Senescence drives immunotherapy resistance by inducing an immunosuppressive tumor microenvironment von Maggiorani, Damien, Le, Oanh, Lisi, Véronique, Landais, Séverine, Moquin-Beaudry, Gaël, Lavallée, Vincent Philippe, Decaluwe, Hélène, Beauséjour, Christian

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Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity von Brown, Chrysothemis C., Gudjonson, Herman, Pritykin, Yuri, Deep, Deeksha, Lavallée, Vincent-Philippe, Mendoza, Alejandra, Fromme, Rachel, Mazutis, Linas, Ariyan, Charlotte, Leslie, Christina, Pe’er, Dana, Rudensky, Alexander Y.

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Regenerative lineages and immune-mediated pruning in lung cancer metastasis von Laughney, Ashley M., Hu, Jing, Campbell, Nathaniel R., Bakhoum, Samuel F., Setty, Manu, Lavallée, Vincent-Philippe, Xie, Yubin, Masilionis, Ignas, Carr, Ambrose J., Kottapalli, Sanjay, Allaj, Viola, Mattar, Marissa, Rekhtman, Natasha, Xavier, Joao B., Mazutis, Linas, Poirier, John T., Rudin, Charles M., Pe’er, Dana, Massagué, Joan

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Therapeutic Inducers of Natural Killer cell Killing (ThINKK): preclinical assessment of safety and efficacy in allogeneic hematopoietic stem cell transplant settings von Poirier, Nicolas, Paquin, Valérie, Leclerc, Séverine, Lisi, Véronique, Marmolejo, Carolina, Affia, Hicham, Cordeiro, Paulo, Théorêt, Yves, Haddad, Elie, Andelfinger, Gregor, Lavallée, Vincent Philippe, Duval, Michel, Herblot, Sabine

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Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia von McNeer, Nicole A., Philip, John, Geiger, Heather, Ries, Rhonda E., Lavallée, Vincent-Philippe, Walsh, Michael, Shah, Minita, Arora, Kanika, Emde, Anne-Katrin, Robine, Nicolas, Alonzo, Todd A., Kolb, E. Anders, Gamis, Alan S., Smith, Malcolm, Gerhard, Daniela Se, Guidry-Auvil, Jaime, Meshinchi, Soheil, Kentsis, Alex

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Genetic characterization of ABT-199 sensitivity in human AML von Bisaillon, Richard, Moison, Céline, Thiollier, Clarisse, Krosl, Jana, Bordeleau, Marie-Eve, Lehnertz, Bernhard, Lavallée, Vincent-Philippe, MacRae, Tara, Mayotte, Nadine, Labelle, Caroline, Boucher, Geneviève, Spinella, Jean-François, Boivin, Isabel, D’Angelo, Giovanni, Lavallée, Sylvie, Marinier, Anne, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy

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Pediatric acute promyelocytic leukemia and Fanconi anemia: Case report and literature review von Freycon, Claire, Sepulchre, Edith, Lavallée, Vincent‐Philippe, Mitchell, David, MacMillan, Margaret L., Vezina, Catherine, Goudie, Catherine

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CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216 von Gress, Verena, Roussy, Mathieu, Boulianne, Luc, Bilodeau, Mélanie, Cardin, Sophie, El-Hachem, Nehme, Lisi, Véronique, Khakipoor, Banafsheh, Rouette, Alexandre, Farah, Azer, Théret, Louis, Aubert, Léo, Fatima, Furat, Audemard, Éric, Thibault, Pierre, Bonneil, Éric, Chagraoui, Jalila, Laramée, Louise, Gendron, Patrick, Jouan, Loubna, Jammali, Safa, Paré, Bastien, Simpson, Shawn M, Tran, Thai Hoa, Duval, Michel, Teira, Pierre, Bittencourt, Henrique, Santiago, Raoul, Barabé, Frédéric, Sauvageau, Guy, Smith, Martin A, Hébert, Josée, Roux, Philippe P, Gruber, Tanja A, Lavallée, Vincent-Philippe, Wilhelm, Brian T, Cellot, Sonia

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Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation von Viny, Aaron D., Bowman, Robert L., Liu, Yu, Lavallée, Vincent-Philippe, Eisman, Shira E., Xiao, Wenbin, Durham, Benjamin H., Navitski, Anastasia, Park, Jane, Braunstein, Stephanie, Alija, Besmira, Karzai, Abdul, Csete, Isabelle S., Witkin, Matthew, Azizi, Elham, Baslan, Timour, Ott, Christopher J., Pe’er, Dana, Dekker, Job, Koche, Richard, Levine, Ross L.

