Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing von Zamò, A, Pischimarov, J, Schlesner, M, Rosenstiel, P, Bomben, R, Horn, H, Grieb, T, Nedeva, T, López, C, Haake, A, Richter, J, Trümper, L, Lawerenz, C, Klapper, W, Möller, P, Hummel, M, Lenze, D, Szczepanowski, M, Flossbach, L, Schreder, M, Gattei, V, Ott, G, Siebert, R, Rosenwald, A, Leich, E

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MUTATIONAL SIGNATURES IN GERMINAL CENTER DERIVED B‐CELL LYMPHOMAS FROM ADULT PATIENTS ANALYZED IN THE ICGC MMML‐SEQ CONSORTIUM von Huebschmann, D., Kleinheinz, K., Wagener, R., Kretzmer, H., Toprak, U.H., Bernhart, S.H., Lopez Gonzales, C., Kreuz, M., Eils, R., Hansmann, M., Hoffmann, S., Hummel, M., Klapper, W., Lawerenz, C., Loeffler, M., Möller, P., Richter, J., Rosenstiel, P., Rosenwald, A., Stilgenbauer, S., Weniger, M., Trümper, L., Küppers, R., Schlesner, M., Siebert, R.

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Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort von Waszak, SM, Northcott, PA, Buchhalter, I, Robinson, GW, Sutter, C, Groebner, S, Grund, KB, Brugières, L, Jones, DTW, Pajtler, KW, Morrissy, AS, Kool, M, Sturm, D, Chavez, L, Ernst, A, Brabetz, S, Hain, M, Zichner, T, Segura-Wang, M, Weischenfeldt, J, Rausch, T, Mardin, BR, Zhou, X, Baciu, C, Lawerenz, C, Chan, JA, Varlet, P, Guerrini-Rousseau, L, Fults, DW, Grajkowska, W, Hauser, P, Jabado, N, Ra, YS, Zitterbart, K, Shringarpure, SS, De La Vega, FM, Bustamante, CD, Ng, HK, Perry, A, MacDonald, TJ, Hernáiz Driever, P, Bendel, AE, Bowers, DC, McCowage, G, Chintagumpala, MM, Cohn, R, Hassall, T, Fleischhack, G, Eggen, T, Wesenberg, F, Feychting, M, Lannering, B, Schüz, J, Johansen, C, Andersen, TV, Röösli, M, Kuehni, CE, Grotzer, M, Kjaerheim, K, Monoranu, CM, Archer, TC, Duke, E, Pomeroy, SL, Shelagh, R, Frank, S, Sumerauer, D, Scheurlen, W, Ryzhova, MV, Milde, T, Kratz, CP, Samuel, D, Zhang, J, Solomon, DA, Marra, M, Eils, R, Bartram, CR, von Hoff, K, Rutkowski, S, Ramaswamy, V, Gilbertson, RJ, Korshunov, A, Taylor, MD, Lichter, P, Malkin, D, Gajjar, A, Korbel, JO, Pfister, SM

