The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (M... von Ericson, Mark D, Freeman, Katie T, LaVoi, Travis M, Donow, Haley M, Santos, Radleigh G, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Haskell-Luevano, Carrie

Volltext

Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin‑4 Receptor and Equipotent wi... von Ericson, Mark D, Doering, Skye R, Larson, Courtney M, Freeman, Katie T, LaVoi, Travis M, Donow, Haley M, Santos, Radleigh G, Cho, Rachel H, Koerperich, Zoe M, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Haskell-Luevano, Carrie

Volltext

Combinatorial Libraries As a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens von Fleeman, Renee, LaVoi, Travis M, Santos, Radleigh G, Morales, Angela, Nefzi, Adel, Welmaker, Gregory S, Medina-Franco, José L, Giulianotti, Marc A, Houghten, Richard A, Shaw, Lindsey N

Volltext

Correction to “Discovery of Nanomolar Melanocortin‑3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput ‘Unbiased’ Sc... von Doering, Skye R., Freeman, Katie, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G., Lavoi, Travis M., Giulianotti, Marc A., Pinilla, Clemencia, Appel, Jon R., Houghten, Richard A., Ericson, Mark D., Haskell-Luevano, Carrie

Volltext

Discovery of Nanomolar Melanocortin‑3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput “Unbiased” Screening Campaig... von Doering, Skye R, Freeman, Katie, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G, Lavoi, Travis M, Giulianotti, Marc A, Pinilla, Clemencia, Appel, Jon R, Houghten, Richard A, Ericson, Mark D, Haskell-Luevano, Carrie

Volltext

SAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro Probes von Knapinska, Anna M, Dreymuller, Daniela, Ludwig, Andreas, Smith, Lyndsay, Golubkov, Vladislav, Sohail, Anjum, Fridman, Rafael, Giulianotti, Marc, LaVoi, Travis M, Houghten, Richard A, Fields, Gregg B, Minond, Dmitriy

Volltext

Scaffold Ranking and Positional Scanning Utilized in the Discovery of nAChR-Selective Compounds Suitable for Optimization Studies von Wu, Jinhua, Zhang, Yaohong, Maida, Laura E, Santos, Radleigh G, Welmaker, Gregory S, LaVoi, Travis M, Nefzi, Adel, Yu, Yongping, Houghten, Richard A, Toll, Lawrence, Giulianotti, Marc A

Volltext

SAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A D isintegrin A nd M etalloprotease 17 (ADAM17) and Application as Selective in Vitro Probes von Knapinska, Anna M., Dreymuller, Daniela, Ludwig, Andreas, Smith, Lyndsay, Golubkov, Vladislav, Sohail, Anjum, Fridman, Rafael, Giulianotti, Marc, LaVoi, Travis M., Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy

Volltext

A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery von Palrasu, Manikandan, Knapinska, Anna M, Diez, Juan, Smith, Lyndsay, LaVoi, Travis, Giulianotti, Marc, Houghten, Richard A, Fields, Gregg B, Minond, Dmitriy

Volltext

Structure-Activity Relationship of Pyrrolidine Pentamine Derivatives as Inhibitors of the Aminoglycoside 6'- N -Acetyltransferase Type Ib von Sklenicka, Jan, Tran, Tung, Ramirez, Maria S, Donow, Haley M, Magaña, Angel J, LaVoi, Travis, Mamun, Yasir, Jimenez, Verónica, Chapagain, Prem, Santos, Radleigh, Pinilla, Clemencia, Giulianotti, Marc A, Tolmasky, Marcelo E

Volltext