CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma von Steele, Colin W., Karim, Saadia A., Leach, Joshua D.G., Bailey, Peter, Upstill-Goddard, Rosanna, Rishi, Loveena, Foth, Mona, Bryson, Sheila, McDaid, Karen, Wilson, Zena, Eberlein, Catherine, Candido, Juliana B., Clarke, Mairi, Nixon, Colin, Connelly, John, Jamieson, Nigel, Carter, C. Ross, Balkwill, Frances, Chang, David K., Evans, T.R. Jeffry, Strathdee, Douglas, Biankin, Andrew V., Nibbs, Robert J.B., Barry, Simon T., Sansom, Owen J., Morton, Jennifer P.

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Fumarate induces redox-dependent senescence by modifying glutathione metabolism von Zheng, Liang, Cardaci, Simone, Jerby, Livnat, MacKenzie, Elaine D., Sciacovelli, Marco, Johnson, T. Isaac, Gaude, Edoardo, King, Ayala, Leach, Joshua D. G., Edrada-Ebel, RuAngelie, Hedley, Ann, Morrice, Nicholas A., Kalna, Gabriela, Blyth, Karen, Ruppin, Eytan, Frezza, Christian, Gottlieb, Eyal

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CXCR2 inhibition suppresses acute and chronic pancreatic inflammation von Steele, Colin W, Karim, Saadia A, Foth, Mona, Rishi, Loveena, Leach, Joshua DG, Porter, Ross J, Nixon, Colin, Jeffry Evans, TR, Carter, C Ross, Nibbs, Robert JB, Sansom, Owen J, Morton, Jennifer P

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RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome von Rooney, Nicholas, Mason, Susan M, McDonald, Laura, Däbritz, J Henry M, Campbell, Kirsteen J, Hedley, Ann, Howard, Steven, Athineos, Dimitris, Nixon, Colin, Clark, William, Leach, Joshua D G, Sansom, Owen J, Edwards, Joanne, Cameron, Ewan R, Blyth, Karen

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Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest von Dikovskaya, Dina, Cole, John J., Mason, Susan M., Nixon, Colin, Karim, Saadia A., McGarry, Lynn, Clark, William, Hewitt, Rachael N., Sammons, Morgan A., Zhu, Jiajun, Athineos, Dimitris, Leach, Joshua D.G., Marchesi, Francesco, van Tuyn, John, Tait, Stephen W., Brock, Claire, Morton, Jennifer P., Wu, Hong, Berger, Shelley L., Blyth, Karen, Adams, Peter D.

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Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features von Flanagan, Dustin J., Amirkhah, Raheleh, Vincent, David F., Gunduz, Nuray, Gentaz, Pauline, Cammareri, Patrizia, McCooey, Aoife J., McCorry, Amy M. B., Fisher, Natalie C., Davis, Hayley L., Ridgway, Rachel A., Lohuis, Jeroen, Leach, Joshua D. G., Jackstadt, Rene, Gilroy, Kathryn, Mariella, Elisa, Nixon, Colin, Clark, William, Hedley, Ann, Markert, Elke K., Strathdee, Douglas, Bartholin, Laurent, Redmond, Keara L., Kerr, Emma M., Longley, Daniel B., Ginty, Fiona, Cho, Sanghee, Coleman, Helen G., Loughrey, Maurice B., Bardelli, Alberto, Maughan, Timothy S., Campbell, Andrew D., Lawler, Mark, Leedham, Simon J., Barry, Simon T., Inman, Gareth J., van Rheenen, Jacco, Dunne, Philip D., Sansom, Owen J.

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Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features von Flanagan, Dustin J., Amirkhah, Raheleh, Vincent, David F., Gunduz, Nuray, Gentaz, Pauline, Cammareri, Patrizia, McCooey, Aoife J., McCorry, Amy M. B., Fisher, Natalie C., Davis, Hayley L., Ridgway, Rachel A., Lohuis, Jeroen, Leach, Joshua D. G., Jackstadt, Rene, Gilroy, Kathryn, Mariella, Elisa, Nixon, Colin, Clark, William, Hedley, Ann, Markert, Elke K., Strathdee, Douglas, Bartholin, Laurent, Redmond, Keara L., Kerr, Emma M., Longley, Daniel B., Ginty, Fiona, Cho, Sanghee, Coleman, Helen G., Loughrey, Maurice B., Bardelli, Alberto, Maughan, Timothy S., Campbell, Andrew D., Lawler, Mark, Leedham, Simon J., Barry, Simon T., Inman, Gareth J., van Rheenen, Jacco, Dunne, Philip D., Sansom, Owen J.