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The landscape of genomic alterations across childhood cancers von Gröbner, Susanne N., Worst, Barbara C., Weischenfeldt, Joachim, Buchhalter, Ivo, Kleinheinz, Kortine, Rudneva, Vasilisa A., Johann, Pascal D., Balasubramanian, Gnana Prakash, Segura-Wang, Maia, Brabetz, Sebastian, Bender, Sebastian, Hutter, Barbara, Sturm, Dominik, Pfaff, Elke, Hübschmann, Daniel, Zipprich, Gideon, Heinold, Michael, Eils, Jürgen, Lawerenz, Christian, Erkek, Serap, Lambo, Sander, Waszak, Sebastian, Blattmann, Claudia, Borkhardt, Arndt, Kuhlen, Michaela, Eggert, Angelika, Fulda, Simone, Gessler, Manfred, Wegert, Jenny, Kappler, Roland, Baumhoer, Daniel, Burdach, Stefan, Kirschner-Schwabe, Renate, Kontny, Udo, Kulozik, Andreas E., Lohmann, Dietmar, Hettmer, Simone, Eckert, Cornelia, Bielack, Stefan, Nathrath, Michaela, Niemeyer, Charlotte, Richter, Günther H., Schulte, Johannes, Siebert, Reiner, Westermann, Frank, Molenaar, Jan J., Vassal, Gilles, Witt, Hendrik, Burkhardt, Birgit, Kratz, Christian P., Witt, Olaf, van Tilburg, Cornelis M., Kramm, Christof M., Fleischhack, Gudrun, Dirksen, Uta, Rutkowski, Stefan, Frühwald, Michael, von Hoff, Katja, Wolf, Stephan, Klingebiel, Thomas, Koscielniak, Ewa, Landgraf, Pablo, Koster, Jan, Resnick, Adam C., Zhang, Jinghui, Liu, Yanling, Zhou, Xin, Waanders, Angela J., Zwijnenburg, Danny A., Raman, Pichai, Brors, Benedikt, Weber, Ursula D., Northcott, Paul A., Pajtler, Kristian W., Kool, Marcel, Piro, Rosario M., Korbel, Jan O., Schlesner, Matthias, Eils, Roland, Jones, David T. W., Lichter, Peter, Chavez, Lukas, Zapatka, Marc, Pfister, Stefan M.

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Mitochondrial mutations drive prostate cancer aggression von Hopkins, Julia F., Sabelnykova, Veronica Y., Weischenfeldt, Joachim, Simon, Ronald, Aguiar, Jennifer A., Alkallas, Rached, Heisler, Lawrence E., Zhang, Junyan, Watson, John D., Chua, Melvin L. K., Fraser, Michael, Favero, Francesco, Lawerenz, Chris, Plass, Christoph, Sauter, Guido, McPherson, John D., van der Kwast, Theodorus, Korbel, Jan, Schlomm, Thorsten, Bristow, Robert G., Boutros, Paul C.

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Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteri... von Bielack, S S, Cox, M C, Nathrath, M, Apel, K, Blattmann, C, Holl, T, Jenewein, R, Klenk, U, Klothaki, P, Müller-Abt, P, Ortega-Lawerenz, S, Reynolds, M, Scheer, M, Simon-Klingenstein, K, Stegmaier, S, Tupper, R, Vokuhl, C, von Kalle, T

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Signatures of mutational processes in human cancer von Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Aparicio, Samuel A. J. R., Behjati, Sam, Biankin, Andrew V., Bignell, Graham R., Bolli, Niccolò, Borg, Ake, Børresen-Dale, Anne-Lise, Boyault, Sandrine, Burkhardt, Birgit, Butler, Adam P., Caldas, Carlos, Davies, Helen R., Desmedt, Christine, Eils, Roland, Eyfjörd, Jórunn Erla, Foekens, John A., Greaves, Mel, Hosoda, Fumie, Hutter, Barbara, Ilicic, Tomislav, Imbeaud, Sandrine, Imielinski, Marcin, Jäger, Natalie, Jones, David T. W., Jones, David, Knappskog, Stian, Kool, Marcel, Lakhani, Sunil R., López-Otín, Carlos, Martin, Sancha, Munshi, Nikhil C., Nakamura, Hiromi, Northcott, Paul A., Pajic, Marina, Papaemmanuil, Elli, Paradiso, Angelo, Pearson, John V., Puente, Xose S., Raine, Keiran, Ramakrishna, Manasa, Richardson, Andrea L., Richter, Julia, Rosenstiel, Philip, Schlesner, Matthias, Schumacher, Ton N., Span, Paul N., Teague, Jon W., Totoki, Yasushi, Tutt, Andrew N. J., Valdés-Mas, Rafael, van Buuren, Marit M., van ’t Veer, Laura, Vincent-Salomon, Anne, Waddell, Nicola, Yates, Lucy R., Zucman-Rossi, Jessica, Andrew Futreal, P., McDermott, Ultan, Lichter, Peter, Meyerson, Matthew, Grimmond, Sean M., Siebert, Reiner, Campo, Elías, Shibata, Tatsuhiro, Pfister, Stefan M., Campbell, Peter J., Stratton, Michael R.

