Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria von Mao, Dat P, Wewers, Mark D, Miao, Edward A, Warren, Sarah E, Treuting, Piper M, Leaf, Irina A, Dors, Monica, Sarkar, Anasuya, Aderem, Alan

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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome von Miao, Edward A, Mao, Dat P, Yudkovsky, Natalya, Bonneau, Richard, Lorang, Cynthia G, Warren, Sarah E, Leaf, Irina A, Aderem, Alan

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Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury von Leaf, Irina A, Nakagawa, Shunsaku, Johnson, Bryce G, Cha, Jin Joo, Mittelsteadt, Kristen, Guckian, Kevin M, Gomez, Ivan G, Altemeier, William A, Duffield, Jeremy S

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Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium von Aachoui, Youssef, Kajiwara, Yuji, Leaf, Irina A., Mao, Dat, Ting, Jenny P.-Y., Coers, Jörn, Aderem, Alan, Buxbaum, Joseph D., Miao, Edward A.

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Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney von Puranik, Amrutesh S., Leaf, Irina A., Jensen, Mark A., Hedayat, Ahmad F., Saad, Ahmad, Kim, Ki-Wook, Saadalla, Abdulrahman M., Woollard, John R., Kashyap, Sonu, Textor, Stephen C., Grande, Joseph P., Lerman, Amir, Simari, Robert D., Randolph, Gwendalyn J., Duffield, Jeremy S., Lerman, Lilach O.

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Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2 von Warren, Sarah E, Armstrong, Abraham, Hamilton, M Kristina, Mao, Dat P, Leaf, Irina A, Miao, Edward A, Aderem, Alan

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What can target kidney fibrosis? von Leaf, Irina A, Duffield, Jeremy S

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Interleukin-1 β Activates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis von Lemos, Dario R, McMurdo, Michael, Karaca, Gamze, Wilflingseder, Julia, Leaf, Irina A, Gupta, Navin, Miyoshi, Tomoya, Susa, Koichiro, Johnson, Bryce G, Soliman, Kirolous, Wang, Guanghai, Morizane, Ryuji, Bonventre, Joseph V, Duffield, Jeremy S

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Caspase-11 Protects Against Bacteria That Escape the Vacuole von Aachoui, Youssef, Leaf, Irina A., Hagar, Jon A., Fontana, Mary F., Campos, Cristine G., Zak, Daniel E., Tan, Michael H., Cotter, Peggy A., Vance, Russell E., Aderem, Alan, Miao, Edward A.

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Systems biology platform for efficient development and translation of multitargeted therapeutics von Azer, Karim, Leaf, Irina

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Tu1542 CREATION OF A MULTI-FACILITY, MULTI-SPECIALTY, DEDICATED LIVER TUMOR BOARD AND ITS IMPACT ON SURVIVAL AND TIMELINESS OF CARE von Abramowitz, Binyamin R., Horowitz, Judah, Schwartz, David L., Kwon, William, Somrov, Serge, Lee, Tae Hoon, Hunt, Kristel K., Desantis, Mark, Rogers, Kevin M., Miller, Jeffrey, Heimann, David M., Lancellotti, Frank, Lenza, Christopher, Leaf, Andrea N., Mehta, Rakesh, Khmelnitsky, Irina, DeFalco, Colleen, Chander, Bala R., Wallach, Jonathan B., Neculiseanu, Elvira, Kirtich, Sabina, DiLeo, Daniel A., Aytaman, Ayse

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The mammalian twisted gastrulation gene functions in foregut and craniofacial development von Petryk, Anna, Anderson, Ryan M, Jarcho, Michael P, Leaf, Irina, Carlson, Cathy S, Klingensmith, John, Shawlot, William, O'Connor, Michael B

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Non-canonical inflammasome activation of Caspase-11 protects against cytosolic bacteria (P1262) von Aachoui, Youssef, Leaf, Irina, Hagar, Jon, Fontana, Mary, Campos, Cristine, Zak, Daniel, Tan, Michael, Cotter, Peggy, Vance, Russell, Aderem, Alan, Miao, Edward

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Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria (111.33) von Miao, Edward, Leaf, Irina, Treuting, Piper, Mao, Dat, Sarkar, Anasuya, Wewers, Mark, Aderem, Alan

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Sfrp5 is not essential for axis formation in the mouse von Leaf, Irina, Tennessen, Jason, Mukhopadhyay, Mahua, Westphal, Heiner, Shawlot, William

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Meta-Ranker: Efficient Design of Combination Drug Products for Complex Diseases von Shirodkar, Shreya, Russell, Matthew, Xing, Shuran, Nitzel, Arianna, Vairinhos, Franklin, Patel, Manish, Leaf, Irina, Cokol, Murat, Azer, Karim

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BIOMARKERS OF AMINO ACID COMPOSITION TREATMENT RESPONSE IN LONG COVID von PRADINES, Joel, LEAF, Irina, LAVERY, Karen, AZER, Karim

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IRAK4 inhibiting agents von Lucas, Brian, Vessels, Jeffrey, Leaf, Irina, Chan, Timothy, Genung, Nathan, Jenkins, Tracy, Kumaravel, Gnanasambandam, Thomas, Jermaine, Meissner, Robert, Guckian, Kevin M, Lyssikatos, Joseph P, Duffield, Jeremy

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Agentes inhibidores de irak4 von GUCKIAN, Kevin, JENKINS, Tracy, LYSSIKATOS, Joseph P, THOMAS, Jermaine, LEAF, Irina, MEISSNER, Robert, DUFFIELD, Jeremy, KUMARAVEL, Gnanasambandam, GENUNG, Nathan, VESSELS, Jeffrey, LUCAS, Brian, CHAN, Timothy

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IRAK4 INHIBITING AGENTS von GUCKIAN, Kevin, JENKINS, Tracy, THOMAS, Jermaine, LEAF, Irina, MEISSNER, Robert, DUFFIELD, Jeremy, KUMARAVEL, Gnanasambandam, GENUNG, Nathan, VESSELS, Jeffrey, LUCAS, Brian, LYSSIKATOS, Joseph, P, CHAN, Timothy

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