, Puente, Xose S., Campo, Elias, Toribio, María L., Colomer, Dolors

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The Bruton tyrosine kinase inhibitor CC-292 shows activity in mantle cell lymphoma and synergizes with lenalidomide and NIK inhibitors depending on nuclear factor-κB mutational sta... von Vidal-Crespo, Anna, Rodriguez, Vanina, Matas-Cespedes, Alba, Lee, Eriong, Rivas-Delgado, Alfredo, Giné, Eva, Navarro, Alba, Beà, Sílvia, Campo, Elias, López-Guillermo, Armando, Lopez-Guerra, Monica, Roué, Gaël, Colomer, Dolors, Pérez-Galán, Patricia

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Genomic complexity and IGHV mutational status are key predictors of outcome of chronic lymphocytic leukemia patients with TP53 disruption von Delgado, Julio, Salaverria, Itziar, Baumann, Tycho, Martínez-Trillos, Alejandra, Lee, Eriong, Jiménez, Laura, Navarro, Alba, Royo, Cristina, Santacruz, Rodrigo, López, Cristina, Payer, Angel R, Colado, Enrique, González, Marcos, Armengol, Lluís, Colomer, Dolors, Pinyol, Magda, Villamor, Neus, Aymerich, Marta, Carrió, Ana, Costa, Dolors, Clot, Guillem, Giné, Eva, López-Guillermo, Armando, Campo, Elías, Beà, Sílvia

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CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia von Montraveta, Arnau, Lee-Vergés, Eriong, Roldán, Jocabed, Jiménez, Laura, Cabezas, Sandra, Clot, Guillem, Pinyol, Magda, Xargay-Torrent, Sílvia, Rosich, Laia, Arimany-Nardí, Cristina, Aymerich, Marta, Villamor, Neus, López-Guillermo, Armando, Pérez-Galán, Patricia, Roué, Gaël, Pastor-Anglada, Marçal, Campo, Elías, López-Guerra, Mónica, Colomer, Dolors

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Bcl-2high mantle cell lymphoma cells are sensitized to acadesine with ABT-199 von Montraveta, Arnau, Xargay-Torrent, Sílvia, Rosich, Laia, López-Guerra, Mònica, Roldán, Jocabed, Rodríguez, Vanina, Lee-Vergés, Eriong, de Frías, Mercè, Campàs, Clara, Campo, Elias, Roué, Gaël, Colomer, Dolors

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Genomic complexity and IGHV mutational status are key predictors of outcome of chronic lymphocytic leukemia patients with TP53 disruption von Delgado, Julio (Delgado González), Salaverria Frigola, Itziar, Baumann, Tycho, Martínez Trillos, Alejandra, Lee, Eriong, Jiménez, Laura, Navarro López, Alba, Royo Moreno, Cristina, Santacruz, Rodrigo, López, Cristina, Payer, Ángel R, Colado, Enrique, González, Marcos, Armengol, Lluís, Colomer Pujol, Dolors, Pinyol, Magda, Villamor i Casas, Neus, Aymerich Gregorio, Marta, Carrió, Ana, Costa, Dolors, Clot, Guillem, Giné Soca, Eva, López Guillermo, Armando, Campo Güerri, Elias, Beà Bobet, Sílvia M

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Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells von López-Guerra, Mónica, Xargay i Torrent, Sílvia, Fuentes, Patricia, Roldán, Jocabed, González Farré, Blanca, Rosich, Laia, Silkenstedt, Elisabeth, García León, María J, Lee-Vergés, Eriong, Giménez Carabaza, Neus, Giró, Ariadna, Aymerich Gregorio, Marta, Villamor i Casas, Neus, Delgado, Julio (Delgado González), López Guillermo, Armando, Puente, Xose S, Campo Güerri, Elias, Toribio, María L, Colomer Pujol, Dolors

