Value and Limitations of Measuring HER-2 Extracellular Domain in the Serum of Breast Cancer Patients von LEARY, Alexandra F, HANNA, Wedad M, VAN DE VIJVER, Marc J, PENAULT-LLORCA, Frederique, RÜSCHOFF, Josef, OSAMURA, Robert Y, BILOUS, Michael, DOWSETT, Mitch

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Clinical trials update: endocrine and biological therapy combinations in the treatment of breast cancer von Leary, Alexandra F, Sirohi, Bhawna, Johnston, Stephen R D

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Lapatinib Restores Hormone Sensitivity with Differential Effects on Estrogen Receptor Signaling in Cell Models of Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer wi... von LEARY, Alexandra F, DRURY, Suzanne, DETRE, Simone, PANCHOLI, Sunil, LYKKESFELDT, Anne E, MARTIN, Lesley-Ann, DOWSETT, Mitch, JOHNSTON, Stephen R. D

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Establishing an EGFR mutation screening service for non-small cell lung cancer – Sample quality criteria and candidate histological predictors von Leary, Alexandra F, Castro, David Gonzalez de, Nicholson, Andrew G, Ashley, Sue, Wotherspoon, Andrew, O’Brien, Mary E.R, Popat, Sanjay

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Neoadjuvant chemotherapy (NACT) increases immune infiltration and programmed death-ligand 1 (PD-L1) expression in epithelial ovarian cancer (EOC) von Mesnage, S.J.L., Auguste, A., Genestie, C., Dunant, A., Pain, E., Drusch, F., Gouy, S., Morice, P., Bentivegna, E., Lhomme, C., Pautier, P., Michels, J., Le Formal, A., Cheaib, B., Adam, J., Leary, A.F.

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Impact of young age on platinum response in women with epithelial ovarian cancer: Results of a large single-institution registry von Michels, Judith, Genestie, Catherine, Dunant, Ariane, Caron, Olivier, Lanoy, Emilie, Colomba, Emeline, Pommeret, Fanny, Rey, Annie, Gouy, Sébastien, Duvillard, Pierre, Teuff, Gwenael Le, Larue, Christine, Savoye, Aude Marie, Lhommé, Catherine, Leary, Alexandra, Morice, Philippe, Pautier, Patricia

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Abstract LB-222: Lapatinib has antiproliferative effects in both HER2 positive (+) and HER2 negative (-) breast cancer (BC): results from the MAPLE short-term pre-surgical trial (C... von Evans, Abigail, Leary, Alexandra F., Johnston, Stephen, A'Hern, Roger, Bliss, Judith M., Hills, Margaret Joy, Harper-Wynne, Catherine, Bundred, Nigel, Coombes, Gill, Sahoo, Rashmita, Detre, Simone, Smith, Ian E., Dowsett, Mitch

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Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibitio... von Eggink, Florine A., Van Gool, Inge C., Leary, Alexandra, Pollock, Pamela M., Crosbie, Emma J., Mileshkin, Linda, Jordanova, Ekaterina S., Adam, Julien, Freeman-Mills, Luke, Church, David N., Creutzberg, Carien L., De Bruyn, Marco, Nijman, Hans W., Bosse, Tjalling

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Identification of Effective Strategies to Promote Language in Deaf Children With Cochlear Implants von Cruz, Ivette, Quittner, Alexandra L., Marker, Craig, DesJardin, Jean L.

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Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study von Callaby, Helen, Luintel, Akish, Beynon, William, Bond, Helena, O'Hara, Geraldine, Peters, Joanna R, Payne, Lara, Mody, Nisha, Rampling, Tommy, Dunning, Jake, Milligan, Iain D, Lamb, Lucy E, Moores, Rachel C, Irish, Dianne, Jalal, Hamid, Mack, Damien, Miller, Robert, Gil, Eliza, Spicer, Wendy, Furneaux, Jenna, Matthew, Jones, Matthew, Hannah J, Vipond, Richard, Gibney, Barry, Hunter, Michael, McCarty, Emma, Li, Kathy, McGinnity, Katherine, Culbert, Carly, Jeong, Eunjin, Dyche, Jessica, McCormick, Hannah, Heskin, Joseph, Walters, Yasmin, Tung, Hsiu, Patel, Kinjal, Henderson, Merle, Peres, Edu, Dickinson, Molly, Mughal, Nabeela, Hughes, Stephen, Chitlangia, Shrada, Heaslip, Vivian, Girometti, Nicolo, Pond, Marcus, Naidu, Vasanth V, Brown, Aisling, Goodman, Anna, Newsholme, William, Bilinska, Julia, SA Pinto, Pedro, Haque, Sarah, Gideon, Tseday, Jerome-oboh, Damilola, Rimmer, Stephanie, Dosekun, Olamide, Davies, Ella, Taylor, Lauren, Alagratnam, Jasmini, Payne, Lara V S, Nic Fhogartaigh, Caoimhe, Bholah, Salmaan, Lampejo, Temi, Middleditch, Holly, Mulka, Larissa, Downey, Michael R, McCallum, Craig I, Ratcliffe, Libuse, Gould, Susie, Cruise, James, Keating, Grace, Harrison, Daniel, Willoughby, Shay, Jarvis, Anthony, Smielewska, Anna, Foley, Fiona, Friday, Dawn, Joseph, Deepa, Salinas, Jason, Ume, Uchenna, Wallis, Gabriel, Johnson, Leann, Ustianowski, Andrew, Dancso, Balazs, Ghosh, Samit, Goodwin, Lynsey, Murray, Charlotte, Salthouse, Kirstie, Mulligan, Robert, Brolly, Jacob, Nwajiugo, Paul, Schmid, Matthias, Schwab, Uli, Payne, Brendan, Karageorgopoulos, Drosos E, Dagens, Andrew B, Farrow, Sam, Bicanic, Tihana, Riordan, Andrew, Whittaker, Elizabeth