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Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories von Gerhauser, Clarissa, Favero, Francesco, Risch, Thomas, Simon, Ronald, Feuerbach, Lars, Assenov, Yassen, Heckmann, Doreen, Sidiropoulos, Nikos, Waszak, Sebastian M., Hübschmann, Daniel, Urbanucci, Alfonso, Girma, Etsehiwot G., Kuryshev, Vladimir, Klimczak, Leszek J., Saini, Natalie, Stütz, Adrian M., Weichenhan, Dieter, Böttcher, Lisa-Marie, Toth, Reka, Hendriksen, Josephine D., Koop, Christina, Lutsik, Pavlo, Matzk, Sören, Warnatz, Hans-Jörg, Amstislavskiy, Vyacheslav, Feuerstein, Clarissa, Raeder, Benjamin, Bogatyrova, Olga, Schmitz, Eva-Maria, Hube-Magg, Claudia, Kluth, Martina, Huland, Hartwig, Graefen, Markus, Lawerenz, Chris, Henry, Gervaise H., Yamaguchi, Takafumi N., Malewska, Alicia, Meiners, Jan, Schilling, Daniela, Reisinger, Eva, Eils, Roland, Schlesner, Matthias, Strand, Douglas W., Bristow, Robert G., Boutros, Paul C., von Kalle, Christof, Gordenin, Dmitry, Sültmann, Holger, Brors, Benedikt, Sauter, Guido, Plass, Christoph, Yaspo, Marie-Laure, Korbel, Jan O., Schlomm, Thorsten, Weischenfeldt, Joachim

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Recurrent MET fusion genes represent a drug target in pediatric glioblastoma von Bender, Sebastian, Gronych, Jan, Warnatz, Hans-Jorg, Hutter, Barbara, Grobner, Susanne, Ryzhova, Marina, Pfaff, Elke, Hovestadt, Volker, Weinberg, Florian, Halbach, Sebastian, Kool, Marcel, Northcott, Paul A, Sturm, Dominik, Bjerke, Lynn, Zichner, Thomas, Stuetz, Adrian M, Schramm, Kathrin, Huang, Bingding, Buchhalter, Ivo, Heinold, Michael, Risch, Thomas, Worst, Barbara C, van Tilburg, Cornelis M, Weber, Ursula D, Zapatka, Marc, Raeder, Benjamin, Milford, David, Heiland, Sabine, von Kalle, Christof, Previti, Christopher, Lawerenz, Chris, Kulozik, Andreas E, Unterberg, Andreas, Witt, Olaf, von Deimling, Andreas, Capper, David, Truffaux, Nathalene, Grill, Jacques, Jabado, Nada, Sehested, Astrid M, Sumerauer, David, Brahim, Dorra Hmida-Ben, Trabelsi, Saoussen, Ng, Ho-Keung, Zagzag, David, Allen, Jeffrey C, Karajannis, Matthias A, Gottardo, Nicholas G, Jones, Chris, Korbel, Jan O, et. al

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Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer von Weischenfeldt, Joachim, Simon, Ronald, Feuerbach, Lars, Schlangen, Karin, Weichenhan, Dieter, Minner, Sarah, Wuttig, Daniela, Warnatz, Hans-Jörg, Stehr, Henning, Rausch, Tobias, Jäger, Natalie, Gu, Lei, Bogatyrova, Olga, Stütz, Adrian M., Claus, Rainer, Eils, Jürgen, Eils, Roland, Gerhäuser, Clarissa, Huang, Po-Hsien, Hutter, Barbara, Kabbe, Rolf, Lawerenz, Christian, Radomski, Sylwester, Bartholomae, Cynthia C., Fälth, Maria, Gade, Stephan, Schmidt, Manfred, Amschler, Nina, Haß, Thomas, Galal, Rami, Gjoni, Jovisa, Kuner, Ruprecht, Baer, Constance, Masser, Sawinee, von Kalle, Christof, Zichner, Thomas, Benes, Vladimir, Raeder, Benjamin, Mader, Malte, Amstislavskiy, Vyacheslav, Avci, Meryem, Lehrach, Hans, Parkhomchuk, Dmitri, Sultan, Marc, Burkhardt, Lia, Graefen, Markus, Huland, Hartwig, Kluth, Martina, Krohn, Antje, Sirma, Hüseyin, Stumm, Laura, Steurer, Stefan, Grupp, Katharina, Sültmann, Holger, Sauter, Guido, Plass, Christoph, Brors, Benedikt, Yaspo, Marie-Laure, Korbel, Jan O., Schlomm, Thorsten

