Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria von Mao, Dat P, Wewers, Mark D, Miao, Edward A, Warren, Sarah E, Treuting, Piper M, Leaf, Irina A, Dors, Monica, Sarkar, Anasuya, Aderem, Alan

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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome von Miao, Edward A, Mao, Dat P, Yudkovsky, Natalya, Bonneau, Richard, Lorang, Cynthia G, Warren, Sarah E, Leaf, Irina A, Aderem, Alan

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Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury von Leaf, Irina A, Nakagawa, Shunsaku, Johnson, Bryce G, Cha, Jin Joo, Mittelsteadt, Kristen, Guckian, Kevin M, Gomez, Ivan G, Altemeier, William A, Duffield, Jeremy S

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Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium von Aachoui, Youssef, Kajiwara, Yuji, Leaf, Irina A., Mao, Dat, Ting, Jenny P.-Y., Coers, Jörn, Aderem, Alan, Buxbaum, Joseph D., Miao, Edward A.

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Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney von Puranik, Amrutesh S., Leaf, Irina A., Jensen, Mark A., Hedayat, Ahmad F., Saad, Ahmad, Kim, Ki-Wook, Saadalla, Abdulrahman M., Woollard, John R., Kashyap, Sonu, Textor, Stephen C., Grande, Joseph P., Lerman, Amir, Simari, Robert D., Randolph, Gwendalyn J., Duffield, Jeremy S., Lerman, Lilach O.

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Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2 von Warren, Sarah E, Armstrong, Abraham, Hamilton, M Kristina, Mao, Dat P, Leaf, Irina A, Miao, Edward A, Aderem, Alan

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What can target kidney fibrosis? von Leaf, Irina A, Duffield, Jeremy S

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Interleukin-1 β Activates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis von Lemos, Dario R, McMurdo, Michael, Karaca, Gamze, Wilflingseder, Julia, Leaf, Irina A, Gupta, Navin, Miyoshi, Tomoya, Susa, Koichiro, Johnson, Bryce G, Soliman, Kirolous, Wang, Guanghai, Morizane, Ryuji, Bonventre, Joseph V, Duffield, Jeremy S

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Caspase-11 Protects Against Bacteria That Escape the Vacuole von Aachoui, Youssef, Leaf, Irina A., Hagar, Jon A., Fontana, Mary F., Campos, Cristine G., Zak, Daniel E., Tan, Michael H., Cotter, Peggy A., Vance, Russell E., Aderem, Alan, Miao, Edward A.

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