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Loss of Cxcr2 in Myeloid Cells Promotes Tumour Progression and T Cell Infiltration in Invasive Bladder Cancer von Ismail, Nur Faezah Binti, Foth, Mona, Yousef, Amal Rahil Elgaddafi, Cui, Ningxuan, Leach, Joshua D.G., Jamieson, Thomas, Karim, Saadia A., Salmond, Jonathan M., Morton, Jennifer P., Iwata, Tomoko

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Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis von Leach, Joshua D. G., Vlahov, Nikola, Tsantoulis, Petros, Ridgway, Rachel A., Flanagan, Dustin J., Gilroy, Kathryn, Sphyris, Nathalie, Vázquez, Ester G., Vincent, David F., Faller, William J., Hodder, Michael C., Raven, Alexander, Fey, Sigrid, Najumudeen, Arafath K., Strathdee, Douglas, Nixon, Colin, Hughes, Mark, Clark, William, Shaw, Robin, van Hooff, Sander R., Huels, David J., Medema, Jan Paul, Barry, Simon T., Frame, Margaret C., Unciti-Broceta, Asier, Leedham, Simon J., Inman, Gareth J., Jackstadt, Rene, Thompson, Barry J., Campbell, Andrew D., Tejpar, Sabine, Sansom, Owen J.

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Sialolipoma of the parotid salivary gland in two dogs von Rodiño Tilve, Verónica, Finck, Marlene, Leach, Joshua DG, Macfarlane, Michael J

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Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania von Smits, Samuel A., Leach, Jeff, Sonnenburg, Erica D., Gonzalez, Carlos G., Lichtman, Joshua S., Reid, Gregor, Knight, Rob, Manjurano, Alphaxard, Changalucha, John, Elias, Joshua E., Dominguez-Bello, Maria Gloria, Sonnenburg, Justin L.

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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis von Jackstadt, Rene, van Hooff, Sander R., Leach, Joshua D., Cortes-Lavaud, Xabier, Lohuis, Jeroen O., Ridgway, Rachel A., Wouters, Valérie M., Roper, Jatin, Kendall, Timothy J., Roxburgh, Campbell S., Horgan, Paul G., Nixon, Colin, Nourse, Craig, Gunzer, Matthias, Clark, William, Hedley, Ann, Yilmaz, Omer H., Rashid, Mamunur, Bailey, Peter, Biankin, Andrew V., Campbell, Andrew D., Adams, David J., Barry, Simon T., Steele, Colin W., Medema, Jan Paul, Sansom, Owen J.

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Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer von Gay, David M., Ridgway, Rachel A., Müller, Miryam, Hodder, Michael C., Hedley, Ann, Clark, William, Leach, Joshua D., Jackstadt, Rene, Nixon, Colin, Huels, David J., Campbell, Andrew D., Bird, Thomas G., Sansom, Owen J.

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Operando neutron diffraction reveals mechanisms for controlled strain evolution in 3D printing von Plotkowski, A., Saleeby, K., Fancher, C. M., Haley, J., Madireddy, G., An, K., Kannan, R., Feldhausen, T., Lee, Y., Yu, D., Leach, C., Vaughan, J., Babu, S. S.

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MNK Inhibition Sensitizes KRAS -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression von Knight, John R P, Alexandrou, Constantinos, Skalka, George L, Vlahov, Nikola, Pennel, Kathryn, Officer, Leah, Teodosio, Ana, Kanellos, Georgios, Gay, David M, May-Wilson, Sebastian, Smith, Ewan M, Najumudeen, Arafath K, Gilroy, Kathryn, Ridgway, Rachel A, Flanagan, Dustin J, Smith, Rachael C L, McDonald, Laura, MacKay, Craig, Cheasty, Anne, McArthur, Kerri, Stanway, Emma, Leach, Joshua D, Jackstadt, Rene, Waldron, Joseph A, Campbell, Andrew D, Vlachogiannis, Georgios, Valeri, Nicola, Haigis, Kevin M, Sonenberg, Nahum, Proud, Christopher G, Jones, Neil P, Swarbrick, Martin E, McKinnon, Heather J, Faller, William J, Le Quesne, John, Edwards, Joanne, Willis, Anne E, Bushell, Martin, Sansom, Owen J

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American Gut: an Open Platform for Citizen Science Microbiome Research von McDonald, Daniel, Hyde, Embriette, Debelius, Justine W, Morton, James T, Gonzalez, Antonio, Ackermann, Gail, Aksenov, Alexander A, Behsaz, Bahar, Brennan, Caitriona, Chen, Yingfeng, DeRight Goldasich, Lindsay, Dorrestein, Pieter C, Dunn, Robert R, Fahimipour, Ashkaan K, Gaffney, James, Gilbert, Jack A, Gogul, Grant, Green, Jessica L, Hugenholtz, Philip, Humphrey, Greg, Huttenhower, Curtis, Jackson, Matthew A, Janssen, Stefan, Jeste, Dilip V, Jiang, Lingjing, Kelley, Scott T, Knights, Dan, Kosciolek, Tomasz, Ladau, Joshua, Leach, Jeff, Marotz, Clarisse, Meleshko, Dmitry, Melnik, Alexey V, Metcalf, Jessica L, Mohimani, Hosein, Montassier, Emmanuel, Navas-Molina, Jose, Nguyen, Tanya T, Peddada, Shyamal, Pevzner, Pavel, Pollard, Katherine S, Rahnavard, Gholamali, Robbins-Pianka, Adam, Sangwan, Naseer, Shorenstein, Joshua, Smarr, Larry, Song, Se Jin, Spector, Timothy, Swafford, Austin D, Thackray, Varykina G, Thompson, Luke R, Tripathi, Anupriya, Vázquez-Baeza, Yoshiki, Vrbanac, Alison, Wischmeyer, Paul, Wolfe, Elaine, Zhu, Qiyun, Knight, Rob

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Author Correction: Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer von Gay, David M., Ridgway, Rachel A., Müller, Miryam, Hodder, Michael C., Hedley, Ann, Clark, William, Leach, Joshua D., Jackstadt, Rene, Nixon, Colin, Huels, David J., Campbell, Andrew D., Bird, Thomas G., Sansom, Owen J.