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Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing von RICHTER, Julia, SCHLESNER, Matthias, LENZE, Dido, SZCZEPANOWSKI, Monika, PAULSEN, Maren, LIPINSKI, Simone, RUSSELL, Robert B, ADAM-KLAGES, Sabine, APIC, Gordana, CLAVIEZ, Alexander, HASENCLEVER, Dirk, HOVESTADT, Volker, HOFFMANN, Steve, HORNIG, Nadine, KORBEL, Jan O, KUBE, Dieter, LANGENBERGER, David, LAWERENZ, Chris, LISFELD, Jasmin, MEYER, Katharina, PICELLI, Simone, PISCHIMAROV, Jordan, RADLWIMMER, Bernhard, KREUZ, Markus, RAUSCH, Tobias, ROHDE, Marius, SCHILHABEL, Markus, SCHOLTYSIK, René, SPANG, Rainer, TRAUTMANN, Heiko, ZENZ, Thorsten, BORKHARDT, Arndt, DREXLER, Hans G, MÖLLER, Peter, LEICH, Ellen, MACLEOD, Roderick A. F, POTT, Christiane, SCHREIBER, Stefan, TRÜMPER, Lorenz, LOEFFLER, Markus, STADLER, Peter F, LICHTER, Peter, EILS, Roland, KÜPPERS, Ralf, HUMMEL, Michael, BURKHARDT, Birgit, KLAPPER, Wolfram, ROSENSTIEL, Philip, ROSENWALD, Andreas, BRORS, Benedikt, SIEBERT, Reiner, ROSOLOWSKI, Maciej, AMMERPOHL, Ole, WAGENER, Rabea, BERNHART, Stephan H

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Author Correction: The landscape of genomic alterations across childhood cancers von Gröbner, Susanne N., Worst, Barbara C., Weischenfeldt, Joachim, Buchhalter, Ivo, Kleinheinz, Kortine, Rudneva, Vasilisa A., Johann, Pascal D., Balasubramanian, Gnana Prakash, Segura-Wang, Maia, Brabetz, Sebastian, Bender, Sebastian, Hutter, Barbara, Sturm, Dominik, Pfaff, Elke, Hübschmann, Daniel, Zipprich, Gideon, Heinold, Michael, Eils, Jürgen, Lawerenz, Christian, Erkek, Serap, Lambo, Sander, Waszak, Sebastian, Blattmann, Claudia, Borkhardt, Arndt, Kuhlen, Michaela, Eggert, Angelika, Fulda, Simone, Gessler, Manfred, Wegert, Jenny, Kappler, Roland, Baumhoer, Daniel, Burdach, Stefan, Kirschner-Schwabe, Renate, Kontny, Udo, Kulozik, Andreas E., Lohmann, Dietmar, Hettmer, Simone, Eckert, Cornelia, Bielack, Stefan, Nathrath, Michaela, Niemeyer, Charlotte, Richter, Günther H., Schulte, Johannes, Siebert, Reiner, Westermann, Frank, Molenaar, Jan J., Vassal, Gilles, Witt, Hendrik, Burkhardt, Birgit, Kratz, Christian P., Witt, Olaf, van Tilburg, Cornelis M., Kramm, Christof M., Fleischhack, Gudrun, Dirksen, Uta, Rutkowski, Stefan, Frühwald, Michael, von Hoff, Katja, Wolf, Stephan, Klingebiel, Thomas, Koscielniak, Ewa, Landgraf, Pablo, Koster, Jan, Resnick, Adam C., Zhang, Jinghui, Liu, Yanling, Zhou, Xin, Waanders, Angela J., Zwijnenburg, Danny A., Raman, Pichai, Brors, Benedikt, Weber, Ursula D., Northcott, Paul A., Pajtler, Kristian W., Kool, Marcel, Piro, Rosario M., Korbel, Jan O., Schlesner, Matthias, Eils, Roland, Jones, David T. W., Lichter, Peter, Chavez, Lukas, Zapatka, Marc, Pfister, Stefan M.

