A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera von Ugo, Valérie, Lacout, Catherine, Villeval, Jean Luc, Le Couédic, Jean-Pierre, James, Chloé, Vainchenker, William, Berger, Roland, Raslova, Hana, Casadevall, Nicole, Bennaceur-Griscelli, Annelise, Delhommeau, François, Garçon, Loïc, Staerk, Judith, Constantinescu, Stefan N

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TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells von Langlois, Thierry, da Costa Reis Monte‐Mor, Barbara, Lenglet, Gaëlle, Droin, Nathalie, Marty, Caroline, Le Couédic, Jean‐Pierre, Almire, Carole, Auger, Nathalie, Mercher, Thomas, Delhommeau, François, Christensen, Jesper, Helin, Kristian, Debili, Najet, Fuks, François, Bernard, Olivier A., Solary, Eric, Vainchenker, William, Plo, Isabelle

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Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients von Cabagnols, Xénia, Favale, Fabrizia, Pasquier, Florence, Messaoudi, Kahia, Defour, Jean Philippe, Ianotto, Jean Christophe, Marzac, Christophe, Le Couédic, Jean Pierre, Droin, Nathalie, Chachoua, Ilyas, Favier, Remi, Diop, M'boyba Khadija, Ugo, Valérie, Casadevall, Nicole, Debili, Najet, Raslova, Hana, Bellanné-Chantelot, Christine, Constantinescu, Stefan N., Bluteau, Olivier, Plo, Isabelle, Vainchenker, William

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An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia von Plo, Isabelle, Zhang, Yanyan, Le Couédic, Jean-Pierre, Nakatake, Mayuka, Boulet, Jean-Michel, Itaya, Miki, Smith, Steven O, Debili, Najet, Constantinescu, Stefan N, Vainchenker, William, Louache, Fawzia, de Botton, Stéphane

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Proplatelet formation is regulated by the Rho/ROCK pathway von Chang, Yunhua, Auradé, Frédéric, Larbret, Frédéric, Zhang, Yanyan, Le Couedic, Jean-Pierre, Momeux, Laurence, Larghero, Jerôme, Bertoglio, Jacques, Louache, Fawzia, Cramer, Elisabeth, Vainchenker, William, Debili, Najet

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Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis von Delhommeau, François, Dupont, Sabrina, Tonetti, Carole, Massé, Aline, Godin, Isabelle, Couedic, Jean-Pierre Le, Debili, Najet, Saulnier, Patrick, Casadevall, Nicole, Vainchenker, William, Giraudier, Stéphane

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Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors von Pronier, Elodie, Almire, Carole, Mokrani, Hayat, Vasanthakumar, Aparna, Simon, Audrey, da Costa Reis Monte Mor, Barbara, Massé, Aline, Le Couédic, Jean-Pierre, Pendino, Frédéric, Carbonne, Bruno, Larghero, Jérôme, Ravanat, Jean-Luc, Casadevall, Nicole, Bernard, Olivier A., Droin, Nathalie, Solary, Eric, Godley, Lucy A., Vainchenker, William, Plo, Isabelle, Delhommeau, François

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The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera von Dupont, Sabrina, Massé, Aline, James, Chloé, Teyssandier, Irène, Lécluse, Yann, Larbret, Frédéric, Ugo, Valérie, Saulnier, Patrick, Koscielny, Serge, Le Couédic, Jean Pierre, Casadevall, Nicole, Vainchenker, William, Delhommeau, François

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Mutation in TET2 in Myeloid Cancers von Delhommeau, François, Dupont, Sabrina, Valle, Véronique Della, James, Chloé, Trannoy, Severine, Massé, Aline, Kosmider, Olivier, Le Couedic, Jean-Pierre, Robert, Fabienne, Alberdi, Antonio, Lécluse, Yann, Plo, Isabelle, Dreyfus, François J, Marzac, Christophe, Casadevall, Nicole, Lacombe, Catherine, Romana, Serge P, Dessen, Philippe, Soulier, Jean, Viguié, Franck, Fontenay, Michaela, Vainchenker, William, Bernard, Olivier A

