Uridine-induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites von PETERS, G. J, VAN GRROENINGEN, C. J, LAURENSSE, E. J, LANKELMA, J, LEYVA, A, PINEDO, H. M

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In vivo inhibition of the pyrimidine de novo enzyme dihydroorotic acid dehydrogenase by brequinar sodium (DUP-785;NSC 368390) in mice and patients von PETERS, G. J, SCHWARSTMANN, G, NADAL, J. C, LAURENSSE, E. J, VAN GROENINGEN, C. J, VAN DER VIJGH, W. J. F, PINEDO, H. M

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Retention of in vivo antipyrimidine effects of brequinar sodium (DUP-785; NSC 368390) in murine liver, bone marrow and colon cancer von Peters, G.J., Nadal, J.C., Laurensse, E.J., de Kant, E., Pinedo, H.M.

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A comparison of 5‐fluorouracil metabolism in human colorectal cancer and colon mucosa von Peters, Godefridus J., van Groeningen, Cees J., Laurensse, Emile J., Pinedo, Herbert M.

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Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes von Peters, G J, Braakhuis, B J, de Bruijn, E A, Laurensse, E J, van Walsum, M, Pinedo, H M

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A sensitive non-radioactive assay for pyrimidine nucleoside phosphorylase using reversed-phase high performance liquid chromatography von Laurensse, Emile J., Pinedo, Herbert M., Peters, Godefridus J.

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Enhanced therapeutic efficacy of 5' deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes von PETERS, G. J, BRAAKHUIS, B. J. M, DE BRUIJN, E. A, LAURENSSE, E. J, VAN WALSUM, M, PINEDO, H. M

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Tissue homogenization using a micro-dismembrator for the measurement of enzyme activities von Peters, Godefridus J., Laurensse, Emile J., Leyva, Albert, Pinedo, Herbert M.

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Thymidylate synthase from untreated human colorectal cancer and colonic mucosa: Enzyme activity and inhibition by 5-fluoro-2′-deoxyuridine-5′-monophosphate von Peters, Godefridus J., van Groeningen, Cees J., Laurensse, Emile J., Pinedo, Herbert M.

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Uridine induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites von Peters, G. J., van Groeningen, C. J., Laurensse, E. J., Lankelma, J., Leyva, A., Pinedo, H. M.

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Uridine-induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites von Peters, G. J., van Groeningen, C. J., Laurensse, E. J., Lankelma, J., Leyva, A., Pinedo, H. M.

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TOXICITY AND ANTITUMOR EFFECT OF 5-FLUOROURACIL (FU) 157 AND ITS RESCUE BY URIDINE (UR): 157 von Peters, G J, Van Dijk, J, Van Groeninqen, C, Laurensse, E J, Leyva, A, Lankelma, J, Pinedo, H M

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Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouridine in relation to drug-metabolizing enzymes von PETERS, G. J, LAURENSSE, E, LEYVA, A, LANKELMA, J, PINEDO, H. M

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Reversal of 5-Fluorouracil-Induced Myelosuppression by Prolonged Administration of High-Dose Uridine von Groeningen, C.J. van, Peters, G.J., Leyva, A., Laurensse, E., Pinedo, H.M.

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In vitro biochemical and in vivo biological studies of the uridine rescue of 5-fluorouracil von PETERS, G. J, VAN DIJK, J, LAURENSSE, E, VAN GROENINGEN, C. J, LANKELMA, J, LEYVA, A, NADAL, J. C, PINEDO, H. M

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Clinical and Pharmacologic Study of Orally Administrated Uridine von Van Groeningen, G. J., Peters, G.J., Nadal, J. C., Laurensse, E., Pinedo, H. M.

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Inhibition of pyrimidine de novo synthesis by DUP-785 (NSC 368390) von Peters, G J, Sharma, S L, Laurensse, E, Pinedo, H M

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DUP 785 (NSC 368390): Schedule-dependency of growth-inhibitory and antipyrimidine effects von Schwartsmann, G., Peters, G.J., Laurensse, E., de Waal, F.C., Loonen, A.H., Leyva, A., Pinedo, H.M.

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Effect of pyrimidine nucleosides on body temperatures of man and rabbit in relation to pharmacokinetic data von PETERS, G. J, VAN GROENINGEN, C. J, LAURENSSE, E, KRAAL, I, LEYVA, A, LANKELMA, J, PINEDO, H. M

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A sensitive, nonradiometric assay for dihydroorotic acid dehydrogenase using anion-exchange high-performance liquid chromatography von Peters, G.J., Laurensse, E., Leyva, A., Pinedo, H.M.

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