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Publisher Correction: Butler enables rapid cloud-based analysis of thousands of human genomes von Yakneen, Sergei, Waszak, Sebastian M., Gertz, Michael, Korbel, Jan O.

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Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes von Yakneen, Sergei, Waszak, Sebastian M., Gertz, Michael, Korbel, Jan O.

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Butler enables rapid cloud-based analysis of thousands of human genomes von Yakneen, Sergei, Waszak, Sebastian M., Gertz, Michael, Korbel, Jan O.

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Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis von Hezaveh, Kebria, Kloetgen, Andreas, Bernhart, Stephan H, Mahapatra, Kunal Das, Lenze, Dido, Richter, Julia, Haake, Andrea, Bergmann, Anke K, Brors, Benedikt, Burkhardt, Birgit, Claviez, Alexander, Drexler, Hans G, Eils, Roland, Haas, Siegfried, Hoffmann, Steve, Karsch, Dennis, Klapper, Wolfram, Kleinheinz, Kortine, Korbel, Jan, Kretzmer, Helene, Kreuz, Markus, Küppers, Ralf, Lawerenz, Chris, Leich, Ellen, Loeffler, Markus, Mantovani-Loeffler, Luisa, López, Cristina, McHardy, Alice C, Möller, Peter, Rohde, Marius, Rosenstiel, Philip, Rosenwald, Andreas, Schilhabel, Markus, Schlesner, Matthias, Scholz, Ingrid, Stadler, Peter F, Stilgenbauer, Stephan, Sungalee, Stéphanie, Szczepanowski, Monika, Trümper, Lorenz, Weniger, Marc A, Siebert, Reiner, Borkhardt, Arndt, Hummel, Michael, Hoell, Jessica I

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Recurrent MET fusion genes represent a drug target in pediatric glioblastoma von Weinberg, Florian, Pfaff, Elke, Brors, Benedikt, Schmidt, Sabine, Reifenberger, Guido, Ryzhova, Marina, Trabelsi, Saoussen, Heinold, Michael, Eils, Roland, Brahim, Dorra Hmida-Ben, Lehrach, Hans, Sturm, Dominik, Allen, Jeffrey C, Felsberg, Jörg, Weber, Ursula D, Milford, David, Korbel, Jan O, Halbach, Sebastian, Lawerenz, Chris, Bender, Sebastian, Stütz, Adrian M, Kulozik, Andreas E, Hutter, Barbara, Gronych, Jan, Sumerauer, David, Karajannis, Matthias A, Buchhalter, Ivo, Jabado, Nada, Korshunov, Andrey, Gottardo, Nicholas G, Herold-Mende, Christel, Huang, Bingding, Bjerke, Lynn, Pfister, Stefan M, von Deimling, Andreas, Gröbner, Susanne, Raeder, Benjamin, Wolf, Stephan, Previti, Christopher, Unterberg, Andreas, Sehested, Astrid M, Brummer, Tilman, Warnatz, Hans-Jörg, Zichner, Thomas, Jones, Chris, Ng, Ho-Keung, Truffaux, Nathalène, Hovestadt, Volker, Risch, Thomas, Capper, David, Northcott, Paul A, Lichter, Peter, von Kalle, Christof, van Tilburg, Cornelis M, Jones, David T W, Heiland, Sabine, Schramm, Kathrin, Worst, Barbara C, Yaspo, Marie-Laure, Zapatka, Marc, Witt, Olaf, Zagzag, David, Kool, Marcel, Grill, Jacques