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Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis von Chaligné, Ronan, James, Chloé, Tonetti, Carole, Besancenot, Rodolphe, Le Couédic, Jean Pierre, Fava, Fanny, Mazurier, Fréderic, Godin, Isabelle, Maloum, Karim, Larbret, Frédéric, Lécluse, Yann, Vainchenker, William, Giraudier, Stéphane

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Gfi-1B plays a critical role in terminal differentiation of normal and transformed erythroid progenitor cells von Garçon, Loïc, Lacout, Catherine, Svinartchouk, Fédor, Le Couédic, Jean-Pierre, Villeval, Jean-Luc, Vainchenker, William, Duménil, Dominique

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Expression and Function of the Collagen Receptor GPVI during Megakaryocyte Maturation von Lagrue-Lak-Hal, Anne-Hélène, Debili, Najet, Kingbury, Gillian, Lecut, Christelle, Le Couedic, Jean-Pierre, Villeval, Jean-Luc, Jandrot-Perrus, Martine, Vainchenker, William

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Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily von Jandrot-Perrus, Martine, Busfield, Samantha, Lagrue, Anne-Helène, Xiong, Ximing, Debili, Najet, Chickering, Troy, Couedic, Jean-Pierre Le, Goodearl, Andrew, Dussault, Barry, Fraser, Christopher, Vainchenker, William, Villeval, Jean-Luc

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Autonomous megakaryocyte growth in essential thrombocythemia and idiopathic myelofibrosis is not related to a c-mpl mutation or to an autocrine stimulation by Mpl-L von TAKSIN, A. L, LE COUEDIC, J.-P, DUSANTER-FOURT, I, MASSE, A, GIRAUDIER, S, KATZ, A, WENDLING, F, VAINCHENKER, W, CASADEVALL, N, DEBILI, N

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Existence of a differentiation blockage at the stage of a megakaryocyte precursor in the thrombocytopenia and absent radii (TAR) syndrome von Letestu, Rémi, Vitrat, Natacha, Massé, Aline, Couedic, Jean-Pierre Le, Lazar, Vladimir, Rameau, Philippe, Wendling, Françoise, Vuillier, Jacqueline, Boutard, Patrick, Plouvier, Emmanuel, Plasse, Mireille, Favier, Rémi, Vainchenker, William, Debili, Najet

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Mutations in JAK2V617F homologous domain of JAK genes are uncommon in solid tumors von Motté, Nelly, Saulnier, Patrick, Le Couedic, Jean‐Pierre, Soria, Jean‐Charles, Delaloge, Suzette, Boige, Valérie, Pautier, Patricia, Vainchenker, William, Bidart, Jean‐Michel, Villeval, Jean‐Luc

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Role of p21Cip1/Waf1 in cell-cycle exit of endomitotic megakaryocytes von Baccini, Véronique, Roy, Lydia, Vitrat, Natacha, Chagraoui, Hédia, Sabri, Siham, Couedic, Jean-Pierre Le, Debili, Najet, Wendling, Françoise, Vainchenker, William

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Hepatosplenic T-Cell Lymphoma: Sinusal/Sinusoidal Localization of Malignant Cells Expressing the T-Cell Receptor γδ von Farcet, Jean-Pierre, Gaulard, Philippe, Marolleau, Jean-Pierre, Couedic, Jean-Pierre Le, Henni, Tawfik, Gourdin, Marie-Francoise, Divine, Marine, Haioun, Corinne, Zafrani, Serge, Goossens, Michel, Hercend, Thierry, Reyes, Felix

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Missense Mutation of the Erythropoietin Receptor Is a Rare Event in Human Erythroid Malignancies von Couedic, Jean-Pierre Le, Mitjavila, Maria-Theresa, Villeval, Jean-Luc, Feger, Frédéric, Gobert, Stéphanie, Mayeux, Patrick, Casadevall, Nicole, Vainchenker, William

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Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily von Jandrot-Perrus, Martine, Busfield, Samantha, Lagrue, Anne-Helène, Xiong, Ximing, Debili, Najet, Chickering, Troy, Couedic, Jean-Pierre Le, Goodearl, Andrew, Dussault, Barry, Fraser, Christopher, Vainchenker, William, Villeval, Jean-Luc

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