Calcium as a reliable marker for the quantitative assessment of endoplasmic reticulum stress in live cells von Lebeau, Paul F., Platko, Khrystyna, Byun, Jae Hyun, Austin, Richard C.

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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance von Lebeau, Paul F., Byun, Jae Hyun, Platko, Khrystyna, Saliba, Paul, Sguazzin, Matthew, MacDonald, Melissa E., Paré, Guillaume, Steinberg, Gregory R., Janssen, Luke J., Igdoura, Suleiman A., Tarnopolsky, Mark A., Wayne Chen, S. R., Seidah, Nabil G., Magolan, Jakob, Austin, Richard C.

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Repurposing Two Old Friends to Fight Cancer: Caffeine and Statins von Stouth, Derek W, Lebeau, Paul F, Austin, Richard C

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Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice von Lebeau, Paul F., Byun, Jae Hyun, Platko, Khrystyna, MacDonald, Melissa E., Poon, Samantha V., Faiyaz, Mahi, Seidah, Nabil G., Austin, Richard C.

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GDF10 is a negative regulator of vascular calcification von Platko, Khrystyna, Gyulay, Gabriel, Lebeau, Paul F., MacDonald, Melissa E., Lynn, Edward G., Byun, Jae Hyun, Igdoura, Suleiman A., Holden, Rachel M., Roubtsova, Anna, Seidah, Nabil G., Krepinsky, Joan C., Austin, Richard C.

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Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin von Susan-Resiga, Delia, Girard, Emmanuelle, Essalmani, Rachid, Roubtsova, Anna, Marcinkiewicz, Jadwiga, Derbali, Rabeb M., Evagelidis, Alexandra, Byun, Jae H., Lebeau, Paul F., Austin, Richard C., Seidah, Nabil G.

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A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice von Platko, Khrystyna, Lebeau, Paul F, Nederveen, Joshua P, Byun, Jae Hyun, MacDonald, Melissa E, Bourgeois, Jacqueline M, Tarnopolsky, Mark A, Austin, Richard C

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Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice von Lebeau, Paul F., Byun, Jae Hyun, Platko, Khrystyna, Al-Hashimi, Ali A., Lhoták, Šárka, MacDonald, Melissa E., Mejia-Benitez, Aurora, Prat, Annik, Igdoura, Suleiman A., Trigatti, Bernardo, Maclean, Kenneth N., Seidah, Nabil G., Austin, Richard C.

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The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases von Lebeau, Paul F, Platko, Khrystyna, Byun, Jae Hyun, Makda, Yumna, Austin, Richard C

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TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells von Platko, Khrystyna, Lebeau, Paul F., Gyulay, Gabriel, Lhoták, Šárka, MacDonald, Melissa E., Pacher, Giusepina, Hyun Byun, Jae, Boivin, Felix J., Igdoura, Suleiman A., Cutz, Jean-Claude, Bridgewater, Darren, Ingram, Alistair J., Krepinsky, Joan C., Austin, Richard C.

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Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism von Lebeau, Paul, Al-Hashimi, Ali, Sood, Sudesh, Lhoták, Šárka, Yu, Pei, Gyulay, Gabriel, Paré, Guillaume, Chen, S.R. Wayne, Trigatti, Bernardo, Prat, Annik, Seidah, Nabil G., Austin, Richard C.

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The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury von Lebeau, Paul F, Wassef, Hanny, Byun, Jae Hyun, Platko, Khrystyna, Ason, Brandon, Jackson, Simon, Dobroff, Joshua, Shetterly, Susan, Richards, William G, Al-Hashimi, Ali A, Won, Kevin Doyoon, Mbikay, Majambu, Prat, Annik, Tang, An, Paré, Guillaume, Pasqualini, Renata, Seidah, Nabil G, Arap, Wadih, Chrétien, Michel, Austin, Richard C

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The trypan blue cellular debris assay: a novel low-cost method for the rapid quantification of cell death von Lebeau, Paul F., Chen, Jack, Byun, Jae Hyun, Platko, Khrystyna, Austin, Richard C.

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GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury von Platko, Khrystyna, Lebeau, Paul F., Byun, Jae Hyun, Poon, Samantha V., Day, Emily A., MacDonald, Melissa E., Holzapfel, Nicholas, Mejia-Benitez, Aurora, Maclean, Kenneth N., Krepinsky, Joan C., Austin, Richard C.

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Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor von Al-Hashimi, Ali A., Lebeau, Paul, Majeed, Fadwa, Polena, Enio, Lhotak, Šárka, Collins, Celeste A.F., Pinthus, Jehonathan H., Gonzalez-Gronow, Mario, Hoogenes, Jen, Pizzo, Salvatore V., Crowther, Mark, Kapoor, Anil, Rak, Janusz, Gyulay, Gabriel, D’Angelo, Sara, Marchiò, Serena, Pasqualini, Renata, Arap, Wadih, Shayegan, Bobby, Austin, Richard C.

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Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity von Byun, Jae Hyun, Lebeau, Paul F, Platko, Khrystyna, Carlisle, Rachel E, Faiyaz, Mahi, Chen, Jack, MacDonald, Melissa E, Makda, Yumna, Yousof, Tamana, Lynn, Edward G, Dickhout, Jeffrey G, Krepinsky, Joan C, Weaver, Fiona, Igdoura, Suleiman A, Seidah, Nabil G, Austin, Richard C

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MAPping the kinase landscape of macrophage activation von Platko, Khrystyna, Lebeau, Paul, Austin, Richard C.

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Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death von Lebeau, Paul, Byun, Jae Hyun, Yousof, Tamana, Austin, Richard C.

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Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions von Crane, Elizabeth D., Al-Hashimi, Ali A., Chen, Jack, Lynn, Edward G., Won, Kevin Doyoon, Lhoták, Šárka, Naeim, Magda, Platko, Khrystyna, Lebeau, Paul, Byun, Jae Hyun, Shayegan, Bobby, Krepinsky, Joan C., Rayner, Katey J., Marchiò, Serena, Pasqualini, Renata, Arap, Wadih, Austin, Richard C.

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The loss-of-function PCSK9(Q152H) variant increases ER chaperones GRP78 and GRP94 and protects against liver injury von Lebeau, Paul F., Wassef, Hanny, Byun, Jae Hyun, Platko, Khrystyna, Ason, Brandon, Jackson, Simon, Dobroff, Joshua, Shetterly, Susan, Richards, William G., Al-Hashimi, Ali A., Won, Kevin Doyoon, Mbikay, Majambu, Prat, Annik, Tang, An, Pare, Guillaume, Pasqualini, Renata, Seidah, Nabil G., Arap, Wadih, Chretien, Michel, Austin, Richard C.

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