FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential von Lay, Kenneth, Kume, Tsutomu, Fuchs, Elaine

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Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia von Robinson, Kim S., Teo, Daniel Eng Thiam, Tan, Kai Sen, Toh, Gee Ann, Ong, Hsiao Hui, Lim, Chrissie Kaishi, Lay, Kenneth, Au, Bijin Veonice, Lew, Tian Sheng, Chu, Justin Jang Hann, Chow, Vincent Tak Kwong, Wang, De Yun, Zhong, Franklin L., Reversade, Bruno

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In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators von Lien, Wen-Hui, Polak, Lisa, Lin, Mingyan, Lay, Kenneth, Zheng, Deyou, Fuchs, Elaine

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Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories von Gonzales, Kevin Andrew Uy, Polak, Lisa, Matos, Irina, Tierney, Matthew T., Gola, Anita, Wong, Ellen, Infarinato, Nicole R., Nikolova, Maria, Luo, Shijing, Liu, Siqi, Novak, Jesse S. S., Lay, Kenneth, Pasolli, Hilda Amalia, Fuchs, Elaine

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Modelling Human Hair Follicles-Lessons from Animal Models and Beyond von Tan, Chew Teng, Lim, Chin Yan, Lay, Kenneth

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Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8 von Gong, Qin, Robinson, Kim, Xu, Chenrui, Huynh, Phuong Thao, Chong, Kelvin Han Chung, Tan, Eddie Yong Jun, Zhang, Jiawen, Boo, Zhao Zhi, Teo, Daniel Eng Thiam, Lay, Kenneth, Zhang, Yaming, Lim, John Soon Yew, Goh, Wah Ing, Wright, Graham, Zhong, Franklin L., Reversade, Bruno, Wu, Bin

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Stem cells repurpose proliferation to contain a breach in their niche barrier von Lay, Kenneth, Yuan, Shaopeng, Gur-Cohen, Shiri, Miao, Yuxuan, Han, Tianxiao, Naik, Shruti, Pasolli, H Amalia, Larsen, Samantha B, Fuchs, Elaine

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Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by wh... von Tse, Hung-Fat, Ho, Jenny C Y, Choi, Shing-Wan, Lee, Yee-Ki, Butler, Amy W, Ng, Kwong-Man, Siu, Chung-Wah, Simpson, Michael A, Lai, Wing-Hon, Chan, Yau-Chi, Au, Ka-Wing, Zhang, Jinqiu, Lay, Kenneth W J, Esteban, Miguel A, Nicholls, John M, Colman, Alan, Sham, Pak C

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A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells von Fritz, Eric L, Rosenberg, Brad R, Lay, Kenneth, Mihailović, Aleksandra, Tuschl, Thomas, Papavasiliou, F Nina

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NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure von Eom, Taesun, Zhang, Chaolin, Wang, Huidong, Lay, Kenneth, Fak, John, Noebels, Jeffrey L, Darnell, Robert B

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Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by wh... von Tse, Hung-Fat, Ho, Jenny C. Y., Choi, Shing-Wan, Lee, Yee-Ki, Butler, Amy W., Ng, Kwong-Man, Siu, Chung-Wah, Simpson, Michael A., Lai, Wing-Hon, Chan, Yau-Chi, Au, Ka-Wing, Zhang, Jinqiu, Lay, Kenneth W. J., Esteban, Miguel A., Nicholls, John M., Colman, Alan, Sham, Pak C.

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Modeling of lamin A/C mutation premature cardiac aging using patient‐specific induced pluripotent stem cells von Siu, Chung-Wah, Lee, Yee-Ki, Ho, Jenny Chung-Yee, Lai, Wing-Hon, Chan, Yau-Chi, Ng, Kwong-Man, Wong, Lai-Yung, Au, Ka-Wing, Lau, Yee-Man, Zhang, Jinqiu, Lay, Kenneth Weijian, Colman, Alan, Tse, Hung-Fat

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Upregulating CXCR4 in Human Fetal Mesenchymal Stem Cells Enhances Engraftment and Bone Mechanics in a Mouse Model of Osteogenesis Imperfecta von Jones, Gemma N., Moschidou, Dafni, Lay, Kenneth, Abdulrazzak, Hassan, Vanleene, Maximilien, Shefelbine, Sandra J., Polak, Julia, de Coppi, Paolo, Fisk, Nicholas M., Guillot, Pascale V.

