A new target for fetal hemoglobin reactivation von Rivers, Angela, Molokie, Robert, Lavelle, Donald

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Effect of the LSD1 inhibitor RN-1 on γ-globin and global gene expression during erythroid differentiation in baboons (Papio anubis) von Ibanez, Vinzon, Vaitkus, Kestis, Ruiz, Maria Armila, Lei, Zhengdeng, Maienschein-Cline, Mark, Arbieva, Zarema, Lavelle, Donald

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Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study von Molokie, Robert, Lavelle, Donald, Gowhari, Michel, Pacini, Michael, Krauz, Lani, Hassan, Johara, Ibanez, Vinzon, Ruiz, Maria A, Ng, Kwok Peng, Woost, Philip, Radivoyevitch, Tomas, Pacelli, Daisy, Fada, Sherry, Rump, Matthew, Hsieh, Matthew, Tisdale, John F, Jacobberger, James, Phelps, Mitch, Engel, James Douglas, Saraf, Santhosh, Hsu, Lewis L, Gordeuk, Victor, DeSimone, Joseph, Saunthararajah, Yogen

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The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice von Cui, Shuaiying, Lim, Kim-Chew, Shi, Lihong, Lee, Mary, Jearawiriyapaisarn, Natee, Myers, Greggory, Campbell, Andrew, Harro, David, Iwase, Shigeki, Trievel, Raymond C., Rivers, Angela, DeSimone, Joseph, Lavelle, Donald, Saunthararajah, Yogen, Engel, James Douglas

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The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis) von Rivers, Angela, Vaitkus, Kestis, Ibanez, Vinzon, Ruiz, Maria Armila, Jagadeeswaran, Ramasamy, Saunthararajah, Yogen, Cui, Shuaiying, Engel, James D, DeSimone, Joseph, Lavelle, Donald

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Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons von Ibanez, Vinzon, Vaitkus, Kestis, Rivers, Angela, Molokie, Robert, Cui, Shuaiying, Engel, James Douglas, DeSimone, Joseph, Lavelle, Donald

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Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine von Lavelle, Donald, Vaitkus, Kestis, Ling, Yonghua, Ruiz, Maria A., Mahfouz, Reda, Ng, Kwok Peng, Negrotto, Soledad, Smith, Nicola, Terse, Pramod, Engelke, Kory J., Covey, Joseph, Chan, Kenneth K., DeSimone, Joseph, Saunthararajah, Yogen

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Pharmacological Therapies Targeting Epigenetic Regulatory Mechanisms for Sickle Cell Disease and ?-thalassemia von Lavelle, Donald

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Pharmacological Therapies Targeting Epigenetic Regulatory Mechanisms for Sickle Cell Disease and B-thalassemia von Donald Lavelle

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Pharmacological Therapies Targeting Epigenetic Regulatory Mechanisms for Sickle Cell Disease and B-thalassemia von Donald Lavelle

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Pharmacological Therapies Targeting Epigenetic Regulatory Mechanisms for Sickle Cell Disease and B-thalassemia von Donald Lavelle

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Modification of hematopoietic stem cell fate by 5aza 2′deoxycytidine and trichostatin A von Milhem, Mohammed, Mahmud, Nadim, Lavelle, Donald, Araki, Hiroto, DeSimone, Joseph, Saunthararajah, Yogen, Hoffman, Ronald

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The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with β-Hemoglobin Disorders von Chambers, Christopher B., Gross, Jeffrey, Pratt, Katherine, Guo, Xiang, Byrnes, Colleen, Lee, Y. Terry, Lavelle, Donald, Dean, Ann, Miller, Jeffery L., Wilber, Andrew

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Clinical effectiveness of decitabine in severe sickle cell disease von Saunthararajah, Yogen, Molokie, Robert, Saraf, Santosh, Sidhwani, Seema, Gowhari, Michel, Vara, Steven, Lavelle, Donald, DeSimone, Joseph

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Fetal Hemoglobin Induction by Epigenetic Drugs von Lavelle, Donald, Engel, James Douglas, Saunthararajah, Yogen

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Effect of the Oral LSD1 Inhibitor Ory-1001 on F-Retics in Baboons ( Papio anubis) von Ibanez, Vinzon, Vaitkus, Kestis, Molokie, Robert, Saunthararajah, Yogenthiran, Lavelle, Donald

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Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia von DeSimone, Joseph, Koshy, Mabel, Dorn, Louise, Lavelle, Donald, Bressler, Linda, Molokie, Robert, Talischy, Nasrin

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Effect of AGM and fetal liver-derived stromal cell lines on globin expression in adult baboon (P. anubis) bone marrow-derived erythroid progenitors von Lavelle, Donald, Vaitkus, Kestutis, Ruiz, Maria Armila, Ibanez, Vinzon, Kouznetsova, Tatiana, Saunthararajah, Yogen, Mahmud, Nadim, DeSimone, Joseph

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The molecular mechanism of fetal hemoglobin reactivation von Lavelle, Donald E.

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2-deoxy 5-azacytidine and fetal hemoglobin induction in sickle cell anemia von Koshy, Mabel, Dorn, Louise, Bressler, Linda, Molokie, Robert, Lavelle, Donald, Talischy, Nasrin, Hoffman, Ronald, van Overveld, Wendy, DeSimone, Joseph

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