The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety von Bilyk, Oksana, Samborskyy, Markiyan, Leadlay, Peter F

Volltext

Methyltransferases of gentamicin biosynthesis von Li, Sicong, Guo, Junhong, Reva, Anna, Huang, Fanglu, Xiong, Binbin, Liu, Yuanzhen, Deng, Zixin, Leadlay, Peter F., Sun, Yuhui

Volltext

Recent advances in the field of bioactive tetronates von Vieweg, Laura, Reichau, Sebastian, Schobert, Rainer, Leadlay, Peter F, Süssmuth, Roderich D

Volltext

C-Nucleoside Formation in the Biosynthesis of the Antifungal Malayamycin A von Hong, Hui, Samborskyy, Markiyan, Zhou, Yongjun, Leadlay, Peter F.

Volltext

The biosynthetic pathway to tetromadurin (SF2487/A80577), a polyether tetronate antibiotic von Little, Rory F., Samborskyy, Markiyan, Leadlay, Peter F.

Volltext

A Common Origin for Guanidinobutanoate Starter Units in Antifungal Natural Products von Hong, Hui, Fill, Taicia, Leadlay, Peter F.

Volltext

Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition von Zhai, Guifa, Zhu, Yan, Sun, Guo, Zhou, Fan, Sun, Yangning, Hong, Zhou, Dong, Chuan, Leadlay, Peter F., Hong, Kui, Deng, Zixin, Zhou, Fuling, Sun, Yuhui

Volltext

An Amidinohydrolase Provides the Missing Link in the Biosynthesis of Amino Marginolactone Antibiotics von Hong, Hui, Samborskyy, Markiyan, Lindner, Frederick, Leadlay, Peter F.

Volltext

Broadening substrate specificity of a chain-extending ketosynthase through a single active-site mutation von Murphy, Annabel C, Hong, Hui, Vance, Steve, Broadhurst, R. William, Leadlay, Peter F

Volltext

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338 von Oliynyk, Markiyan, Samborskyy, Markiyan, Lester, John B, Mironenko, Tatiana, Scott, Nataliya, Dickens, Shilo, Haydock, Stephen F, Leadlay, Peter F

Volltext

Production of Isoflavone Metabolites and Their Microbial Transformation by a Soil-Derived Saccharopolyspora antimicrobica DSMZ45119 von Xu, Jing, Ye, Jing-Jing, Zhou, Dong-Dong, Zhang, Xue-Xia, Leadlay, Peter-F.

Volltext

Isoafricanol synthase from Streptomyces malaysiensis von Rabe, Patrick, Samborskyy, Markiyan, Leadlay, Peter F, Dickschat, Jeroen S

Volltext

Site-Specific Recombination Strategies for Engineering Actinomycete Genomes von HERRMANN, Simone, SIEGL, Theresa, LUZHETSKA, Marta, PETZKE, Lutz, JILG, Caroline, WELLE, Elisabeth, ERB, Annette, LEADLAY, Peter F, BECHTHOLD, Andreas, LUZHETSKYY, Andriy

Volltext

Sarpeptins A and B, Lipopeptides Produced by Streptomyces sp. KO-7888 Overexpressing a Specific SARP Regulator von Koomsiri, Wilaiwan, Inahashi, Yuki, Leetanasaksakul, Kantinan, Shiomi, Kazuro, Takahashi, Yo̅ko, O̅mura, Satoshi, Samborskyy, Markiyan, Leadlay, Peter F, Wattana-Amorn, Pakorn, Thamchaipenet, Arinthip, Nakashima, Takuji

Volltext

Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation von Guenin-Macé, Laure, Veyron-Churlet, Romain, Thoulouze, Maria-Isabel, Romet-Lemonne, Guillaume, Hong, Hui, Leadlay, Peter F, Danckaert, Anne, Ruf, Marie-Thérèse, Mostowy, Serge, Zurzolo, Chiara, Bousso, Philippe, Chrétien, Fabrice, Carlier, Marie-France, Demangel, Caroline

Volltext

Unusual Acetylation-Elimination in the Formation of Tetronate Antibiotics von Kanchanabanca, Chompoonik, Tao, Weixin, Hong, Hui, Liu, Yajing, Hahn, Frank, Samborskyy, Markiyan, Deng, Zixin, Sun, Yuhui, Leadlay, Peter F.

Volltext

Structural Basis of the Selectivity of GenN, an Aminoglycoside N‑Methyltransferase Involved in Gentamicin Biosynthesis von Bury, Priscila dos Santos, Huang, Fanglu, Li, Sicong, Sun, Yuhui, Leadlay, Peter F, Dias, Marcio Vinicius Bertacine

Volltext

Directed Accumulation of Anticancer Depsipeptides by Characterization of Neoantimycins Biosynthetic Pathway and an NADPH-Dependent Reductase von Zhou, Yongjun, Lin, Xiao, Williams, Simon R, Liu, Liyun, Shen, Yaoyao, Wang, Shu-Ping, Sun, Fan, Xu, Shihai, Deng, Hai, Leadlay, Peter F, Lin, Hou-Wen

Volltext

Glycodiversification of gentamicins through in vivo glycosyltransferase swapping enabled the creation of novel hybrid aminoglycoside antibiotics with potent activity and low ototox... von Jian, Xinyun, Wang, Cheng, Wu, Shijuan, Sun, Guo, Huang, Chuan, Qiu, Chengbing, Liu, Yuanzheng, Leadlay, Peter F., Liu, Dong, Deng, Zixin, Zhou, Fuling, Sun, Yuhui

Volltext

Mycolactone diffuses from Mycobacterium ulcerans-infected tissues and targets mononuclear cells in peripheral blood and lymphoid organs von Hong, Hui, Coutanceau, Emmanuelle, Leclerc, Marion, Caleechurn, Laxmee, Leadlay, Peter F, Demangel, Caroline

Volltext