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Intrathecal Gene Therapy for Giant Axonal Neuropathy von Bharucha-Goebel, Diana X., Todd, Joshua J., Saade, Dimah, Norato, Gina, Jain, Minal, Lehky, Tanya, Bailey, Rachel M., Chichester, Jessica A., Calcedo, Roberto, Armao, Diane, Foley, A. Reghan, Mohassel, Payam, Tesfaye, Eshetu, Carlin, Bradley P., Seremula, Beth, Waite, Melissa, Zein, Wadih M., Huryn, Laryssa A., Crawford, Thomas O., Sumner, Charlotte J., Hoke, Ahmet, Heiss, John D., Charnas, Lawrence, Hooper, Jody E., Bouldin, Thomas W., Kang, Elizabeth M., Rybin, Denis, Gray, Steven J., Bönnemann, Carsten G.

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Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction von Sotoodehnia, Nona, Isaacs, Aaron, de Bakker, Paul I W, Dörr, Marcus, Newton-Cheh, Christopher, Nolte, Ilja M, van der Harst, Pim, Müller, Martina, Eijgelsheim, Mark, Alonso, Alvaro, Hicks, Andrew A, Padmanabhan, Sandosh, Hayward, Caroline, Polasek, Ozren, Giovannone, Steven, Fu, Jingyuan, Magnani, Jared W, Marciante, Kristin D, Pfeufer, Arne, Gharib, Sina A, Teumer, Alexander, Li, Man, Bis, Joshua C, Rivadeneira, Fernando, Aspelund, Thor, Köttgen, Anna, Johnson, Toby, Rice, Kenneth, Sie, Mark P S, Wang, Ying A, Klopp, Norman, Fuchsberger, Christian, Wild, Sarah H, Leach, Irene Mateo, Estrada, Karol, Völker, Uwe, Wright, Alan F, Asselbergs, Folkert W, Qu, Jiaxiang, Chakravarti, Aravinda, Sinner, Moritz F, Kors, Jan A, Petersmann, Astrid, Harris, Tamara B, Soliman, Elsayed Z, Munroe, Patricia B, Oostra, Ben A, Cupples, L Adrienne, Perz, Siegfried, de Boer, Rudolf A, Uitterlinden, André G, Völzke, Henry, Spector, Timothy D, Liu, Fang-Yu, Boerwinkle, Eric, Dominiczak, Anna F, Rotter, Jerome I, van Herpen, Gé, Levy, Daniel, van Gilst, Wiek H, Witteman, Jacqueline C M, Kroemer, Heyo K, Kao, W H Linda, Heckbert, Susan R, Meitinger, Thomas, Hofman, Albert, Campbell, Harry, Folsom, Aaron R, van Veldhuisen, Dirk J, Schwienbacher, Christine, O'Donnell, Christopher J, Volpato, Claudia Beu, Caulfield, Mark J, Connell, John M, Launer, Lenore, Lu, Xiaowen, Franke, Lude, Fehrmann, Rudolf S N, te Meerman, Gerard, Groen, Harry J M, Weersma, Rinse K, van den Berg, Leonard H, Wijmenga, Cisca, Ophoff, Roel A, Navis, Gerjan, Rudan, Igor, Snieder, Harold, Wilson, James F, Pramstaller, Peter P, Siscovick, David S, Wang, Thomas J, Gudnason, Vilmundur, van Duijn, Cornelia M, Felix, Stephan B, Fishman, Glenn I, Jamshidi, Yalda, Ch Stricker, Bruno H, Samani, Nilesh J, Kääb, Stefan, Arking, Dan E

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Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis von Leach, Joshua D.G, Vlahov, Nikola, Tsantoulis, Petros, Ridgway, Rachel A, Flanagan, Dustin J, Gilroy, Kathryn, Sphyris, Nathalie, Vazquez, Ester G, Vincent, David F, Faller, William J, Hodder, Michael C, Raven, Alexander, Fey, Sigrid, Najumudeen, Arafath K, Strathdee, Douglas, Nixon, Colin, Hughes, Mark, Clark, William, Shaw, Robin, van Hooff, Sander R, Huels, David J, Medema, Jan Paul, Barry, Simon T, Frame, Margaret C, Unciti-Broceta, Asier, Leedham, Simon J, Inman, Gareth J, Jackstadt, Rene, Thompson, Barry J, Campbell, Andrew D, Tejpar, Sabine, Sansom, Owen J

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