Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system von Leakey, Julian E.A., Cunny, Helen C., Bazare, Johnny, Webb, Peggy J., Feuers, Richie J., Duffy, Peter H., Hart, Ronald W.

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The Physiologic, Neurologic, and Behavioral Effects of Caloric Restriction Related to Aging, Disease, and Environmental Factors von Duffy, P.H., Leakey, J.E.A., Pipkin, J.L., Turturro, A., Hart, R.W.

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Adaptive role of caloric intake on the degenerative disease processes von HART, R. W, DIXIT, R, PIPKIN, J, LI, S. Y, SENG, J, TURTURRO, A, LEAKEY, J. E. A, FEUERS, R, DUFFY, P, BUFFINGTON, C, COWAN, G, LEWIS, S

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The inadequacy of perinatal glucuronidation: immunoblot analysis of the developmental expression of individual UDP-glucuronosyltransferase isoenzymes in rat and human liver microso... von COUGHTRIE, M. W. H, BURCHELL, B, LEAKEY, J. E. A, HUME, R

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An improved assay technique for uridine diphosphate glucuronosyltransferase activity towards 5-hydroxytryptamine and some properties of the enzyme von Leakey, J E

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Development of multiple activities of UDP-glucuronyltransferase in human liver von Leakey, J E, Hume, R, Burchell, B

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Dietary restriction in humans: report on the Little Rock Conference on the value, feasibility, and parameters of a proposed study von Hass, Bruce S., Lewis, Sherry M., Duffy, Peter H., Ershler, William, Feuers, Ritchie J., Good, Robert A., Ingram, Donald K., Lane, Mark A., Leakey, Julian E.A., Lipschitz, David, Poehlman, Eric T., Roth, George S., Sprott, Richard L., Sullivan, Dennis H., Turturro, Angelo, Verdery, Roy B., Walford, Roy L., Weindruch, Richard, Yu, Byung P., Hart, Ronald W.

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Phase I and phase II enzymes produced by Cunninghamella elegans for the metabolism of xenobiotics von Zhang, D, Yang, Y, Leakey, J.E.A, Cerniglia, C.E

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The effect of propylene glycol on the P450-dependent metabolism of acetaminophen and other chemicals in subcellular fractions of mouse liver von Snawder, J.E., Benson, R.W., Leakey, J.E.A., Roberts, D.W.

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A mechanistic basis for the beneficial effects of caloric restriction on longevity and disease : Consequences for the interpretation of rodent toxicity studies: Symposium: nutritio... von LEAKEY, J. E. A, SENG, J. E, BARNAS, C. R, BAKER, V. M, HART, R. W

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The effect of aging and dietary restriction on the retinoylation of nuclear matrix proteins in rats von Pipkin, J. L., Hinson, W., Lyn-Cook, L. E., Duffy, P. H., Feuers, R. J., Leakey, J. E. A., Aly, K. B., Hart, R. W., Casciano, D. A.

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P48: A novel nuclear protein possibly associated with aging and mortality von Pipkin, J. L., Hinson, W. G., Lyn-Cook, L. E., Duffy, P. H., Feuers, R. J., Leakey, J. E. A., Aly, K. B., Hart, R. W., Casciano, D. A.

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Susceptibility to phenobarbital promotion of hepatotumorigenesis : correlation with differential expression and induction of hepatic drug metabolizing enzymes in heavy and light ma... von WOLFF, G. L, LEAKEY, J. E. A, BAZARE, J. J, HARMON, J. R, WEBB, P. J, LAW, M. G

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Synthesis and stability of isotopically labeled p-chloro-m-xylenol (PCMX) von REEPMEYER, J. C, ZIELINSKI, W. L, LEAKEY, J. E. A, YING SI

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Precocious development of cytochrome P-450 in neonatal rat liver after glucocorticoid treatment von Leakey, J E, Fouts, J R

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Dexamethasone induces hepatic cytochrome P-450 content and increases certain monooxygenase activities in rhesus monkey fetuses von Leakey, Julian E.A., Althaus, Zelda R., Bailey, John R., Slikker, William

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Dexamethasone increases UDP-glucuronyltransferase activity towards bilirubin, oestradiol and testosterone in foetal liver from rhesus monkey during late gestation von Leakey, J E, Althaus, Z R, Bailey, J R, Slikker, Jr, W

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UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys von Leakey, J E, Althaus, Z R, Bailey, J R, Slikker, Jr, W

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Human cytochrome P450IIA3 : cDNA sequence, role of the enzyme in the metabolic activation of promutagen, comparison to nitrosamine activation by human cytochrome P450IIE1 von CRESPI, C. L, PENMAN, B. W, LANGENBACH, R, LEAKEY, J. A. E, ARLOTTO, M. P, STARK, A, PARKINSON, A, TURNER, T, STEIMEL, D. T, RUDO, K, DAVIES, R. L

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Precocious development of uridine diphosphate glucuronosyltransferase activity during organ culture of foetal rat liver in the presence of glucocorticoids von Wishart, G J, Goheer, M A, Leakey, J E, Dutton, G J

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