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The BET Inhibitor GS-626510 Converges with Idelalisib through the Inhibition of Tumor-Macrophage Crosstalk and Cytokine Production in Diffuse Large B-Cell Lymphoma von Valero, Juan G, Chamorro-Jorganes, Aranzazu, Walker, Katie, Guerrero-Hernandez, Martina, Rodriguez, Vanina, Recasens-Zorzo, Clara, Esteve-Arenys, Anna, Lee-Verges, Eriong, Matas-Cespedes, Alba, Serrat, Neus, Colomer, Dolors, Lopez-Guillermo, Armando, Tannheimer, Stacey, Pérez-Galán, Patricia, Roue, Gael

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Detailed Molecular Analysis of Patients with Chronic Lymphocytic Leukemia Carrying 17p Deletions Reveals Concurrent Abnormalities with Prognostic Impact von Delgado, Julio, Salaverría, Itziar, Lee, Eriong, Jiménez, Laura, Navarro, Alba, Colomer, Dolors, Dlouhy, Ivan, Conde, Laura, Martinez-Trillos, Alejandra, Lopez, Cristina, Villamor, Neus, Aymerich, Marta, Rozman, María, Giné, Eva, Costa, Dolors, Carrió, Anna, López-Guillermo, Armando, Campo, Elías, Beà, Sílvia

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Abstract 885: Human organic cation transporter 1 (hOCT1) as a mediator of bendamustine cytotoxic action von Arimany-Nardi, Cristina, Montraveta, Arnau, Lee-Vergés, Eriong, Koepsell, Hermann, Colomer, Dolors, Pastor-Anglada, Marçal

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Bcl-2 high mantle cell lymphoma cells are sensitized to acadesine with ABT-199 von Montraveta, Arnau, Xargay-Torrent, Sílvia, Rosich, Laia, López-Guerra, Mònica, Roldán, Jocabed, Rodríguez, Vanina, Lee-Vergés, Eriong, de Frías, Mercè, Campàs, Clara, Campo, Elias, Roué, Gaël, Colomer, Dolors

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Abstract 993: Upregulation of B-cell activation genes and negative regulators of apoptosis determines resistance to bendamustine in chronic lymphocytic leukemia cells von Lee-Verges, Eriong, Montraveta, Arnau, Pinyol, Magda, Jares, Pedro, Arimany-Nardi, Cristina, Aymerich, Marta, Villamor, Neus, Pastor-Anglada, Marçal, Lopez-Guillermo, Armando, Perez-Galan, Patricia, Roue, Gael, Campo, Elias, Colomer, Dolors

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CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia von Montraveta, Arnau, Lee-Vergés, Eriong, Roldán, Jocabed, Jiménez, Laura, Cabezas, Sandra, Clot, Guillem, Pinyol, Magda, Xargay i Torrent, Sílvia, Rosich, Laia, Arimany Nardi, Cristina, Aymerich Gregorio, Marta, Villamor i Casas, Neus, López Guillermo, Armando, Pérez Galán, Patricia, Roué, Gaël, Pastor Anglada, Marçal, Campo Güerri, Elias, López-Guerra, Mónica, Colomer Pujol, Dolors

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Genomic complexity and IGHV mutational status are key predictors of outcome of chronic lymphocytic leukemia patients with TP53 disruption von Delgado, Julio (Delgado González), Salaverria Frigola, Itziar, Baumann, Tycho, Martínez Trillos, Alejandra, Lee, Eriong, Jiménez, Laura, Navarro López, Alba, Royo Moreno, Cristina, Santacruz, Rodrigo, López, Cristina, Payer, Ángel R, Colado, Enrique, González, Marcos, Armengol, Lluís, Colomer Pujol, Dolors, Pinyol, Magda, Villamor i Casas, Neus, Aymerich Gregorio, Marta, Carrió, Ana, Costa, Dolors, Clot, Guillem, Giné Soca, Eva, López Guillermo, Armando, Campo Güerri, Elias, Beà Bobet, Sílvia M

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