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Butler enables rapid cloud-based analysis of thousands of human genomes von Yakneen, Sergei, Waszak, Sebastian M, Gertz, Michael, Korbel, Jan O, Aminou, Brice, Bartolome, Javier, Boroevich, Keith A, Boyce, Rich, Brooks, Angela N, Buchanan, Alex, Buchhalter, Ivo, Butler, Adam P, Byrne, Niall J, Cafferkey, Andy, Campbell, Peter J, Chen, Zhaohong, Cho, Sunghoon, Choi, Wan, Clapham, Peter, Davis-Dusenbery, Brandi N, De La Vega, Francisco M, Demeulemeester, Jonas, Dow, Michelle T, Dursi, Lewis Jonathan, Eils, Juergen, Eils, Roland, Ellrott, Kyle, Farcas, Claudiu, Favero, Francesco, Fayzullaev, Nodirjon, Ferretti, Vincent, Flicek, Paul, Fonseca, Nuno A, Gelpi, Josep Ll, Getz, Gad, Gibson, Bob, Grossman, Robert L, Harismendy, Olivier, Heath, Allison P, Heinold, Michael C, Hess, Julian M, Hofmann, Oliver, Hong, Jongwhi H, Hudson, Thomas J, Hutter, Barbara, Hutter, Carolyn M, Huebschmann, Daniel, Imoto, Seiya, Ivkovic, Sinisa, Jeon, Seung-Hyup, Jiao, Wei, Jung, Jongsun, Kabbe, Rolf, Kahles, Andre, Kerssemakers, Jules N.A, Kim, Hyung-Lae, Kim, Hyunghwan, Kim, Jihoon, Kim, Youngwook, Kleinheinz, Kortine, Koscher, Michael, Koures, Antonios, Kovacevic, Milena, Lawerenz, Chris, Leshchiner, Ignaty, Liu, Jia, Livitz, Dimitri, Mihaiescu, George L, Mijalkovic, Sanja, Lazic, Ana Mijalkovic, Miyano, Satoru, Miyoshi, Naoki, Nahal-Bose, Hardeep K, Nakagawa, Hidewaki, Nastic, Mia, Newhouse, Steven J, Nicholson, Jonathan, O'Connor, Brian D, Ocana, David, Ohi, Kazuhiro, Ohno-Machado, Lucila, Omberg, Larsson, Ouellette, B.F. Francis, Paramasivam, Nagarajan, Perry, Marc D, Pihl, Todd D, Prinz, Manuel, Puiggros, Montserrat, Radovic, Petar, Raine, Keiran M, Rheinbay, Esther, Rosenberg, Mara, Royo, Romina, Raetsch, Gunnar, Saksena, Gordon, Schlesner, Matthias, Shorser, Solomon, Short, Charles, Sofia, Heidi J, Spring, Jonathan

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The PCBP1 gene encoding poly(rc) binding protein i is recurrently mutated in Burkitt lymphoma von Wagener, Rabea, Aukema, Sietse M., Schlesner, Matthias, Haake, Andrea, Burkhardt, Birgit, Claviez, Alexander, Drexler, Hans G., Hummel, Michael, Kreuz, Markus, Loeffler, Markus, Rosolowski, Maciej, López, Cristina, Möller, Peter, Richter, Julia, Rohde, Marius, Betts, Matthew J., Russell, Robert B., Bernhart, Stephan H., Hoffmann, Steve, Rosenstiel, Philip, Schilhabel, Markus, Szczepanowski, Monika, Trümper, Lorenz, Klapper, Wolfram, Siebert, Reiner

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On the Trade-Off between Industrially Feasible Silicon Surface Preconditioning Prior to Interface Passivation and Iron Contaminant Removal Effectiveness von Sperlich, Hans Peter, Möller, Christian, Laades, Abdelazize, Lauer, Kevin, Stürzebecher, Uta, Lawerenz, Alexander

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