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The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias von Lavallée, Vincent-Philippe, Baccelli, Irène, Krosl, Jana, Wilhelm, Brian, Barabé, Frédéric, Gendron, Patrick, Boucher, Geneviève, Lemieux, Sébastien, Marinier, Anne, Meloche, Sylvain, Hébert, Josée, Sauvageau, Guy

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Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia von Krosl, Jana, Bordeleau, Marie-Eve, Moison, Céline, MacRae, Tara, Boivin, Isabel, Mayotte, Nadine, Gracias, Deanne, Baccelli, Irène, Lavallée, Vincent-Philippe, Bisaillon, Richard, Lehnertz, Bernhard, Mendoza-Sanchez, Rodrigo, Ruel, Réjean, Bertomeu, Thierry, Coulombe-Huntington, Jasmin, Boucher, Geneviève, Noronha, Nandita, Pabst, Caroline, Tyers, Mike, Gendron, Patrick, Lemieux, Sébastien, Barabé, Frédéric, Marinier, Anne, Hébert, Josée, Sauvageau, Guy

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Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors von Lavallée, Vincent-Philippe, Krosl, Jana, Lemieux, Sébastien, Boucher, Geneviève, Gendron, Patrick, Pabst, Caroline, Boivin, Isabel, Marinier, Anne, Guidos, Cynthia J., Meloche, Sylvain, Hébert, Josée, Sauvageau, Guy

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GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo von Pabst, Caroline, Bergeron, Anne, Lavallée, Vincent-Philippe, Yeh, Jonathan, Gendron, Patrick, Norddahl, Gudmundur L., Krosl, Jana, Boivin, Isabel, Deneault, Eric, Simard, Jessica, Imren, Suzan, Boucher, Geneviève, Eppert, Kolja, Herold, Tobias, Bohlander, Stefan K., Humphries, Keith, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy, Barabé, Frédéric

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EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations von Lavallée, Vincent-Philippe, Gendron, Patrick, Lemieux, Sébastien, D’Angelo, Giovanni, Hébert, Josée, Sauvageau, Guy

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High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML von Simon, Laura, Spinella, Jean-François, Yao, Chi-Yuan, Lavallée, Vincent-Philippe, Boivin, Isabel, Boucher, Geneviève, Audemard, Eric, Bordeleau, Marie-Eve, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy

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Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers von Rouette, Alexandre, Trofimov, Assya, Haberl, David, Boucher, Geneviève, Lavallée, Vincent-Philippe, D’Angelo, Giovanni, Hébert, Josée, Sauvageau, Guy, Lemieux, Sébastien, Perreault, Claude

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RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature von Lavallée, Vincent-Philippe, Lemieux, Sébastien, Boucher, Geneviève, Gendron, Patrick, Boivin, Isabel, Armstrong, Richard N., Sauvageau, Guy, Hébert, Josée

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Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML von Garg, Swati, Reyes-Palomares, Armando, He, Lixiazi, Bergeron, Anne, Lavallée, Vincent-Philippe, Lemieux, Sébastien, Gendron, Patrick, Rohde, Christian, Xia, Jianglong, Jagdhane, Prarabdha, Müller-Tidow, Carsten, Lipka, Daniel B., Imren, Suzan, Humphries, R. Keith, Waskow, Claudia, Vick, Binje, Jeremias, Irmela, Richard-Carpentier, Guillaume, Hébert, Josée, Sauvageau, Guy, Zaugg, Judith B., Barabé, Frédéric, Pabst, Caroline

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Liver sinusoidal endothelial cells induce BMP6 expression in response to non–transferrin-bound iron von Charlebois, Edouard, Fillebeen, Carine, Presley, John, Cagnone, Gael, Lisi, Véronique, Lavallée, Vincent-Philippe, Joyal, Jean-Sébastien, Pantopoulos, Kostas

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Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin von Lavallée, Vincent-Philippe, Chagraoui, Jalila, MacRae, Tara, Marquis, Miriam, Bonnefoy, Arnaud, Krosl, Jana, Lemieux, Sébastien, Marinier, Anne, Pabst, Caroline, Rivard, Georges-Étienne, Hébert, Josée, Sauvageau, Guy

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