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Low probability of disease cure in advanced ovarian carcinomas before the PARP inhibitor era von You, Benoit, Van Wagensveld, Lilian, Tod, Michel, Sonke, Gabe S., Horlings, Hugo M., Kruitwagen, R. F. P. M., Du Bois, Andreas, Selle, Frédéric, Perren, Timothy, Pfisterer, Jacobus, Joly, Florence, Cook, Adrian, Kaminsky, Marie Christine, Wollschlaeger, Kerstin, Lortholary, Alain, Tome, Oliver, Leary, Alexandra, Freyer, Gilles, Van Der Aa, Maaike, Colomban, Olivier

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ENIGMA-Evidence-based network for the interpretation of germline mutant alleles: An international initiative to evaluate risk and clinical significance associated with sequence var... von Spurdle, Amanda B., Healey, Sue, Devereau, Andrew, Hogervorst, Frans B. L., Monteiro, Alvaro N. A., Nathanson, Katherine L., Radice, Paolo, Stoppa-Lyonnet, Dominique, Tavtigian, Sean, Wappenschmidt, Barbara, Couch, Fergus J., Goldgar, David E.

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Association of Tumor Mutational Burden and Microsatellite Instability With Response and Outcomes in Patients With Urothelial Carcinoma Treated With Immune Checkpoint Inhibitor von Bakaloudi, Dimitra Rafailia, Talukder, Rafee, Makrakis, Dimitrios, Diamantopoulos, Leonidas, Enright, Thomas, Leary, Jacob B., Patgunarajah, Ubenthira, Thomas, Vinay M., Swami, Umang, Agarwal, Neeraj, Jindal, Tanya, Koshkin, Vadim S., Brown, Jason R., Barata, Pedro, Murgić, Jure, Miletić, Marija, Johnson, Jeffrey, Zakharia, Yousef, Hui, Gavin, Drakaki, Alexandra, Duran, Ignacio, Buznego, Lucia A., Barrera, Rafael M., Castañeda, David M., Rey-Cárdenas, Macarena, Castellano, Daniel, Nguyen, Charles B., Park, Joseph J., Alva, Ajjai, McKay, Rana R., Stewart, Tyler F., Epstein, Ilana B., Bellmunt, Joaquim, Wright, Jonathan L., Gupta, Shilpa, Grivas, Petros, Khaki, Ali Raza

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Abstract 774: Anti-Müllerian hormone type II receptor (AMHRII) found expressed in human non-gynecological solid tumors, suggesting potential broader applications for anti-AMHRII-ba... von Barret, Jean-Marc M., Meseure, Didier, Bataillon, Guillaume, Andersson, Noora, Auguste, Aurélie, Dubreuil, Olivier, Färkkilä, Anniina, Perrial, Emeline, Bossard, Celine, Loison, Emily, Jarry, Anne, Nicolas, André, Lemée, Fanny, Gaillard, Solenne, Lahmar, Mehdi, Anttonen, Mikko, Champenois, Gabriel, Dumontet, Charles, Ray-Coquard, Isabelle, Leary, Alexandra, Tabah-Fisch, Isabelle, Vincent-Salomon, Anne, Prost, Jean-François F.

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A randomized, open-label, phase II study of anti-NaPi2b antibody-drug conjugate (ADC) lifastuzumab (Lifa) vedotin (DNIB0600A) compared to pegylated liposomal doxorubicin (PLD) in p... von Banerjee, Susana N., Oza, Amit M., Birrer, Michael J., Hamilton, Erika Paige, Hasan, Jurjees, Leary, Alexandra, Moore, Kathleen N., Mackowiak-Matejczyk, Beata, Pikiel, Joanna, Ray-Coquard, Isabelle, Trask, Peter, Lin, Kedan, Vaze, Anjali, Choi, YounJeong, Marsters, Jim, Maslyar, Daniel J., Lemahieu, Vanessa, Wang, Yulei, Humke, Eric William, Liu, Joyce F.

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