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Patient-specific induced-pluripotent stem cells derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by wh... von Tse, H.-F., Ho, J. C. Y., Choi, S.-W., Butler, A. W., Ng, K.-M., Siu, C.-W., Simpson, M. A., Lai, W.-H., Chan, Y.-C., Au, K.-W., Zhang, J., Lay, K. W. J., Esteban, M. A., Nicholls, J. M., Alan, C., Sham, P. C.

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Regulation of Expression of the Rat Orthologue of Mouse Double Minute 2 (MDM2) by H2O2-induced Oxidative Stress in Neonatal Rat Cardiac Myocytes von Pikkarainen, Sampsa, Kennedy, Robert A., Marshall, Andrew K., Tham, El Li, Lay, Kenneth, Kriz, Thomas A., Handa, Balvinder S., Clerk, Angela, Sugden, Peter H.

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Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells von Planès, Rémi, Pinilla, Miriam, Santoni, Karin, Hessel, Audrey, Passemar, Charlotte, Lay, Kenneth, Paillette, Perrine, Valadão, Ana-Luiza Chaves, Robinson, Kim Samirah, Bastard, Paul, Lam, Nathaniel, Fadrique, Ricardo, Rossi, Ida, Pericat, David, Bagayoko, Salimata, Leon-Icaza, Stephen Adonai, Rombouts, Yoann, Perouzel, Eric, Tiraby, Michèle, Zhang, Qian, Cicuta, Pietro, Jouanguy, Emmanuelle, Neyrolles, Olivier, Bryant, Clare E., Floto, Andres R., Goujon, Caroline, Lei, Franklin Zhong, Martin-Blondel, Guillaume, Silva, Stein, Casanova, Jean-Laurent, Cougoule, Céline, Reversade, Bruno, Marcoux, Julien, Ravet, Emmanuel, Meunier, Etienne

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The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death von Meijles, Daniel N., Zoumpoulidou, Georgia, Markou, Thomais, Rostron, Kerry A., Patel, Rishi, Lay, Kenneth, Handa, Balvinder S., Wong, Bethany, Sugden, Peter H., Clerk, Angela

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Valproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach von Moschidou, Dafni, Mukherjee, Sayandip, Blundell, Michael P., Drews, Katharina, Jones, Gemma N., Abdulrazzak, Hassan, Nowakowska, Beata, Phoolchund, Anju, Lay, Kenneth, Ramasamy, T Selvee, Cananzi, Mara, Nettersheim, Daniel, Sullivan, Mark, Frost, Jennifer, Moore, Gudrun, Vermeesch, Joris R., Fisk, Nicholas M., Thrasher, Adrian J., Atala, Anthony, Adjaye, James, Schorle, Hubert, De Coppi, Paolo, Guillot, Pascale V.

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Valproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach von Moschidou, Dafni, Mukherjee, Sayandip, Blundell, Michael P, Drews, Katharina, Jones, Gemma N, Abdulrazzak, Hassan, Nowakowska, Beata, Phoolchund, Anju, Lay, Kenneth, Ramasamy, T Selvee, Cananzi, Mara, Nettersheim, Daniel, Sullivan, Mark, Frost, Jennifer, Moore, Gudrun, Vermeesch, Joris R, Fisk, Nicholas M, Thrasher, Adrian J, Atala, Anthony, Adjaye, James, Schorle, Hubert, De Coppi, Paolo, Guillot, Pascale V

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Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis von Moreno Traspas, Ricardo, Teoh, Tze Shin, Wong, Pui-Mun, Maier, Michael, Chia, Crystal Y., Lay, Kenneth, Ali, Nur Ain, Larson, Austin, Al Mutairi, Fuad, Al-Sannaa, Nouriya Abbas, Faqeih, Eissa Ali, Alfadhel, Majid, Cheema, Huma Arshad, Dupont, Juliette, Bézieau, Stéphane, Isidor, Bertrand, Low, Dorrain Yanwen, Wang, Yulan, Tan, Grace, Lai, Poh San, Piloquet, Hugues, Joubert, Madeleine, Kayserili, Hulya, Kripps, Kimberly A., Nahas, Shareef A., Wartchow, Eric P., Warren, Mikako, Bhavani, Gandham SriLakshmi, Dasouki, Majed, Sandoval, Renata, Carvalho, Elisa, Ramos, Luiza, Porta, Gilda, Wu, Bin, Lashkari, Harsha Prasada, AlSaleem, Badr, BaAbbad, Raeda M., Abreu Ferrão, Anabela Natália, Karageorgou, Vasiliki, Ordonez-Herrera, Natalia, Khan, Suliman, Bauer, Peter, Cogne, Benjamin, Bertoli-Avella, Aida M., Vincent, Marie, Girisha, Katta Mohan, Reversade, Bruno

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