Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1 von Abulwerdi, Fardokht A, Xu, Wenbo, Ageeli, Abeer A, Yonkunas, Michael J, Arun, Gayatri, Nam, Hyeyeon, Schneekloth, John S, Dayie, Theodore Kwaku, Spector, David, Baird, Nathan, Le Grice, Stuart F. J

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Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays von Sztuba-Solinska, Joanna, Shenoy, Shilpa R, Gareiss, Peter, Krumpe, Lauren R. H, Le Grice, Stuart F. J, O’Keefe, Barry R, Schneekloth, John S

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Structural characterization of maternally expressed gene 3 RNA reveals conserved motifs and potential sites of interaction with polycomb repressive complex 2 von Sherpa, Chringma, Rausch, Jason W, Le Grice, Stuart FJ

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Dynamic binding orientations direct activity of HIV reverse transcriptase von Zhuang, Xiaowei, Abbondanzieri, Elio A, Bokinsky, Gregory, Rausch, Jason W, Zhang, Jennifer X, Le Grice, Stuart F. J

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Slide into Action: Dynamic Shuttling of HIV Reverse Transcriptase on Nucleic Acid Substrates von Liu, Shixin, Abbondanzieri, Elio A, Rausch, Jason W, Grice, Stuart F.J. Le, Zhuang, Xiaowei

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The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication von Sherpa, Chringma, Rausch, Jason W, Le Grice, Stuart F J, Hammarskjold, Marie-Louise, Rekosh, David

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Characterizing and circumventing sequence restrictions for synthesis of circular RNA in vitro von Rausch, Jason W, Heinz, William F, Payea, Matthew J, Sherpa, Chringma, Gorospe, Myriam, Le Grice, Stuart F J

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Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity von Tocco, Graziella, Canton, Serena, Laus, Antonio, Caboni, Pierluigi, Le Grice, Stuart F. J, Tramontano, Enzo, Esposito, Francesca

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Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity von Lu, Gaofeng, Lomonosova, Elena, Cheng, Xiaohong, Moran, Eileen A, Meyers, Marvin J, Le Grice, Stuart F J, Thomas, Craig J, Jiang, Jian-kang, Meck, Christine, Hirsch, Danielle R, D'Erasmo, Michael P, Suyabatmaz, Duygu M, Murelli, Ryan P, Tavis, John E

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Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA: a structural scaffold for nuclear, cytoplasmic and viral proteins von Sztuba-Solinska, Joanna, Rausch, Jason W, Smith, Rodman, Miller, Jennifer T, Whitby, Denise, Le Grice, Stuart F J

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Development of Small Molecules with a Noncanonical Binding Mode to HIV‑1 Trans Activation Response (TAR) RNA von Abulwerdi, Fardokht A, Shortridge, Matthew D, Sztuba-Solinska, Joanna, Wilson, Robert, Le Grice, Stuart F. J, Varani, Gabriele, Schneekloth, John S

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Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism von Zhao, Haiyan, Lin, Zihan, Lynn, Anna Y, Varnado, Brittany, Beutler, John A, Murelli, Ryan P, Le Grice, Stuart F J, Tang, Liang

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DNA binding proteins explore multiple local configurations during docking via rapid rebinding von Ganji, Mahipal, Docter, Margreet, Le Grice, Stuart F J, Abbondanzieri, Elio A

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Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6 von Corona, Angela, Meleddu, Rita, Esposito, Francesca, Distinto, Simona, Bianco, Giulia, Masaoka, Takashi, Maccioni, Elias, Menéndez-Arias, Luis, Alcaro, Stefano, Le Grice, Stuart F J, Tramontano, Enzo

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Multimode, Cooperative Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors von Kessl, Jacques J., Jena, Nivedita, Koh, Yasuhiro, Taskent-Sezgin, Humeyra, Slaughter, Alison, Feng, Lei, de Silva, Suresh, Wu, Li, Le Grice, Stuart F.J., Engelman, Alan, Fuchs, James R., Kvaratskhelia, Mamuka

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Interplay of primary sequence, position and secondary RNA structure determines alternative splicing of LMNA in a pre-mature aging syndrome von Shilo, Asaf, Tosto, Frances Anne, Rausch, Jason W, Le Grice, Stuart F J, Misteli, Tom

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Autophagy Deregulation in HIV-1-Infected Cells Increases Extracellular Vesicle Release and Contributes to TLR3 Activation von DeMarino, Catherine, Cowen, Maria, Williams, Anastasia, Khatkar, Pooja, Abulwerdi, Fardokht A, Henderson, Lisa, Denniss, Julia, Pleet, Michelle L, Luttrell, Delores R, Vaisman, Iosif, Liotta, Lance A, Steiner, Joseph, Le Grice, Stuart F J, Nath, Avindra, Kashanchi, Fatah

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HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules von Khatkar, Pooja, Mensah, Gifty, Ning, Shangbo, Cowen, Maria, Kim, Yuriy, Williams, Anastasia, Abulwerdi, Fardokht A, Zhao, Yunjie, Zeng, Chen, Le Grice, Stuart F J, Kashanchi, Fatah

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Human Immunodeficiency Virus Reverse Transcriptase: 25 Years of Research, Drug Discovery, and Promise von Le Grice, Stuart F.J.

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An Unusual Topological Structure of the HIV-1 Rev Response Element von Fang, Xianyang, Wang, Jinbu, O’Carroll, Ina P., Mitchell, Michelle, Zuo, Xiaobing, Wang, Yi, Yu, Ping, Liu, Yu, Rausch, Jason W., Dyba, Marzena A., Kjems, Jørgen, Schwieters, Charles D., Seifert, Soenke, Winans, Randall E., Watts, Norman R., Stahl, Stephen J., Wingfield, Paul T., Byrd, R. Andrew, Le Grice, Stuart F.J., Rein, Alan, Wang, Yun-Xing

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